Chemistry and Biology in Synergy - Studies of hydrogenases using a combination of synthetic chemistry and biological tools

Informazioni relative al progetto

CaBiS

ID dell’accordo di sovvenzione: 714102

DOI 10.3030/714102

Progetto chiuso

Data della firma CE 14 Novembre 2016

Data di avvio 1 Febbraio 2017

Data di completamento 31 Gennaio 2022

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 494 880,00

Contributo UE € 1 494 880,00

Coordinato da

UPPSALA UNIVERSITET
Sweden

Pubblicazioni

Peer reviewed articles (13)

The reactivity of molecular oxygen and reactive oxygen species with [FeFe] hydrogenase biomimetics: reversibility and the role of the second coordination sphere

Autori: Vincent C.-C. Wang, Charlène Esmieu, Holly J. Redman, Gustav Berggren, Leif Hammarström
Pubblicato in: Dalton Transactions, Numero 49/3, 2020, Pagina/e 858-865, ISSN 1477-9226
Editore: Royal Society of Chemistry
DOI: 10.1039/c9dt04618f

[FeFe]-hydrogenase maturation : H-cluster assembly intermediates tracked by electron paramagnetic resonance, infrared, and X-ray absorption spectroscopy

Autori: Brigitta Németh; Moritz Senger; Holly J. Redman; Pierre Ceccaldi; Joan B. Broderick; Ann Magnuson; Sven T. Stripp; Michael Haumann; Gustav Berggren
Pubblicato in: Journal of Biological Inorganic Chemistry, Numero 1, 2020, ISSN 1432-1327
Editore: Springer Nature
DOI: 10.26434/chemrxiv.12168303

Characterization of a putative sensory [FeFe]-hydrogenase provides new insight into the role of the active site architecture

Autori: Henrik Land, Alina Sekretareva, Ping Huang, Holly J. Redman, Brigitta Németh, Nakia Polidori, Lívia S. Mészáros, Moritz Senger, Sven T. Stripp, Gustav Berggren
Pubblicato in: Chemical Science, Numero 11/47, 2020, Pagina/e 12789-12801, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d0sc03319g

The maturase HydF enables [FeFe] hydrogenase assembly via transient, cofactor-dependent interactions

Autori: Brigitta Németh, Henrik Land, Ann Magnuson, Anders Hofer, Gustav Berggren
Pubblicato in: Journal of Biological Chemistry, Numero 295/33, 2020, Pagina/e 11891-11901, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra119.011419

From protein engineering to artificial enzymes – biological and biomimetic approaches towards sustainable hydrogen production

Autori: C. Esmieu, P. Raleiras, G. Berggren
Pubblicato in: Sustainable Energy & Fuels, Numero 2/4, 2018, Pagina/e 724-750, ISSN 2398-4902
Editore: The Royal Society of Chemistry
DOI: 10.1039/C7SE00582B

In vivo activation of an [FeFe] hydrogenase using synthetic cofactors

Autori: N. Khanna, C. Esmieu, L. S. Mészáros, P. Lindblad, G. Berggren
Pubblicato in: Energy & Environmental Science, Numero 10/7, 2017, Pagina/e 1563-1567, ISSN 1754-5692
Editore: Royal Society of Chemistry
DOI: 10.1039/C7EE00135E

In Vivo EPR Characterization of Semi-Synthetic [FeFe] Hydrogenases

Autori: Lívia S. Mészáros, Brigitta Németh, Charlène Esmieu, Pierre Ceccaldi, Gustav Berggren
Pubblicato in: Angewandte Chemie International Edition, Numero 57/10, 2018, Pagina/e 2596-2599, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201710740

Generation of a functional, semisynthetic [FeFe]-hydrogenase in a photosynthetic microorganism

Autori: Adam Wegelius, Namita Khanna, Charlène Esmieu, Giovanni Davide Barone, Filipe Pinto, Paula Tamagnini, Gustav Berggren, Peter Lindblad
Pubblicato in: Energy & Environmental Science, Numero 11/11, 2018, Pagina/e 3163-3167, ISSN 1754-5692
Editore: Royal Society of Chemistry
DOI: 10.1039/c8ee01975d

Monitoring H-cluster assembly using a semi-synthetic HydF protein

Autori: Brigitta Németh, Charlène Esmieu, Holly J. Redman, Gustav Berggren
Pubblicato in: Dalton Transactions, Numero 48/18, 2019, Pagina/e 5978-5986, ISSN 1477-9226
Editore: Royal Society of Chemistry
DOI: 10.1039/c8dt04294b

Synthesis of a miniaturized [FeFe] hydrogenase model system

Autori: Charlène Esmieu, Meiyuan Guo, Holly J. Redman, Marcus Lundberg, Gustav Berggren
Pubblicato in: Dalton Transactions, Numero 48/7, 2019, Pagina/e 2280-2284, ISSN 1477-9226
Editore: Royal Society of Chemistry
DOI: 10.1039/c8dt05085f

Spectroscopic investigations under whole cell conditions provide new insight into the metal hydride chemistry of [FeFe]-hydrogenase

Autori: Lívia Mészáros, Pierre Ceccaldi, Marco Lorenzi, Holly Jayne Redman, Emanuel Pfitzner, Joachim Heberle, Moritz Senger, Sven Timo Stripp, Gustav Berggren
Pubblicato in: Chemical Science, 2020, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d0sc00512f

Discovery of novel [FeFe]-hydrogenases for biocatalytic H 2 -production

Autori: Henrik Land, Pierre Ceccaldi, Lívia S. Mészáros, Marco Lorenzi, Holly J. Redman, Moritz Senger, Sven T. Stripp, Gustav Berggren
Pubblicato in: Chemical Science, Numero 10/43, 2019, Pagina/e 9941-9948, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/c9sc03717a

Semi-synthetic hydrogenases—in vitro and in vivo applications

Autori: Lívia S. Mészáros; Henrik Land; Holly J. Redman; Gustav Berggren
Pubblicato in: Current Opinion in Green and Sustainable Chemistry, 2021, ISSN 2452-2236
Editore: Elsevier
DOI: 10.1016/j.cogsc.2021.100521