Descripción del proyecto
Una nueva cohorte de investigadores se prepara para liberar el poder de las oxigenasas
La oxigenación, la incorporación de oxígeno a las moléculas, es un proceso fundamental en muchas reacciones metabólicas. La naturaleza lo consigue con las llamadas oxigenasas, enzimas que catalizan la oxidación de una enorme variedad de moléculas orgánicas por el oxígeno molecular. La versatilidad de estas enzimas y la importancia de las reacciones y productos hacen de la producción y aplicación de oxigenasas un objetivo principal en el ámbito de la biotecnología. Sin embargo, su aplicación a gran escala supone un reto considerable. El equipo del proyecto OXYTRAIN, que cuenta con el apoyo de las Acciones Marie Skłodowska-Curie, creará una red europea de formación compuesta por socios de dentro y fuera del mundo universitario y científico para fomentar una nueva generación de investigadores con talento y experiencia que acepten el reto.
Objetivo
For the selective and effective incorporation of oxygen into biological molecules (oxygenation reaction), several enzyme types have evolved in nature. They catalyse crucial reactions in various metabolic routes. The chemistry feasible with these biocatalysts is unrivalled when compared with conventional chemical methods. Therefore, these oxygenating enzymes are very promising tools in biotechnological approaches. However, when compared with other enzyme classes, such as hydrolases, oxygenases are still in their infancy considering their biotechnological potential. To fully exploit the catalytic power of oxygenases, several hurdles have to be taken for which a higher level of knowledge on these enzymes is needed while also technical aspects have to be solved.
The European Training Network (ETN) OXYTRAIN is a joint academic/non-academic training initiative supporting the convergence of biochemistry, enzyme engineering and biotechnology. The consortium's mutual goal is developing a new generation of innovative and entrepreneurial early stage researchers (ESRs) to satisfy the need for knowledge and skills to produce and apply oxidative enzymes. This will be achieved by setting up a network and intersectoral programme in which multiple disciplines will be integrated and exploited. By bringing together 7 academic beneficiaries that are experts in the field of individual oxygenase groups, the network will provide perfect conditions for cross-fertilization of knowledge, while the 3 industrial beneficiaries and 5 partner organisations will add to the consortium by translating the generated knowledge into real industrial applications, such as textiles, pharmaceuticals and biorefineries.
Ámbito científico
Programa(s)
Régimen de financiación
MSCA-ITN-ETN - European Training NetworksCoordinador
9712CP Groningen
Países Bajos