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Smart capture phases for proteomics, glycomics and biomarker assays


Project website published and accessible

Project website published and accessible

Produce a minimum of two press releases

Produce a minimum of two press releases

Produce a project poster and a presentation

Produce a project poster and a presentation

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Magnetic Synthetic Receptors for Selective Clean-Up in Protein Biomarker Quantification

Author(s): Nicholas McKitterick, Frida Braathen, Magdalena A. Switnicka-Plak, Peter A. G. Cormack, Léon Reubsaet, Trine Grønhaug Halvorsen
Published in: Journal of Proteome Research, 19/8, 2020, Page(s) 3573-3582, ISSN 1535-3893
Publisher: American Chemical Society
DOI: 10.1021/acs.jproteome.0c00258

Oxoanion Imprinting Combining Cationic and Urea Binding Groups: A Potent Glyphosate Adsorber

Author(s): Sudhirkumar Shinde, Mona Mansour, Liliia Mavliutova, Anil Incel, Celina Wierzbicka, Hussein I. Abdel-Shafy, and Börje Sellergren
Published in: ACS Omega, 2021, ISSN 2470-1343
Publisher: American Chemical Society
DOI: 10.1021/acsomega.1c05079

Urea-based imprinted polymer hosts with switchable anion preference

Author(s): Sudhirkumar Shinde; Sudhirkumar Shinde; Anıl İncel; Mona Mansour; Gustaf D. Olsson; Ian A. Nicholls; Cem Esen; Javier Urraca; Börje Sellergren; Börje Sellergren
Published in: Journal of the American Chemical Society, 142(26), 2020, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c00707

Improved Solvothermal Synthesis of γ-Fe2O3 Magnetic Nanoparticles for SiO2 Coating

Author(s): Rashmi Mahajan; Subramanian Suriyanarayanan; Ian A. Nicholls
Published in: Nanomaterials, 11(8), 2021, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano11081889

Affinity capture in bottom-up protein analysis –overview of current status of proteolytic peptide capture using antibodies and molecularly imprinted polymers

Author(s): Halvorsen TG, McKitterick N, Kish, M.; Reubsaet, L.
Published in: Anal. Chim. Acta, 1182, 2021, ISSN 0003-2670
Publisher: Elsevier BV
DOI: 10.1016/j.aca.2021.338714

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells.

Author(s): Weihua Tian, Zilu Ye, Shengjun Wang, Morten Alder Schulz, Julie Van Coillie, Lingbo Sun, Yen-Hsi Chen, Yoshiki Narimatsu, Lars Hansen, Claus Kristensen, Ulla Mandel, Eric Paul Bennett, Siamak Jabbarzadeh-Tabrizi, Raphael Schiffmann, Jin-Song Shen, Sergey Y. Vakhrushev, Henrik Clausen & Zhang Yang
Published in: Nature Communications, 10, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-09809-3

Strategies for Molecular Imprinting and the Evolution of MIP Nanoparticles as Plastic Antibodies—Synthesis and Applications

Author(s): Refaat, D.; Aggour, M. G.; Farghali, A. A.; Mahajan, R.; Wiklander, J. G.; Nicholls, I. A.; Piletsky, S. A.
Published in: Int. Journal of Molecular Sciences, 20(24), 2019, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20246304

Selective Enrichment of Histidine Phosphorylated Peptides Using Molecularly Imprinted Polymers

Author(s): Anıl Incel, Ignacio Arribas Díez, Celina Wierzbicka, Katarzyna Gajoch, Ole N. Jensen, Börje Sellergren
Published in: Analytical Chemistry, 2021, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.0c04474

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

Author(s): Narimatsu, Yoshiki; Joshi, Hiren J.; Nason, Rebecca; Van Coillie, Julie; Karlsson, Richard; Sun, Lingbo; Ye, Zilu; Chen, Yen-Hsi; Schjoldager, Katrine T.; Steentoft, Catharina; Furukawa, Sanae; Bensing, Barbara A.; Sullam, Paul M.; Thompson, Andrew J.; Paulson, James C.; Büll, Christian; Adema, Gosse J.; Mandel, Ulla; Hansen, Lars; Bennett, Eric Paul; Varki, Ajit; Vakhrushev, Sergey Y.; Yang, Zha
Published in: Mol Cell, 75(2), 2019, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.05.017

Zirconium(IV)-IMAC Revisited: Improved Performance and Phosphoproteome Coverage by Magnetic Microparticles for Phosphopeptide Affinity Enrichment

Author(s): Ignacio Arribas Diez, Ireshyn Govender, Previn Naicker, Stoyan Stoychev, Justin Jordaan, Ole N. Jensen
Published in: J. Proteome Research, 20, 2021, ISSN 1535-3893
Publisher: American Chemical Society
DOI: 10.1021/acs.jproteome.0c00508

The Use of Computational Methods for the Development of Molecularly Imprinted Polymers

Author(s): Ian A. Nicholls; Kerstin Golker; Gustaf D. Olsson; Subramanian Suriyanarayanan; Jesper G. Wiklander
Published in: Polymers, Vol 13, Iss 2841, p 2841 (2021), 1, 2021, ISSN 2073-4360
Publisher: MDPI
DOI: 10.3390/polym13172841

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

Author(s): Narimatsu Y, Joshi HJ, Schjoldager KT, Hintze J, Halim A, Steentoft C, Nason R, Mandel U, Bennett EP, Clausen H, Vakhrushev SY
Published in: Mol. Cell Proteomics, 18(7), 2019, ISSN 1535-9476
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/mcp.ra118.001121

High salt compatible oxyanion receptors by dual ion imprinting

Author(s): Sudhirkumar Shinde; Mona Mansour; Anıl İncel; Liliia Mavliutova; Celina Wierzbicka; Börje Sellergren
Published in: Chemical Science, 11 (16), 2020, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9sc06508c

Combinatorial design of a sialic acid imprinted binding site exploring a dual ion receptor approach

Author(s): Liliia Mavliutova; Elena Verduci; Börje Sellergren
Published in: RSC Advances, 11, 2021, Page(s) 34329-34337, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1ra06962d

Mesoporous polymeric microspheres with high affinity for phosphorylated biomolecules

Author(s): Sudhirkumar Shinde, Jayashree Selvalatchmanan, Anil Incel, Maedeh Akhoundian, Anne K. Bendt, Federico Torta
Published in: New Journal of Chemistry, 42/11, 2018, Page(s) 8603-8608, ISSN 1144-0546
Publisher: Royal Society of Chemistry
DOI: 10.1039/C8NJ01114A

Highly efficient synthesis and assay of protein imprinted nanogels using magnetic templates

Author(s): Rashmi Mahajan, Mona Rouhi, Sudhirkumar Shinde, Thomas Bedwell, Anil Incel, Liliia Mavliutova, Sergey Piletsky, Ian Nicholls, Börje K-E Sellergren
Published in: Angewandte Chemie International Edition, 2018, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201805772

Selective detection of phospholipids using molecularly imprinted fluorescent sensory core-shell particles.

Author(s): Qianjin Li, Sudhirkumar Shinde, Giuliana Grasso, Antonio Caroli, Rahma Abouhany, Michele Lanzillotta, Guoqing Pan, Wei Wan, Knut Rurack & Börje Sellergren
Published in: Nature Scientific Report, 10, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-66802-3

Facilitating serum determination of neuron specific enolase at clinically relevant levels by coupling on-line molecularly imprinted solid-phase extraction to LC-MS/MS

Author(s): Nicholas McKitterick, Tugrul Cem Bicak, Peter A. G. Cormack, Léon Reubsaet, and Trine Grønhaug Halvorsen
Published in: Anal. Chim. Acta, 1140, 2020, ISSN 0003-2670
Publisher: Elsevier BV
DOI: 10.1016/j.aca.2020.10.022

Engineering mammalian cells to produce plant-specific N-glycosylation on proteins

Author(s): Joachim Steen Larsen; Richard Karlsson; Weihua Tian; Morten Alder Schulz; Annemarie Matthes; Henrik Clausen; Bent Larsen Petersen; Zhang Yang
Published in: Glycobiology, 1, 2020, ISSN 0959-6658
Publisher: Oxford University Press
DOI: 10.1093/glycob/cwaa009

Probing the binding specificities of human Siglecs by cell-based glycan arrays

Author(s): Christian Büll; Rebecca Nason; Lingbo Sun; Julie Van Coillie; Daniel Madriz Sørensen; Sam J. Moons; Zhang Yang; Steven Arbitman; Steve M. Fernandes; Sanae Furukawa; Ryan McBride; Corwin M. Nycholat; Gosse J. Adema; James C. Paulson; Ronald L. Schnaar; Thomas J. Boltje; Henrik Clausen; Yoshiki Narimatsu
Published in: Proc Natl Acad Sci U S A, 118(17), 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2026102118

On-line duplex molecularly imprinted solid-phase extraction for analysis of low-abundant biomarkers in human serum by liquid chromatography-tandem mass spectrometry

Author(s): McKitterick, N.; Bicak, T. C.; Switnicka-Plak, M. A.; Cormack, P. A. G.; Reubsaet, L.; Halvorsen, T. G.
Published in: J. Chromatogr. A, 1655, 2021, ISSN 0021-9673
Publisher: Elsevier BV
DOI: 10.1016/j.chroma.2021.462490

Discrimination between sialic acid linkage modes using sialyllactose-imprinted polymers

Author(s): Liliia Mavliutova; Bruna Munoz Aldeguer; Jesper Wiklander; Celina Wierzbicka; Chau Minh Huynh; Ian A. Nicholls; Knut Irgum; Börje Sellergren
Published in: RSC Advances, 11, 2021, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1ra02274a

Display of the human mucinome with defined O-glycans by gene engineered cells

Author(s): Nason R, Büll C, KonstantinidiA, SunL, Ye Z, HalimA, Wenjuan Du, SørensenD, FurukawaS, MandelU, JoshiH, DworkinL, HansenL, DavidL, IversonR, BensingB, SullamP, VarkiA, de VrieE, de HaanC, VincentelliR, HenrissatB, VakhrushevS, ClausenH, Narimatsu
Published in: Nature Communications, 12, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24366-4

Plastantikroppar som hittar cancerceller

Published in: Vetenskap och Hälsa, 2019
Publisher: Lund University

Zirconium(IV)-IMAC for phosphopeptide enrichment in phosphoproteomics

Author(s): IA Diez; Ireshyn S Govender; Previn Naicker; Stoyan Stoychev; Justin Jordaan; Ole Noerregaard Jensen
Published in: bioRxiv, 2020
Publisher: CSHL
DOI: 10.1101/2020.04.13.038810

Molecularly Imprinted Polymers for characterization of rare phosphorylation events

Author(s): Arribas Díez, Ignacio
Published in: Arribas Díez , I , Anil Incel & Chau Huynh 2019 , ' Molecularly Imprinted Polymers for characterization of rare phosphorylation events ' , Proteomics in Cell Biology and Disease Mechanisms , Heidelberg , Germany , 07/03/2019 - 09/03/2019 ., 1, 2019
Publisher: EMBL

Molecularly imprinted polymers for small cell lung cancer diagnosis

Author(s): Bicak,Tugrul Cem
Published in: 2021
Publisher: University of Strathclyde
DOI: 10.48730/0eyc-aj60

Amino acid sequence and side chain specific synthetic receptors targeting protein phosphorylation

Author(s): Anil Incel
Published in: Malmö University, 2021, ISBN 9789178772070
Publisher: Malmö University
DOI: 10.24834/isbn.9789178772087