Prostate Cancer DIagnOsis and TreatmeNt Enhancement through the Power of Big Data in EuRope

Projektinformationen

PIONEER

ID Finanzhilfevereinbarung: 777492

DOI

10.3030/777492

Projekt abgeschlossen

EK-Unterschriftsdatum 14 Juni 2018

Startdatum 1 Mai 2018

Enddatum 31 Oktober 2023

Finanziert unter

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Gesamtkosten

€ 13 549 159,89

EU-Beitrag

€ 6 000 000,00

Koordiniert durch

STICHTING EUROPEAN UROLOGICAL FOUNDATION
Netherlands

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Documents, reports (6)

Overview of the economics of PCa, including determinants of future resource use
Characterization and mapping of regulator and payer evidence challenges in PCa

Report on the key evidence challengesgaps for regulators and payerHTA authorities in the last 23 years including an analyses of the key decision drivers of key payerHTA for access decisions and assessment of current inequalities in patient access to prostate cancer treatments across Europe

Online website to translate use of standard outcomes and DPFs into medical practice
White Paper presenting PIONEER policy strategy

White Paper to inform regulators at EU, national and regional level of the PIONEER prostate cancer policy strategy clearly outlining how the PIONEER recommendations and research outputs can be translated into policy to support regulator/HTA authority decision making.

Policy papers 1/3
Prostate cancer reference models

A publicly available health economic simulation model with technical documentation.

Other (1)

Central open access catalogue deployed and customized according to consortium requirements.

Veröffentlichungen

Peer reviewed articles (11)

Diagnostic and prognostic factors in patients with prostate cancer: a systematic review protocol

Autoren: Katharina Beyer, Lisa Moris, Michael Lardas, Anna Haire, Francesco Barletta, Simone Scuderi, Eleni Vradi, Giorgio Gandaglia, Muhammad Imran Omar, Steven MacLennan, Jihong Zong, Bahman Farahmand, Sara J Maclennan, Zsuzsanna Devecseri, Alex Asiimwe, Laurence Collette, Anders Bjartell, James Ndow, Alberto Briganti, Mieke Van Hemelrijck
Veröffentlicht in: BMJ Open, Ausgabe 11/2, 2021, Seite(n) e040531, ISSN 2044-6055
Herausgeber: BMJ Publishing Group
DOI: 10.1136/bmjopen-2020-040531

A Systematic Review to Evaluate Patient-Reported Outcome Measures (PROMs) for Metastatic Prostate Cancer According to the COnsensus-Based Standard for the Selection of Health Measurement INstruments (COSMIN) Methodology

Autoren: Ratti, Maria Monica ; Gandaglia, Giorgio; Sisca, Elena Silvia ; Derevianko, Alexandra; Alleva, Eugenia; Beyer, Katharina; Moss, Charlotte; Barletta, Francesco; Scuderic, Simone; Omar, Muhammad Imran; Maclennan, Steven; Williamson, Paula R.; Zong, Jihong; MacLennan, Sara J.; Mottet, Nicolas; Cornford, Philip; Aiyegbusi, Olalekan Lee; Van Hemelrijck, Mieke; N’Dow, James; Briganti, Alberto
Veröffentlicht in: Cancers, Ausgabe 14(20), 2022, Seite(n) 5120, ISSN 2072-6694
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14205120

The Key Role of Patient Involvement in the Development of Core Outcome Sets in Prostate Cancer

Autoren: Katharina Beyer, Sara J. MacLennan, Lisa Moris, Michael Lardas, Ken Mastris, Gary Hooker, Robert Greene, Erik Briers, Muhammad Imran Omar, Jemma Healey, Sheela Tripathee, Giorgio Gandaglia, Lionne D.F. Venderbos, Emma J.Smith, Josefine Bjorkqvist, Alex Asiimwe, Johanne Huber, Monique J. Roobol, Jihong Zong, Anders Bjartell, James N’Dow, Alberto Briganti, Steven MacLennan, Mieke Van Hemelrijck, o
Veröffentlicht in: European Urology Focus, Ausgabe 7/5, 2021, Seite(n) 943-946, ISSN 2405-4569
Herausgeber: Elsevier B.V.
DOI: 10.1016/j.euf.2021.09.008

Clinical Characterization of Patients Diagnosed with Prostate Cancer and Undergoing Conservative Management: A PIONEER Analysis Based on Big Data

Autoren: Giorgio Gandaglia, Francesco Pellegrino, Asieh Golozar, Bertrand De Meulder, Thomas Abbott, Ariel Achtman, Muhammad Imran Omar, Thamir Alshammari, Carlos Areia,Alex Asiimwe, Katharina Beyer, Anders Bjartell, Riccardo Campi, Philip Cornford,Thomas Falconer, Qi Feng, Mengchun Gong, Ronald Herrera, Nigel Hughes, Tim Hulsen, Adam Kinnaird, Lana Y.H. Lai, Gianluca Maresca, Nicolas Mottet, Marek Oja, Pe
Veröffentlicht in: European Urology, 2023, ISSN 0302-2838
Herausgeber: Elsevier BV
DOI: 10.1016/j.eururo.2023.06.012

Standardising the Assessment of Patient-reported Outcome Measures in Localised Prostate Cancer. A Systematic Review

Autoren: Maria Monica Ratti, Giorgio Gandaglia, Eugenia Alleva, Luca Leardini, Elena Silvia Sisca, Alexandra Derevianko, Federica Furnari, Serena Mazzoleni Ferracini, Katharina Beyer, Charlotte Moss, Francesco Pellegrino, Gabriele Sorce, Francesco Barletta, Simone Scuderi, Muhammad Imran Omar, Steven MacLennan, Paula R.Williamson, Jihong Zong, Sara J.MacLennan, Nicolas Mottet, Philip Cornford, Olalekan Lee
Veröffentlicht in: European Urology Oncology, Ausgabe 5/2, 2022, Seite(n) 153-163, ISSN 2588-9311
Herausgeber: Elsevier B.V.
DOI: 10.1016/j.euo.2021.10.004

Updating and Integrating Core Outcome Sets for Localised, Locally Advanced, Metastatic, and Nonmetastatic Castration-resistant Prostate Cancer: An Update from the PIONEER Consortium

Autoren: Katharina Beyer, Lisa Moris, Michael Lardas, Muhammad Imran Omar, Jemma Healey, Sheela Tripathee, Giorgio Gandaglia, Lionne D.F. Venderbos, Eleni Vradi. Thomas van den Broeck, Peter-Paul Willems, Tiago Antunes-Lopes, Luis Pacheco Figueiredo, Serenella Monaga, Francesco Esperto, Stephen Flaherty, Zsuzsanna Devecseri, Thomas B.L. Lam, Paula R.Williamson, Rakesh Heer, Emma J.Smith, Alex Asiimwe, Joha
Veröffentlicht in: European Urology, Ausgabe 81/5, 2022, Seite(n) 503-514, ISSN 1569-9056
Herausgeber: Elsevier BV
DOI: 10.1016/j.eururo.2022.01.042

Introducing PIONEER: a project to harness big data in prostate cancer research

Autoren: Muhammad Imran Omar, Monique J. Roobol, Maria J. Ribal, Thomas Abbott, Paul-Michael Agapow, Sonia Araujo, Alex Asiimwe, Charles Auffray, Irina Balaur, Katharina Beyer, Chiara Bernini, Anders Bjartell, Alberto Briganti, John-Edward Butler-Ransohoff, Riccardo Campi, Marinel Cavelaars, Bertrand De Meulder, Zsuzsanna Devecseri, Marc Dietrich Voss, Konstantinos Dimitropoulos, Susan Evans-Axelsson, Bill
Veröffentlicht in: Nature Reviews Urology, Ausgabe 17/6, 2020, Seite(n) 351-361, ISSN 1759-4812
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41585-020-0324-x

Towards a European health research and innovation cloud (HRIC)

Autoren: F. M. Aarestrup, A. Albeyatti, W. J. Armitage, C. Auffray, L. Augello, R. Balling, N. Benhabiles, G. Bertolini, J. G. Bjaalie, M. Black, N. Blomberg, P. Bogaert, M. Bubak, B. Claerhout, L. Clarke, B. De Meulder, G. D’Errico, A. Di Meglio, N. Forgo, C. Gans-Combe, A. E. Gray, I. Gut, A. Gyllenberg, G. Hemmrich-Stanisak, L. Hjorth, Y. Ioannidis, S. Jarmalaite, A. Kel, F. Kherif, J. O. Korbel, C. L
Veröffentlicht in: Genome Medicine, Ausgabe 12/1, 2020, ISSN 1756-994X
Herausgeber: BioMed Central
DOI: 10.1186/s13073-020-0713-z

Unanswered questions in prostate cancer — findings of an international multi-stakeholder consensus by the PIONEER consortium

Autoren: Muhammad Imran Omar, Steven MacLennan, Maria J. Ribal, Monique J. Roobol, Konstantinos Dimitropoulos, Thomas van den Broeck, Sara J. MacLennan, Susan Evans Axelsson, Giorgio Gandaglia, Peter-Paul Willemse, Ken Mastris, John Butler Ransohoff, Zsuzsanna Devecseri , Thomas Abbott, Bertrand De Meulder, Anders Bjartell, Alex Asiimwe, James N’Dow & The PIONEER Consortium
Veröffentlicht in: Nature Reviews Urology, Ausgabe 20, 2023, Seite(n) 494-501, ISSN 1759-4812
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41585-023-00748-9

Secondary Treatment for Men with Localized Prostate Cancer: A Pooled Analysis of PRIAS and ERSPC-Rotterdam Data within the PIONEER Data Platform

Autoren: Katharina Beyer, Vera Straten, Sebastiaan Remmers, Steven MacLennan, Sara MacLennan, Giorgio Gandaglia, Peter-Paul M. Willemse, Ronald Herrera, Muhammad Imran Omar, Beth Russell, Johannes Huber, Markus Kreuz, Alex Asiimwe, Tom Abbott, Alberto Briganti, Mieke Van Hemelrijck, Monique J. Roobol, the PRIAS Consortium, the ERSPC Rotterdam Study Group and the PIONEER Consortium
Veröffentlicht in: Journal of Personalized Medicine, Ausgabe 12(5), 2022, Seite(n) 751, ISSN 2075-4426
Herausgeber: MDPI
DOI: 10.3390/jpm12050751

How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis

Autoren: Aino Siltari, Ragnar Lönnerbro, Karl Pang, Kirill Shiranov, Alex Asiimwe, Susan Evans-Axelsson, Billy Franks, Amit Kiran, Teemu J Murtola, Jack Schalken, Carl Steinbeisser, Anders Bjartell, Anssi Auvinen; PIONEER Consortium
Veröffentlicht in: Clinical Genitourinary Cancer, Ausgabe 21(2), 2022, Seite(n) 316, ISSN 1938-0682
Herausgeber: Elsevier
DOI: 10.1016/j.clgc.2022.09.006

Non-peer reviewed articles (1)

Prostate Cancer DIagnOsis and TreatmeNt Enhancement through the Power of Big Data in EuRope

Autoren: James N'Dow
Veröffentlicht in: Health Europa Quarterly, Ausgabe 20492405, 2019, ISSN 2049-2405
Herausgeber: Pan European Networks Ltd

Other (2)

Research Protocol for an Observational Health Data Analysis to Assess the Long-term Outcomes of Prostate Cancer Patients Undergoing Non-Interventional Management (i.e., Watchful Waiting) and the Impact of Comorbidities and Life Expectancy – PIONEER IMI’s “Big Data for Better Outcomes” program

Autoren: Giorgio Gandaglia Kees van Bochove Anders Bjartell Alberto Briganti Phil Conford Susan Evans Axelsson Asieh Golozar Mieke Van Hemelrijck Katharina Beyer Peter-Paul Willemse Muhammad Imran Omar James N’Dow Alex Asiimwe Monique Roobol Robert Snijder Carl Steinbeisser Roderick Van Den Bergh Samuel Fatoba Ariel Achtman Thamir M Alshammari Nicolas Thurin Adam Kinnaird Sebastian Remmers Emma Jane Smit
Veröffentlicht in: 2021
Herausgeber: Springer Nature
DOI: 10.21203/rs.3.pex-1468/v1

Development and validation of patient-level prediction models for symptoms, hospitalization and treatment initiation amongst prostate cancer patients on watchful waiting

Autoren: Sebastiaan Remmers Lana Lai Yin Hui Carolin Schimmelpfennig Peter-Paul Willemsen Markus Kreuz Philip Cornford Nicolas Mottet Nazanin Zounemat-Kermani
Veröffentlicht in: 2021
Herausgeber: Springer Nature
DOI: 10.21203/rs.3.pex-1525/v1