SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine

Informazioni relative al progetto

SPIDIA4P

ID dell’accordo di sovvenzione: 733112

DOI

10.3030/733112

Progetto chiuso

Data della firma CE 30 Novembre 2016

Data di avvio 1 Gennaio 2017

Data di completamento 30 Giugno 2021

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 2 079 053,75

Contributo UE

€ 1 999 972,50

Coordinato da

QIAGEN GMBH
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (9)

List of standards available
Definition of the communication campaign and reviewed (M24)

Definition of the communication campaign and reviewed once a year

Summary of the validation studies for demonstrating a reduction of diagnostic mistake
List of reference biobanks providing biological resources complying with the standards
Education and training curriculum
Definition of the communication campaign and reviewed (M36)

Definition of the communication campaign and reviewed once a year

Definition of the communication campaign and reviewed (M54)

Definition of the communication campaign and reviewed once a year

Definition of the communication campaign and reviewed (M12)

Definition of the communication campaign and reviewed once a year ( M12, M24, M36, M48)

Statistics, summary of incidents and measures taken published in the public domain (M18)

Statistics, summary of incidents and measures taken published in the public domain and any updated figures will be included in the periodic reports (M36 and M48)

Websites, patent fillings, videos etc. (6)

Newsletter of SPIDIA4P (M24)

Newsletter of SPIDIA4P

Newsletter of SPIDIA4P (M54)

Newsletter of SPIDIA4P

Newsletter of SPIDIA4P (M36)

Newsletter of SPIDIA4P

Final conference agenda
Newsletter of SPIDIA4P (M12)

Newsletter of SPIDIA4P (M12, M24, M36, M48)

Sub section for SPIDIA4P established on the SPIDIA website

Pubblicazioni

Peer reviewed articles (18)

A Novel HPLC-Based Method to Investigate on RNA after Fixation

Autori: Paolo Fattorini, Cristina Forzato, Domenico Tierno, Eleonora De Martino, Eros Azzalini, Vincenzo Canzonieri, Giorgio Stanta, Serena Bonin
Pubblicato in: International Journal of Molecular Sciences, Numero 21/20, 2020, Pagina/e 7540, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207540

Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows

Autori: Rita Lampignano, Martin H.D Neumann, Sabrina Weber, Vera Kloten, Andrei Herdean, Thorsten Voss, Daniel Groelz, Anna Babayan, Marco Tibbesma, Martin Schlumpberger, Francesca Chemi, Dominic G Rothwell, Harriet Wikman, Jean-Pierre Galizzi, Inger Riise Bergheim, Hege Russnes, Benedetta Mussolin, Serena Bonin, Christine Voigt, Hanny Musa, Pamela Pinzani, Evi Lianidou, Ged Brady, Michael R Speicher, Kla
Pubblicato in: Clinical Chemistry, Numero 66/1, 2019, Pagina/e 149-160, ISSN 0009-9147
Editore: American Association for Clinical Chemistry, Inc.
DOI: 10.1373/clinchem.2019.306837

Standardization of generic pre-analytical procedures for in vitro diagnostics for personalized medicine

Autori: Uwe Oelmueller
Pubblicato in: New Biotechnology, Numero 60, 2021, Pagina/e 1, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2020.07.003

Metabolomic Fingerprints in Large Population Cohorts: Impact of Preanalytical Heterogeneity

Autori: Veronica Ghini, Peter M Abuja, Ozren Polasek, Lukasz Kozera, Päivi Laiho, Gabriele Anton, Marie Zins, Janis Klovins, Andres Metspalu, H -Erich Wichmann, Christian Gieger, Claudio Luchinat, Kurt Zatloukal, Paola Turano
Pubblicato in: Clinical Chemistry, 2021, ISSN 0009-9147
Editore: American Association for Clinical Chemistry, Inc.
DOI: 10.1093/clinchem/hvab092

The pre-analytical phase of the liquid biopsy

Autori: Francesca Salvianti, Stefania Gelmini, Filomena Costanza, Irene Mancini, Gemma Sonnati, Lisa Simi, Mario Pazzagli, Pamela Pinzani
Pubblicato in: New Biotechnology, Numero 55, 2020, Pagina/e 19-29, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.09.006

Impact of storage conditions on the quality of nucleic acids in paraffin embedded tissues

Autori: Daniel Groelz, Christian Viertler, Daniela Pabst, Nadine Dettmann, Kurt Zatloukal
Pubblicato in: PLOS ONE, Numero 13/9, 2018, Pagina/e e0203608, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0203608

Biobanks in personalized medicine

Autori: Kurt Zatloukal, Cornelia Stumptner, Penelope Kungl, Heimo Mueller
Pubblicato in: Expert Review of Precision Medicine and Drug Development, Numero 3/4, 2018, Pagina/e 265-273, ISSN 2380-8993
Editore: Expert Review of Precision Medecine and Drug Development
DOI: 10.1080/23808993.2018.1493921

High-throughput metabolomics by 1D NMR

Autori: Alessia Vignoli, Veronica Ghini, Gaia Meoni, Cristina Licari, Panteleimon G. Takis, Leonardo Tenori, Paola Turano, Claudio Luchinat
Pubblicato in: Angewandte Chemie International Edition, Numero -, 2018, Pagina/e -, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201804736

Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14–16, 2018; Vienna, Austria

Autori: M. S. Lim, Thomas Beyer, A. Babayan, M. Bergmann, M. Brehme, A. Buyx, J. Czernin, G. Egger, K. S. J. Elenitoba-Johnson, B. Gückel, A. Jačan, H. Haslacher, R. J. Hicks, L. Kenner, M. Langanke, M. Mitterhauser, B. J. Pichler, H. R. Salih, R. Schibli, S. Schulz, J. Simecek, J. Simon, M. O. Soares, U. Stelzl, W. Wadsak, K. Zatloukal, M. Zeitlinger, M. Hacker
Pubblicato in: Molecular Imaging and Biology, Numero 22/1, 2020, Pagina/e 47-65, ISSN 1536-1632
Editore: Elsevier BV
DOI: 10.1007/s11307-019-01361-2

NMR for sample quality assessment in metabolomics

Autori: Veronica Ghini, Deborah Quaglio, Claudio Luchinat, Paola Turano
Pubblicato in: New Biotechnology, Numero 52, 2019, Pagina/e 25-34, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.04.004

Pre-analytics and tumor heterogeneity

Autori: Serena Bonin, Giorgio Stanta
Pubblicato in: New Biotechnology, Numero 55, 2020, Pagina/e 30-35, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.09.007

The impact of crosslinking and non-crosslinking fixatives on antigen retrieval and immunohistochemistry

Autori: Cornelia Stumptner, Daniela Pabst, Martina Loibner, Christian Viertler, Kurt Zatloukal
Pubblicato in: New Biotechnology, Numero 52, 2019, Pagina/e 69-83, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.05.003

Methodological and statistical issues in developing an External Quality Assessment scheme in laboratory medicine: Focus on biomarker research

Autori: Paolo Verderio, Sara Pizzamiglio, Chiara Maura Ciniselli
Pubblicato in: New Biotechnology, Numero 52, 2019, Pagina/e 54-59, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.05.001

Pre-analytical processes in medical diagnostics: New regulatory requirements and standards

Autori: Georges Dagher, Karl-Friedrich Becker, Serena Bonin, Carole Foy, Stefania Gelmini, Mikael Kubista, Penelope Kungl, Uwe Oelmueller, Helen Parkes, Pamela Pinzani, Peter Riegman, Ulrike Schröder, Cornelia Stumptner, Paola Turano, Robert Sjöback, Andrea Wutte, Kurt Zatloukal
Pubblicato in: New Biotechnology, Numero 52, 2019, Pagina/e 121-125, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.05.002

Tissues under-vacuum to overcome suboptimal preservation

Autori: Laura Annaratone, Caterina Marchiò, Anna Sapino
Pubblicato in: New Biotechnology, Numero 52, 2019, Pagina/e 104-109, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.05.007

How standardization of the pre-analytical phase of both research and diagnostic biomaterials can increase reproducibility of biomedical research and diagnostics

Autori: P.H.J. Riegman, K.F. Becker, K. Zatloukal, M. Pazzagli, U. Schröder, U. Oelmuller
Pubblicato in: New Biotechnology, Numero 53, 2019, Pagina/e 35-40, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2019.06.007

Biobanks for life sciences and personalized medicine: importance of standardization, biosafety, biosecurity, and data management

Autori: Heimo Müller, Georges Dagher, Martina Loibner, Cornelia Stumptner, Penelope Kungl, Kurt Zatloukal
Pubblicato in: Current Opinion in Biotechnology, Numero 65, 2020, Pagina/e 45-51, ISSN 0958-1669
Editore: Elsevier BV
DOI: 10.1016/j.copbio.2019.12.004

Cold Formalin Fixation Guarantees DNA Integrity in Formalin Fixed Paraffin Embedded Tissues: Premises for a Better Quality of Diagnostic and Experimental Pathology With a Specific Impact on Breast Cancer

Autori: Enrico Berrino, Laura Annaratone, Umberto Miglio, Elena Maldi, Chiara Piccinelli, Erica Peano, Davide Balmativola, Paola Cassoni, Alberto Pisacane, Ivana Sarotto, Tiziana Venesio, Anna Sapino, Caterina Marchiò
Pubblicato in: Frontiers in Oncology, Numero 10, 2020, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2020.00173

Book chapters (1)

Metabolomic Fingerprints in Large Population Cohorts: Impact of Preanalytical Heterogeneity

Autori: Ghini V, Abuja M P, Polasek O, Kozera L, Laiho P, Anton G, Zins M, Klovins J, Metspalu A, Wichmann H E, Gieger C, Luchinat C, Zatloukal K, Turano P
Pubblicato in: Oxford ACADEMIE, 2021
Editore: Chinical chemistry

Non-peer reviewed articles (1)

Antibody validation: a view from the mountains

Autori: Michael J. Taussig, Cláudia Fonseca, James S. Trimmer
Pubblicato in: New Biotechnology, Numero 45, 2018, Pagina/e 1-8, ISSN 1871-6784
Editore: Elsevier BV
DOI: 10.1016/j.nbt.2018.08.002