Carbohydrate-based fine chemicals: Development of a glycosylation platform cell factory and optimization of downstream processing for the sustainable production of glycosides.

Informazioni relative al progetto

CARBAFIN

ID dell’accordo di sovvenzione: 761030

DOI

10.3030/761030

Progetto chiuso

Data della firma CE 20 Ottobre 2017

Data di avvio 1 Gennaio 2018

Data di completamento 30 Giugno 2022

Finanziato da

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology

Costo totale

€ 6 128 058,75

Contributo UE

€ 5 362 908,75

Coordinato da

ACIB GMBH
Austria

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Open Research Data Pilot (3)

First data management plan

Data management plan periodically updated

Third data management plan

Third data management plan periodically updated

Second data management plan

Second data management plan periodically updated

Other (1)

Installation of Stakeholder advisory board

Documents, reports (1)

"Report on output of online questionnaire of ""gender aspects in biotech jobs"""

Report on output of online questionnaire of gender aspects in biotech jobs

Pubblicazioni

Other (5)

Second data management plan

Autori: Christiane Luley
Pubblicato in: 2019
Editore: European Commission

Additional file 1 of Whole cell-based catalyst for enzymatic production of the osmolyte 2-O-α-glucosylglycerol

Autori: Schwaiger, Katharina N.; Cserjan-Puschmann, Monika; Striedner, Gerald; Nidetzky, Bernd
Pubblicato in: Microbial Cell Factories, 2021, ISSN 1475-2859
Editore: BioMed Central Ltd.
DOI: 10.6084/m9.figshare.14385634

First data management plan

Autori: Christiane Luley
Pubblicato in: 2018
Editore: European Commission

Additional file 1 of Kinetic modeling of phosphorylase-catalyzed iterative β-1,4-glycosylation for degree of polymerization-controlled synthesis of soluble cello-oligosaccharides

Autori: Klimacek, Mario; Zhong, Chao; Nidetzky, Bernd
Pubblicato in: Biotechnology for Biofuels and Bioproducts, 2021
Editore: Springer Nature
DOI: 10.6084/m9.figshare.14767225

Installation of Stakeholder advisory board

Autori: Christiane Luley
Pubblicato in: 2018
Editore: European Commission

Peer reviewed articles (23)

Plasmid Design for Tunable Two‐Enzyme Co‐Expression Promotes Whole‐Cell Production of Cellobiose

Autori: Schwaiger, Katharina N.; Voit, Alena; Dobiasová, Hana; Luley-Goedl, Christiane; Wiltschi, Birgit; Nidetzky, Bernd
Pubblicato in: Biotechnology Journal, 2020, ISSN 1860-7314
Editore: Wiley-VCH GmbH
DOI: 10.1002/biot.202000063

β-Glucan phosphorylases in carbohydrate synthesis

Autori: Zorica Ubiparip; Marc De Doncker; Koen Beerens; Jorick Franceus; Tom Desmet
Pubblicato in: Applied Microbiology and Biotechnology, Numero 4, 2021, ISSN 0175-7598
Editore: Springer Verlag
DOI: 10.1007/s00253-021-11320-z

Engineering of a Thermostable Biocatalyst for the Synthesis of 2-O-Glucosylglycerol.

Autori: Jorick Franceus; Zorica Ubiparip; Koen Beerens; Tom Desmet
Pubblicato in: ChemBioChem, Numero 2, 2021, ISSN 1439-7633
Editore: Wiley-VCH GmbH
DOI: 10.1002/cbic.202100192

Short-Chain Cello-oligosaccharides: Intensification and Scale-up of Their Enzymatic Production and Selective Growth Promotion among Probiotic Bacteria

Autori: Chao Zhong, Christina Ukowitz, Konrad J. Domig, Bernd Nidetzky
Pubblicato in: Journal of Agricultural and Food Chemistry, Numero 68/32, 2020, Pagina/e 8557-8567, ISSN 0021-8561
Editore: American Chemical Society
DOI: 10.1021/acs.jafc.0c02660

Whole cell-based catalyst for enzymatic production of the osmolyte 2- O -α-glucosylglycerol

Autori: Katharina N. Schwaiger; Monika Cserjan-Puschmann; Gerald Striedner; Bernd Nidetzky
Pubblicato in: Microbial Cell Factories, Numero 7, 2021, ISSN 1475-2859
Editore: BioMed Central
DOI: 10.1186/s12934-021-01569-4

On the donor substrate dependence of group‐transfer reactions by hydrolytic enzymes: Insight from kinetic analysis of sucrose phosphorylase‐catalyzed transglycosylation

Autori: Mario Klimacek, Alexander Sigg, Bernd Nidetzky
Pubblicato in: Biotechnology and Bioengineering, Numero 117/10, 2020, Pagina/e 2933-2943, ISSN 0006-3592
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27471

Reducing end thiol-modified nanocellulose: Bottom-up enzymatic synthesis and use for templated assembly of silver nanoparticles into biocidal composite material

Autori: Chao Zhong, Krisztina Zajki-Zechmeister, Bernd Nidetzky
Pubblicato in: Carbohydrate Polymers, 2021, ISSN 0144-8617
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2021.117772

Three-level hybrid modeling for systematic optimization of biocatalytic synthesis: α-glucosyl glycerol production by enzymatic trans-glycosylation from sucrose

Autori: Sigg, Alexander; Klimacek, Mario; Nidetzky, Bernd
Pubblicato in: Biotechnology and Bioengineering, Numero 2, 2021, ISSN 1097-0290
Editore: Wiley Periodicals, LLC
DOI: 10.1002/bit.27878

Engineering cascade biocatalysis in whole cells for bottom-up synthesis of cello-oligosaccharides: flux control over three enzymatic steps enables soluble production

Autori: Katharina N. Schwaiger, Alena Voit, Birgit Wiltschi, Bernd Nidetzky
Pubblicato in: Microbial Cell Factories, 2022, ISSN 1475-2859
Editore: BioMed Central
DOI: 10.1186/s12934-022-01781-w

Kinetic modeling of phosphorylase-catalyzed iterative β-1,4-glycosylation for degree of polymerization-controlled synthesis of soluble cello-oligosaccharides

Autori: Mario Klimacek; Chao Zhong; Bernd Nidetzky
Pubblicato in: Biotechnology for Biofuels, Numero 2, 2021, ISSN 2731-3654
Editore: BMC
DOI: 10.1186/s13068-021-01982-2

Engineering of cellobiose phosphorylase for the defined synthesis of cellotriose

Autori: Zorica Ubiparip, David Sáez Moreno, Koen Beerens, Tom Desmet
Pubblicato in: Applied Microbiology and Biotechnology, Numero 104/19, 2020, Pagina/e 8327-8337, ISSN 0175-7598
Editore: Springer Verlag
DOI: 10.1007/s00253-020-10820-8

Continuous process technology for glucoside production from sucrose using a whole cell-derived solid catalyst of sucrose phosphorylase.

Autori: Andreas Kruschitz; Linda Peinsipp; Martin Pfeiffer; Bernd Nidetzky
Pubblicato in: Applied Microbiology and Biotechnology, Numero 7, 2021, ISSN 0175-7598
Editore: Springer Verlag
DOI: 10.1007/s00253-021-11411-x

Product solubility control in cellooligosaccharide production by coupled cellobiose and cellodextrin phosphorylase

Autori: Chao Zhong, Christiane Luley‐Goedl, Bernd Nidetzky
Pubblicato in: Biotechnology and Bioengineering, Numero 116(9), 2019, Pagina/e 2146-2155, ISSN 0006-3592
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27008

Sucrose Phosphorylase and Related Enzymes in Glycoside Hydrolase Family 13: Discovery, Application and Engineering

Autori: Jorick Franceus, Tom Desmet
Pubblicato in: International Journal of Molecular Sciences, Numero 21/7, 2020, Pagina/e 2526, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072526

Three‐Enzyme Phosphorylase Cascade Immobilized on Solid Support for Biocatalytic Synthesis of Cello−oligosaccharides

Autori: Chao Zhong, Božidar Duić, Juan M. Bolivar, Bernd Nidetzky
Pubblicato in: ChemCatChem, Numero 12/5, 2020, Pagina/e 1350-1358, ISSN 1867-3880
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201901964

Downstream processing technologies in the biocatalytic production of oligosaccharides

Autori: Andreas Kruschitz, Bernd Nidetzky
Pubblicato in: Biotechnology Advances, Numero 43, 2020, Pagina/e 107568, ISSN 0734-9750
Editore: Elsevier BV
DOI: 10.1016/j.biotechadv.2020.107568

Removal of glycerol from enzymatically produced 2-α-d-glucosyl-glycerol by discontinuous diafiltration

Autori: Andreas Kruschitz, Bernd Nidetzky
Pubblicato in: Separation and Purification Technology, Numero 241, 2020, Pagina/e 116749, ISSN 1383-5866
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.seppur.2020.116749

Three‐Enzyme Phosphorylase Cascade for Integrated Production of Short‐Chain Cellodextrins

Autori: Chao Zhong, Bernd Nidetzky
Pubblicato in: Biotechnology Journal, Numero 15/3, 2020, Pagina/e 1900349, ISSN 1860-6768
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.201900349

Reactive extraction of fructose for efficient separation of sucrose-derived glucosides produced by enzymatic glycosylation

Autori: Kruschitz, Andreas; Nidetzky, Bernd
Pubblicato in: Green Chemistry, Numero 22(15), 2020, ISSN 1463-9270
Editore: Royal Society of Chemistry

Internal reporting on process optimization measures: combination of economic and environmental aspects

Autori: Rudolf Grünbichler, Barbara Petschacher, René Kollmann, Alexander Passer, Stefan Grbenic
Pubblicato in: FACTA UNIVERSITATIS, Series: Economics and Organization, 2021, ISSN 2406-050X
Editore: University of Nis
DOI: 10.22190/fueo210622030g

Precision synthesis of reducing-end thiol-modified cellulose enabled by enzyme selection

Autori: Chao Zhong; Bernd Nidetzky
Pubblicato in: Polymer Journal, Numero 7, 2021, ISSN 0032-3896
Editore: Nature Publishing Group
DOI: 10.1038/s41428-021-00599-4

Phosphorylase-catalyzed bottom-up synthesis of short-chain soluble cello-oligosaccharides and property-tunable cellulosic materials

Autori: Bernd Nidetzky, Chao Zhong
Pubblicato in: Biotechnology Advances, 2020, Pagina/e 107633, ISSN 0734-9750
Editore: Elsevier BV
DOI: 10.1016/j.biotechadv.2020.107633

Biocatalytic Production of 2-α-d-Glucosyl-glycerol for Functional Ingredient Use: Integrated Process Design and Techno-Economic Assessment

Autori: Andreas Kruschitz; Bernd Nidetzky
Pubblicato in: ACS Sustainable Chemistry & Engineering, 2022, ISSN 2168-0485
Editore: American Chemical Society
DOI: 10.1021/acssuschemeng.1c07210

Diritti di proprietà intellettuale

Patent (1)

COSMETIC COMPOSITION COMPRISING CELLODEXTRINS

Numero candidatura/pubblicazione: 20 21062167
Data: 2021-05-07
Candidato/i: PFEIFER & LANGEN GMBH & CO KG