Highly Integrated Nanoscale Robots for Targeted Delivery to the Central Nervous System

Informazioni relative al progetto

HINBOTS

ID dell’accordo di sovvenzione: 771565

DOI

10.3030/771565

Progetto chiuso

Data della firma CE 31 Gennaio 2018

Data di avvio 1 Settembre 2018

Data di completamento 31 Agosto 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 998 720,00

Contributo UE

€ 1 998 720,00

Coordinato da

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (40)

Biodegradation of Oxide Nanoparticles in Apoferritin Protein Media: A Systematic Electrochemical Approach

Autori: Ehsan Rahimi, Donghoon Kim, Ruben Offoiach, Roger Sanchis-Gual, Xiang-Zhong Chen, Peyman Taheri, Yaiza Gonzalez-Garcia, Johannes M. C. Mol, Lorenzo Fedrizzi, Salvador Pané, Maria Lekka
Pubblicato in: Advanced Materials Interfaces, 2023, Pagina/e 2300558, ISSN 2196-7350
Editore: Wiley-VCH GmbH
DOI: 10.1002/admi.202300558

Shape-memory effect in twisted ferroic nanocomposites

Autori: Donghoon Kim; Minsoo Kim; Steffen Reidt; Hyeon Han; Ali Baghizadeh; Peng Zeng; Hongsoo Choi; Josep Puigmartí-Luis; Morgan Trassin; Bradley J. Nelson; Xiang-Zhong Chen; Salvador Pané
Pubblicato in: Nature Communications, 14, Numero 8, 2023, Pagina/e 750, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.3929/ethz-b-000598013

Mechanically interlocked 3D multi-material micromachines

Autori: C. C. J. Alcântara, F. C. Landers, S. Kim, C. De Marco, D. Ahmed, B. J. Nelson, S. Pané
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-19725-6

Magnetically Driven Micro and Nanorobots

Autori: Huaijuan Zhou; Carmen C. Mayorga-Martinez; Salvador Pané; Li Zhang; Martin Pumera
Pubblicato in: Chemical Reviews 121(8), 2021, Pagina/e 4999-5041, ISSN 1520-6890
Editore: American Chemcial Society
DOI: 10.1021/acs.chemrev.0c01234

CANDYBOTS: A New Generation of 3D‐Printed Sugar‐Based Transient Small‐Scale Robots

Autori: Simone Gervasoni, Anastasia Terzopoulou, Carlos Franco, Andrea Veciana, Norman Pedrini, Jan T. Burri, Carmela de Marco, Erdem C. Siringil, Xiang‐Zhong Chen, Bradley J. Nelson, Josep Puigmartí‐Luis, Salvador Pané
Pubblicato in: Advanced Materials, Numero 32/52, 2020, Pagina/e 2005652, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202005652

Magnetoelectric coupling in micropatterned BaTiO3/CoFe2O4 epitaxial thin film structures: Augmentation and site-dependency

Autori: Donghoon Kim; Marta D. Rossell; Marco Campanini; Rolf Erni; Josep Puigmartí-Luis; Xiang-Zhong Chen; Salvador Pané
Pubblicato in: Applied Physics Letters, 119, Numero 3, 2021, Pagina/e 012901, ISSN 1077-3118
Editore: American Physics Letter
DOI: 10.1063/5.0056038

Catalytically Propelled Micro‐ and Nanoswimmers

Autori: Bumjin Jang, Min Ye, Ayoung Hong, Xiaopu Wang, Xianghong Liu, Dohyeok Bae, Josep Puigmartí Luis, Salvador Pané
Pubblicato in: Small Science, 2023, Pagina/e 2300076, ISSN 2688-4046
Editore: Wiley-VCH GmbH
DOI: 10.1002/smsc.202300076

Magnetoelectric Effect in Hydrogen Harvesting: Magnetic Field as a Trigger of Catalytic Reactions

Autori: Donghoon Kim; Ipek Efe; Harun Torlakcik; Anastasia Terzopoulou; Andrea Veciana; Erdem Siringil; Fajer Mushtaq; Carlos Franco; Denis Arx; Semih Sevim; Josep Puigmartí‐Luis; Bradley Nelson; Nicola A. Spaldin; Chiara Gattinoni; Xiang‐Zhong Chen; Salvador Pané
Pubblicato in: Advanced Materials, 34 (19), Numero 10, 2022, Pagina/e 2110612, ISSN 1521-4095
Editore: Wiley-VCH
DOI: 10.1002/adma.202110612

The magnetopyroelectric effect: heat-mediated magnetoelectricity in magnetic nanoparticle-ferroelectric polymer composites

Autori: Joaquin Llacer-Wintle; Jan Renz; Lukas Hertle; Andrea Veciana; Denis von Arx; Jiang Wu; Pere Bruna; Marija Vukomanovic; Josep Puigmartí-Luis; Bradley J. Nelson; Xiang-Zhong Chen; Salvador Pané
Pubblicato in: Materials Horizons, Numero 10 (7), 2023, Pagina/e 2627-2637, ISSN 2051-6347
Editore: The Royal Society of Chemistry
DOI: 10.1039/d2mh01361d

Advanced technologies for the fabrication of MOF thin films

Autori: Chiara Crivello, Semih Sevim, Octavio Graniel, Carlos Franco, Salvador Pané, Josep Puigmartí-Luis, David Muñoz-Rojas
Pubblicato in: Materials Horizons, Numero 8/1, 2021, Pagina/e 168-178, ISSN 2051-6347
Editore: Royal Chemical Society
DOI: 10.1039/d0mh00898b

MoSBOTs: Magnetically Driven Biotemplated MoS2-Based Microrobots for Biomedical Applications

Autori: de la Asuncion-Nadal, Victor; Veciana, Andrea; Ning, Shen; Terzopoulou, Anastasia; Sevim, Semih; Chen, Xiang-Zhong; Gong, De; Cai, Jun; Wendel-Garcia, Pedro; Jurado-Sanchez, Beatriz; Escarpa, Alberto; Puigmartí-Luis, Josep; Pané, Salvador
Pubblicato in: Small, 18 (33), Numero 5, 2022, Pagina/e 2203821, ISSN 1613-6829
Editore: Wiley-VCH
DOI: 10.3929/ethz-b-000560734

Inkjet-Assisted Electroformation of Magnetically Guidable Water Striders for Interfacial Microfluidic Manipulation

Autori: Bernasconi, Roberto; Carniani, Davide; Kim, Min-Soo; Pané, Salvador; Magagnin, Luca
Pubblicato in: ACS Applied Materials & Interface 15(1), 2023, Pagina/e 2396-2408, ISSN 1944-8252
Editore: American Chemical Society
DOI: 10.1021/acsami.2c17792

A Biodegradable Magnetic Microrobot Based on Gelatin Methacrylate for Precise Delivery of Stem Cells with Mass Production Capability

Autori: Seungmin Noh; Sungwoong Jeon; Eunhee Kim; Untaek Oh; Danbi Park; Sun Hwa Park; Sung Won Kim; Salvador Pané; Bradley J. Nelson; Jin‐young Kim; Hongsoo Choi
Pubblicato in: Small, 18 (25), Numero 4, 2022, Pagina/e 2107888, ISSN 1613-6829
Editore: Wiley-VCH
DOI: 10.1002/smll.202107888

Metal–Organic Frameworks in Motion

Autori: Anastasia Terzopoulou, James D. Nicholas, Xiang-Zhong Chen, Bradley J. Nelson, Salvador Pané, Josep Puigmartí-Luis
Pubblicato in: Chemical Reviews, Numero 120/20, 2020, Pagina/e 11175-11193, ISSN 0009-2665
Editore: American Chemical Society
DOI: 10.1021/acs.chemrev.0c00535

Thermoset Shape Memory Polymer Variable Stiffness 4D Robotic Catheters.

Autori: Michael Mattmann; Carmela De Marco; Francesco Briatico; Stefano Tagliabue; Aron Colusso; Xiang-Zhong Chen; Jonas Lussi; Christophe Chautems; Salvador Pané; Bradley J. Nelson
Pubblicato in: Advanced Science, Vol 9, Iss 1, Pp n/a-n/a (2022), Numero 4, 2022, Pagina/e 2103277, ISSN 2198-3844
Editore: Wiley-VCH
DOI: 10.1002/advs.202103277

Piezoelectric Nanomaterials Activated by Ultrasound: The Pathway from Discovery to Future Clinical Adoption.

Autori: A. Cafarelli; Attilio Marino; Lorenzo Vannozzi; Josep Puigmartí-Luis; Salvador Pané; Gianni Ciofani; Leonardo Ricotti
Pubblicato in: ACS Nano 15(7), 2021, Pagina/e 11066-11086, ISSN 1936-086X
Editore: American Chemical Society
DOI: 10.1021/acsnano.1c03087

Challenges and Strategies for Optimizing Corrosion and Biodegradation Stability of Biomedical Micro‐ and Nanoswimmers: A Review

Autori: Ehsan Rahimi; Roger Sanchis‐Gual; Xiangzhong Chen; Amin Imani; Yaiza Gonzalez‐Garcia; Edouard Asselin; Arjan Mol; Lorenzo Fedrizzi; Salvador Pané; Maria Lekka
Pubblicato in: Advanced Functional Materials, Numero 33/44, 2023, Pagina/e 2210345, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202210345

Biotemplating of Metal-Organic Framework Nanocrystals for Applications in Small-Scale Robotics

Autori: Anastasia Terzopoulou; Mario Palacios‐Corella; Carlos Franco; Semih Sevim; Thomas Dysli; Fajer Mushtaq; María Romero‐Angel; Carlos Martí‐Gastaldo; De Gong; Jun Cai; Xiang‐Zhong Chen; Martin Pumera; Andrew J. deMello; Bradley J. Nelson; Salvador Pané; Josep Puigmartí‐Luis
Pubblicato in: Advanced Functional Materials 32 (13), 2022, Pagina/e 2107421, ISSN 1616-3028
Editore: Wiley-VCH
DOI: 10.1002/adfm.202107421

Multi-target cell therapy using a magnetoelectric microscale biorobot for targeted delivery and selective differentiation of SH-SY5Y cells <i>via</i> magnetically driven cell stamping

Autori: Hyunseok Song; Dong-in Kim; Sarmad Ahmad Abbasi; Nader Latifi Gharamaleki; Eunhee Kim; Chaewon Jin; Samhwan Kim; Junsun Hwang; Jin-Young Kim; Xiang-Zhong Chen; Bradley J. Nelson; Salvador Pané; Hongsoo Choi
Pubblicato in: Material Horizon, Numero 9, 2022, Pagina/e 3031-3038, ISSN 2051-6347
Editore: Royal Society of Chemistry
DOI: 10.1039/d2mh00693f

Strain-Sensitive Flexible Magnetoelectric Ceramic Nanocomposites

Autori: Kim, Min-Soo; Kim, Donghoon; Aktas, Buse; Choi, Hongsoo, Puigmartí-Luis, Josep; Nelson Bradley; Pané, Salvador; Chen, Xiang-Zhong
Pubblicato in: Advanced Materials Technologies 8 (6), 2023, Pagina/e 2202097, ISSN 2365-709X
Editore: Wiley
DOI: 10.1002/admt.202202097

3D Printed Template-Assisted Casting of Biocompatible Polyvinyl Alcohol-Based Soft Microswimmers with Tunable Stability

Autori: Roger Sanchis-Gual, Hao Ye, Towa Ueno, Fabian C. Landers, Lukas Hertle, Siyu Deng, Andrea Veciana, Yanming Xia, Carlos Franco, Hongsoo Choi, Josep Puigmartí-Luis, Bradley J. Nelson, Salvador Pané
Pubblicato in: Advanced Functional Materials 2023, 2023, Pagina/e 2212952, ISSN 1616-3028
Editore: Wiley-VCH
DOI: 10.1002/adfm.202212952

Helical Klinotactic Locomotion of Two‐Link Nanoswimmers with Dual‐Function Drug‐Loaded Soft Polysaccharide Hinges

Autori: Jiaen Wu, Bumjin Jang, Yuval Harduf, Zvi Chapnik, Ömer Bartu Avci, Xiangzhong Chen, Josep Puigmartí‐Luis, Olgac Ergeneman, Bradley J. Nelson, Yizhar Or, Salvador Pané
Pubblicato in: Advanced Science, Numero 8/8, 2021, Pagina/e 2004458, ISSN 2198-3844
Editore: Wiley
DOI: 10.1002/advs.202004458

Shape Memory Alloy (SMA) Actuators: The Role of Material, Form, and Scaling Effects

Autori: Min‐Soo Kim; Jae‐Kyung Heo; Hugo Rodrigue; Hyun‐Taek Lee; Salvador Pané; Min‐Woo Han; Sung‐Hoon Ahn
Pubblicato in: Advanced Materials, Numero 35 (33), 2023, Pagina/e 2208517, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202208517

High‐Resolution SPECT Imaging of Stimuli‐Responsive Soft Microrobots

Autori: Veronica Iacovacci, Alain Blanc, Henwei Huang, Leonardo Ricotti, Roger Schibli, Arianna Menciassi, Martin Behe, Salvador Pané, Bradley J. Nelson
Pubblicato in: Small, Numero 15/34, 2019, Pagina/e 1900709, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201900709

Strain gradient mediated magnetoelectricity in Fe-Ga/P(VDF-TrFE) multiferroic bilayers integrated on silicon

Autori: Aliona Nicolenco, Andrés Gómez, Xiang-Zhong Chen, Enric Menéndez, Jordina Fornell, Salvador Pané, Eva Pellicer, Jordi Sort
Pubblicato in: Applied Materials Today, Numero 19, 2020, Pagina/e 100579, ISSN 2352-9407
Editore: Elsevier
DOI: 10.1016/j.apmt.2020.100579

MOFBOTS: Metal–Organic‐Framework‐Based Biomedical Microrobots

Autori: Xiaopu Wang, Xiang‐Zhong Chen, Carlos C. J. Alcântara, Semih Sevim, Marcus Hoop, Anastasia Terzopoulou, Carmela de Marco, Chengzhi Hu, Andrew J. de Mello, Paolo Falcaro, Shuhei Furukawa, Bradley J. Nelson, Josep Puigmartí‐Luis, Salvador Pané
Pubblicato in: Advanced Materials, Numero 31/27, 2019, Pagina/e 1901592, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201901592

Tissue response to neural implants: the use of model systems towards new design solutions of implantable microelectrodes

Autori: Gulino, Maurizio; Kim, Donghoon; Pané, Salvador; Santos, Sofia Duque; Pêgo, Ana Paula
Pubblicato in: Frontiers in Neuroscience, Vol 13 (2019), Numero 13, 2019, Pagina/e 689, ISSN 1662-453X
Editore: Frontiers Media
DOI: 10.3929/ethz-b-000354228

In‐Flow MOF Lithography

Autori: Semih Sevim, Carlos Franco, Hongjun Liu, Hervé Roussel, Laetitia Rapenne, Juan Rubio‐Zuazo, Xiang‐Zhong Chen, Salvador Pané, David Muñoz‐Rojas, Andrew J. deMello, Josep Puigmartí‐Luis
Pubblicato in: Advanced Materials Technologies, Numero 4/6, 2019, Pagina/e 1800666, ISSN 2365-709X
Editore: Wiley
DOI: 10.1002/admt.201800666

Imaging Technologies for Biomedical Micro‐ and Nanoswimmers

Autori: Salvador Pané, Josep Puigmartí‐Luis, Christos Bergeles, Xiang‐Zhong Chen, Eva Pellicer, Jordi Sort, Vanda Počepcová, Antoine Ferreira, Bradley J. Nelson
Pubblicato in: Advanced Materials Technologies, Numero 4/4, 2019, Pagina/e 1800575, ISSN 2365-709X
Editore: Wiley
DOI: 10.1002/admt.201800575

3D‐Printed Soft Magnetoelectric Microswimmers for Delivery and Differentiation of Neuron‐Like Cells

Autori: Mei Dong, Xiaopu Wang, Xiang‐Zhong Chen, Fajer Mushtaq, Siyu Deng, Caihong Zhu, Harun Torlakcik, Anastasia Terzopoulou, Xiao‐Hua Qin, Xuanzhong Xiao, Josep Puigmartí‐Luis, Hongsoo Choi, Ana Paula Pêgo, Qun‐Dong Shen, Bradley J. Nelson, Salvador Pané
Pubblicato in: Advanced Functional Materials, Numero 30/17, 2020, Pagina/e 1910323, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201910323

Biomimetic Synthesis of Sub-20 nm Covalent Organic Frameworks in Water

Autori: Carlos Franco, David Rodríguez-San-Miguel, Alessandro Sorrenti, Semih Sevim, Ramon Pons, Ana E. Platero-Prats, Marko Pavlovic, Istvan Szilágyi, M. Luisa Ruiz Gonzalez, José M. González-Calbet, Davide Bochicchio, Luca Pesce, Giovanni M. Pavan, Inhar Imaz, Mary Cano-Sarabia, Daniel Maspoch, Salvador Pané, Andrew J. de Mello, Felix Zamora, Josep Puigmartí-Luis
Pubblicato in: Journal of the American Chemical Society, Numero 142/7, 2020, Pagina/e 3540-3547, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.9b12389

Magnetic PiezoBOTs: a microrobotic approach for targeted amyloid protein dissociation

Autori: Shen Ning, Roger Sanchis-Gual, Carlos Franco, Pedro D. Wendel-Garcia, Hao Ye, Andrea Veciana, Qiao Tang, Semih Sevim, Lukas Hertle, Joaquin Llacer-Wintle, Xiao-Hua Qin, Caihong Zhu, Jun Cai, Xiangzhong Chen, Bradley J. Nelson, Josep Puigmartí-Luis and Salvador Pané
Pubblicato in: Nanoscale, Numero 15, 2023, Pagina/e 14800, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/d3nr02418k

Conductive properties of triphenylene MOFs and COFs

Autori: Contreras-Pereda, Noemi; Pané, Salvador; Puigmartí-Luis, Josep; Ruiz-Molina, Daniel
Pubblicato in: Coordination Chemistry Reviews, Numero 460, 2022, Pagina/e 214459, ISSN 0010-8545
Editore: Elsevier BV
DOI: 10.1016/j.ccr.2022.214459

Enhanced Piezocatalytic Performance of BaTiO$_3$ Nanosheets with Highly Exposed {001} Facets

Autori: Tang, Qiao; Wu, Jiang; Kim, Donghoon; Franco, Carlos; Terzopoulou, Anastasia; Veciana, Andrea; Puigmartí-Luis, Josep; Chen, Xiang-Zhong; Nelson, Bradley J.; Pané, Salvador
Pubblicato in: Advanced Functional Materials, 32 (35), Numero 2, 2022, Pagina/e 2202180, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.3929/ethz-b-000555906

Biodegradable Metal–Organic Framework‐Based Microrobots (MOFBOTs)

Autori: Anastasia Terzopoulou, Xiaopu Wang, Xiang‐Zhong Chen, Mario Palacios‐Corella, Carlos Pujante, Javier Herrero‐Martín, Xiao‐Hua Qin, Jordi Sort, Andrew J. deMello, Bradley J. Nelson, Josep Puigmartí‐Luis, Salvador Pané
Pubblicato in: Advanced Healthcare Materials, Numero 9/20, 2020, Pagina/e 2001031, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202001031

3D Motion Manipulation for Micro‐ and Nanomachines: Progress and Future Directions

Autori: Hai Huang, Shihao Yang, Yulong Ying, Xiangzhong Chen, Josep Puigmartí-Luis, Li Zhang and Salvador Pané
Pubblicato in: Advanced Materials, 2023, Pagina/e 2305925, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202305925

Biodegradable Small-Scale Swimmers for Biomedical Applications.

Autori: Joaquin Llacer-Wintle; Antón Rivas-Dapena; Xiang-Zhong Chen; Eva Pellicer; Bradley J. Nelson; Josep Puigmartí-Luis; Salvador Pané
Pubblicato in: Advanced Materials 33(42), 2021, Pagina/e 2102049, ISSN 1521-4095
Editore: Wiley-CH
DOI: 10.1002/adma.202102049

Magnetically Guided Catheters, Micro- and Nanorobots for Spinal Cord Stimulation

Autori: Torlakcik, Harun; Sarica, Can; Bayer, Patrick; Yamamoto, Kazuaki; Iori-Morin, Christian; Hodaie, Mojgan; Kalia, Suneil K.; Neimat, Joseph S.; Hernesniemi, Juha; Bhatia, Anuj; Nelson, Bradley J.; Pané, Salvador; Lozano, Andres M.; Zemmar, Ajmal
Pubblicato in: Forntiers in Neurorobotics, Numero 15, 2021, ISSN 1662-5218
Editore: Frontiers Research Foundation
DOI: 10.3389/fnbot.2021.749024

Tuning oxygen vacancies in Bi4Ti3O12 nanosheets to boost piezo-photocatalytic activity

Autori: Qiao Tang; Jiang Wu; Xiang-Zhong Chen; Roger Sanchis-Gual; Andrea Veciana; Carlos Franco; Donghoon Kim; Ivan Surin; Javier Pérez-Ramírez; Michele Mattera; Anastasia Terzopoulou; Ni Qin; Marija Vukomanovic; Bradley J. Nelson; Josep Puigmartí-Luis; Salvador Pané
Pubblicato in: Nano Energy, 108, Numero 2, 2023, Pagina/e 108202, ISSN 2211-2855
Editore: Elsevier BV
DOI: 10.1016/j.nanoen.2023.108202

In flow-based technologies: A new paradigm for the synthesis and processing of covalent-organic frameworks

Autori: Martinez-Bulit, Pablo; Sorrenti, Alessandro; Rodriguez San Miguel, David; Mattera, Michele; Belce, Yonca; Xia, Yanming; Ma, Shenglin, Huang, Mu-Hua, Pané, Salvador; Pugimartí-Luis, Josep
Pubblicato in: Chemical Engineering Journal 435(3), 2022, Pagina/e 135117, ISSN 1385-8947
Editore: Elsevier BV
DOI: 10.1016/j.cej.2022.135117

Book chapters (1)

Powering and Fabrication of Small-Scale Robotics Systems

Autori: Salvador Pané; Pedro D. Wendel-García; Yonca Belce; Xiang-Zhong Chen; Josep Puigmartí-Luis
Pubblicato in: Current Robotics Reports, 2 (4), Numero 10, 2021, Pagina/e 427-440
Editore: Springer
DOI: 10.1007/s43154-021-00066-1

Conference proceedings (1)

Shape memory polymer variable stiffness magnetic catheters with hybrid stiffness control

Autori: Mattmann, Michael; Boehler, Quentin; Chen, Xiang-Zhong; Pané, Salvador; Nelson, Bradley
Pubblicato in: 2022 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), Numero 8, 2022, Pagina/e 9589-9595, ISBN 978-1-6654-7927-1
Editore: IEEE
DOI: 10.1109/iros47612.2022.9981935