Chromatin-localized central metabolism regulating gene expression and cell identity

Pubblicazioni

Metabolic modulation of transcription: The role of one-carbon metabolism

Autori: Jung-Ming G Lin, Savvas Kourtis, Ritobrata Ghose, Natalia Pardo Lorente, Stefan Kubicek, Sara Sdelci
Pubblicato in: Cell Chem Biol., Numero S2451, 2022, Pagina/e 9456(22)00415-9, ISSN 2451-9448
Editore: Cell Press
DOI: 10.1016/j.chembiol.2022.11.009

Acute BAF perturbation causes immediate changes in chromatin accessibility

Autori: Sandra Schick, Sarah Grosche, Katharina Eva Kohl, Danica Drpic, Martin G. Jaeger, Nara C. Marella, Hana Imrichova, Jung-Ming G. Lin, Gerald Hofstätter, Michael Schuster, André F. Rendeiro, Anna Koren, Mark Petronczki, Christoph Bock, André C. Müller, Georg E. Winter, Stefan Kubicek
Pubblicato in: Nature Genetics, Numero 53/3, 2021, Pagina/e 269-278, ISSN 1061-4036
Editore: Nature Publishing Group
DOI: 10.1038/s41588-021-00777-3

Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets

Autori: Brenda Marquina-Sanchez, Nikolaus Fortelny, Matthias Farlik, Andhira Vieira, Patrick Collombat, Christoph Bock, Stefan Kubicek
Pubblicato in: Genome Biology, Numero 21(1), 2020, Pagina/e 106, ISSN 1474-760X
Editore: Biomed Central
DOI: 10.1186/s13059-020-02006-2

Cell-surface SLC nucleoside transporters and purine levels modulate BRD4-dependent chromatin states

Autori: Kai-Chun Li, Enrico Girardi, Felix Kartnig, Sarah Grosche, Tea Pemovska, Johannes W. Bigenzahn, Ulrich Goldmann, Vitaly Sedlyarov, Ariel Bensimon, Sandra Schick, Jung-Ming G. Lin, Bettina Gürtl, Daniela Reil, Kristaps Klavins, Stefan Kubicek, Sara Sdelci, Giulio Superti-Furga
Pubblicato in: Nature Metabolism, Numero 3/5, 2021, Pagina/e 651-664, ISSN 2522-5812
Editore: Nature Metabolism
DOI: 10.1038/s42255-021-00386-8

Therapeutic targeting of chromatin: Status and opportunities

Autori: Marton Siklos, Stefan Kubicek
Pubblicato in: The FEBS Journal, 2021, ISSN 1742-464X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/febs.15966

SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression

Autori: Tamara Casteels; Simon Bajew; Jiří Reiniš; Lennart Enders; Michael Schuster; Frédéric Fontaine; André C. Müller; Bridget K. Wagner; Christoph Bock; Stefan Kubicek
Pubblicato in: Cell Reports, Numero 1, 2022, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2022.111288

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation

Autori: Sara Sdelci, André F. Rendeiro, Philipp Rathert, Wanhui You, Jung-Ming G. Lin, Anna Ringler, Gerald Hofstätter, Herwig P. Moll, Bettina Gürtl, Matthias Farlik, Sandra Schick, Freya Klepsch, Matthew Oldach, Pisanu Buphamalai, Fiorella Schischlik, Peter Májek, Katja Parapatics, Christian Schmidl, Michael Schuster, Thomas Penz, Dennis L. Buckley, Otto Hudecz, Richard Imre, Shuang-Yan Wang, Hans M
Pubblicato in: Nature Genetics, Numero 51/6, 2019, Pagina/e 990-998, ISSN 1061-4036
Editore: Nature Publishing Group
DOI: 10.1038/s41588-019-0413-z

Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers

Autori: Sandra Schick, André F. Rendeiro, Kathrin Runggatscher, Anna Ringler, Bernd Boidol, Melanie Hinkel, Peter Májek, Loan Vulliard, Thomas Penz, Katja Parapatics, Christian Schmidl, Jörg Menche, Guido Boehmelt, Mark Petronczki, André C. Müller, Christoph Bock, Stefan Kubicek
Pubblicato in: Nature Genetics, Numero 51/9, 2019, Pagina/e 1399-1410, ISSN 1061-4036
Editore: Nature Publishing Group
DOI: 10.1038/s41588-019-0477-9

A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs

Autori: Enrico Girardi, Adrián César-Razquin, Sabrina Lindinger, Konstantinos Papakostas, Justyna Konecka, Jennifer Hemmerich, Stefanie Kickinger, Felix Kartnig, Bettina Gürtl, Kristaps Klavins, Vitaly Sedlyarov, Alvaro Ingles-Prieto, Giuseppe Fiume, Anna Koren, Charles-Hugues Lardeau, Richard Kumaran Kandasamy, Stefan Kubicek, Gerhard F. Ecker, Giulio Superti-Furga
Pubblicato in: Nature Chemical Biology, Numero 16/4, 2020, Pagina/e 469-478, ISSN 1552-4450
Editore: Nature Publishing Group
DOI: 10.1038/s41589-020-0483-3

PlateFlo – A software-controllable plate-scale perfusion system for culture of adherent cells

Autori: Robert Pazdzior; Stefan Kubicek
Pubblicato in: HardwareX, Numero e00222, 2021, ISSN 2468-0672
Editore: Elsevier
DOI: 10.1016/j.ohx.2021.e00222

Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time

Autori: Andreas Reicher, Anna Koren, Stefan Kubicek
Pubblicato in: Genome Research, Numero 30, 2020, Pagina/e 1846-1855, ISSN 1088-9051
Editore: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.261503.120

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