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Harnessing the power of enzymatic oxygen activation

Description du projet

Une nouvelle cohorte de chercheurs s’apprête à libérer la puissance des oxygénases

L’oxygénation, c’est-à-dire l’incorporation d’oxygène dans les molécules, est un processus clé dans de nombreuses réactions métaboliques. La nature y parvient grâce aux oxygénases, des enzymes qui catalysent l’oxydation d’une grande variété de molécules organiques par l’oxygène moléculaire. La polyvalence de ces enzymes et l’importance des réactions et des produits font de la production et de l’application des oxygénases un objectif clé de la biotechnologie. Cependant, leur application à grande échelle constitue un véritable défi. Avec le soutien du programme Actions Marie Skłodowska-Curie, le projet OXYTRAIN créera un réseau européen de formation composé de partenaires universitaires et non universitaires afin d’encourager une nouvelle génération de chercheurs talentueux et expérimentés à relever le défi.

Objectif

For the selective and effective incorporation of oxygen into biological molecules (oxygenation reaction), several enzyme types have evolved in nature. They catalyse crucial reactions in various metabolic routes. The chemistry feasible with these biocatalysts is unrivalled when compared with conventional chemical methods. Therefore, these oxygenating enzymes are very promising tools in biotechnological approaches. However, when compared with other enzyme classes, such as hydrolases, oxygenases are still in their infancy considering their biotechnological potential. To fully exploit the catalytic power of oxygenases, several hurdles have to be taken for which a higher level of knowledge on these enzymes is needed while also technical aspects have to be solved.

The European Training Network (ETN) OXYTRAIN is a joint academic/non-academic training initiative supporting the convergence of biochemistry, enzyme engineering and biotechnology. The consortium's mutual goal is developing a new generation of innovative and entrepreneurial early stage researchers (ESRs) to satisfy the need for knowledge and skills to produce and apply oxidative enzymes. This will be achieved by setting up a network and intersectoral programme in which multiple disciplines will be integrated and exploited. By bringing together 7 academic beneficiaries that are experts in the field of individual oxygenase groups, the network will provide perfect conditions for cross-fertilization of knowledge, while the 3 industrial beneficiaries and 5 partner organisations will add to the consortium by translating the generated knowledge into real industrial applications, such as textiles, pharmaceuticals and biorefineries.

Coordinateur

RIJKSUNIVERSITEIT GRONINGEN
Contribution nette de l'UE
€ 922 184,90
Adresse
Broerstraat 5
9712CP Groningen
Pays-Bas

Voir sur la carte

Région
Noord-Nederland Groningen Overig Groningen
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
€ 922 184,90

Participants (9)

Partenaires (5)