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Training European Network: Metabolic Dysfunctions associated with Pharmacological Treatment of Schizophrenia

Deliverables

Researchers Declarations

Researchers declarations

Supervisory Board of the network

Supervisory Board of the network

Research Training schools/Meetings, and reports 3

Research Training schools/Meetings, and reports 3 (report M21)

Dissemination report 1

Open Dissemination report on scientific publications, presentations of results, networking & public engagement activities (Month 24)

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Publications

Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis

Author(s): Águeda González-Rodríguez, M. Pilar Valdecantos, Patricia Rada, Annalisa Addante, Inés Barahona, Esther Rey, Virginia Pardo, Laura Ruiz, Laura M. Laiglesia, María J. Moreno-Aliaga, Carmelo García-Monzón, Aránzazu Sánchez, Ángela M. Valverde
Published in: Molecular Metabolism, Issue 7, 2018, Page(s) 132-146, ISSN 2212-8778
DOI: 10.1016/j.molmet.2017.10.008

IGF-1, Inflammation and Retinal Degeneration: A Close Network

Author(s): Ana I. Arroba, Antonio Campos-Caro, Manuel Aguilar-Diosdado, Ángela M. Valverde
Published in: Frontiers in Aging Neuroscience, Issue 10, 2018, ISSN 1663-4365
DOI: 10.3389/fnagi.2018.00203

Taurine Supplementation Alleviates Puromycin Aminonucleoside Damage by Modulating Endoplasmic Reticulum Stress and Mitochondrial-Related Apoptosis in Rat Kidney

Author(s): Alessandra Stacchiotti, Gaia Favero, Antonio Lavazza, Maria Monsalve, Luigi Rodella, Rita Rezzani
Published in: Nutrients, Issue 10/6, 2018, Page(s) 689, ISSN 2072-6643
DOI: 10.3390/nu10060689

Protection against gamma-radiation injury by protein tyrosine phosphatase 1B

Author(s): Marina Mojena, María Pimentel-Santillana, Adrián Povo-Retana, Victoria Fernández-García, Silvia González-Ramos, Patricia Rada, Alberto Tejedor, Daniel Rico, Paloma Martín-Sanz, Angela M. Valverde, Lisardo Boscá
Published in: Redox Biology, Issue 17, 2018, Page(s) 213-223, ISSN 2213-2317
DOI: 10.1016/j.redox.2018.04.018

The sp 2 -iminosugar glycolipid 1-dodecylsulfonyl-5 N ,6 O -oxomethylidenenojirimycin (DSO 2 -ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explants

Author(s): Elena Alcalde-Estévez, Ana I. Arroba, Elena M. Sánchez-Fernández, Carmen Ortiz Mellet, Jose M. García Fernández, Laura Masgrau, Ángela M. Valverde
Published in: Food and Chemical Toxicology, Issue 111, 2018, Page(s) 454-466, ISSN 0278-6915
DOI: 10.1016/j.fct.2017.11.050

Medical and Dietary Uses of N-Acetylcysteine

Author(s): Špela Šalamon, Barbara Kramar, Tinkara Pirc Marolt, Borut Poljšak, Irina Milisav
Published in: Antioxidants, Issue 8/5, 2019, Page(s) 111, ISSN 2076-3921
DOI: 10.3390/antiox8050111

Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases

Author(s): Inmaculada García-Ruiz, Nerea Blanes Ruiz, Patricia Rada, Virginia Pardo, Laura Ruiz, Ana Blas-García, M. Pilar Valdecantos, Montserrat Grau Sanz, José A. Solís Herruzo, Ángela M. Valverde
Published in: Redox Biology, Issue 26, 2019, Page(s) 101263, ISSN 2213-2317
DOI: 10.1016/j.redox.2019.101263

Differential Effects of a Glucagon-Like Peptide 1 Receptor Agonist in Non-Alcoholic Fatty Liver Disease and in Response to Hepatectomy

Author(s): M. Pilar Valdecantos, Laura Ruiz, Virginia Pardo, Luis Castro-Sanchez, Carmelo García-Monzón, Borja Lanzón, Javier Rupérez, Coral Barbas, Jaqueline Naylor, James L. Trevaskis, Joseph Grimsby, Cristina M. Rondinone, Ángela M. Valverde
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
DOI: 10.1038/s41598-018-33949-z

Is the Brain a Key Player in Glucose Regulation and Development of Type 2 Diabetes?

Author(s): Martin H. Lundqvist, Kristina Almby, Niclas Abrahamsson, Jan W. Eriksson
Published in: Frontiers in Physiology, Issue 10, 2019, ISSN 1664-042X
DOI: 10.3389/fphys.2019.00457

Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy

Author(s): Alessandra Stacchiotti, Ilaria Grossi, Raquel García-Gómez, Gaurangkumar Arvindbhai Patel, Alessandro Salvi, Antonio Lavazza, Giuseppina De Petro, Maria Monsalve, Rita Rezzani
Published in: Cells, Issue 8/9, 2019, Page(s) 1053, ISSN 2073-4409
DOI: 10.3390/cells8091053

Effects of aripiprazole on pupillometric parameters related to pharmacokinetics and pharmacogenetics after single oral administration to healthy subjects

Author(s): Dora Koller, Carmen Belmonte, Rubin Lubomirov, Miriam Saiz-Rodríguez, Pablo Zubiaur, Manuel Román, Dolores Ochoa, Antonio Carcas, Aneta Wojnicz, Francisco Abad-Santos
Published in: Journal of Psychopharmacology, Issue 32/11, 2018, Page(s) 1212-1222, ISSN 0269-8811
DOI: 10.1177/0269881118798605

Effects of second-generation antipsychotics on human subcutaneous adipose tissue metabolism

Author(s): Assel Sarsenbayeva, Cátia M. Marques-Santos, Ketan Thombare, Giada Di Nunzio, Kristina E. Almby, Martin Lundqvist, Jan W. Eriksson, Maria J. Pereira
Published in: Psychoneuroendocrinology, 2019, Page(s) 104445, ISSN 0306-4530
DOI: 10.1016/j.psyneuen.2019.104445

Detection of metabolic syndrome burden in healthy young adults may enable timely introduction of disease prevention

Author(s): Anja Šoštarič, Barbara Jenko, Nada Rotovnik Kozjek, Darja Ovijač, Dušan Šuput, Irina Milisav, Vita Dolžan
Published in: Archives of Medical Science, Issue 15/5, 2019, Page(s) 1184-1194, ISSN 1734-1922
DOI: 10.5114/aoms.2019.87462

Beneficial Role of ROS in Cell Survival: Moderate Increases in H2O2 Production Induced by Hepatocyte Isolation Mediate Stress Adaptation and Enhanced Survival

Author(s): Izak Patrik Miller, Ivan Pavlović, Borut Poljšak, Dušan Šuput, Irina Milisav
Published in: Antioxidants, Issue 8/10, 2019, Page(s) 434, ISSN 2076-3921
DOI: 10.3390/antiox8100434

Second-Generation Antipsychotics and Dysregulation of Glucose Metabolism: Beyond Weight Gain

Author(s): Diana Grajales, Vitor Ferreira, Ángela M. Valverde
Published in: Cells, Issue 8/11, 2019, Page(s) 1336, ISSN 2073-4409
DOI: 10.3390/cells8111336

Adipose tissue as a target for second-generation (atypical) antipsychotics: A molecular view

Author(s): Vitor Ferreira, Diana Grajales, Ángela M. Valverde
Published in: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Issue 1865/2, 2020, Page(s) 158534, ISSN 1388-1981
DOI: 10.1016/j.bbalip.2019.158534

Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblasts

Author(s): Ignacio Prieto, Alberto Zambrano, Javier Laso, Ana Aranda, Enrique Samper, María Monsalve
Published in: Free Radical Biology and Medicine, Issue 138, 2019, Page(s) 23-32, ISSN 0891-5849
DOI: 10.1016/j.freeradbiomed.2019.04.015

Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential

Author(s): Ignacio Prieto, Carmen Rubio Alarcón, Raquel García-Gómez, Rebeca Berdún, Tamara Urgel, Manuel Portero, Reinald Pamplona, Antonio Martínez-Ruiz, José Ignacio Ruiz-Sanz, M. Begoña Ruiz-Larrea, Mariona Jove, Sebastián Cerdán, María Monsalve
Published in: Redox Biology, Issue 29, 2020, Page(s) 101396, ISSN 2213-2317
DOI: 10.1016/j.redox.2019.101396

Simultaneous determination of six antipsychotics, two of their metabolites and caffeine in human plasma by LC-MS/MS using a phospholipid-removal microelution-solid phase extraction method for sample preparation

Author(s): Dora Koller, Pablo Zubiaur, Miriam Saiz-Rodríguez, Francisco Abad-Santos, Aneta Wojnicz
Published in: Talanta, Issue 198, 2019, Page(s) 159-168, ISSN 0039-9140
DOI: 10.1016/j.talanta.2019.01.112

The integrated stress response promotes B7H6 expression

Author(s): Akram Obiedat, Yoav Charpak-Amikam, Julie Tai-Schmiedel, Einat Seidel, Mohamed Mahameed, Tony Avril, Noam Stern-Ginossar, Lorraine Springuel, Jennifer Bolsée, David E. Gilham, Priya Dipta, Miriam Shmuel, Eric Chevet, Ofer Mandelboim, Boaz Tirosh
Published in: Journal of Molecular Medicine, Issue 98/1, 2020, Page(s) 135-148, ISSN 0946-2716
DOI: 10.1007/s00109-019-01859-w

Histone modifications associated with nonconventional systemic drug response in moderate-to-severe psoriasis.

Author(s): M.C. Ovejero-Benito, P. Sánchez-Jiménez, M. Saiz-Rodríguez, S. Martín-Vilchez, T. Cabaleiro, M. Román, D. Ochoa, F. Abad-Santos, A. Reolid, E. Muñoz-Aceituno, M. Llamas-Velasco, E. Daudén, F. Abad-Santos
Published in: IBJ Plus, 2018, ISSN 2531-0151
DOI: 10.24217/2531-0151.18v1s1.00007

Effects of olanzapine and aripiprazole on glucose uptake in healthy human subcutaneous adipocytes during short incubations.

Author(s): Catía Marques, Assel Sarsenbayeva, Gretha Boersma, Maria João Pereira, Jan Eriksson, Angela Valverde, Angela Valverde, Eugénia Carvalho
Published in: IBJ Plus, 2018, ISSN 2531-0151
DOI: 10.24217/2531-0151.18v1s1.00008