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Improved Methods and Actionable Tools for Enhancing Health Technology Assessment

Leistungen

Concrete dissemination and communication plan

This report will provide a detailed plan for all the activities that will be undertaken by partners to communicate and disseminate the results of the research. It will determine the target groups for different results and the most adequate communication and dissemination modes: publications, face-to-face and electronic dissemination.

An analytical framework outlining the determinants of HTA recommendations across settings based on primary data collection and primary analysis of secondary data

An analytical framework will be developed outlining the determinants of HTA recommendations across countries based on primary and secondary data with the aim to provide insights on the relevant value concerns of decision makers beyond costs and clinical effects.

State of art analysis in Europe with regard to chosen case studies

in this deliverable, a systematic retrieval and comparison will be carried out gathering HTA methodological and policy guidelines issued at regional and national levels across Europe, on HTA, budget impact evaluation, and patients’ public involvement (PPI). The comparison will hold on relevant aspects w.r.t. the aims of WP10 (those aspects to be impacted by considering adoption and implementation of candidate cost-effective technologies outside incremental innovations).

Revising the methodological aspects applied to the identification, measurement and valuation of social costs in economic evaluations.

This deliverable will provide a comprehensive view of the methodological advances in identification, measurement and valuation of labour losses and informal care time and the inclusion of this type of resources in methodological guidelines and economic evaluations of health care interventions across countries

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Veröffentlichungen

Real-world evidence to support Payer/HTA decisions about highly innovative technologies in the EU—actions for stakeholders

Autoren: Karen M. Facey, Piia Rannanheimo, Laura Batchelor, Marine Borchardt, Jo de Cock
Veröffentlicht in: International Journal of Technology Assessment in Health Care, Issue 36/4, 2020, Page(s) 459-468, ISSN 0266-4623
DOI: 10.1017/s026646232000063x

Cost transferability problems in economic evaluation as a framework for an European health care and social costs database

Autoren: Leticia García-Mochón, Joan Rovira Forns, Jaime Espin
Veröffentlicht in: Cost Effectiveness and Resource Allocation, Issue 19/1, 2021, ISSN 1478-7547
DOI: 10.1186/s12962-021-00294-4

The estimation of health state utility values in rare diseases: overview of existing techniques

Autoren: Michela Meregaglia, Elena Nicod, Michael Drummond
Veröffentlicht in: International Journal of Technology Assessment in Health Care, Issue 36/5, 2020, Page(s) 469-473, ISSN 0266-4623
DOI: 10.1017/s0266462320000665

‘Mapping’ Health State Utility Values from Non-preference-Based Measures: A Systematic Literature Review in Rare Diseases

Autoren: Michela Meregaglia, Amanda Whittal, Elena Nicod, Michael Drummond
Veröffentlicht in: PharmacoEconomics, Issue 38/6, 2020, Page(s) 557-574, ISSN 1170-7690
DOI: 10.1007/s40273-020-00897-4

How relevant are social costs in economic evaluations? The case of Alzheimer’s disease

Autoren: L. M. Peña-Longobardo, B. Rodríguez-Sánchez, J. Oliva-Moreno, I. Aranda-Reneo, J. López-Bastida
Veröffentlicht in: The European Journal of Health Economics, Issue 20/8, 2019, Page(s) 1207-1236, ISSN 1618-7598
DOI: 10.1007/s10198-019-01087-6

Can the Consideration of Societal Costs Change the Recommendation of Economic Evaluations in the Field of Rare Diseases? An Empirical Analysis

Autoren: Isaac Aranda-Reneo, Beatriz Rodríguez-Sánchez, Luz María Peña-Longobardo, Juan Oliva-Moreno, Julio López-Bastida
Veröffentlicht in: Value in Health, Issue 24/3, 2021, Page(s) 431-442, ISSN 1098-3015
DOI: 10.1016/j.jval.2020.10.014

Hospital contextual factors affecting the implementation of health technologies: a systematic review

Autoren: Adriano Grossi, Ilda Hoxhaj, Irene Gabutti, Maria Lucia Specchia, Americo Cicchetti, Stefania Boccia, Chiara de Waure
Veröffentlicht in: BMC Health Services Research, Issue 21/1, 2021, ISSN 1472-6963
DOI: 10.1186/s12913-021-06423-2

Assessing the Effect of Including Social Costs in Economic Evaluations of Diabetes-Related Interventions: A Systematic Review

Autoren: Beatriz Rodriguez-Sanchez, Isaac Aranda-Reneo, Juan Oliva-Moreno, Julio Lopez-Bastida
Veröffentlicht in: ClinicoEconomics and Outcomes Research, Issue Volume 13, 2021, Page(s) 307-334, ISSN 1178-6981
DOI: 10.2147/ceor.s301589

EQ-5D-Y Value Set for Slovenia

Autoren: Valentina Prevolnik Rupel, Marko Ogorevc
Veröffentlicht in: PharmacoEconomics, Issue 39/4, 2021, Page(s) 463-471, ISSN 1170-7690
DOI: 10.1007/s40273-020-00994-4

Considering the societal perspective in economic evaluations: a systematic review in the case of depression

Autoren: Juliane Andrea Duevel, Lena Hasemann, Luz María Peña-Longobardo, Beatriz Rodríguez-Sánchez, Isaac Aranda-Reneo, Juan Oliva-Moreno, Julio López-Bastida, Wolfgang Greiner
Veröffentlicht in: Health Economics Review, Issue 10/1, 2020, ISSN 2191-1991
DOI: 10.1186/s13561-020-00288-7

Are supplemental appraisal/reimbursement processes needed for rare disease treatments? An international comparison of country approaches

Autoren: Elena Nicod, Amanda Whittal, Michael Drummond, Karen Facey
Veröffentlicht in: Orphanet Journal of Rare Diseases, Issue 15/1, 2020, ISSN 1750-1172
DOI: 10.1186/s13023-020-01462-0

Examining the impact of different country processes for appraising rare disease treatments: a case study analysis

Autoren: Amanda Whittal, Elena Nicod, Mike Drummond, Karen Facey
Veröffentlicht in: International Journal of Technology Assessment in Health Care, Issue 37/1, 2021, ISSN 0266-4623
DOI: 10.1017/s0266462321000337

Using Discretely Integrated Condition Event Simulation To Construct Quantitative Benefit–Risk Models: The Example of Rotavirus Vaccination in France

Autoren: Hugo Arlegui, Gaëlle Nachbaur, Nicolas Praet, Bernard Bégaud, J. Jaime Caro
Veröffentlicht in: Clinical Therapeutics, Issue 42/10, 2020, Page(s) 1983-1991.e2, ISSN 0149-2918
DOI: 10.1016/j.clinthera.2020.08.013

Comparison of Adult and Adolescent Preferences Toward EQ-5D-Y-3L Health States

Autoren: Valentina Prevolnik Rupel, Juan M. Ramos-Goñi, Marko Ogorevc, Simone Kreimeier, Kristina Ludwig, Wolfgang Greiner
Veröffentlicht in: Value in Health, 2021, ISSN 1098-3015
DOI: 10.1016/j.jval.2021.03.019

PNS26 Appropriate Indices of Inflation to Update Prices and Unit Costs of Healthcare Goods and Services for Use in Economic Evaluation

Autoren: J. Espin, D. Epstein, A. Gaggero, J. Rovira
Veröffentlicht in: Value in Health, Issue 23, 2020, Page(s) S648, ISSN 1098-3015
DOI: 10.1016/j.jval.2020.08.1470

The Use of Patient-Reported Outcome Measures in Rare Diseases and Implications for Health Technology Assessment

Autoren: Amanda Whittal, Michela Meregaglia, Elena Nicod
Veröffentlicht in: The Patient - Patient-Centered Outcomes Research, 2021, ISSN 1178-1653
DOI: 10.1007/s40271-020-00493-w

EQ-5D-5L Slovenian population norms

Autoren: Valentina Prevolnik Rupel, Marko Ogorevc
Veröffentlicht in: Health and Quality of Life Outcomes, Issue 18/1, 2020, ISSN 1477-7525
DOI: 10.1186/s12955-020-01584-w

Assessing hospital performance indicators. What dimensions? Evidence from an umbrella review

Autoren: Elettra Carini, Irene Gabutti, Emanuela Maria Frisicale, Andrea Di Pilla, Angelo Maria Pezzullo, Chiara de Waure, Americo Cicchetti, Stefania Boccia, Maria Lucia Specchia
Veröffentlicht in: BMC Health Services Research, Issue 20/1, 2020, ISSN 1472-6963
DOI: 10.1186/s12913-020-05879-y

To What Extent Do Patient Preferences Differ From General Population Preferences?

Autoren: Kristina Ludwig, Juan M. Ramos-Goñi, Mark Oppe, Simone Kreimeier, Wolfgang Greiner
Veröffentlicht in: Value in Health, 2021, ISSN 1098-3015
DOI: 10.1016/j.jval.2021.02.012

Implementing Outcomes-Based Managed Entry Agreements for Rare Disease Treatments: Nusinersen and Tisagenlecleucel

Autoren: Karen M. Facey, Jaime Espin, Emma Kent, Angèl Link, Elena Nicod, Aisling O’Leary, Entela Xoxi, Inneke van de Vijver, Anna Zaremba, Tatyana Benisheva, Andrius Vagoras, Sheela Upadhyaya
Veröffentlicht in: PharmacoEconomics, 2021, ISSN 1170-7690
DOI: 10.1007/s40273-021-01050-5

Accounting for Unobservable Preference Heterogeneity and Evaluating Alternative Anchoring Approaches to Estimate Country-Specific EQ-5D-Y Value Sets: A Case Study Using Spanish Preference Data

Autoren: Ramos-Goñi JM, Oppe M, Estévez-Carrillo A, Rivero-Arias O, Wolfgang G, Kreimeier S, Ludwig K, Rupel V
Veröffentlicht in: Value in Health, 2021, ISSN 1098-3015
DOI: 10.1016/j.jval.2021.10.013

Multi-criteria decision analysis for health technology assessment: addressing methodological challenges to improve the state of the art

Autoren: Mónica D. Oliveira, Inês Mataloto, Panos Kanavos
Veröffentlicht in: The European Journal of Health Economics, 2019, Page(s) 1-28, ISSN 1618-7598
DOI: 10.1007/s10198-019-01052-3

Driving health technologies towards performance: a contextualisation within the hospital setting

Autoren: Gabutti I
Veröffentlicht in: International Journal of Technology, Policy and Management, 2020, ISSN 1468-4322
DOI: 10.21203/rs.3.rs-109606/v1

A general framework for classifying costing methods for economic evaluation of health care

Autoren: Zuzana Špacírová, David Epstein, Leticia García-Mochón, Joan Rovira, Antonio Olry de Labry Lima, Jaime Espín
Veröffentlicht in: The European Journal of Health Economics, Issue 21/4, 2020, Page(s) 529-542, ISSN 1618-7598
DOI: 10.1007/s10198-019-01157-9

PND35 Social Costs in Multiple Sclerosis Economic Evaluations: Do Their Inclusion Change the Results and Conclusions? a Systematic Review

Autoren: J. Lopez-Bastida, A. Cicchetti, B. Rodríguez-Sánchez, S. Daugbjerg, L.M. Peña-Longobardo, I. Aranda-Reneo, J. Oliva-Moreno
Veröffentlicht in: Value in Health, Issue 23, 2020, Page(s) S628-S629, ISSN 1098-3015
DOI: 10.1016/j.jval.2020.08.1360

PMH14 Considering the Societal Perspective in Economic Evaluations: A Systematic Review in the Case of Depression-Related Interventions

Autoren: J. Lopez-Bastida, J.A. Düvel, L. Hasemann, L.M. Peña-Longobardo, B. Rodríguez-Sánchez, I. Aranda-Reneo, J. Oliva-Moreno, W. Greiner
Veröffentlicht in: Value in Health, Issue 23, 2020, Page(s) S586, ISSN 1098-3015
DOI: 10.1016/j.jval.2020.08.1092

PDB35 Assessing the Effect of Including Social Costs in Economic Evaluations: A Systematic Review of Diabetes-Related Interventions

Autoren: J. Lopez-Bastida, B. Rodríguez-Sánchez, I. Aranda-Reneo, J. Oliva-Moreno
Veröffentlicht in: Value in Health, Issue 23, 2020, Page(s) S511-S512, ISSN 1098-3015
DOI: 10.1016/j.jval.2020.08.632

PRO19 THE ROLE PLAYED BY SOCIAL COSTS IN ECONOMIC EVALUATIONS OF RARE DISEASE INTERVENTIONS

Autoren: J. Lopez Bastida, I. Aranda-Reneo, L.M. Peña-Longobardo, B. Rodríguez-Sánchez, J. Oliva-Moreno
Veröffentlicht in: Value in Health, Issue 22, 2019, Page(s) S844, ISSN 1098-3015
DOI: 10.1016/j.jval.2019.09.2350

Collaborative value modelling in widely participated decision support processes

Autoren: Carlos A. Bana e Costa, Ana C.L. Vieira, Mónica D. Oliveira, João Bana e Costa
Veröffentlicht in: EMC-ICDSST 2019 Proceedings – online version Euro mini international conference on decision support system technology, 2019, Page(s) 136-140