Optimizing response to Li treatment through personalized evaluation of individuals with bipolar I disorder: the R-LiNK initiative

Informazioni relative al progetto

R-LiNK

ID dell’accordo di sovvenzione: 754907

DOI

10.3030/754907

Progetto chiuso

Data della firma CE 21 Novembre 2017

Data di avvio 1 Gennaio 2018

Data di completamento 30 Giugno 2024

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 7 913 612,25

Contributo UE

€ 7 702 532,25

Coordinato da

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (6)

7Li MRI and primary outcome

7Li MRI and primary outcome : Manuscripts suitable for dissemination and presentation outlining the relationship between brain Li distribution and treatment response.

Report on status of posting results

Report on the status of posting results in the study registry/ies (including timelines when final posting of results is scheduled after end of funding period).

7Li MRI descriptive analysis

7Li MRI descriptive analysis : Manuscripts suitable for dissemination and presentation outlining the relationship between brain Li and baseline subject characteristics.

"Report on the ""enhanced adherence program"""

Report on (i) the feasibility and acceptability (patients view and clinicians view) of the “enhanced adherence program”, (ii) the global adherence of the recruited sample to be prepared once the follow-up evaluations are completed

Cost-effectiveness report

Based on the different predictive values of the different tests (biological (WP6), neuroimaging (WP4, WP5), multimodal (WP7)), KCL (P12) will simulate the added values in terms of cost-effectiveness of the implementation of these tests in the clinical practice.

Qualitative report Studies on acceptability-feasibility of the Lithium self-monitoring device (ALCYM, P10) and its potential to be transferred to bedside

P10 (Alcym) will report on the main characteristics of the Lithium self-monitoring device, its acceptability-feasibility and exploitation plan

Pubblicazioni

Peer reviewed articles (13)

Anxiety and depression played a central role in the COVID-19 mental distress: A network analysis

Autori: Fico G
Pubblicato in: Journal Of Affective Disorders, 2019, Pagina/e 384-392, ISSN 0165-0327
Editore: Elsevier BV
DOI: 10.1016/j.jad.2023.06.034

Can an Integrated Science Approach to Precision Medicine Research Improve Lithium Treatment in Bipolar Disorders?

Autori: Jan Scott, Bruno Etain, Frank Bellivier
Pubblicato in: Frontiers in Psychiatry, Numero 9, 2018, ISSN 1664-0640
Editore: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2018.00360

Duration of untreated illness and bipolar disorder: time for a new definition? Results from a cross-sectional study

Autori: Fico G
Pubblicato in: Journal Of Affective Disorders, 2017, Pagina/e 513-520, ISSN 0165-0327
Editore: Elsevier BV
DOI: 10.1016/j.jad.2021.07.062

Accumulation of Lithium in the Hippocampus of Patients With Bipolar Disorder: A Lithium-7 Magnetic Resonance Imaging Study at 7 Tesla

Autori: Jacques Stout, Franz Hozer, Arthur Coste, Franck Mauconduit, Nouzha Djebrani-Oussedik, Samuel Sarrazin, Joel Poupon, Manon Meyrel, Sandro Romanzetti, Bruno Etain, Cécile Rabrait-Lerman, Josselin Houenou, Frank Bellivier, Edouard Duchesnay, Fawzi Boumezbeur
Pubblicato in: Biological Psychiatry, Numero 88/5, 2020, Pagina/e 426-433, ISSN 0006-3223
Editore: Elsevier BV
DOI: 10.1016/j.biopsych.2020.02.1181

Patterns of pharmacotherapy for bipolar disorder: A GBC survey

Autori: Singh B
Pubblicato in: Bipolar Disorders, Numero 22-32, 2019, ISSN 1398-5647
Editore: Blackwell Publishing Inc.
DOI: 10.1111/bdi.13366

Long‐term treatment of bipolar disorder type I: A systematic and critical review of clinical guidelines with derived practice algorithms

Autori: Norma Verdolini, Diego Hidalgo‐Mazzei, Laura Del Matto, Michele Muscas, Isabella Pacchiarotti, Andrea Murru, Ludovic Samalin, Alberto Aedo, Mauricio Tohen, Heinz Grunze, Allan H. Young, André F. Carvalho, Eduard Vieta
Pubblicato in: Bipolar Disorders, 2020, ISSN 1398-5647
Editore: Blackwell Publishing Inc.
DOI: 10.1111/bdi.13040

Exploring the potential of representation and transfer learning for anatomical neuroimaging: Application to psychiatry

Autori: Dufumier, B.
Pubblicato in: NeuroImage, 2023, ISSN 1053-8119
Editore: Academic Press
DOI: 10.1016/j.neuroimage.2024.120665

Correlation between emotion dysregulation and mood symptoms of bipolar disorder: A systematic review and meta-analysis

Autori: Oliva V
Pubblicato in: Acta Psychiatrica Scandinavica, 2019, Pagina/e 472-490, ISSN 0001-690X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/acps.13618

Make lithium great again – Precisely!

Autori: Frank Bellivier, Allan H. Young, Jan Scott, Bruno Etain, David A. Cousins
Pubblicato in: Bipolar Disorders, Numero 23/2, 2021, Pagina/e 209-210, ISSN 1398-5647
Editore: Blackwell Publishing Inc.
DOI: 10.1111/bdi.13023

Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative

Autori: Jan Scott, Diego Hidalgo-Mazzei, Rebecca Strawbridge, Allan Young, Matthieu Resche-Rigon, Bruno Etain, Ole A. Andreassen, Michael Bauer, Djamila Bennabi, Andrew M. Blamire, Fawzi Boumezbeur, Paolo Brambilla, Nadia Cattane, Annamaria Cattaneo, Marie Chupin, Klara Coello, Yann Cointepas, Francesc Colom, David A. Cousins, Caroline Dubertret, Edouard Duchesnay, Adele Ferro, Aitana Garcia-Estela, Jose
Pubblicato in: International Journal of Bipolar Disorders, Numero 7/1, 2019, ISSN 2194-7511
Editore: SpringerOpen
DOI: 10.1186/s40345-019-0156-x

Separating common from salient patterns with Contrastive Representation Learning

Autori: Robin Louiset
Pubblicato in: HAL Telecom Paris, 2024, ISSN 2374-3468
Editore: HAL Telecom Paris
DOI: 10.48550/arXiv.2402.11928

An evidence map of actigraphy studies exploring longitudinal associations between rest-activity rhythms and course and outcome of bipolar disorders

Autori: Jan Scott, Francesc Colom, Allan Young, Frank Bellivier, Bruno Etain
Pubblicato in: International Journal of Bipolar Disorders, Numero 8/1, 2020, ISSN 2194-7511
Editore: SpringerOpen
DOI: 10.1186/s40345-020-00200-6

Is Usability Engineering Anticipation Possible during the Initial Research Actions? An Example with the R-Link in Vitro Self-monitoring Device

Autori: K. Charrière, C. Azzopardi, S. Pelayo, M. Nicolier, T. Lihoreau, F. Bellivier, E. Haffen and B. Wacogne
Pubblicato in: Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies - ClinMed, 2022, ISSN 2184-4356
Editore: SCITEPRESS - Science and Technology Publications
DOI: 10.5220/0010971600003123

Conference proceedings (2)

Functional Analysis to Drive Research and Identify Regulation Requirements: An Example with a Lithium Monitoring Device

Autori: K. Charrière, C. Azzopardi, M. Nicolier, T. Lihoreau, F. Bellivier, E. Haffen, B. Wacogne
Pubblicato in: Proceedings of the 14th International Joint Conference on Biomedical Engineering Systems and Technologies, 2021, Pagina/e 300-307, ISBN 978-989-758-490-9
Editore: SCITEPRESS - Science and Technology Publications
DOI: 10.5220/0010382503000307

Calibration Free and Fluorescein Based Fiber Optic pH Sensor for Clinical Applications

Autori: Bernard Gauthier-Manuel, Rutjaphan Kateklum, Bruno Wacogne
Pubblicato in: 2018 IEEE SENSORS, 2018, Pagina/e 1-4, ISBN 978-1-5386-4707-3
Editore: IEEE
DOI: 10.1109/icsens.2018.8630296

Non-peer reviewed articles (1)

Lithium: past, present, and future

Autori: David A Cousins, Letizia Squarcina, Fawzi Boumezbeur, Allan H Young, Frank Bellivier
Pubblicato in: The Lancet Psychiatry, Numero 7/3, 2020, Pagina/e 222-224, ISSN 2215-0366
Editore: Elsevier Limited
DOI: 10.1016/s2215-0366(19)30365-7