Magnetically Assisted Tissue Engineering Technologies for Tendon Regeneration

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Risultati finali

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Pubblicazioni

Contactless Resolution of Inflammatory Signals in Tailored Macrophage-Based Cell Therapeutics

Autori: Ana F. Almeida, Margarida S. Miranda, Adriana Vinhas, Márcia T. Rodrigues, Manuela E. Gomes
Pubblicato in: ACS Applied Materials & Interfaces, Numero 15, 2023, Pagina/e 50612-50625, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.2c22505

Biocompatible 3D-Printed Tendon/Ligament Scaffolds Based on Polylactic Acid/Graphite Nanoplatelet Composites

Autori: Magda Silva, Susana Gomes, Cátia Correia, Daniela Peixoto, Adriana Vinhas, Márcia T. Rodrigues, Manuela E. Gomes, José A. Covas, Maria C. Paiva, Natália M. Alves
Pubblicato in: Nanomaterials, Numero 13, 2025, Pagina/e 2518, ISSN 2079-4991
Editore: MDPI AG
DOI: 10.3390/nano13182518

Achilles tendinopathy

Autori: Andreas Traweger, Alex Scott, Michael Kjaer, Evi Wezenbeek, Rodrigo Scattone Silva, John G. Kennedy, James J. Butler, Manuel Gomez-Florit, Manuela E. Gomes, Jess G. Snedeker, Stephanie G. Dakin, Britt Wildemann
Pubblicato in: Nature Reviews Disease Primers, Numero 11, 2025, ISSN 2056-676X
Editore: Springer Science and Business Media LLC
DOI: 10.1038/s41572-025-00602-9

Magnetic Stimulation Drives Macrophage Polarization in Cell to–Cell Communication with IL-1β Primed Tendon Cells

Autori: Adriana Vinhas, Ana F. Almeida, Ana I. Gonçalves, Márcia T. Rodrigues, Manuela E. Gomes
Pubblicato in: International Journal of Molecular Sciences, Numero 21/15, 2020, Pagina/e 5441, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21155441

Remote triggering of TGF-β/Smad2/3 signaling in human adipose stem cells laden on magnetic scaffolds synergistically promotes tenogenic commitment

Autori: Ana M. Matos, Ana I. Gonçalves, Márcia T. Rodrigues, Margarida S. Miranda, Alicia J. El Haj, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Acta Biomaterialia, Numero 113, 2020, Pagina/e 488-500, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2020.07.009

Epitope‐Imprinted Nanoparticles as Transforming Growth Factor‐β3 Sequestering Ligands to Modulate Stem Cell Fate

Autori: Simão P. B. Teixeira, Rui M. A. Domingues, Pedro S. Babo, Dominika Berdecka, Margarida S. Miranda, Manuela E. Gomes, Nicholas A. Peppas, Rui L. Reis
Pubblicato in: Advanced Functional Materials, 2020, Pagina/e 2003934, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202003934

Therapeutic Effects of Platelet-Derived Extracellular Vesicles in a Bioengineered Tendon Disease Model

Autori: Rui Domingues; Isabel Calejo; Ana Graça; Manuela Gomes; Manuel Gomez-Florit
Pubblicato in: International Journal of Molecular Sciences; Volume 23; Numero 6; Pages: 2948, Numero 1, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23062948

Hierarchical Design of Tissue‐Mimetic Fibrillar Hydrogel Scaffolds

Autori: Alberto Pardo, Manuel Gomez‐Florit, Matthew D. Davidson, Meftune Özgen Öztürk‐Öncel, Rui M. A. Domingues, Jason A. Burdick, Manuela E. Gomes
Pubblicato in: Advanced Healthcare Materials, Numero 13, 2024, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202303167

Epitope-imprinted polymers: design principles of synthetic binding partners for natural biomacromolecules

Autori: Teixeira, Simão P. B.,Reis, R. L.,Peppas, Nicholas A.,Gomes, Manuela E.
Pubblicato in: Science Advances, 2021, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abi9884

Guiding Stem Cell Tenogenesis by Modulation of Growth Factor Signaling and Cell‐Scale Biophysical Cues in Bioengineered Constructs

Autori: Simão P. B. Teixeira, Alberto Pardo, Syeda M. Bakht, Manuel Gomez‐Florit, Rui L. Reis, Manuela E. Gomes, Rui M. A. Domingues
Pubblicato in: Advanced Functional Materials, Numero 34, 2024, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202312961

Writing 3D <i>In Vitro</i> Models of Human Tendon within a Biomimetic Fibrillar Support Platform

Autori: Rosa F. Monteiro, Syeda M. Bakht, Manuel Gomez-Florit, Fernanda C. Stievani, Ana L. G. Alves, Rui L. Reis, Manuela E. Gomes, Rui M. A. Domingues
Pubblicato in: ACS Applied Materials & Interfaces, Numero 15, 2023, Pagina/e 50598-50611, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.2c22371

Controlling the fate of regenerative cells with engineered platelet-derived extracellular vesicles

Autori: Ana L. Graça; Manuel Gómez-Florit; Hugo Osório; Márcia T. Rodrigues; Rui M. A. Domingues; Rui L. Reis; Manuela E. Gomes
Pubblicato in: Nanoscale, Numero 4, 2022, ISSN 2040-3372
Editore: Royal Society of Chemistry
DOI: 10.1039/d1nr08108j

Bioengineered 3D living fibers as in vitro human tissue models of tendon physiology and pathology

Autori: Isabel Calejo; Claudia J. Labrador‐Rached; Manuel Gomez‐Florit; Denitsa Docheva; Rui L. Reis; Rui M. A. Domingues; Manuela E. Gomes
Pubblicato in: Advanced Healthcare Materials, Numero 2, 2022, ISSN 2192-2659
Editore: World Scientific
DOI: 10.1002/adhm.202102863

Human Tendon‐on‐Chip: Unveiling the Effect of Core Compartment‐T Cell Spatiotemporal Crosstalk at the Onset of Tendon Inflammation

Autori: Syeda M. Bakht, Alberto Pardo, Manuel Gomez‐Florit, David Caballero, Subhas C. Kundu, Rui L. Reis, Rui M. A. Domingues, Manuela E. Gomes
Pubblicato in: Advanced Science, Numero 11, 2025, ISSN 2198-3844
Editore: Wiley
DOI: 10.1002/advs.202401170

Magnetic biomaterials and nano-instructive tools as mediators of tendon mechanotransduction

Autori: Ana M. Matos, Ana I. Gonçalves, Alicia J. El Haj, Manuela E. Gomes
Pubblicato in: Nanoscale Advances, Numero 2/1, 2020, Pagina/e 140-148, ISSN 2516-0230
Editore: The Royal Society of Chemistry
DOI: 10.1039/c9na00615j

Engineering next-generation bioinks with nanoparticles: moving from reinforcement fillers to multifunctional nanoelements.

Autori: Syeda Mahwish Bakht; Alberto Pardo; Alberto Pardo; Manuel Gómez-Florit; Rui L. Reis; Rui M. A. Domingues; Manuela E. Gomes
Pubblicato in: Journal of Materials Chemistry B, Numero 2, 2021, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d1tb00717c

The impact of cryopreservation in signature markers and immunomodulatory profile of tendon and ligament derived cells

Autori: Ana I. Gonçalves; Adriana Vinhas; Márcia T. Rodrigues; Manuela E. Gomes
Pubblicato in: Journal of Cellular Physiology, Numero 6, 2021, ISSN 1097-4652
Editore: Wiley
DOI: 10.1002/jcp.30540

Biomaterials for Sequestration of Growth Factors and Modulation of Cell Behavior

Autori: Simão P. B. Teixeira, Rui M. A. Domingues, Mariya Shevchuk, Manuela E. Gomes, Nicholas A. Peppas, Rui L. Reis
Pubblicato in: Advanced Functional Materials, Numero 30/44, 2020, Pagina/e 1909011, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201909011

Magnetic responsive materials modulate the inflammatory profile of IL-1β conditioned tendon cells

Autori: A. Vinhas, M.T. Rodrigues, A.I. Gonçalves, R.L. Reis, M.E. Gomes
Pubblicato in: Acta Biomaterialia, Numero 117, 2020, Pagina/e 235-245, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2020.09.028

Injectable and Magnetic Responsive Hydrogels with Bioinspired Ordered Structures

Autori: Sandra Araújo-Custódio, Manuel Gomez-Florit, Ana R. Tomás, Bárbara B. Mendes, Pedro S. Babo, Suzanne M. Mithieux, Anthony Weiss, Rui M. A. Domingues, Rui L. Reis, Manuela E. Gomes
Pubblicato in: ACS Biomaterials Science & Engineering, Numero 5/3, 2019, Pagina/e 1392-1404, ISSN 2373-9878
Editore: American Chemical Society
DOI: 10.1021/acsbiomaterials.8b01179

Tropoelastin-Coated Tendon Biomimetic Scaffolds Promote Stem Cell Tenogenic Commitment and Deposition of Elastin-Rich Matrix

Autori: Helena Almeida, Rui M. A. Domingues, Suzanne M. Mithieux, Ricardo A. Pires, Ana I. Gonçalves, Manuel Gómez-Florit, Rui L. Reis, Anthony S. Weiss, Manuela E. Gomes
Pubblicato in: ACS Applied Materials & Interfaces, Numero 11/22, 2019, Pagina/e 19830-19840, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.9b04616

Platelet-Derived Extracellular Vesicles Promote Tenogenic Differentiation of Stem Cells on Bioengineered Living Fibers

Autori: Ana L. Graça, Rui M. A. Domingues, Manuel Gomez-Florit, Manuela E. Gomes
Pubblicato in: International Journal of Molecular Sciences, Numero 24, 2023, Pagina/e 3516, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24043516

Advancements in dental bioreactor design: A comprehensive approach for application in dentistry

Autori: Esteban Astudillo-Ortiz, Pedro S. Babo, Ana I. Gonçalves, Manuela E. Gomes
Pubblicato in: MethodsX, Numero 13, 2025, Pagina/e 103026, ISSN 2215-0161
Editore: Elsevier BV
DOI: 10.1016/j.mex.2024.103026

Biphasic Hydrogels Integrating Mineralized and Anisotropic Features for Interfacial Tissue Engineering

Autori: Mari Carmen Echave, Rui M. A. Domingues, Manuel Gómez-Florit, José Luis Pedraz, Rui L. Reis, Gorka Orive, Manuela E. Gomes
Pubblicato in: ACS Applied Materials & Interfaces, Numero 11/51, 2019, Pagina/e 47771-47784, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.9b17826

Injectable hyaluronic acid and platelet lysate-derived granular hydrogels for biomedical applications

Autori: Bárbara B. Mendes, Andrew C. Daly, Rui L. Reis, Rui M.A. Domingues, Manuela E. Gomes, Jason A. Burdick
Pubblicato in: Acta Biomaterialia, Numero 119, 2021, Pagina/e 101-113, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2020.10.040

Intrinsically Bioactive Cryogels Based on Platelet Lysate Nanocomposites for Hemostasis Applications

Autori: Bárbara B. Mendes, Manuel Gómez-Florit, Ana C. Araújo, Justina Prada, Pedro S. Babo, Rui M. A. Domingues, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Biomacromolecules, Numero 21/9, 2020, Pagina/e 3678-3692, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.0c00787

Using Hybrid Nanoplatforms to Combine Traditional Anti-Inflammatory Drug Delivery with RNA-Based Therapeutics for Macrophage Reprograming

Autori: Ana F. Almeida, Margarida S. Miranda, Rui L. Reis, Manuela E. Gomes, Márcia T. Rodrigues
Pubblicato in: International Journal of Molecular Sciences, Numero 25, 2025, Pagina/e 10693, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms251910693

3D bioprinting of miniaturized tissues embedded in self-assembled nanoparticle-based fibrillar platforms

Autori: Syeda Mahwish Bakht; Manuel Gómez-Florit; Tara Helena Lamers; Rui L. Reis; Rui M. A. Domingues; Manuela E. Gomes
Pubblicato in: Advanced Functional Materials, Numero 1, 2021, ISSN 1616-3028
Editore: Wiley
DOI: 10.1002/adfm.202104245

Magneto-mechanical actuation of magnetic responsive fibrous scaffolds boosts tenogenesis of human adipose stem cells

Autori: Ana R. Tomás, Ana I. Gonçalves, Elvira Paz, Paulo Freitas, Rui M. A. Domingues, Manuela E. Gomes
Pubblicato in: Nanoscale, Numero 11/39, 2019, Pagina/e 18255-18271, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/c9nr04355a

Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose‐derived stem cells

Autori: Ana I. Gonçalves, Dominika Berdecka, Márcia T. Rodrigues, Aysegul Dede Eren, Jan Boer, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Journal of Tissue Engineering and Regenerative Medicine, Numero 13/12, 2019, Pagina/e 2204-2217, ISSN 1932-6254
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/term.2967

Human platelet lysate-based nanocomposite bioink for bioprinting hierarchical fibrillar structures

Autori: Bárbara B Mendes, Manuel Gómez-Florit, Alex G Hamilton, Michael S Detamore, Rui M A Domingues, Rui L Reis, Manuela E Gomes
Pubblicato in: Biofabrication, Numero 12/1, 2020, Pagina/e 015012, ISSN 1758-5090
Editore: IOP Publishing
DOI: 10.1088/1758-5090/ab33e8

A Textile Platform Using Continuous Aligned and Textured Composite Microfibers to Engineer Tendon‐to‐Bone Interface Gradient Scaffolds

Autori: Isabel Calejo, Raquel Costa‐Almeida, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Advanced Healthcare Materials, Numero 8/15, 2019, Pagina/e 1900200, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201900200

Mesenchymal Stem Cells Empowering Tendon Regenerative Therapies

Autori: Raquel Costa-Almeida, Isabel Calejo, Manuela E. Gomes
Pubblicato in: International Journal of Molecular Sciences, Numero 20/12, 2019, Pagina/e 3002, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20123002

A Physiology-Inspired Multifactorial Toolbox in Soft-to-Hard Musculoskeletal Interface Tissue Engineering

Autori: Isabel Calejo, Raquel Costa-Almeida, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Trends in Biotechnology, Numero 38/1, 2020, Pagina/e 83-98, ISSN 0167-7799
Editore: Elsevier BV
DOI: 10.1016/j.tibtech.2019.06.003

Exploring platelet lysate hydrogel-coated suture threads as biofunctional composite living fibers for cell delivery in tissue repair

Autori: Raquel Costa-Almeida, Isabel Calejo, Roberta Altieri, Rui M A Domingues, Emanuele Giordano, Rui L Reis, Manuela E Gomes
Pubblicato in: Biomedical Materials, Numero 14/3, 2019, Pagina/e 034104, ISSN 1748-605X
Editore: IOP Publishing
DOI: 10.1088/1748-605x/ab0de6

Enthesis Tissue Engineering: Biological Requirements Meet at the Interface

Autori: Isabel Calejo, Raquel Costa-Almeida, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Tissue Engineering Part B: Reviews, Numero 25/4, 2019, Pagina/e 330-356, ISSN 1937-3368
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ten.teb.2018.0383

The tendon microenvironment: Engineered in vitro models to study cellular crosstalk

Autori: Manuel Gomez-Florit, Claudia J. Labrador-Rached, Rui M.A. Domingues, Manuela E. Gomes
Pubblicato in: Advanced Drug Delivery Reviews, Numero 185, 2022, Pagina/e 114299, ISSN 0169-409X
Editore: Elsevier BV
DOI: 10.1016/j.addr.2022.114299

A dive into the bath: embedded 3D bioprinting of freeform <i>in vitro</i> models

Autori: M. Özgen Öztürk-Öncel, Baltazar Hiram Leal-Martínez, Rosa F. Monteiro, Manuela E. Gomes, Rui M. A. Domingues
Pubblicato in: Biomaterials Science, Numero 11, 2024, Pagina/e 5462-5473, ISSN 2047-4830
Editore: Royal Society of Chemistry
DOI: 10.1039/d3bm00626c

Prospects of magnetically based approaches addressing inflammation in tendon tissues

Autori: Adriana Vinhas, Ana F. Almeida, Márcia T. Rodrigues, Manuela E. Gomes
Pubblicato in: Advanced Drug Delivery Reviews, Numero 196, 2023, Pagina/e 114815, ISSN 0169-409X
Editore: Elsevier BV
DOI: 10.1016/j.addr.2023.114815

Texturing Hierarchical Tissues by Gradient Assembling of Microengineered Platelet‐Lysates Activated Fibers

Autori: Isabel Calejo; Rui L. Reis; Rui M. A. Domingues; Manuela E. Gomes
Pubblicato in: Advanced Healthcare Materials, Numero 8, 2021, ISSN 2192-2659
Editore: World Scientific
DOI: 10.1002/adhm.202102076

3D BIOMIMETIC CONSTRUCTS STEER STEM CELL COMMITMENT BY SYNERGISTIC MODULATION OF BIOPHYSICAL CUES AND GROWTH FACTOR SIGNALLING

Autori: S.P.B. Teixeira, A. Pardo, S.M. Bakht, M. Gomez-Florit, R.L. Reis, M.E. Gomes, R.M.A. Domingues
Pubblicato in: Orthopaedic Proceedings, Numero 106-B, 2024, Pagina/e 13-13, ISSN 1358-992X
Editore: British Editorial Society of Bone & Joint Surgery
DOI: 10.1302/1358-992x.2024.1.013

Magnetic Micellar Nanovehicles: Prospects of Multifunctional Hybrid Systems for Precision Theranostics

Autori: Margarida S. Miranda, Ana F. Almeida, Manuela E. Gomes, and Márcia T. Rodrigues
Pubblicato in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911793

Cellulose nanocrystals of variable sulfation degrees can sequester specific platelet lysate-derived biomolecules to modulate stem cell response

Autori: Bárbara B. Mendes, Manuel Gómez-Florit, Hugo Osório, Adriana Vilaça, Rui M. A. Domingues, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Chemical Communications, Numero 56/50, 2020, Pagina/e 6882-6885, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/D0CC01850C

Magnetically-assisted 3D bioprinting of anisotropic tissue-mimetic constructs

Autori: Pardo A., Bakht S. M., Gomez-Florit M., Rial R., Monteiro R., Teixeira S. P. B., Taboada P., Reis R. L., Domingues R. M. A., Gomes M. E.
Pubblicato in: Advanced Functional Materials, 2022, ISSN 1616-3028
Editore: Wiley
DOI: 10.1002/adfm.202208940

Controlling Macrophage Polarization to Modulate Inflammatory Cues Using Immune-Switch Nanoparticles

Autori: Ana F. Almeida, Margarida S. Miranda, Adriana Vinhas, Ana I. Gonçalves, Manuela E. Gomes, Márcia T. Rodrigues
Pubblicato in: International Journal of Molecular Sciences, Numero 23, 2024, Pagina/e 15125, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232315125

Immunomodulatory Behavior of Tendon Magnetic Cell Sheets can be Modulated in Hypoxic Environments under Magnetic Stimulus

Autori: Adriana Vinhas, Márcia T. Rodrigues, Ana I. Gonçalves, Manuela E. Gomes
Pubblicato in: ACS Applied Materials & Interfaces, Numero 16, 2024, Pagina/e 44440-44450, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.4c08154

Platelet-rich Blood Derivatives for Tendon Regeneration.

Autori: Raquel Costa-Almeida; Pedro S. Babo; Rui L. Reis; Manuela E. Gomes
Pubblicato in: Journal of the American Academy of Orthopaedic Surgeons, Numero 19405480, 2020, ISSN 1940-5480
Editore: Lippincott, Williams & Wilkins
DOI: 10.5435/jaaos-d-18-00638

Magnetic Nanocomposite Hydrogels for Tissue Engineering: Design Concepts and Remote Actuation Strategies to Control Cell Fate

Autori: Alberto Pardo; Manuel Gómez-Florit; Silvia Barbosa; Pablo Taboada; Rui M. A. Domingues; Manuela E. Gomes
Pubblicato in: ACS Nano, Numero 7, 2021, ISSN 1936-086X
Editore: American Chemical Society
DOI: 10.1021/acsnano.0c08253

Pulsed Electromagnetic Field Modulates Tendon Cells Response in IL‐1β‐Conditioned Environment

Autori: Adriana Vinhas, Márcia T. Rodrigues, Ana I. Gonçalves, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Journal of Orthopaedic Research, Numero 38/1, 2019, Pagina/e 160-172, ISSN 0736-0266
Editore: Elsevier BV
DOI: 10.1002/jor.24538

Human tendon-derived cell sheets created by magnetic force-based tissue engineering hold tenogenic and immunomodulatory potential

Autori: AdrianaVinhas, Ana I.Gonçalves, Márcia T.Rodrigues, Manuela E.Gomes
Pubblicato in: Acta Biomaterialia, 2021, ISSN 1878-7568
Editore: Elsevier
DOI: 10.1016/j.actbio.2021.06.036

Magnetic triggers in biomedical applications - prospects for contact free cell sensing and guidance.

Autori: Ana Filipa Martins Almeida; Adriana Vinhas; Ana I. Gonçalves; Margarida S. Miranda; Márcia T. Rodrigues; Manuela E. Gomes
Pubblicato in: Journal of Materials Chemistry B, Numero 10, 2021, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d0tb02474k

Natural-Based Hydrogels for Tissue Engineering Applications

Autori: Gómez-Florit M., Pardo A., Domingues R. M. A., Graça A. L., Babo P. S., Reis R. L., Gomes M. E.
Pubblicato in: Molecules, 2020, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25245858

In vitro temporal HIF‐mediated deposition of osteochondrogenic matrix governed by hypoxia and osteogenic factors synergy

Autori: Isabel Calejo, Raquel Costa‐Almeida, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Journal of Cellular Physiology, 2020, ISSN 0021-9541
Editore: John Wiley & Sons Inc.
DOI: 10.1002/jcp.30138

Xeno-free bioengineered human skeletal muscle tissue using human platelet lysate-based hydrogels

Autori: Juan M. Fernandez-Costa; Rui Domingues; Javier Ramon; Xiomara Fernández-Garibay; Manuela Gomes; Manuel Gomez-Florit
Pubblicato in: Biofabrication, Numero 2, 2022, ISSN 1758-5090
Editore: IOP Publishing
DOI: 10.1088/1758-5090/ac8dc8

Multiscale Multifactorial Approaches for Engineering Tendon Substitutes

Autori: Ana I. Gonçalves, Márcia T. Rodrigues, Ana M. Matos, Helena Almeida, Manuel Gómez-Florit, Rui M. A. Domingues, Manuela E. Gomes
Pubblicato in: Organ Tissue Engineering, 2020, Pagina/e 1-24, ISBN 978-3-030-18512-1
Editore: Springer International Publishing
DOI: 10.1007/978-3-030-18512-1_8-1

Bioinspired materials and tissue engineering approaches applied to the regeneration of musculoskeletal tissues

Autori: Márcia T. Rodrigues, Ana I. Gonçalves, Pedro S. Babo, Manuel Gomez-Florit, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Engineering Strategies for Regenerative Medicine, 2020, Pagina/e 73-105, ISBN 9780128162217
Editore: Elsevier
DOI: 10.1016/b978-0-12-816221-7.00003-3

Future Directions: What the Future Holds for TERM

Autori: Márcia T. Rodrigues, Rui M.A. Domingues, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Reference Module in Biomedical Sciences, 2019, ISBN 9780128012383
Editore: Elsevier
DOI: 10.1016/b978-0-12-801238-3.11287-5

Natural Materials

Autori: Manuel Gómez-Florit, Rui M.A. Domingues, Syeda Mahwish Bakht, Bárbara B. Mendes, Rui L. Reis, Manuela E. Gomes
Pubblicato in: Biomaterials Science, 2020, Pagina/e 361-375, ISBN 9780128161371
Editore: Elsevier
DOI: 10.1016/b978-0-12-816137-1.00026-x

Cellular Complexity at the Interface: Challenges in Enthesis Tissue Engineering

Autori: Isabel Calejo, Raquel Costa-Almeida, Manuela E. Gomes
Pubblicato in: Cell Biology and Translational Medicine, Volume 5 - Stem Cells: Translational Science to Therapy, Numero 1144, 2019, Pagina/e 71-90, ISBN 978-3-030-17588-7
Editore: Springer International Publishing
DOI: 10.1007/5584_2018_307

Exploring Stem Cells and Inflammation in Tendon Repair and Regeneration

Autori: A. Vinhas, M. T. Rodrigues, M. E. Gomes
Pubblicato in: Cell Biology and Translational Medicine, Volume 2 - Approaches for Diverse Diseases and Conditions, Numero 1089, 2018, Pagina/e 37-46, ISBN 978-3-030-04169-4
Editore: Springer International Publishing
DOI: 10.1007/5584_2018_258

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