Descrizione del progetto
Una nuova coorte di ricercatori si prepara a liberare il potere delle ossigenasi
L’ossigenazione, ossia l’incorporazione dell’ossigeno nelle molecole, è un processo centrale in molte reazioni metaboliche. La natura ci riesce con le cosiddette ossigenasi, enzimi che catalizzano l’ossidazione di un’enorme varietà di molecole organiche da parte dell’ossigeno molecolare. La versatilità di questi enzimi e l’importanza di reazioni e prodotti rendono la produzione e l’applicazione delle ossigenasi un obiettivo centrale nelle biotecnologie. Tuttavia, la loro applicazione su larga scala è sensibilmente impegnativa. Con il sostegno del programma di azioni Marie Skłodowska-Curie, il progetto OXYTRAIN creerà una rete europea di formazione composta da partner accademici e non accademici per promuovere una nuova generazione di ricercatori esperti e di talento che raccolga la sfida.
Obiettivo
For the selective and effective incorporation of oxygen into biological molecules (oxygenation reaction), several enzyme types have evolved in nature. They catalyse crucial reactions in various metabolic routes. The chemistry feasible with these biocatalysts is unrivalled when compared with conventional chemical methods. Therefore, these oxygenating enzymes are very promising tools in biotechnological approaches. However, when compared with other enzyme classes, such as hydrolases, oxygenases are still in their infancy considering their biotechnological potential. To fully exploit the catalytic power of oxygenases, several hurdles have to be taken for which a higher level of knowledge on these enzymes is needed while also technical aspects have to be solved.
The European Training Network (ETN) OXYTRAIN is a joint academic/non-academic training initiative supporting the convergence of biochemistry, enzyme engineering and biotechnology. The consortium's mutual goal is developing a new generation of innovative and entrepreneurial early stage researchers (ESRs) to satisfy the need for knowledge and skills to produce and apply oxidative enzymes. This will be achieved by setting up a network and intersectoral programme in which multiple disciplines will be integrated and exploited. By bringing together 7 academic beneficiaries that are experts in the field of individual oxygenase groups, the network will provide perfect conditions for cross-fertilization of knowledge, while the 3 industrial beneficiaries and 5 partner organisations will add to the consortium by translating the generated knowledge into real industrial applications, such as textiles, pharmaceuticals and biorefineries.
Campo scientifico
Programma(i)
Argomento(i)
Meccanismo di finanziamento
MSCA-ITN-ETN - European Training NetworksCoordinatore
9712CP Groningen
Paesi Bassi