Novel Mechanism of Behavioural Change

Projektinformationen

ChangeBehavNeuro

ID Finanzhilfevereinbarung: 715016

DOI

10.3030/715016

Projekt abgeschlossen

EK-Unterschriftsdatum 15 Dezember 2016

Startdatum 1 Januar 2017

Enddatum 31 Dezember 2022

Finanziert unter

• EXCELLENT SCIENCE - European Research Council (ERC)

Gesamtkosten

€ 1 500 000,00

EU-Beitrag

€ 1 500 000,00

Koordiniert durch

TEL AVIV UNIVERSITY
Israel

Periodic Reporting for period 4 - ChangeBehavNeuro (Novel Mechanism of Behavioural Change)

Berichtszeitraum: 2021-07-01 bis 2022-12-31

Zusammenfassung vom Kontext und den Gesamtzielen des Projekts

Understanding how values of different options that lead to choice are represented in the brain is a basic scientific question with far reaching implications. The far-reaching goal of this project was to study the mechanism, by which low-level sensory, perceptual and motor neural processes underlie value representation and change in the human brain even in the absence of external reinforcement. Multiple disorders can benefit from behavioural change such as addictions, mental and food disorders. Current methods of behavioural change rely on self-control or external reinforcement. Here, we explored the behavioral boundaries and neural basis of a novel mechanism of behavioral change that does not rely on external feedback or self-control. We studied the behavioral and neural differences between reinforced and non-reinforced change and how memory is related to value-based decision-making. We showed how low-level features influence the neural representation of value. We tested the interaction with the known striatal representation of reinforced behavioural change, which has been the main focus of research thus far. Finally, the project culminated in an opinion paper of a novel non-reinforced pathway in the brain that will influence development of future interventions for mental disorders and addictions.

Arbeit, die ab Beginn des Projekts bis zum Ende des durch den Bericht erfassten Berichtszeitraums geleistet wurde, und die wichtigsten bis dahin erzielten Ergebnisse

We investigated the generalizability and boundaries of the novel non-reinforced behavioral change effect and reveled that this novel mechanism of behavioral change relies on changes in visual sensory mechanisms. We further developed a new behavioural task to change behavior with reinforcement as well study the neural basis of reinforced habits in humans.

Fortschritte, die über den aktuellen Stand der Technik hinausgehen und voraussichtliche potenzielle Auswirkungen (einschließlich der bis dato erzielten sozioökonomischen Auswirkungen und weiter gefassten gesellschaftlichen Auswirkungen des Projekts)

We have published 9 manuscrips. We expect additional 1-2 papers to be published in the coming years.

Potential novel neural pathway for Nonreinforced preference change