Resultado final Documents, reports (1) Scientific publications Min. 45 publications in peer-reviewed journals Other (2) Industry course SB and SAB established Websites, patent fillings, videos etc. (2) Website Website www.train2target.eu Science Slams Publicaciones Peer reviewed articles (27) Effective approaches to discover new microbial metabolites in a large strain library. Autores: Mitja M Zdouc, Marianna Iorio, Kristiina Vind, Matteo Simone, Stefania Serina, Cristina Brunati, Paolo Monciardini, Arianna Tocchetti, Guadalupe S Zarazúa, Max Crüsemann, Sonia I Maffioli, Margherita Sosio, Stefano Donadio Publicado en: Journal of Industrial Microbiology and Biotechnology, 2021, ISSN 1476-5535 Editor: Springer-Nature DOI: 10.1093/jimb/kuab017 The active repertoire of Escherichia coli peptidoglycan amidases varies with physiochemical environment Autores: Mueller, Elizabeth A; Iken, Abbygail G; Öztürk, Mehmet; Winkle, Matthias; Schmitz, Mirko; Vollmer, Waldemar; Di Ventura, Barbara; Levin, Petra Anne Publicado en: Molecular Microbiology, 2021, ISSN 0950-382X Editor: Blackwell Publishing Inc. DOI: 10.1111/mmi.14711 Carbohydrate-based adjuvants Autores: Pilar Garcia-Vello, Immacolata Speciale, Fabrizio Chiodo, Antonio Molinaro, Cristina De Castro Publicado en: Drug Discovery Today: Technologies, Issue 35-36, 2020, Page(s) 57-68, ISSN 1740-6749 Editor: Elsevier BV DOI: 10.1016/j.ddtec.2020.09.005 A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters Autores: Mitja M. Zdouc, Mohammad M. Alanjary, Guadalupe S. Zarazúa, Sonia I. Maffioli, Max Crüsemann, Marnix H. Medema, Stefano Donadio, Margherita Sosio Publicado en: Cell Chemical Biology, 2020, ISSN 2451-9456 Editor: Cell Chemical Biology DOI: 10.1016/j.chembiol.2020.11.009 "Detection of in vivo Protein Interactions in All Bacterial Components by Förster Resonance Energy Transfer with the Superfolder mTurquoise2 ox-mNeongreen FRET Pair" Autores: Nils Meiresonne, Elisa Consoli, Laureen Mertens, Tanneke den Blaauwen Publicado en: BIO-PROTOCOL, Issue 9/23, 2019, ISSN 2331-8325 Editor: Bio-protocol DOI: 10.21769/bioprotoc.3448 Lipoproteins in Gram-negative bacteria: new insights into their biogenesis, subcellular targeting and functional roles Autores: Jessica El Rayes, Raquel Rodríguez-Alonso, Jean-François Collet Publicado en: Current Opinion in Microbiology, Issue 61, 2021, Page(s) 25-34, ISSN 1369-5274 Editor: Elsevier BV DOI: 10.1016/j.mib.2021.02.003 Structural features and immunological perception of the cell surface glycans of Lactobacillus plantarum: a novel rhamnose-rich polysaccharide and teichoic acids Autores: Pilar Garcia-Vello, Garima Sharma, Immacolata Speciale, Antonio Molinaro, Sin-Hyeog Im, Cristina De Castro Publicado en: Carbohydrate Polymers, Issue 233, 2020, Page(s) 115857, ISSN 0144-8617 Editor: Pergamon Press Ltd. DOI: 10.1016/j.carbpol.2020.115857 The Lpt ABC transporter for lipopolysaccharide export to the cell surface Autores: Paola Sperandeo, Alessandra M. Martorana, Alessandra Polissi Publicado en: Research in Microbiology, Issue 170/8, 2019, Page(s) 366-373, ISSN 0923-2508 Editor: Elsevier BV DOI: 10.1016/j.resmic.2019.07.005 Planomonospora : A Metabolomics Perspective on an Underexplored Actinobacteria Genus Autores: Mitja M. Zdouc, Marianna Iorio, Sonia I. Maffioli, Max Crüsemann, Stefano Donadio, Margherita Sosio Publicado en: Journal of Natural Products, Issue 84/2, 2021, Page(s) 204-219, ISSN 0163-3864 Editor: American Chemical Society DOI: 10.1021/acs.jnatprod.0c00807 In vitro activity of rifabutin against 293 contemporary carbapenem-resistant Acinetobacter baumannii clinical isolates and characterization of rifabutin mode of action and resistance mechanisms Autores: Vincent Trebosc, Birgit Schellhorn, Julian Schill, Valentina Lucchini, Jacqueline Bühler, Marilyne Bourotte, Jonathan J Butcher, Marc Gitzinger, Sergio Lociuro, Christian Kemmer, Glenn E Dale Publicado en: Journal of Antimicrobial Chemotherapy, Issue 75/12, 2020, Page(s) 3552-3562, ISSN 0305-7453 Editor: Oxford University Press DOI: 10.1093/jac/dkaa370 The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes Autores: Robert M. Cleverley, Zoe J. Rutter, Jeanine Rismondo, Federico Corona, Ho-Ching Tiffany Tsui, Fuad A. Alatawi, Richard A. Daniel, Sven Halbedel, Orietta Massidda, Malcolm E. Winkler, Richard J. Lewis Publicado en: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723 Editor: Nature Publishing Group DOI: 10.1038/s41467-018-08056-2 Thanatin Impairs Lipopolysaccharide Transport Complex Assembly by Targeting LptC–LptA Interaction and Decreasing LptA Stability Autores: Elisabete C. C. M. Moura, Tiago Baeta, Alessandra Romanelli, Cedric Laguri, Alessandra M. Martorana, Emanuela Erba, Jean-Pierre Simorre, Paola Sperandeo, Alessandra Polissi Publicado en: Frontiers in Microbiology, Issue 11, 2020, ISSN 1664-302X Editor: Frontiers Media DOI: 10.3389/fmicb.2020.00909 ActS activates peptidoglycan amidases during outer membrane stress in Escherichia coli Autores: Carlos K. Gurnani Serrano, Matthias Winkle, Alessandra M. Martorana, Jacob Biboy, Niccolo Morè, Patrick Moynihan, Manuel Banzhaf, Waldemar Vollmer, Alessandra Polissi Publicado en: Molecular Microbiology, 2021, ISSN 0950-382X Editor: Blackwell Publishing Inc. DOI: 10.1111/mmi.14712 The lipopolysaccharide transport (Lpt) machinery: A nonconventional transporter for lipopolysaccharide assembly at the outer membrane of Gram-negative bacteria Autores: Paola Sperandeo, Alessandra M. Martorana, Alessandra Polissi Publicado en: Journal of Biological Chemistry, Issue 292/44, 2017, Page(s) 17981-17990, ISSN 0021-9258 Editor: American Society for Biochemistry and Molecular Biology Inc. DOI: 10.1074/jbc.R117.802512 Copper inhibits peptidoglycan LD-transpeptidases suppressing β-lactam resistance due to bypass of penicillin-binding proteins Autores: Katharina Peters, Manuel Pazos, Zainab Edoo, Jean-Emmanuel Hugonnet, Alessandra M. Martorana, Alessandra Polissi, Michael S. VanNieuwenhze, Michel Arthur, Waldemar Vollmer Publicado en: Proceedings of the National Academy of Sciences, Issue 115/42, 2018, Page(s) 10786-10791, ISSN 0027-8424 Editor: National Academy of Sciences DOI: 10.1073/pnas.1809285115 Interaction of lipopolysaccharides at intermolecular sites of the periplasmic Lpt transport assembly Autores: Cedric Laguri, Paola Sperandeo, Kevin Pounot, Isabel Ayala, Alba Silipo, Catherine M. Bougault, Antonio Molinaro, Alessandra Polissi, Jean-Pierre Simorre Publicado en: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322 Editor: Nature Publishing Group DOI: 10.1038/s41598-017-10136-0 Superfolder mTurquoise2 ox optimized for the bacterial periplasm allows high efficiency in vivo FRET of cell division antibiotic targets Autores: Nils Y. Meiresonne, Elisa Consoli, Laureen M. Y. Mertens, Anna Chertkova, Joachim Goedhart, Tanneke den Blaauwen Publicado en: Molecular Microbiology, 2019, ISSN 0950-382X Editor: Blackwell Publishing Inc. DOI: 10.1111/mmi.14206 Solid State NMR Studies of Intact Lipopolysaccharide Endotoxin Autores: Cedric Laguri, Alba Silipo, Alessandra M. Martorana, Paul Schanda, Roberta Marchetti, Alessandra Polissi, Antonio Molinaro, Jean-Pierre Simorre Publicado en: ACS Chemical Biology, Issue 13/8, 2018, Page(s) 2106-2113, ISSN 1554-8929 Editor: American Chemical Society DOI: 10.1021/acschembio.8b00271 Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect Autores: Niccolò Morè, Alessandra M. Martorana, Jacob Biboy, Christian Otten, Matthias Winkle, Carlos K. Gurnani Serrano, Alejandro Montón Silva, Lisa Atkinson, Hamish Yau, Eefjan Breukink, Tanneke den Blaauwen, Waldemar Vollmer, Alessandra Polissi Publicado en: mBio, Issue 10/1, 2019, ISSN 2150-7511 Editor: American Society for Microbiology DOI: 10.1128/mbio.02729-18 Structural insight into the formation of lipoprotein-β-barrel complexes Autores: Raquel Rodríguez-Alonso, Juliette Létoquart, Van Son Nguyen, Gwennaelle Louis, Antonio N. Calabrese, Bogdan I. Iorga, Sheena E. Radford, Seung-Hyun Cho, Han Remaut, Jean-François Collet Publicado en: Nature Chemical Biology, Issue 16/9, 2020, Page(s) 1019-1025, ISSN 1552-4450 Editor: Nature Publishing Group DOI: 10.1038/s41589-020-0575-0 Structure of the O‐Antigen and the Lipid A from the Lipopolysaccharide of Fusobacterium nucleatum ATCC 51191 Autores: Pilar Garcia‐Vello, Flaviana Di Lorenzo, Dimitra Lamprinaki, Anna Notaro, Immacolata Speciale, Antonio Molinaro, Nathalie Juge, Cristina De Castro Publicado en: ChemBioChem, Issue 22/7, 2021, Page(s) 1252-1260, ISSN 1439-4227 Editor: John Wiley & Sons Ltd. DOI: 10.1002/cbic.202000751 The Escherichia coli Outer Membrane β-Barrel Assembly Machinery (BAM) Anchors the Peptidoglycan Layer by Spanning It with All Subunits Autores: Elisa Consoli, Jean-François Collet, Tanneke den Blaauwen Publicado en: International Journal of Molecular Sciences, Issue 22/4, 2021, Page(s) 1853, ISSN 1422-0067 Editor: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/ijms22041853 Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain Autores: Marianna Iorio, Sahar Davatgarbenam, Stefania Serina, Paolo Criscenzo, Mitja M. Zdouc, Matteo Simone, Sonia I. Maffioli, Richard H. Ebright, Stefano Donadio, Margherita Sosio Publicado en: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322 Editor: Nature Publishing Group DOI: 10.1038/s41598-021-84833-2 Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant Acinetobacter baumannii Clinical Isolates Autores: Vincent Trebosc, Sarah Gartenmann, Marcus Tötzl, Valentina Lucchini, Birgit Schellhorn, Michel Pieren, Sergio Lociuro, Marc Gitzinger, Marcel Tigges, Dirk Bumann, Christian Kemmer Publicado en: mBio, Issue 10/4, 2019, ISSN 2150-7511 Editor: American Society for Microbiology DOI: 10.1128/mbio.01083-19 MreC and MreD balance the interaction between the elongasome proteins PBP2 and RodA Autores: Xiaolong Liu, Jacob Biboy, Elisa Consoli, Waldemar Vollmer, Tanneke den Blaauwen Publicado en: Plos Genetics, Issue 16(12), 2020, Page(s) e1009276, ISSN 1553-7390 Editor: Public Library of Science DOI: 10.1371/journal.pgen.1009276 Fat Matters for Bugs: How Lipids and Lipid Modifications Make the Difference in Bacterial Life Autores: Paola Sperandeo, Alessandra Polissi, Emma De Fabiani Publicado en: European Journal of Lipid Science and Technology, Issue 121/10, 2019, Page(s) 1900204, ISSN 1438-7697 Editor: Wiley - V C H Verlag GmbbH & Co. DOI: 10.1002/ejlt.201900204 Mutation and Suppressor Analysis of the Essential Lipopolysaccharide Transport Protein LptA Reveals Strategies To Overcome Severe Outer Membrane Permeability Defects in Escherichia coli Autores: Federica A. Falchi, Elisa A. Maccagni, Simone Puccio, Clelia Peano, Cristina De Castro, Angelo Palmigiano, Domenico Garozzo, Alessandra M. Martorana, Alessandra Polissi, Gianni Dehò, Paola Sperandeo Publicado en: Journal of Bacteriology, Issue 200/2, 2018, ISSN 0021-9193 Editor: American Society for Microbiology DOI: 10.1128/jb.00487-17 Other (3) Structure-function analyses of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation Autores: J. A. Bryant, F. C. Morris, T. J. Knowles, R. Maderbocus, E. Heinz, G. Boelter, D. Alodaini, A. Colyer, P. J. Wotherspoon, K. A. Staunton, M. Jeeves, D. F. Browning, Y. R. Sevastsyanovich, T. J. Wells, A. E. Rossiter, V. N. Bavro, P. Sridhar, D. G. Ward, Z-S. Chong, C. Icke, A. Teo, S-S. Chng, View ORCID ProfileD. I. Roper, T. Lithgow, A. F. Cunningham, M. Banzhaf, M. Overduin, I. R. Henderson Publicado en: BioRxiv, 2020 Editor: BioRxiv DOI: 10.1101/2020.08.10.244616 Disorder is a critical component of lipoprotein sorting in Gram-negative bacteria Autores: Jessica El Rayes, Joanna Szewczyk, Michael Deghelt, André Matagne, Bogdan I. Iorga, Seung-Hyun Cho, Jean-François Collet Publicado en: BioRxiv, 2021 Editor: BioRxiv DOI: 10.1101/2021.01.05.425367 Metabolomic investigation of the pseudouridimycin producer, a prolific streptomycete Autores: Iorio, M., Davatgarbenam, S., Serina, S., Criscenzo, P., Zdouc, M.M., Simone, M., Maffioli, S.I., Ebright, R.H., Donadio, S. and Sosio, M. Publicado en: BioRxiv, Issue 5. November 2020, 2020 Editor: BioRxiv DOI: 10.1101/2020.11.05.369249 Thesis and dissertations (1) Antibiotic drug development Autores: Matias, C. S. S., Sommer, M. O. A., Ingmer, H., Weber, T., Polissi, A., & Olsen, J. E. Publicado en: 2020 Editor: Technical University of Denmark Buscando datos de OpenAIRE... Se ha producido un error en la búsqueda de datos de OpenAIRE No hay resultados disponibles
