Epigenetic and metabolic regulation of endothelial heterogeneity

Pubblicazioni

Control of endothelial quiescence by FOXO-regulated metabolites

Autori: Jorge Andrade, Chenyue Shi, Ana S. H. Costa, Jeongwoon Choi, Jaeryung Kim, Anuradha Doddaballapur, Toshiya Sugino, Yu Ting Ong, Marco Castro, Barbara Zimmermann, Manuel Kaulich, Stefan Guenther, Kerstin Wilhelm, Yoshiaki Kubota, Thomas Braun, Gou Young Koh, Ana Rita Grosso, Christian Frezza, Michael Potente
Pubblicato in: Nature Cell Biology, Numero 23/4, 2021, Pagina/e 413-423, ISSN 1465-7392
Editore: Nature Publishing Group
DOI: 10.1038/s41556-021-00637-6

Post-myocardial infarction heart failure dysregulates the bone vascular niche

Autori: Jedrzej Hoffmann, Guillermo Luxán, Wesley Tyler Abplanalp, Simone-Franziska Glaser, Tina Rasper, Ariane Fischer, Marion Muhly-Reinholz, Michael Potente, Birgit Assmus, David John, Andreas Michael Zeiher & Stefanie Dimmeler
Pubblicato in: Nature Communications, Numero 12(1), 2021, Pagina/e 3964, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-24045-4

Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine

Autori: Fan Wu, Xiang Li, Mario Looso, Hang Liu, Dong Ding, Stefan Günther, Carsten Kuenne, Shuya Liu, Norbert Weissmann, Thomas Böttger, Ann Atzberger, Saeed Kolahian, Harald Renz, Stefan Offermanns, Ulrich Gärtner, Michael Potente, Yonggang Zhou, Xuejun Yuan, Thomas Braun
Pubblicato in: Nature Genetics, 2022, ISSN 1061-4036
Editore: Nature Publishing Group
DOI: 10.1038/s41588-022-01252-3

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

Autori: Christian SM Helker, Jean Eberlein, Kerstin Wilhelm, Toshiya Sugino, Julian Malchow, Annika Schuermann, Stefan Baumeister, Hyouk-Bum Kwon, Hans-Martin Maischein, Michael Potente, Wiebke Herzog, Didier YR Stainier
Pubblicato in: eLife, Numero 9, 2020, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.55589

Arterialization requires the timely suppression of cell growth

Autori: Wen Luo, Irene Garcia-Gonzalez, Macarena Fernández-Chacón, Verónica Casquero-Garcia, Maria S. Sanchez-Muñoz, Severin Mühleder, Lourdes Garcia-Ortega, Jorge Andrade, Michael Potente, Rui Benedito
Pubblicato in: Nature, Numero 589/7842, 2021, Pagina/e 437-441, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-020-3018-x

Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

Autori: Akihiro Kaneshige, Takayuki Kaji, Lidan Zhang, Hayato Saito, Ayasa Nakamura, Tamaki Kurosawa, Madoka Ikemoto-Uezumi, Kazutake Tsujikawa, Shigeto Seno, Masatoshi Hori, Yasuyuki Saito, Takashi Matozaki, Kazumitsu Maehara, Yasuyuki Ohkawa, Michael Potente, Shuichi Watanabe, Thomas Braun, Akiyoshi Uezumi, So-Ichiro Fukada
Pubblicato in: Cell Stem Cell, Numero 29(2), 2022, Pagina/e 265-280.e6, ISSN 1934-5909
Editore: Cell Press
DOI: 10.1016/j.stem.2021.11.003

Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics

Autori: Francesca Ferrante, Benedetto Daniele Giaimo, Tobias Friedrich, Toshiya Sugino, Daniel Mertens, Sabrina Kugler, Bernd Martin Gahr, Steffen Just, Leiling Pan, Marek Bartkuhn, Michael Potente , Franz Oswald, Tilman Borggrefe
Pubblicato in: Cell Death & Disease, Numero 13(7), 2022, Pagina/e 600, ISSN 2041-4889
Editore: Nature Publishing Group
DOI: 10.1038/s41419-022-05052-9

Metabolic modulation regulates cardiac wall morphogenesis in zebrafish

Autori: Ryuichi Fukuda, Alla Aharonov, Yu Ting Ong, Oliver A Stone, Mohamed El-Brolosy, Hans-Martin Maischein, Michael Potente, Eldad Tzahor, Didier YR Stainier
Pubblicato in: eLife, Numero 8, 2019, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.50161

Deubiquitinase USP10 regulates Notch signaling in the endothelium

Autori: Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I, Potente M
Pubblicato in: Science, Numero 364/6436, 2019, Pagina/e 364(6436):188-193, ISSN 0036-8075
Editore: American Association for the Advancement of Science

Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells

Autori: Oliver A. Stone, Mohamed El-Brolosy, Kerstin Wilhelm, Xiaojing Liu, Ana M. Romão, Elisabetta Grillo, Jason K. H. Lai, Stefan Günther, Sylvia Jeratsch, Carsten Kuenne, I-Ching Lee, Thomas Braun, Massimo M. Santoro, Jason W. Locasale, Michael Potente, Didier Y. R. Stainier
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-06406-8

aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability

Autori: Meghan Riddell, Akiko Nakayama, Takao Hikita, Fatemeh Mirzapourshafiyi, Takuji Kawamura, Ayesha Pasha, Mengnan Li, Mikio Masuzawa, Mario Looso, Tim Steinbacher, Klaus Ebnet, Michael Potente, Tomonori Hirose, Shigeo Ohno, Ingrid Fleming, Stefan Gattenlöhner, Phyu P. Aung, Thuy Phung, Osamu Yamasaki, Teruki Yanagi, Hiroshi Umemura, Masanori Nakayama
Pubblicato in: Nature Communications, Numero 9/1, 2018, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-018-07739-0

A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth

Autori: Yu Ting Ong, Jorge Andrade, Max Armbruster, Chenyue Shi, Marco Castro, Ana S H Costa, Toshiya Sugino, Guy Eelen, Barbara Zimmermann, Kerstin Wilhelm, Joseph Lim, Shuichi Watanabe, Stefan Guenther, Andre Schneider, Francesca Zanconato, Manuel Kaulich, Duojia Pan, Thomas Braun, Holger Gerhardt, Alejo Efeyan, Peter Carmeliet, Stefano Piccolo, Ana Rita Grosso, Michael Potente
Pubblicato in: Nature Metabolism, Numero 4(6), 2022, Pagina/e 672-682, ISSN 2522-5812
Editore: Nature Publishing Group
DOI: 10.1038/s42255-022-00584-y

YAP and TAZ protect against white adipocyte cell death during obesity

Autori: Lei Wang, ShengPeng Wang, Yue Shi, Rui Li, Stefan Günther, Yu Ting Ong, Michael Potente, Zuyi Yuan, Enqi Liu, Stefan Offermanns
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-19229-3

Regional specialization and fate specification of bone stromal cells in skeletal development

Autori: Kishor K Sivaraj, Hyun-Woo Jeong, Backialakshmi Dharmalingam, Dagmar Zeuschner, Susanne Adams, Michael Potente, Ralf H Adams
Pubblicato in: Cell Reports, Numero 36(2), 2021, Pagina/e 109352, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2021.109352

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Autori: Aileen A. Ren, Daniel A. Snellings, Yourong S. Su, Courtney C. Hong, Marco Castro, Alan T. Tang, Matthew R. Detter, Nicholas Hobson, Romuald Girard, Sharbel Romanos, Rhonda Lightle, Thomas Moore, Robert Shenkar, Christian Benavides, M. Makenzie Beaman, Helge Müller-Fielitz, Mei Chen, Patricia Mericko, Jisheng Yang, Derek C. Sung, Michael T. Lawton, J. Michael Ruppert, Markus Schwaninger, Jakob K
Pubblicato in: Nature, Numero 594(7862), 2021, Pagina/e 271-276, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-021-03562-8

Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses

Autori: Andreas W Heumüller, Alisha N Jones, André Mourão, Marius Klangwart, Chenyue Shi, Ilka Wittig, Ariane Fischer, Marion Muhly-Reinholz, Giulia K Buchmann, Christoph Dieterich, Michael Potente, Thomas Braun, Phillip Grote, Nicolas Jaé, Michael Sattler, Stefanie Dimmeler
Pubblicato in: Circulation Research, Numero 130(1), 2022, Pagina/e 67-79, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.121.320029

Inhibition of fatty acid oxidation enables heart regeneration in adult mice

Autori: Xiang Li, Fan Wu, Stefan Günther, Mario Looso, Carsten Kuenne, Ting Zhang, Marion Wiesnet, Stephan Klatt, Sven Zukunft, Ingrid Fleming, Gernot Poschet, Astrid Wietelmann, Ann Atzberger, Michael Potente, Xuejun Yuan, Thomas Braun
Pubblicato in: Nature, Numero 2023 Oct;622(7983), 2023, Pagina/e 619-626, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-023-06585-5

Top-NOTCH Regulation of Cardiac Metabolism

Autori: Radiance Lim, Michael Potente
Pubblicato in: Circulation, Numero 137/24, 2018, Pagina/e 2609-2612, ISSN 0009-7322
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.118.033669

Endothelial metabolism—more complex (III) than previously thought

Autori: Jorge Andrade, Michael Potente
Pubblicato in: Nature Metabolism, 2019, ISSN 2522-5812
Editore: Springer Nature
DOI: 10.1038/s42255-018-0019-2

Endothelial Cells Don’t Waste: Endothelial-Derived Lactate Boosts Muscle Regeneration

Autori: Marco Castro, Jorge Andrade, Michael Potente
Pubblicato in: Developmental Cell, Numero 54/2, 2020, Pagina/e 137-139, ISSN 1534-5807
Editore: Cell Press
DOI: 10.1016/j.devcel.2020.06.023

The blood-brain barrier-a metabolic ecosystem

Autori: Marco Castro, Michael Potente
Pubblicato in: EMBO Journal, Numero 41(9), 2022, Pagina/e e111189, ISSN 0261-4189
Editore: Nature Publishing Group
DOI: 10.15252/embj.2022111189

È in corso la ricerca di dati su OpenAIRE...

Pubblicazioni

Condividi questa pagina

Scarica