Genomics of Chromosome Architecture and Dynamics in Single Cells

Publications

Peer reviewed articles (6)

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks

Author(s): Eva K. Brinkman, Tao Chen, Marcel de Haas, Hanna A. Holland, Waseem Akhtar, Bas van Steensel
Published in: Molecular Cell, Issue 70/5, 2018, Page(s) 801-813.e6, ISSN 1097-2765
DOI: 10.1016/j.molcel.2018.04.016

Easy quantification of template-directed CRISPR/Cas9 editing

Author(s): Eva K Brinkman, Arne N Kousholt, Tim Harmsen, Christ Leemans, Tao Chen, Jos Jonkers, Bas van Steensel
Published in: Nucleic Acids Research, Issue 46/10, 2018, Page(s) e58-e58, ISSN 0305-1048
DOI: 10.1093/nar/gky164

High-throughput identification of human SNPs affecting regulatory element activity

Author(s): Joris van Arensbergen, Ludo Pagie, Vincent D. FitzPatrick, Marcel de Haas, Marijke P. Baltissen, Federico Comoglio, Robin H. van der Weide, Hans Teunissen, Urmo Võsa, Lude Franke, Elzo de Wit, Michiel Vermeulen, Harmen J. Bussemaker, Bas van Steensel
Published in: Nature Genetics, Issue 51/7, 2019, Page(s) 1160-1169, ISSN 1061-4036
DOI: 10.1038/s41588-019-0455-2

The role of transcription in shaping the spatial organization of the genome

Author(s): Bas van Steensel, Eileen E. M. Furlong
Published in: Nature Reviews Molecular Cell Biology, Issue 20/6, 2019, Page(s) 327-337, ISSN 1471-0072
DOI: 10.1038/s41580-019-0114-6

The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a

Author(s): Alexey V. Pindyurin, Artem A. Ilyin, Anton V. Ivankin, Mikhail V. Tselebrovsky, Valentina V. Nenasheva, Elena A. Mikhaleva, Ludo Pagie, Bas van Steensel, Yuri Y. Shevelyov
Published in: Epigenetics & Chromatin, Issue 11/1, 2018, ISSN 1756-8935
DOI: 10.1186/s13072-018-0235-8

Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs

Author(s): Christ Leemans, Marloes C.H. van der Zwalm, Laura Brueckner, Federico Comoglio, Tom van Schaik, Ludo Pagie, Joris van Arensbergen, Bas van Steensel
Published in: Cell, Issue 177/4, 2019, Page(s) 852-864.e14, ISSN 0092-8674
DOI: 10.1016/j.cell.2019.03.009