InSilc: In-silico trials for drug-eluting BVS design, development and evaluation

Risultati finali

Dissemination plan and activities v2

Report summarising the dissemination strategy and activities of the InSilc 2nd year

Project website, poster, flyer and social media

Report presenting the InSilc website, poster, flyer and social media accounts

Quality Assurance plan

Report on the Quality Assurance plan

Dissemination plan and activities v3

Report summarising the dissemination strategy and activities of the InSilc 3rd year

Project handbook

Report on the project handbook

Final press release

Report of the InSilc final press release

Dissemination plan and activities v1

Report summarising the dissemination strategy and activities of the InSilc 1st year

Pubblicazioni

A Novel Approach to Generate a Virtual Population of Human Coronary Arteries for In Silico Clinical Trials of Stent Design

Autori: Dimitrios Pleouras, Antonis Sakellarios, George Rigas, Georgia S. Karanasiou, Panagiota Tsompou, Gianna Karanasiou, Vassiliki Kigka, Savvas Kyriakidis, Vasileios Pezoulas, George Gois, Nikolaos Tachos, Aidonis Ramos, Gualtiero Pelosi, Silvia Rocchiccioli, Lampros Michalis, Dimitrios I. Fotiadis
Pubblicato in: IEEE Open Journal of Engineering in Medicine and Biology, Numero 2, 2021, Pagina/e 201-209, ISSN 2644-1276
Editore: IEEE
DOI: 10.1109/ojemb.2021.3082328

From the real device to the digital twin: A coupled experimental-numerical strategy to investigate a novel bioresorbable vascular scaffold

Autori: Luca Antonini, Francesca Berti, Benedetta Isella, Dipok Hossain, Lorenzo Mandelli, Giancarlo Pennati, Lorenza Petrini
Pubblicato in: PLOS ONE, Numero 16/6, 2021, Pagina/e e0252788, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0252788

Modulated molecular markers of restenosis and thrombosis by in-vitro vascular cells exposed to bioresorbable scaffolds

Autori: F Vozzi, A Cecchettini, M Cabiati, Fornaro Mg, P Aretini, S Del Ry, S Rocchiccioli, G Pelosi
Pubblicato in: Biomedical Materials, Numero 16/4, 2021, Pagina/e 045039, ISSN 1748-6041
Editore: Institute of Physics Publishing
DOI: 10.1088/1748-605x/ac0401

Non-Invasive Prediction of Site-Specific Coronary Atherosclerotic Plaque Progression using Lipidomics, Blood Flow, and LDL Transport Modeling

Autori: Antonis I. Sakellarios, Panagiota Tsompou, Vassiliki Kigka, Panagiotis Siogkas, Savvas Kyriakidis, Nikolaos Tachos, Georgia Karanasiou, Arthur Scholte, Alberto Clemente, Danilo Neglia, Oberdan Parodi, Juhani Knuuti, Lampros K. Michalis, Gualtiero Pelosi, Silvia Rocchiccioli, Dimitrios I. Fotiadis
Pubblicato in: Applied Sciences, Numero 11/5, 2021, Pagina/e 1976, ISSN 2076-3417
Editore: MDPI
DOI: 10.3390/app11051976

Physical and mechanical degradation behaviour of semi-crystalline PLLA for bioresorbable stent applications

Autori: Katarzyna Polak-Kraśna, Ali Reza Abaei, Reyhaneh Neghabat Shirazi, Eoin Parle, Oliver Carroll, William Ronan, Ted J. Vaughan
Pubblicato in: Journal of the Mechanical Behavior of Biomedical Materials, Numero 118, 2021, Pagina/e 104409, ISSN 1751-6161
Editore: Elsevier BV
DOI: 10.1016/j.jmbbm.2021.104409

Validation of the computational model of a coronary DES delivery system: a fundamental step towards in-silico clinical trials

Autori: Antonini, Luca; Mandelli, Lorenzo; Berti, Francesca; Pennati, Giancarlo; Petrini, Lorenza
Pubblicato in: Journal of the Mechanical Behavior of Biomedical Materials, 2021, ISSN 1751-6161
Editore: Elsevier BV

In vitro and in silico testing of partially and fully bioresorbable vascular scaffold

Autori: Nenad Filipovic, Dalibor Nikolic, Velibor Isailovic, Miljan Milosevic, Vladimir Geroski, Georgia Karanasiou, Martin Fawdry, Aiden Flanagan, Dimitrios Fotiadis, Milos Kojic
Pubblicato in: Journal of Biomechanics, Numero 115, 2021, Pagina/e 110158, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.1016/j.jbiomech.2020.110158

Multimodal Loading Environment Predicts Bioresorbable Vascular Scaffolds’ Durability

Autori: Pei-Jiang Wang, Francesca Berti, Luca Antonini, Farhad Rikhtegar Nezami, Lorenza Petrini, Francesco Migliavacca, Elazer R. Edelman
Pubblicato in: Annals of Biomedical Engineering, Numero 49/5, 2021, Pagina/e 1298-1307, ISSN 0090-6964
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10439-020-02673-z

Population‐specific modelling of between/within‐subject flow variability in the carotid arteries of the elderly

Autori: Toni Lassila, Ali Sarrami‐Foroushani, SeyedMostafa Hejazi, Alejandro F. Frangi
Pubblicato in: International Journal for Numerical Methods in Biomedical Engineering, Numero 36/1, 2020, ISSN 2040-7939
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cnm.3271

Is modeling stents still an important issue?

Autori: Francesco Migliavacca
Pubblicato in: Procedia Structural Integrity, Numero 15, 2019, Pagina/e 46-50, ISSN 2452-3216
Editore: ELSEVIER
DOI: 10.1016/j.prostr.2019.07.009

A computational model for prediction of clot platelet content in flow-diverted intracranial aneurysms

Autori: Sarrami-Foroushani, Ali; Lassila, Toni; Hejazi, Seyed Mostafa; Nagaraja, Sanjoy; Bacon, Andrew; Frangi, Alejandro F.
Pubblicato in: Journal of Biomechanics, 2019, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.5281/zenodo.2671637

Three-dimensional reconstruction and NURBS-based structured meshing of coronary arteries from the conventional X-ray angiography projection images

Autori: Arso M. Vukicevic, Serkan Çimen, Nikola Jagic, Gordana Jovicic, Alejandro F. Frangi, Nenad Filipovic
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-19440-9

Impact of bioresorbable scaffold design characteristics on local haemodynamic forces: an ex vivo assessment with computational fluid dynamics simulations

Autori: Imane Tarrahi, Monika Colombo, Eline M.J. Hartman, Maria Natalia Tovar Forero, Ryo Torii, Claudio Chiastra, Joost Daemen, Frank J.H. Gijsen
Pubblicato in: EuroIntervention, Numero 16/11, 2020, Pagina/e e930-e937, ISSN 1969-6213
Editore: EuroIntervention
DOI: 10.4244/eij-d-19-00657

Non-intrusive and semi-intrusive uncertainty quantification of a multiscale in-stent restenosis model

Autori: Dongwei Ye, Anna Nikishova, Lourens Veen, Pavel Zun, Alfons G. Hoekstra
Pubblicato in: Reliability Engineering & System Safety, Numero 214, 2021, Pagina/e 107734, ISSN 0951-8320
Editore: Elsevier BV
DOI: 10.1016/j.ress.2021.107734

Effects of local coronary blood flow dynamics on the predictions of a model of in-stent restenosis

Autori: Pavel Zun, Andrey Svitenkov, Alfons Hoekstra
Pubblicato in: Journal of Biomechanics, Numero 120, 2021, Pagina/e 110361, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.1016/j.jbiomech.2021.110361

An algorithm for finding and adding boundary conditions with the aim of solving the contact problem in computational mechanics

Autori: Velibor Isailovic, Nenad Filipovic
Pubblicato in: Simulation Modelling Practice and Theory, Numero 108, 2021, Pagina/e 102247, ISSN 1569-190X
Editore: Elsevier BV
DOI: 10.1016/j.simpat.2020.102247

High Throughput Computation of Reference Ranges of Biventricular Cardiac Function on the UK Biobank Population Cohort

Autori: Rahman Attar, Marco Pereañez, Ali Gooya, Xènia Albà, Le Zhang, Stefan K. Piechnik, Stefan Neubauer, Steffen E. Petersen, Alejandro F. Frangi
Pubblicato in: Statistical Atlases and Computational Models of the Heart. Atrial Segmentation and LV Quantification Challenges - 9th International Workshop, STACOM 2018, Held in Conjunction with MICCAI 2018, Granada, Spain, September 16, 2018, Revised Selected Papers, Numero 11395, 2019, Pagina/e 114-121, ISBN 978-3-030-12028-3
Editore: Springer International Publishing
DOI: 10.1007/978-3-030-12029-0_13

InSilc: 3D Reconstruction and plaque characterization tool

Autori: GEORGIA KARANASIOU; GEORGE RIGAS; SAVVAS KYRIAKIDIS; NIKOLAOS TACHOS; ANTONIS SAKELLARIOS; DIMITRIOS FOTIADIS
Pubblicato in: 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018
Editore: IEEE
DOI: 10.5281/zenodo.2017989

In Silico analysis of stent deployment - effect of stent design

Autori: Georgia S. Karanasiou; Nikolaos S. Tachos; Antonios Sakellarios; Claire Conway; Giancarlo Pennati; Lorenza Petrini; Lampros K. Michalis; Elazer R. Edelman; Dimitrios I. Fotiadis
Pubblicato in: 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018
Editore: IEEE
DOI: 10.5281/zenodo.2018351

Atherosclerotic Plaque Growth Prediction in Coronary Arteries using a Computational Multi-level Model: The Effect of Diabetes

Autori: Dimitris Pleouras; Antonis I. Sakellarios; Georgia S. Karanasiou; Savvas Kyriakidis; Panagiota Tsompou; Vassiliki I. Kigka; Dimitrios I. Fotiadis
Pubblicato in: IEEE BIBE 2019, Numero 2, 2019
Editore: IEEE
DOI: 10.5281/zenodo.3538010

A Novel Methodology for Detection of Lumen, Outer Wall, Plaques and Stent Struts in Coronary Arteries Using Optical Coherence Tomography

Autori: Savvas Kyriakidis, Antonis Sakellarios, Georgia Karanasiou, Dimitrios I. Fotiadis
Pubblicato in: 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE), 2019, Pagina/e 697-701, ISBN 978-1-7281-4617-1
Editore: IEEE
DOI: 10.1109/bibe.2019.00131

InSilc: a cloud platform for in silico clinical trials for bioresorbable vascular scaffolds

Autori: Karanasiou, G.; Rigas, G.; Tachos, T.; Fotiadis, D.
Pubblicato in: 41st International Engineering in Medicine and Biology Conference (EMBC 2019), Numero 5, 2019
Editore: EMBC
DOI: 10.5281/zenodo.3537991

Risultati finali

Pubblicazioni

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