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Harnessing the power of enzymatic oxygen activation

Projektbeschreibung

Neue Forschungsgruppe entfesselt bald die Kraft der Oxygenasen

Die Oxygenierung, bei der Sauerstoff in Moleküle eingebaut wird, stellt einen Schlüsselprozess vieler Stoffwechselreaktionen dar. In der Natur geschieht dies durch sogenannte Oxygenasen, Enzyme, die die Oxidation einer Vielzahl von organischen Molekülen durch molekularen Sauerstoff katalysieren. Die Vielseitigkeit dieser Enzyme und die Bedeutung der Reaktionen und Produkte lassen die Herstellung und Anwendung von Oxygenasen zu einem wichtigen Ziel der Biotechnologie werden. Ihr großmaßstäblicher Einsatz ist jedoch eine große Herausforderung. Das Ziel des im Rahmen der Marie-Skłodowska-Curie-Maßnahmen unterstützten Projekts OXYTRAIN ist die Schaffung eines europäischen Ausbildungsnetzes aus akademischen und nichtakademischen Partnern, um eine neue Generation talentierter und erfahrener Forschender zu fördern, die sich dieser Herausforderung stellen.

Ziel

For the selective and effective incorporation of oxygen into biological molecules (oxygenation reaction), several enzyme types have evolved in nature. They catalyse crucial reactions in various metabolic routes. The chemistry feasible with these biocatalysts is unrivalled when compared with conventional chemical methods. Therefore, these oxygenating enzymes are very promising tools in biotechnological approaches. However, when compared with other enzyme classes, such as hydrolases, oxygenases are still in their infancy considering their biotechnological potential. To fully exploit the catalytic power of oxygenases, several hurdles have to be taken for which a higher level of knowledge on these enzymes is needed while also technical aspects have to be solved.

The European Training Network (ETN) OXYTRAIN is a joint academic/non-academic training initiative supporting the convergence of biochemistry, enzyme engineering and biotechnology. The consortium's mutual goal is developing a new generation of innovative and entrepreneurial early stage researchers (ESRs) to satisfy the need for knowledge and skills to produce and apply oxidative enzymes. This will be achieved by setting up a network and intersectoral programme in which multiple disciplines will be integrated and exploited. By bringing together 7 academic beneficiaries that are experts in the field of individual oxygenase groups, the network will provide perfect conditions for cross-fertilization of knowledge, while the 3 industrial beneficiaries and 5 partner organisations will add to the consortium by translating the generated knowledge into real industrial applications, such as textiles, pharmaceuticals and biorefineries.

Koordinator

RIJKSUNIVERSITEIT GRONINGEN
Netto-EU-Beitrag
€ 922 184,90
Adresse
Broerstraat 5
9712CP Groningen
Niederlande

Auf der Karte ansehen

Region
Noord-Nederland Groningen Overig Groningen
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 922 184,90

Beteiligte (9)

Partner (5)