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Elucidating natural bilayer lipid environments

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Publications

Ligand binding to a G protein–coupled receptor captured in a mass spectrometer

Author(s): Hsin-Yung Yen, Jonathan T. S. Hopper, Idlir Liko, Timothy M. Allison, Ya Zhu, Dejian Wang, Monika Stegmann, Shabaz Mohammed, Beili Wu, Carol V. Robinson
Published in: Science Advances, Issue 3/6, 2017, Page(s) e1701016, ISSN 2375-2548
DOI: 10.1126/sciadv.1701016

Identifying key membrane protein lipid interactions using mass spectrometry

Author(s): Kallol Gupta, Jingwen Li, Idlir Liko, Joseph Gault, Cherine Bechara, Di Wu, Jonathan T S Hopper, Kevin Giles, Justin L P Benesch, Carol V Robinson
Published in: Nature Protocols, Issue 13/5, 2018, Page(s) 1106-1120, ISSN 1754-2189
DOI: 10.1038/nprot.2018.014

Native Desorption Electrospray Ionization Liberates Soluble and Membrane Protein Complexes from Surfaces

Author(s): Stephen Ambrose, Nicholas G. Housden, Kallol Gupta, Jieyuan Fan, Paul White, Hsin-Yung Yen, Julien Marcoux, Colin Kleanthous, Jonathan T. S. Hopper, Carol V. Robinson
Published in: Angewandte Chemie International Edition, Issue 56/46, 2017, Page(s) 14463-14468, ISSN 1433-7851
DOI: 10.1002/anie.201704849

PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

Author(s): Hsin-Yung Yen, Kin Kuan Hoi, Idlir Liko, George Hedger, Michael R. Horrell, Wanling Song, Di Wu, Philipp Heine, Tony Warne, Yang Lee, Byron Carpenter, Andreas Plückthun, Christopher G. Tate, Mark S. P. Sansom, Carol V. Robinson
Published in: Nature, Issue 559/7714, 2018, Page(s) 423-427, ISSN 0028-0836
DOI: 10.1038/s41586-018-0325-6

Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry

Author(s): Dror S. Chorev, Lindsay A. Baker, Di Wu, Victoria Beilsten-Edmands, Sarah L. Rouse, Tzviya Zeev-Ben-Mordehai, Chimari Jiko, Firdaus Samsudin, Christoph Gerle, Syma Khalid, Alastair G. Stewart, Stephen J. Matthews, Kay Grünewald, Carol V. Robinson
Published in: Science, Issue 362/6416, 2018, Page(s) 829-834, ISSN 0036-8075
DOI: 10.1126/science.aau0976

The role of interfacial lipids in stabilizing membrane protein oligomers

Author(s): Kallol Gupta, Joseph A. C. Donlan, Jonathan T. S. Hopper, Povilas Uzdavinys, Michael Landreh, Weston B. Struwe, David Drew, Andrew J. Baldwin, Phillip J. Stansfeld, Carol V. Robinson
Published in: Nature, Issue 541/7637, 2017, Page(s) 421-424, ISSN 0028-0836
DOI: 10.1038/nature20820

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

Author(s): Michael Landreh, Erik G. Marklund, Povilas Uzdavinys, Matteo T. Degiacomi, Mathieu Coincon, Joseph Gault, Kallol Gupta, Idlir Liko, Justin L. P. Benesch, David Drew, Carol V. Robinson
Published in: Nature Communications, Issue 8, 2017, Page(s) 13993, ISSN 2041-1723
DOI: 10.1038/ncomms13993

From molecular chaperones to membrane motors: through the lens of a mass spectrometrist

Author(s): Carol V. Robinson
Published in: Biochemical Society Transactions, Issue 45/1, 2017, Page(s) 251-260, ISSN 0300-5127
DOI: 10.1042/bst20160395