Individualizing statin therapy by using a systems pharmacology decision support algorithm

Pubblicazioni

Functional in vitro characterization of SLCO1B1 variants and simulation of the clinical pharmacokinetic impact of impaired OATP1B1 function

Autori: Wilma Kiander, Noora Sjöstedt, Riikka Manninen, Liina Jaakkonen, Kati-Sisko Vellonen, Mikko Neuvonen, Mikko Niemi, Seppo Auriola, Heidi Kidron
Pubblicato in: European Journal of Pharmaceutical Sciences, Numero 176, 2022, Pagina/e 106246, ISSN 0928-0987
Editore: Elsevier BV
DOI: 10.1016/j.ejps.2022.106246

Comparative Hepatic and Intestinal Metabolism and Pharmacodynamics of Statins

Autori: Anne M. Filppula, Päivi Hirvensalo, Heli Parviainen, Vilma E. Ivaska, K. Ivar Lönnberg, Feng Deng, Jenni Viinamäki, Mika Kurkela, Mikko Neuvonen and Mikko Niemi
Pubblicato in: Drug Metabolism and Disposition, 2021, ISSN 0090-9556
Editore: American Society for Pharmacology and Experimental Therapeutics
DOI: 10.1124/dmd.121.000406

Comparative Hepatic and Intestinal Efflux Transport of Statins

Autori: Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi
Pubblicato in: Drug Metabolism and Disposition, 2021, ISSN 0090-9556
Editore: American Society for Pharmacology and Experimental Therapeutics
DOI: 10.1124/dmd.121.000430

The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1, ABCG2, and CYP2C9 genotypes and Statin-Associated Musculoskeletal Symptoms

Autori: Rhonda M. Cooper-DeHoff,Mikko Niemi,Laura B. Ramsey,Jasmine A. Luzum,E. Katriina Tarkiainen,Robert J. Straka,Li Gong,Sony Tuteja,Russell A. Wilke,Mia Wadelius,Eric A. Larson,Dan M. Roden,Teri E. Klein,Sook Wah Yee,Ronald M. Krauss,Richard M. Turner,Latha Palaniappan,Andrea Gaedigk,Kathleen M. Giacomini,Kelly E. Caudle,Deepak Voora
Pubblicato in: Clinical Pharmacology & Therapeutics, 2022, ISSN 1532-6535
Editore: The American Society for Clinical Pharmacology and Therapeutics
DOI: 10.1002/cpt.2557

Rhabdomyolysis during concomitant ticagrelor and rosuvastatin: A breast cancer resistance protein‐mediated drug interaction?

Autori: Minna Lehtisalo; Wilma Kiander; Anne M. Filppula; Feng Deng; Heidi Kidron; Mari Korhonen; Johanna Sinkko; Kimmo Koivula; Mikko Niemi
Pubblicato in: British Journal of Clinical Pharmacology, 2023, Pagina/e 2309-2315, ISSN 0306-5251
Editore: Blackwell Publishing Inc.
DOI: 10.1111/bcp.15684

Functional Characterization of Six <i>SLCO1B1</i> (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder

Autori: Katja Häkkinen; Wilma Kiander; Heidi Kidron; Markku Lähteenvuo; Lea Urpa; Jonne Lintunen; Kati-Sisko Vellonen; Seppo Auriola; Minna Holm; Kaisla Lahdensuo; Olli Kampman; Erkki Isometsä; Tuula Kieseppä; Jouko Lönnqvist; Jaana Suvisaari; Jarmo Hietala; Jari Tiihonen; Aarno Palotie; Ari V. Ahola-Olli; Mikko Niemi
Pubblicato in: Molecular Pharmaceutics, 2023, ISSN 1543-8384
Editore: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.2c00715

Clinical Studies on Drug–Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation

Autori: Aleksi Tornio; Anne M. Filppula; Mikko Niemi; Janne T. Backman
Pubblicato in: Clinical Pharmacology and Therapeutics, 2019, Pagina/e 1345-1361, ISSN 0009-9236
Editore: Nature Publishing Group
DOI: 10.1002/cpt.1435

Real-world pharmacogenetics of statin intolerance: effects of SLCO1B1, ABCG2, and CYP2C9 variants

Autori: K. Ivar Lönnberg, Aleksi Tornio, Päivi Hirvensalo, Jenni Keskitalo, Anna-Liina Mustaniemi, Johanna I. Kiiski, Anne M. Filppula, Mikko Niemi
Pubblicato in: Pharmacogenetics and Genomics, 2023, ISSN 1744-6872
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/fpc.0000000000000504

È in corso la ricerca di dati su OpenAIRE...

Pubblicazioni

Condividi questa pagina

Scarica