Deciphering the transport mechanisms of small xenobiotic molecules in synthetic yeast cell factories

Rezultaty

The data management plan will address following issues: 1. Making data findable, 2. Making data openly Accessible, 3. Making data Interoperable, 4. Increase data Re-use, 5. Allocation of recourses and data security The data management plan will also specify if certain datasets remain closed and the reasons for not giving access will be given.

Publikacje

Rational and evolutionary engineering of Saccharomyces cerevisiae for production of dicarboxylic acids from lignocellulosic biomass and exploring genetic mechanisms of the yeast tolerance to the biomass hydrolysate

Autorzy: Vratislav Stovicek; Laura Dato; Henrik Almqvist; Marie Schöpping; Ksenia Chekina; Lasse Ebdrup Pedersen; Anna Koza; Diogo Figueira; Freddy Tjosås; Bruno Sommer Ferreira; Jochen Forster; Gunnar Lidén; Irina Borodina
Opublikowane w: Crossref, Numer 1, 2022, ISSN 2731-3654
Wydawca: Biotechnology for Biofuels and Bioproducts
DOI: 10.1186/s13068-022-02121-1

Engineering Yeast Yarrowia lipolytica for Methanol Assimilation.

Autorzy: Guokun Wang; Guokun Wang; Mattis Olofsson-Dolk; Frederik Gleerup Hansson; Stefano Donati; Xiaolin Li; Hong Chang; Jian Cheng; Jonathan Dahlin; Irina Borodina
Opublikowane w: ACS Synthetic Biology, Numer 1, 2021, ISSN 2161-5063
Wydawca: American Chemical Society
DOI: 10.1021/acssynbio.1c00464

Metabolic Engineering of Saccharomyces cerevisiae for Rosmarinic Acid Production

Autorzy: Mahsa Babaei, Gheorghe M. Borja Zamfir, Xiao Chen, Hanne Bjerre Christensen, Mette Kristensen, Jens Nielsen, Irina Borodina
Opublikowane w: ACS Synthetic Biology, Numer 9/8, 2020, Strona(/y) 1978-1988, ISSN 2161-5063
Wydawca: American Chemical Society
DOI: 10.1021/acssynbio.0c00048

Production of abscisic acid in the oleaginous yeast Yarrowia lipolytica

Autorzy: Jonathan Asmund Arnesen; Irene Hjorth Jacobsen; Jane Dannow Dyekjær; Daniela Rago; Mette Kristensen; Andreas Koedfoed Klitgaard; Milica Randelovic; José Luis Martinez; Irina Borodina
Opublikowane w: Crossref, Numer 1, 2022, ISSN 1567-1364
Wydawca: Oxford University press
DOI: 10.1093/femsyr/foac015

Modulation of the cell wall protein Ecm33p in yeast Saccharomyces cerevisiae improves the production of small metabolites

Autorzy: Verónica Ramos-Viana; Iben Møller-Hansen; Paul Kempen; Irina Borodina
Opublikowane w: FEMS Yeast Research, Numer 1, 2022, Strona(/y) foac037, ISSN 1567-1356
Wydawca: Blackwell
DOI: 10.1093/femsyr/foac037

Efficient biodegradation of aliphatic polyester by genetically engineered strains of the yeast Yarrowia lipolytica

Autorzy: Katarzyna E. Kosiorowska; Xymena Połomska; Guokun Wang; Irina Borodina; Aleksandra M. Mirończuk
Opublikowane w: International Biodeterioration and Biodegradation, Numer 09648305, 2021, Strona(/y) 105232, ISSN 0964-8305
Wydawca: Elsevier BV
DOI: 10.1016/j.ibiod.2021.105232

Resveratrol Production from Hydrothermally Pretreated Eucalyptus Wood Using Recombinant Industrial Saccharomyces cerevisiae Strains.

Autorzy: Carlos Costa; Iben Møller-Hansen; Aloia Romaní; José A. Teixeira; Irina Borodina; Lucília Domingues
Opublikowane w: reponame:Repositório Científico de Acesso Aberto de Portugal, Numer 1, 2021, ISSN 2161-5063
Wydawca: American Chemical Society
DOI: 10.1021/acssynbio.1c00120

Engineering of molybdenum-cofactor-dependent nitrate assimilation in Yarrowia lipolytica

Autorzy: Thomas Perli; Irina Borodina; Jean-Marc Daran
Opublikowane w: FEMS Yeast Research, Numer 1, 2021, ISSN 1567-1356
Wydawca: Blackwell
DOI: 10.1093/femsyr/foab050

An integrated yeast-based process for cis,cis-muconic acid production

Autorzy: Guokun Wang; Guokun Wang; Aline Tavares; Simone Schmitz; Simone Schmitz; Lucas Gabriel Souza França; Hugo Almeida; João Cavalheiro; Ana Carolas; Süleyman Øzmerih; Lars M. Blank; Bruno Sommer Ferreira; Irina Borodina
Opublikowane w: Biotechnology and Bioengineering, Numer 1, 2022, ISSN 0006-3592
Wydawca: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27992

Energetic evolution of cellular Transportomes

Autorzy: Behrooz Darbani, Douglas B. Kell, Irina Borodina
Opublikowane w: BMC Genomics, Numer 19/1, 2018, ISSN 1471-2164
Wydawca: BioMed Central
DOI: 10.1186/s12864-018-4816-5

Engineering energetically efficient transport of dicarboxylic acids in yeast Saccharomyces cerevisiae

Autorzy: Behrooz Darbani, Vratislav Stovicek, Steven Axel van der Hoek, Irina Borodina
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 116 (39), 2019, Strona(/y) 201900287, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1900287116

The Transcriptome and Flux Profiling of Crabtree‐Negative Hydroxy Acid‐Producing Strains of Saccharomyces cerevisiae Reveals Changes in the Central Carbon Metabolism

Autorzy: Mathew M. Jessop‐Fabre, Jonathan Dahlin, Mathias B. Biron, Vratislav Stovicek, Birgitta E. Ebert, Lars M. Blank, Itay Budin, Jay D. Keasling, Irina Borodina
Opublikowane w: Biotechnology Journal, Numer 14/9, 2019, Strona(/y) 1900013, ISSN 1860-6768
Wydawca: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.201900013

Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine

Autorzy: Steven A. van der Hoek, Behrooz Darbani, Karolina E. Zugaj, Bala Krishna Prabhala, Mathias Bernfried Biron, Milica Randelovic, Jacqueline B. Medina, Douglas B. Kell, Irina Borodina
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 7, 2019, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.3389/fbioe.2019.00262

Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica

Autorzy: Jonathan Dahlin, Carina Holkenbrink, Eko Roy Marella, Guokun Wang, Ulf Liebal, Christian Lieven, Dieter Weber, Douglas McCloskey, Birgitta E. Ebert, Markus J. Herrgård, Lars Mathias Blank, Irina Borodina
Opublikowane w: Frontiers in Genetics, Numer 10, 2019, ISSN 1664-8021
Wydawca: Frontiers Media
DOI: 10.3389/fgene.2019.00747

A single-host fermentation process for the production of flavor lactones from non-hydroxylated fatty acids

Autorzy: Eko Roy Marella, Jonathan Dahlin, Marie Inger Dam, Jolanda ter Horst, Hanne Bjerre Christensen, Suresh Sudarsan, Guokun Wang, Carina Holkenbrink, Irina Borodina
Opublikowane w: Metabolic Engineering, 2019, ISSN 1096-7176
Wydawca: Academic Press
DOI: 10.1016/j.ymben.2019.08.009

Improvement of cis , cis -Muconic Acid Production in Saccharomyces cerevisiae through Biosensor-Aided Genome Engineering

Autorzy: Guokun Wang, Süleyman Øzmerih, Rogério Guerreiro, Ana C. Meireles, Ana Carolas, Nicholas Milne, Michael K. Jensen, Bruno S. Ferreira, Irina Borodina
Opublikowane w: ACS Synthetic Biology, Numer 9/3, 2020, Strona(/y) 634-646, ISSN 2161-5063
Wydawca: American Chemical Society
DOI: 10.1021/acssynbio.9b00477

A teaching protocol demonstrating the use of EasyClone and CRISPR/Cas9 for metabolic engineering of Saccharomyces cerevisiae and Yarrowia lipolytica

Autorzy: N Milne, L R R Tramontin, I Borodina
Opublikowane w: FEMS Yeast Research, Numer Volume 20, Numer 2, March 2020, foz062, 2020, ISSN 1567-1356
Wydawca: Blackwell
DOI: 10.1093/femsyr/foz062

Enhancement of Astaxanthin Biosynthesis in Oleaginous Yeast Yarrowia lipolytica via Microalgal Pathway

Autorzy: Larissa Ribeiro Ramos Tramontin, Kanchana Rueksomtawin Kildegaard, Suresh Sudarsan, Irina Borodina
Opublikowane w: Microorganisms, Numer 7/10, 2019, Strona(/y) 472, ISSN 2076-2607
Wydawca: MDPI
DOI: 10.3390/microorganisms7100472

Metabolic engineering of Saccharomyces cerevisiae for the de novo production of psilocybin and related tryptamine derivatives

Autorzy: N. Milne, P. Thomsen, N. Mølgaard Knudsen, P. Rubaszka, M. Kristensen, I. Borodina
Opublikowane w: Metabolic Engineering, Numer 60, 2020, Strona(/y) 25-36, ISSN 1096-7176
Wydawca: Academic Press
DOI: 10.1016/j.ymben.2019.12.007

Engineering Oleaginous Yeast as the Host for Fermentative Succinic Acid Production From Glucose

Autorzy: Mahsa Babaei, Kanchana Rueksomtawin Kildegaard, Aligholi Niaei, Maryam Hosseini, Sirous Ebrahimi, Suresh Sudarsan, Irini Angelidaki, Irina Borodina
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 7, 2019, ISSN 2296-4185
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fbioe.2019.00361

Identification and characterisation of two high-affinity glucose transporters from the spoilage yeast Brettanomyces bruxellensis

Autorzy: Ievgeniia A Tiukova, Iben Møller-Hansen, Zeinu M Belew, Behrooz Darbani, Eckhard Boles, Hussam H Nour-Eldin, Tomas Linder, Jens Nielsen, Irina Borodina
Opublikowane w: FEMS Microbiology Letters, Numer 366/17, 2019, ISSN 0378-1097
Wydawca: Blackwell
DOI: 10.1093/femsle/fnz222

Engineering ergothioneine production in Yarrowia lipolytica.

Autorzy: Steven Axel van der Hoek; Matej Rusnák; Irene Hjorth Jacobsen; José L. Martínez; Douglas B. Kell; Douglas B. Kell; Irina Borodina
Opublikowane w: van der Hoek , S A , Rusnák , M , Jacobsen , I H , Martínez , J L , Kell , D B & Borodina , I 2022 , ' Engineering ergothioneine production in Yarrowia lipolytica ' , FEBS Letters , vol. 596 , no. 10 , pp. 1356-1364 . https://doi.org/10.1002/1873-3468.14239, Numer 00145793, 2022, ISSN 0014-5793
Wydawca: Elsevier BV
DOI: 10.1002/1873-3468.14239

Transporter engineering in microbial cell factories: the ins, the outs, and the in-betweens.

Autorzy: Steven Axel van der Hoek; Irina Borodina
Opublikowane w: van der Hoek , S A & Borodina , I 2020 , ' Transporter engineering in microbial cell factories: the ins, the outs, and the in-betweens ' , Current Opinion in Biotechnology , vol. 66 , pp. 186-194 . https://doi.org/10.1016/j.copbio.2020.08.002, Numer 09581669, 2020, Strona(/y) 186-194, ISSN 0958-1669
Wydawca: Elsevier BV
DOI: 10.1016/j.copbio.2020.08.002

Yarrowia lipolytica Strains Engineered for the Production of Terpenoids

Autorzy: Jonathan Asmund Arnesen, Kanchana Rueksomtawin Kildegaard, Marc Cernuda Pastor, Sidharth Jayachandran, Mette Kristensen, Irina Borodina
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 8, 2020, ISSN 2296-4185
Wydawca: Frontiers
DOI: 10.3389/fbioe.2020.00945

Transportome-wide engineering of Saccharomyces cerevisiae

Autorzy: Guokun Wang, Iben Møller-Hansen, Mahsa Babaei, Vasil D'Ambrosio, Hanne Bjerre Christensen, Behrooz Darbani, Michael Krogh Jensen, Irina Borodina
Opublikowane w: Metabolic Engineering, Numer 64, 2021, Strona(/y) 52-63, ISSN 1096-7176
Wydawca: Academic Press
DOI: 10.1016/j.ymben.2021.01.007

Valorisation of wine wastes by de novo biosynthesis of resveratrol using a recombinant xylose-consuming industrial Saccharomyces cerevisiae strain

Autorzy: Carlos E. Costa; Aloia Romaní; Iben Møller-Hansen; José A. Teixeira; Irina Borodina; Lucília Domingues
Opublikowane w: Green Chem, Numer 24, 2022, Strona(/y) 9128-9142, ISSN 1463-9262
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2gc02429b

Understanding metabolite transport gives an upper hand in strain development

Autorzy: Irina Borodina
Opublikowane w: Microbial Biotechnology, Numer 12/1, 2019, Strona(/y) 69-70, ISSN 1751-7915
Wydawca: Wiley
DOI: 10.1111/1751-7915.13347

A Novel Efficient L-Lysine Exporter Identified by Functional Metagenomics

Autorzy: Sailesh Malla, Eric van der Helm, Behrooz Darbani, Stefan Wieschalka, Jochen Forster, Irina Borodina, Morten O. A. Sommer
Opublikowane w: 2020
Wydawca: biorxiv
DOI: 10.1101/2020.04.30.071142

Prawa własności intelektualnej

METHODS FOR PRODUCTION OF ERGOTHIONEINE

Numer wniosku/publikacji: 20 20061866
Data: 2020-04-29

METHODS FOR PRODUCTION OF ERGOTHIONEINE

Numer wniosku/publikacji: 20 20061866
Data: 2020-04-29

METHODS FOR PRODUCTION OF ERGOTHIONEINE

Numer wniosku/publikacji: 20 20061866
Data: 2020-04-29

Rezultaty

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Prawa własności intelektualnej

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