InSilc: In-silico trials for drug-eluting BVS design, development and evaluation

Resultado final

Dissemination plan and activities v2

Report summarising the dissemination strategy and activities of the InSilc 2nd year

Project website, poster, flyer and social media

Report presenting the InSilc website, poster, flyer and social media accounts

Quality Assurance plan

Report on the Quality Assurance plan

Dissemination plan and activities v3

Report summarising the dissemination strategy and activities of the InSilc 3rd year

Project handbook

Report on the project handbook

Final press release

Report of the InSilc final press release

Dissemination plan and activities v1

Report summarising the dissemination strategy and activities of the InSilc 1st year

Publicaciones

A Novel Approach to Generate a Virtual Population of Human Coronary Arteries for In Silico Clinical Trials of Stent Design

Autores: Dimitrios Pleouras, Antonis Sakellarios, George Rigas, Georgia S. Karanasiou, Panagiota Tsompou, Gianna Karanasiou, Vassiliki Kigka, Savvas Kyriakidis, Vasileios Pezoulas, George Gois, Nikolaos Tachos, Aidonis Ramos, Gualtiero Pelosi, Silvia Rocchiccioli, Lampros Michalis, Dimitrios I. Fotiadis
Publicado en: IEEE Open Journal of Engineering in Medicine and Biology, Edición 2, 2021, Página(s) 201-209, ISSN 2644-1276
Editor: IEEE
DOI: 10.1109/ojemb.2021.3082328

From the real device to the digital twin: A coupled experimental-numerical strategy to investigate a novel bioresorbable vascular scaffold

Autores: Luca Antonini, Francesca Berti, Benedetta Isella, Dipok Hossain, Lorenzo Mandelli, Giancarlo Pennati, Lorenza Petrini
Publicado en: PLOS ONE, Edición 16/6, 2021, Página(s) e0252788, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0252788

Modulated molecular markers of restenosis and thrombosis by in-vitro vascular cells exposed to bioresorbable scaffolds

Autores: F Vozzi, A Cecchettini, M Cabiati, Fornaro Mg, P Aretini, S Del Ry, S Rocchiccioli, G Pelosi
Publicado en: Biomedical Materials, Edición 16/4, 2021, Página(s) 045039, ISSN 1748-6041
Editor: Institute of Physics Publishing
DOI: 10.1088/1748-605x/ac0401

Non-Invasive Prediction of Site-Specific Coronary Atherosclerotic Plaque Progression using Lipidomics, Blood Flow, and LDL Transport Modeling

Autores: Antonis I. Sakellarios, Panagiota Tsompou, Vassiliki Kigka, Panagiotis Siogkas, Savvas Kyriakidis, Nikolaos Tachos, Georgia Karanasiou, Arthur Scholte, Alberto Clemente, Danilo Neglia, Oberdan Parodi, Juhani Knuuti, Lampros K. Michalis, Gualtiero Pelosi, Silvia Rocchiccioli, Dimitrios I. Fotiadis
Publicado en: Applied Sciences, Edición 11/5, 2021, Página(s) 1976, ISSN 2076-3417
Editor: MDPI
DOI: 10.3390/app11051976

Physical and mechanical degradation behaviour of semi-crystalline PLLA for bioresorbable stent applications

Autores: Katarzyna Polak-Kraśna, Ali Reza Abaei, Reyhaneh Neghabat Shirazi, Eoin Parle, Oliver Carroll, William Ronan, Ted J. Vaughan
Publicado en: Journal of the Mechanical Behavior of Biomedical Materials, Edición 118, 2021, Página(s) 104409, ISSN 1751-6161
Editor: Elsevier BV
DOI: 10.1016/j.jmbbm.2021.104409

Validation of the computational model of a coronary DES delivery system: a fundamental step towards in-silico clinical trials

Autores: Antonini, Luca; Mandelli, Lorenzo; Berti, Francesca; Pennati, Giancarlo; Petrini, Lorenza
Publicado en: Journal of the Mechanical Behavior of Biomedical Materials, 2021, ISSN 1751-6161
Editor: Elsevier BV

In vitro and in silico testing of partially and fully bioresorbable vascular scaffold

Autores: Nenad Filipovic, Dalibor Nikolic, Velibor Isailovic, Miljan Milosevic, Vladimir Geroski, Georgia Karanasiou, Martin Fawdry, Aiden Flanagan, Dimitrios Fotiadis, Milos Kojic
Publicado en: Journal of Biomechanics, Edición 115, 2021, Página(s) 110158, ISSN 0021-9290
Editor: Elsevier BV
DOI: 10.1016/j.jbiomech.2020.110158

Multimodal Loading Environment Predicts Bioresorbable Vascular Scaffolds’ Durability

Autores: Pei-Jiang Wang, Francesca Berti, Luca Antonini, Farhad Rikhtegar Nezami, Lorenza Petrini, Francesco Migliavacca, Elazer R. Edelman
Publicado en: Annals of Biomedical Engineering, Edición 49/5, 2021, Página(s) 1298-1307, ISSN 0090-6964
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10439-020-02673-z

Population‐specific modelling of between/within‐subject flow variability in the carotid arteries of the elderly

Autores: Toni Lassila, Ali Sarrami‐Foroushani, SeyedMostafa Hejazi, Alejandro F. Frangi
Publicado en: International Journal for Numerical Methods in Biomedical Engineering, Edición 36/1, 2020, ISSN 2040-7939
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.3271

Is modeling stents still an important issue?

Autores: Francesco Migliavacca
Publicado en: Procedia Structural Integrity, Edición 15, 2019, Página(s) 46-50, ISSN 2452-3216
Editor: ELSEVIER
DOI: 10.1016/j.prostr.2019.07.009

A computational model for prediction of clot platelet content in flow-diverted intracranial aneurysms

Autores: Sarrami-Foroushani, Ali; Lassila, Toni; Hejazi, Seyed Mostafa; Nagaraja, Sanjoy; Bacon, Andrew; Frangi, Alejandro F.
Publicado en: Journal of Biomechanics, 2019, ISSN 0021-9290
Editor: Elsevier BV
DOI: 10.5281/zenodo.2671637

Three-dimensional reconstruction and NURBS-based structured meshing of coronary arteries from the conventional X-ray angiography projection images

Autores: Arso M. Vukicevic, Serkan Çimen, Nikola Jagic, Gordana Jovicic, Alejandro F. Frangi, Nenad Filipovic
Publicado en: Scientific Reports, Edición 8/1, 2018, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-018-19440-9

Impact of bioresorbable scaffold design characteristics on local haemodynamic forces: an ex vivo assessment with computational fluid dynamics simulations

Autores: Imane Tarrahi, Monika Colombo, Eline M.J. Hartman, Maria Natalia Tovar Forero, Ryo Torii, Claudio Chiastra, Joost Daemen, Frank J.H. Gijsen
Publicado en: EuroIntervention, Edición 16/11, 2020, Página(s) e930-e937, ISSN 1969-6213
Editor: EuroIntervention
DOI: 10.4244/eij-d-19-00657

Non-intrusive and semi-intrusive uncertainty quantification of a multiscale in-stent restenosis model

Autores: Dongwei Ye, Anna Nikishova, Lourens Veen, Pavel Zun, Alfons G. Hoekstra
Publicado en: Reliability Engineering & System Safety, Edición 214, 2021, Página(s) 107734, ISSN 0951-8320
Editor: Elsevier BV
DOI: 10.1016/j.ress.2021.107734

Effects of local coronary blood flow dynamics on the predictions of a model of in-stent restenosis

Autores: Pavel Zun, Andrey Svitenkov, Alfons Hoekstra
Publicado en: Journal of Biomechanics, Edición 120, 2021, Página(s) 110361, ISSN 0021-9290
Editor: Elsevier BV
DOI: 10.1016/j.jbiomech.2021.110361

An algorithm for finding and adding boundary conditions with the aim of solving the contact problem in computational mechanics

Autores: Velibor Isailovic, Nenad Filipovic
Publicado en: Simulation Modelling Practice and Theory, Edición 108, 2021, Página(s) 102247, ISSN 1569-190X
Editor: Elsevier BV
DOI: 10.1016/j.simpat.2020.102247

High Throughput Computation of Reference Ranges of Biventricular Cardiac Function on the UK Biobank Population Cohort

Autores: Rahman Attar, Marco Pereañez, Ali Gooya, Xènia Albà, Le Zhang, Stefan K. Piechnik, Stefan Neubauer, Steffen E. Petersen, Alejandro F. Frangi
Publicado en: Statistical Atlases and Computational Models of the Heart. Atrial Segmentation and LV Quantification Challenges - 9th International Workshop, STACOM 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Edición 11395, 2019, Página(s) 114-121, ISBN 978-3-030-12028-3
Editor: Springer International Publishing
DOI: 10.1007/978-3-030-12029-0_13

InSilc: 3D Reconstruction and plaque characterization tool

Autores: GEORGIA KARANASIOU; GEORGE RIGAS; SAVVAS KYRIAKIDIS; NIKOLAOS TACHOS; ANTONIS SAKELLARIOS; DIMITRIOS FOTIADIS
Publicado en: 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018
Editor: IEEE
DOI: 10.5281/zenodo.2017989

In Silico analysis of stent deployment - effect of stent design

Autores: Georgia S. Karanasiou; Nikolaos S. Tachos; Antonios Sakellarios; Claire Conway; Giancarlo Pennati; Lorenza Petrini; Lampros K. Michalis; Elazer R. Edelman; Dimitrios I. Fotiadis
Publicado en: 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018
Editor: IEEE
DOI: 10.5281/zenodo.2018351

Atherosclerotic Plaque Growth Prediction in Coronary Arteries using a Computational Multi-level Model: The Effect of Diabetes

Autores: Dimitris Pleouras; Antonis I. Sakellarios; Georgia S. Karanasiou; Savvas Kyriakidis; Panagiota Tsompou; Vassiliki I. Kigka; Dimitrios I. Fotiadis
Publicado en: IEEE BIBE 2019, Edición 2, 2019
Editor: IEEE
DOI: 10.5281/zenodo.3538010

A Novel Methodology for Detection of Lumen, Outer Wall, Plaques and Stent Struts in Coronary Arteries Using Optical Coherence Tomography

Autores: Savvas Kyriakidis, Antonis Sakellarios, Georgia Karanasiou, Dimitrios I. Fotiadis
Publicado en: 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE), 2019, Página(s) 697-701, ISBN 978-1-7281-4617-1
Editor: IEEE
DOI: 10.1109/bibe.2019.00131

InSilc: a cloud platform for in silico clinical trials for bioresorbable vascular scaffolds

Autores: Karanasiou, G.; Rigas, G.; Tachos, T.; Fotiadis, D.
Publicado en: 41st International Engineering in Medicine and Biology Conference (EMBC 2019), Edición 5, 2019
Editor: EMBC
DOI: 10.5281/zenodo.3537991

Resultado final

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