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Prostate Cancer DIagnOsis and TreatmeNt Enhancement through the Power of Big Data in EuRope

Obiettivo

Prostate Cancer (PCa) is the second leading cause of cancer, among men in Europe. There are currently major unmet needs in this field, such as insufficient knowledge on risk factors that contribute to PCa and on patient characteristics (including genetic profiles) that could facilitate patient stratification. Finally, there is lack of meaningful engagement of all key stakeholders, while the knowledge currently gained from clinical practice and real life data is not being fed back into PCa patients’ care pathways. There is thus a need for better definition of PCa across all stages, improved patient’s stratification at diagnosis, and standardisation of PCa-related outcomes based on real life data.

PIONEER’s unique dual approach is to first identify critical evidence gaps in PCa by respected Key Opinion Leaders, and then embark on a research priority setting exercise that reflects the needs of all key stakeholders in PCa management. To achieve this, PIONEER has brought together comprehensive datasets that consists of the most relevant prostate clinical trials and registries, large epidemiological cohorts, electronic heath records, and real-life data from different European (and non-European) patient populations. These unique data sets will be integrated, standardised, harmonised and analysed using approaches that are built on our experience of similar previous IMI projects i.e EMIF, and eTRIKS, and analysed using a unique set of methodologies and advanced analytics methods (OMOP, eHS). PIONEER has already performed a first PCa research priority setting survey, where major stakeholders were asked to identify the current unmet needs in PCa. The five most important open questions will be used as pilot studies to verify PIONEER’s research framework. As such, PIONEER’s deliverables will be outcome-driven, value-based and patient-centric, and relevant to all key stakeholders, as they would have been meaningfully involved from the inception of the project.

Campo scientifico

Parole chiave

Programma(i)

Argomento(i)

Invito a presentare proposte

H2020-JTI-IMI2-2016-10-two-stage

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Meccanismo di finanziamento

RIA - Research and Innovation action

Coordinatore

STICHTING EUROPEAN UROLOGICAL FOUNDATION
Contribution nette de l'UE
€ 797 439,28
Indirizzo
Mr. E.N. van Kleffenstraat 5
6842 CV Arnhem
Paesi Bassi

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PMI

L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione.
Sì
Regione
Oost-Nederland Gelderland Arnhem/Nijmegen
Tipo di attività
Other
Collegamenti
Costo totale
€ 1 842 439,28

Partecipanti (37)

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Ultimo aggiornamento: 20 Maggio 2024

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Permalink: https://cordis.europa.eu/project/id/777492/it

European Union, 2024