A paradigm shift in cancer therapy – using mitochondria-powered chemiluminescence to non-invasively treat inaccessible tumours

Informazioni relative al progetto

Lumiblast

ID dell’accordo di sovvenzione: 712921

DOI 10.3030/712921

Progetto chiuso

Data della firma CE 16 Maggio 2016

Data di avvio 1 Ottobre 2016

Data di completamento 31 Gennaio 2023

Finanziato da

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Costo totale € 3 031 375,00

Contributo UE € 3 031 375,00

Coordinato da

OSLO UNIVERSITETSSYKEHUS HF
Norway

Risultati finali

Other (2)

Publications

At least five publications in peerreviewed open access journals

Scientific symposium

Scientific symposium (final project event) on Lumiblast Technologies.

Websites, patent fillings, videos etc. (1)

Project website

Project website including some special features.

Pubblicazioni

Peer reviewed articles (6)

Building a Functionalizable, Potent Chemiluminescent Agent: A Rational Design Study on 6,8-Substituted Luminol Derivatives.

Autori: Mikroulis T, Cuquerella MC, Giussani A, Pantelia A, Rodríguez-Muñiz GM, Rotas G, Roca-Sanjuán D, Miranda MA, Vougioukalakis GC
Pubblicato in: Journal of Organic Chemistry, 2021, ISSN 1520-6904
Editore: Americam Cancer Society
DOI: 10.1021/acs.joc.1c00890

Cytotoxic and Photocytotoxic Effects of Cercosporin on Human Tumor Cell Lines

Autori: Maria Mastrangelopoulou, Mantas Grigalavicius, Kristian Berg, Mathilde Ménard, Theodossis A. Theodossiou
Pubblicato in: Photochemistry and Photobiology, Numero 95/1, 2019, Pagina/e 387-396, ISSN 0031-8655
Editore: American Society for Photobiology
DOI: 10.1111/php.12997

Synthesis and Chemiluminescent Properties of Amino-Acylated luminol Derivatives Bearing Phosphonium Cations

Autori: Pantelia, Daskalaki, Cuquerella, Rotas, Miranda, Vougioukalakis
Pubblicato in: Molecules, Numero 24/21, 2019, Pagina/e 3957, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24213957

Photodynamic efficacy of cercosporin in 3D tumor cell cultures

Autori: Mantas Grigalavicius, Maria Mastrangelopoulou, Delmon Arous, Asta Juzeniene, Mathilde Ménard, Ellen Skarpen, Kristian Berg, Theodossis A. Theodossiou
Pubblicato in: Photochemistry and Photobiology, 2020, ISSN 0031-8655
Editore: American Society for Photobiology
DOI: 10.1111/php.13257

Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances.

Autori: Mastrangelopoulou M, Grigalavicius M, Raabe TH, Skarpen E, Juzenas P, Peng Q, Berg K, Theodossiou TA.
Pubblicato in: Cancer Rep (Hoboken), 2020, ISSN 2573-8348
Editore: Wiley Periodicals LLC
DOI: 10.1002/cnr2.1278

Modulation by Phosphonium Ions of the Activity of Mitotropic Agents Based on the Chemiluminescence of Luminols.

Autori: Rodríguez-Muñiz GM, Mikroulis T, Pantelia A, Rotas G, Cuquerella MC, Vougioukalakis GC, Miranda MA.
Pubblicato in: Molecules, 2022, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27041245

Diritti di proprietà intellettuale

Patent (3)

METHOD

Numero candidatura/pubblicazione: 20 18051744
Data: 2018-06-21
Candidato/i: ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON

METHOD

Numero candidatura/pubblicazione: 20 18051744
Data: 2018-06-21

METHOD

Numero candidatura/pubblicazione: 20 18051744
Data: 2018-06-21