Description du projet
Formation scientifique complexe pour lutter contre des pathologies complexes comme le syndrome cardio-rénal
Le syndrome cardio-rénal (SCR) est une affection du cœur, des vaisseaux sanguins et des reins, y compris les cas de maladies cardiovasculaires (MCV) chez les patients atteints de maladie rénale chronique (MRC). Financé par le programme Actions Marie Skłodowska-Curie, le projet CaReSyAn vise à améliorer la compréhension, le diagnostic et la thérapie du SCR en formant des spécialistes pour les rendre capables d’utiliser les technologies omiques, la bio-informatique et les analyses intégratives dans leurs recherches. CaReSyAn complétera d’autres programmes européens consacrés à la recherche sur la maladie rénale chronique ou les maladies cardiovasculaires et tirera parti des cohortes de patients disponibles, des technologies de pointe et de la coopération établie. Le fait de favoriser le développement de scientifiques ayant reçu une formation générale et capables de combler le fossé entre la recherche clinique et la recherche fondamentale devrait contribuer de manière significative à la lutte contre des maladies complexes telles que le SCR.
Objectif
Successfully combatting a complex disease requires multi-disciplinary and methodically well-trained scientists. CaReSyAn strives to accomplish exactly this: we will train scientists to successfully integrate proteomics, clinical, experimental and bioinformatical analyses to enhance the understanding, diagnosis and therapy of the cardiorenal syndrome (CRS). CRS comprises disorders of the heart, vessels and kidneys, including the increased development of cardiovascular disease (CVD) in patients with chronic kidney disease (CKD). With ~45% of all deaths in CKD patients caused by CVD, the socio-economic burden of CRS is extremely high.
CaReSyAn will train scientists in a close cooperation between academia, SME and industry partners. Key objectives are to provide: 1) Excellent scientific training on CRS pathology, integrating clinical/mechanistic knowledge with technological skills (animals and in vitro, molecular and functional studies, proteomics and bioinformatics) to generate innovative insights triggering the understanding, diagnosis and treatment of the CRS; 2) Excellent complementary skills in personal and career development as well as business training required to extend beyond scientific research; and 3) Exposure to both academic and non-academic environments, required to build bridges between researchers and entrepreneurs and support the future translation of research findings in innovative products and services.
CaReSyAn builds on already available patient cohorts, advanced technologies and established cooperations. CaReSyAn is complementary to ongoing European programs focusing solely on CKD or CVD and strives to synergistically improve structural training on European level. CaReSyAn will nurture the development of young, broadly-trained scientists able to successfully bridge clinical with basic research as well as academia and industry. This is a cornerstone in effectively combatting complex diseases as CRS, a major killer of this century.
Champ scientifique
- natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomics
- social scienceseconomics and businessbusiness and managemententrepreneurship
- medical and health sciencesclinical medicinecardiologycardiovascular diseases
- medical and health sciencesbasic medicinepathology
- medical and health sciencesclinical medicinenephrologykidney diseases
Programme(s)
Régime de financement
MSCA-ITN-ETN - European Training NetworksCoordinateur
52074 Aachen
Allemagne