Deciphering the transport mechanisms of small xenobiotic molecules in synthetic yeast cell factories

Risultati finali

The data management plan will address following issues: 1. Making data findable, 2. Making data openly Accessible, 3. Making data Interoperable, 4. Increase data Re-use, 5. Allocation of recourses and data security The data management plan will also specify if certain datasets remain closed and the reasons for not giving access will be given.

Pubblicazioni

Rational and evolutionary engineering of Saccharomyces cerevisiae for production of dicarboxylic acids from lignocellulosic biomass and exploring genetic mechanisms of the yeast tolerance to the biomass hydrolysate

Autori: Vratislav Stovicek; Laura Dato; Henrik Almqvist; Marie Schöpping; Ksenia Chekina; Lasse Ebdrup Pedersen; Anna Koza; Diogo Figueira; Freddy Tjosås; Bruno Sommer Ferreira; Jochen Forster; Gunnar Lidén; Irina Borodina
Pubblicato in: Crossref, Numero 1, 2022, ISSN 2731-3654
Editore: Biotechnology for Biofuels and Bioproducts
DOI: 10.1186/s13068-022-02121-1

Engineering Yeast Yarrowia lipolytica for Methanol Assimilation.

Autori: Guokun Wang; Guokun Wang; Mattis Olofsson-Dolk; Frederik Gleerup Hansson; Stefano Donati; Xiaolin Li; Hong Chang; Jian Cheng; Jonathan Dahlin; Irina Borodina
Pubblicato in: ACS Synthetic Biology, Numero 1, 2021, ISSN 2161-5063
Editore: American Chemical Society
DOI: 10.1021/acssynbio.1c00464

Metabolic Engineering of Saccharomyces cerevisiae for Rosmarinic Acid Production

Autori: Mahsa Babaei, Gheorghe M. Borja Zamfir, Xiao Chen, Hanne Bjerre Christensen, Mette Kristensen, Jens Nielsen, Irina Borodina
Pubblicato in: ACS Synthetic Biology, Numero 9/8, 2020, Pagina/e 1978-1988, ISSN 2161-5063
Editore: American Chemical Society
DOI: 10.1021/acssynbio.0c00048

Production of abscisic acid in the oleaginous yeast Yarrowia lipolytica

Autori: Jonathan Asmund Arnesen; Irene Hjorth Jacobsen; Jane Dannow Dyekjær; Daniela Rago; Mette Kristensen; Andreas Koedfoed Klitgaard; Milica Randelovic; José Luis Martinez; Irina Borodina
Pubblicato in: Crossref, Numero 1, 2022, ISSN 1567-1364
Editore: Oxford University press
DOI: 10.1093/femsyr/foac015

Modulation of the cell wall protein Ecm33p in yeast Saccharomyces cerevisiae improves the production of small metabolites

Autori: Verónica Ramos-Viana; Iben Møller-Hansen; Paul Kempen; Irina Borodina
Pubblicato in: FEMS Yeast Research, Numero 1, 2022, Pagina/e foac037, ISSN 1567-1356
Editore: Blackwell
DOI: 10.1093/femsyr/foac037

Efficient biodegradation of aliphatic polyester by genetically engineered strains of the yeast Yarrowia lipolytica

Autori: Katarzyna E. Kosiorowska; Xymena Połomska; Guokun Wang; Irina Borodina; Aleksandra M. Mirończuk
Pubblicato in: International Biodeterioration and Biodegradation, Numero 09648305, 2021, Pagina/e 105232, ISSN 0964-8305
Editore: Elsevier BV
DOI: 10.1016/j.ibiod.2021.105232

Resveratrol Production from Hydrothermally Pretreated Eucalyptus Wood Using Recombinant Industrial Saccharomyces cerevisiae Strains.

Autori: Carlos Costa; Iben Møller-Hansen; Aloia Romaní; José A. Teixeira; Irina Borodina; Lucília Domingues
Pubblicato in: reponame:Repositório Científico de Acesso Aberto de Portugal, Numero 1, 2021, ISSN 2161-5063
Editore: American Chemical Society
DOI: 10.1021/acssynbio.1c00120

Engineering of molybdenum-cofactor-dependent nitrate assimilation in Yarrowia lipolytica

Autori: Thomas Perli; Irina Borodina; Jean-Marc Daran
Pubblicato in: FEMS Yeast Research, Numero 1, 2021, ISSN 1567-1356
Editore: Blackwell
DOI: 10.1093/femsyr/foab050

An integrated yeast-based process for cis,cis-muconic acid production

Autori: Guokun Wang; Guokun Wang; Aline Tavares; Simone Schmitz; Simone Schmitz; Lucas Gabriel Souza França; Hugo Almeida; João Cavalheiro; Ana Carolas; Süleyman Øzmerih; Lars M. Blank; Bruno Sommer Ferreira; Irina Borodina
Pubblicato in: Biotechnology and Bioengineering, Numero 1, 2022, ISSN 0006-3592
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27992

Energetic evolution of cellular Transportomes

Autori: Behrooz Darbani, Douglas B. Kell, Irina Borodina
Pubblicato in: BMC Genomics, Numero 19/1, 2018, ISSN 1471-2164
Editore: BioMed Central
DOI: 10.1186/s12864-018-4816-5

Engineering energetically efficient transport of dicarboxylic acids in yeast Saccharomyces cerevisiae

Autori: Behrooz Darbani, Vratislav Stovicek, Steven Axel van der Hoek, Irina Borodina
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 116 (39), 2019, Pagina/e 201900287, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1900287116

The Transcriptome and Flux Profiling of Crabtree‐Negative Hydroxy Acid‐Producing Strains of Saccharomyces cerevisiae Reveals Changes in the Central Carbon Metabolism

Autori: Mathew M. Jessop‐Fabre, Jonathan Dahlin, Mathias B. Biron, Vratislav Stovicek, Birgitta E. Ebert, Lars M. Blank, Itay Budin, Jay D. Keasling, Irina Borodina
Pubblicato in: Biotechnology Journal, Numero 14/9, 2019, Pagina/e 1900013, ISSN 1860-6768
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.201900013

Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine

Autori: Steven A. van der Hoek, Behrooz Darbani, Karolina E. Zugaj, Bala Krishna Prabhala, Mathias Bernfried Biron, Milica Randelovic, Jacqueline B. Medina, Douglas B. Kell, Irina Borodina
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 7, 2019, ISSN 2296-4185
Editore: Frontiers
DOI: 10.3389/fbioe.2019.00262

Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica

Autori: Jonathan Dahlin, Carina Holkenbrink, Eko Roy Marella, Guokun Wang, Ulf Liebal, Christian Lieven, Dieter Weber, Douglas McCloskey, Birgitta E. Ebert, Markus J. Herrgård, Lars Mathias Blank, Irina Borodina
Pubblicato in: Frontiers in Genetics, Numero 10, 2019, ISSN 1664-8021
Editore: Frontiers Media
DOI: 10.3389/fgene.2019.00747

A single-host fermentation process for the production of flavor lactones from non-hydroxylated fatty acids

Autori: Eko Roy Marella, Jonathan Dahlin, Marie Inger Dam, Jolanda ter Horst, Hanne Bjerre Christensen, Suresh Sudarsan, Guokun Wang, Carina Holkenbrink, Irina Borodina
Pubblicato in: Metabolic Engineering, 2019, ISSN 1096-7176
Editore: Academic Press
DOI: 10.1016/j.ymben.2019.08.009

Improvement of cis , cis -Muconic Acid Production in Saccharomyces cerevisiae through Biosensor-Aided Genome Engineering

Autori: Guokun Wang, Süleyman Øzmerih, Rogério Guerreiro, Ana C. Meireles, Ana Carolas, Nicholas Milne, Michael K. Jensen, Bruno S. Ferreira, Irina Borodina
Pubblicato in: ACS Synthetic Biology, Numero 9/3, 2020, Pagina/e 634-646, ISSN 2161-5063
Editore: American Chemical Society
DOI: 10.1021/acssynbio.9b00477

A teaching protocol demonstrating the use of EasyClone and CRISPR/Cas9 for metabolic engineering of Saccharomyces cerevisiae and Yarrowia lipolytica

Autori: N Milne, L R R Tramontin, I Borodina
Pubblicato in: FEMS Yeast Research, Numero Volume 20, Numero 2, March 2020, foz062, 2020, ISSN 1567-1356
Editore: Blackwell
DOI: 10.1093/femsyr/foz062

Enhancement of Astaxanthin Biosynthesis in Oleaginous Yeast Yarrowia lipolytica via Microalgal Pathway

Autori: Larissa Ribeiro Ramos Tramontin, Kanchana Rueksomtawin Kildegaard, Suresh Sudarsan, Irina Borodina
Pubblicato in: Microorganisms, Numero 7/10, 2019, Pagina/e 472, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms7100472

Metabolic engineering of Saccharomyces cerevisiae for the de novo production of psilocybin and related tryptamine derivatives

Autori: N. Milne, P. Thomsen, N. Mølgaard Knudsen, P. Rubaszka, M. Kristensen, I. Borodina
Pubblicato in: Metabolic Engineering, Numero 60, 2020, Pagina/e 25-36, ISSN 1096-7176
Editore: Academic Press
DOI: 10.1016/j.ymben.2019.12.007

Engineering Oleaginous Yeast as the Host for Fermentative Succinic Acid Production From Glucose

Autori: Mahsa Babaei, Kanchana Rueksomtawin Kildegaard, Aligholi Niaei, Maryam Hosseini, Sirous Ebrahimi, Suresh Sudarsan, Irini Angelidaki, Irina Borodina
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 7, 2019, ISSN 2296-4185
Editore: Frontiers Media S.A.
DOI: 10.3389/fbioe.2019.00361

Identification and characterisation of two high-affinity glucose transporters from the spoilage yeast Brettanomyces bruxellensis

Autori: Ievgeniia A Tiukova, Iben Møller-Hansen, Zeinu M Belew, Behrooz Darbani, Eckhard Boles, Hussam H Nour-Eldin, Tomas Linder, Jens Nielsen, Irina Borodina
Pubblicato in: FEMS Microbiology Letters, Numero 366/17, 2019, ISSN 0378-1097
Editore: Blackwell
DOI: 10.1093/femsle/fnz222

Engineering ergothioneine production in Yarrowia lipolytica.

Autori: Steven Axel van der Hoek; Matej Rusnák; Irene Hjorth Jacobsen; José L. Martínez; Douglas B. Kell; Douglas B. Kell; Irina Borodina
Pubblicato in: van der Hoek , S A , Rusnák , M , Jacobsen , I H , Martínez , J L , Kell , D B & Borodina , I 2022 , ' Engineering ergothioneine production in Yarrowia lipolytica ' , FEBS Letters , vol. 596 , no. 10 , pp. 1356-1364 . https://doi.org/10.1002/1873-3468.14239, Numero 00145793, 2022, ISSN 0014-5793
Editore: Elsevier BV
DOI: 10.1002/1873-3468.14239

Transporter engineering in microbial cell factories: the ins, the outs, and the in-betweens.

Autori: Steven Axel van der Hoek; Irina Borodina
Pubblicato in: van der Hoek , S A & Borodina , I 2020 , ' Transporter engineering in microbial cell factories: the ins, the outs, and the in-betweens ' , Current Opinion in Biotechnology , vol. 66 , pp. 186-194 . https://doi.org/10.1016/j.copbio.2020.08.002, Numero 09581669, 2020, Pagina/e 186-194, ISSN 0958-1669
Editore: Elsevier BV
DOI: 10.1016/j.copbio.2020.08.002

Yarrowia lipolytica Strains Engineered for the Production of Terpenoids

Autori: Jonathan Asmund Arnesen, Kanchana Rueksomtawin Kildegaard, Marc Cernuda Pastor, Sidharth Jayachandran, Mette Kristensen, Irina Borodina
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 8, 2020, ISSN 2296-4185
Editore: Frontiers
DOI: 10.3389/fbioe.2020.00945

Transportome-wide engineering of Saccharomyces cerevisiae

Autori: Guokun Wang, Iben Møller-Hansen, Mahsa Babaei, Vasil D'Ambrosio, Hanne Bjerre Christensen, Behrooz Darbani, Michael Krogh Jensen, Irina Borodina
Pubblicato in: Metabolic Engineering, Numero 64, 2021, Pagina/e 52-63, ISSN 1096-7176
Editore: Academic Press
DOI: 10.1016/j.ymben.2021.01.007

Valorisation of wine wastes by de novo biosynthesis of resveratrol using a recombinant xylose-consuming industrial Saccharomyces cerevisiae strain

Autori: Carlos E. Costa; Aloia Romaní; Iben Møller-Hansen; José A. Teixeira; Irina Borodina; Lucília Domingues
Pubblicato in: Green Chem, Numero 24, 2022, Pagina/e 9128-9142, ISSN 1463-9262
Editore: Royal Society of Chemistry
DOI: 10.1039/d2gc02429b

Understanding metabolite transport gives an upper hand in strain development

Autori: Irina Borodina
Pubblicato in: Microbial Biotechnology, Numero 12/1, 2019, Pagina/e 69-70, ISSN 1751-7915
Editore: Wiley
DOI: 10.1111/1751-7915.13347

A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics

Autori: Sailesh Malla, Eric van der Helm, Behrooz Darbani, Stefan Wieschalka, Jochen Forster, Irina Borodina, Morten O. A. Sommer
Pubblicato in: 2020
Editore: biorxiv
DOI: 10.1101/2020.04.30.071142

Diritti di proprietà intellettuale

METHODS FOR PRODUCTION OF ERGOTHIONEINE

Numero candidatura/pubblicazione: 20 20061866
Data: 2020-04-29

METHODS FOR PRODUCTION OF ERGOTHIONEINE

Numero candidatura/pubblicazione: 20 20061866
Data: 2020-04-29

METHODS FOR PRODUCTION OF ERGOTHIONEINE

Numero candidatura/pubblicazione: 20 20061866
Data: 2020-04-29

Risultati finali

Pubblicazioni

Diritti di proprietà intellettuale

Condividi questa pagina

Scarica