Obiettivo The world faces a growing epidemic of antimicrobial resistance (AMR); however, only two new classes of antibiotics have been brought to the market in the last 30 years. The discovery and development of new antibiotics is essential to maintain medical advances but poses significant scientific, clinical, and financial challenges, particularly for antibiotics active against Gram-negative bacteria (such as E. coli). Such bacteria have effective barriers against drugs, making treatment difficult, resistance likely and development costs and risks high. In addition, any new antibiotics brought to the market would likely be used cautiously to delay the development of resistance, adding an additional financial challenge in recouping the development costs. The O’Neill Report on AMR identifies diagnostics as critical to the battle against antibiotic resistance.This innovation action, BreathSpec, proposes a viable solution to the global problem of AMR through the final developmental stages of an existing diagnostic device, which will allow a rapid, binary decision to be made on the need for antibiotic treatment, and which with suitable optimisation will allow further differentiation and stratification to take place. The Innovation Action includes technical developments to optimise its function, data acquisition for the development of the decision making analytical function and clinical validation.It addresses these issues by producing reliable identification and quantification of key signature volatiles present in exhaled breath. It provides a non-invasive method for monitoring the volatile organic compounds present in an individual’s exhaled breath (and subsequently the blood) and has long been recognised as having significant utility as a clinical test that can be used for early disease detection and monitoring, and potentially to diagnose specific bacterial infections for better, more targeted use of existing antibiotics. Campo scientifico medical and health sciencesclinical medicinepneumologynatural scienceschemical sciencesorganic chemistryvolatile organic compoundsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsmedical and health sciencesbasic medicinepathologymedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance Programma(i) H2020-EC - Horizon 2020 Framework Programme Main Programme H2020-EU.3. - PRIORITY 'Societal challenges H2020-EU.2. - PRIORITY 'Industrial leadership' Argomento(i) FTIPilot-01-2016 - Fast Track to Innovation Pilot Invito a presentare proposte H2020-FTIPilot-2016 Vedi altri progetti per questo bando Bando secondario H2020-FTIPilot-2016-1 Meccanismo di finanziamento IA - Innovation action Coordinatore IMSPEX DIAGNOSTICS LIMITED Contribution nette de l'UE € 1 141 700,00 Indirizzo TY MENTER, NAVIGATION PARK, RCT CF45 4SN Abercynon Regno Unito Mostra sulla mappa PMI L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione. Sì Regione Wales West Wales and The Valleys Central Valleys Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Collegamenti Contatta l’organizzazione Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 1 631 500,00 Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo netto dell'UE Espandi tutto Riduci tutto G.A.S. GESELLSCHAFT FUR ANALYTISCHESENSORSYSTEME M.B.H. Germania Contribution nette de l'UE € 507 150,00 Indirizzo OTTO HAHN STRASSE 15 44227 Dortmund Mostra sulla mappa PMI L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione. Sì Regione Nordrhein-Westfalen Arnsberg Dortmund, Kreisfreie Stadt Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 724 500,00 STATISTICAMEDICA LIMITED Irlanda Contribution nette de l'UE € 462 087,50 Indirizzo 26 BELARMINE COURT ENNISKERRY ROAD STEPASIDE D18 DUBLIN Mostra sulla mappa PMI L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione. Sì Regione Ireland Eastern and Midland Dublin Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Collegamenti Contatta l’organizzazione Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 660 625,00 REDKNIGHT CONSULTANCY LTD Regno Unito Contribution nette de l'UE € 116 287,50 Indirizzo 21 THE DAIRY CF728TT PONTYCLUN Mostra sulla mappa PMI L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione. Sì Regione Wales West Wales and The Valleys Central Valleys Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Collegamenti Contatta l’organizzazione Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 166 125,00 THE UNIVERSITY OF WARWICK Regno Unito Contribution nette de l'UE € 140 422,50 Indirizzo Kirby Corner Road - University House CV4 8UW Coventry Mostra sulla mappa Regione West Midlands (England) West Midlands Coventry Tipo di attività Higher or Secondary Education Establishments Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 140 422,50
