Novel Mechanism of Behavioural Change

Informazioni relative al progetto

ChangeBehavNeuro

ID dell’accordo di sovvenzione: 715016

DOI

10.3030/715016

Progetto chiuso

Data della firma CE 15 Dicembre 2016

Data di avvio 1 Gennaio 2017

Data di completamento 31 Dicembre 2022

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 500 000,00

Contributo UE

€ 1 500 000,00

Coordinato da

TEL AVIV UNIVERSITY
Israel

Periodic Reporting for period 4 - ChangeBehavNeuro (Novel Mechanism of Behavioural Change)

Periodo di rendicontazione: 2021-07-01 al 2022-12-31

Sintesi del contesto e degli obiettivi generali del progetto

Understanding how values of different options that lead to choice are represented in the brain is a basic scientific question with far reaching implications. The far-reaching goal of this project was to study the mechanism, by which low-level sensory, perceptual and motor neural processes underlie value representation and change in the human brain even in the absence of external reinforcement. Multiple disorders can benefit from behavioural change such as addictions, mental and food disorders. Current methods of behavioural change rely on self-control or external reinforcement. Here, we explored the behavioral boundaries and neural basis of a novel mechanism of behavioral change that does not rely on external feedback or self-control. We studied the behavioral and neural differences between reinforced and non-reinforced change and how memory is related to value-based decision-making. We showed how low-level features influence the neural representation of value. We tested the interaction with the known striatal representation of reinforced behavioural change, which has been the main focus of research thus far. Finally, the project culminated in an opinion paper of a novel non-reinforced pathway in the brain that will influence development of future interventions for mental disorders and addictions.

Lavoro eseguito dall’inizio del progetto fino alla fine del periodo coperto dalla relazione e principali risultati finora ottenuti

We investigated the generalizability and boundaries of the novel non-reinforced behavioral change effect and reveled that this novel mechanism of behavioral change relies on changes in visual sensory mechanisms. We further developed a new behavioural task to change behavior with reinforcement as well study the neural basis of reinforced habits in humans.

Progressi oltre lo stato dell’arte e potenziale impatto previsto (incluso l’impatto socioeconomico e le implicazioni sociali più ampie del progetto fino ad ora)

We have published 9 manuscrips. We expect additional 1-2 papers to be published in the coming years.

Potential novel neural pathway for Nonreinforced preference change