CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.
Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .
Rezultaty
this will produce enduser friendly manuals for use and develop training packages to equip endusers with the requisite lowlevel skills to undertake DICE modelling The training package will be pursued as an online publicly accessible package
A review of methods used to extrapolate RCT outcomes using Real World Data and Guidance relating to the matching of data from RCTs and Observational or Registry data banks (odnośnik otworzy się w nowym oknie)This deliverable will review methods used to extrapolate health benefits and treatment costs and will provide guidance on the matching of data from RCTs and Observational or registry data banks It will also outline the manner in which such matched data can form the basis for estimation of longterm outcomes such as average life expectancy
Concrete dissemination and communication plan (odnośnik otworzy się w nowym oknie)This report will provide a detailed plan for all the activities that will be undertaken by partners to communicate and disseminate the results of the research. It will determine the target groups for different results and the most adequate communication and dissemination modes: publications, face-to-face and electronic dissemination.
Algorithm for the estimation of the fiscal impact of new technologies (odnośnik otworzy się w nowym oknie)Algorithm for the estimation of the fiscal impact of new technologies The algorithm will be developed based on the results of the literature review and partner feedback collected through a survey
A toolbox on candidate cost-effective technologies for HTA producers and users (odnośnik otworzy się w nowym oknie)This deliverable will provide a specific methodological and policy guidance concerning the evaluation and implementation of candidate costeffective technologies outside incremental innovations It will include indications about suitable strategies for patient and public involvement reflecting stakeholder preferences and guidance on the use of these technologies according to regulatory environments and ethical principles in HTA
An analytical framework outlining the determinants of HTA recommendations across settings based on primary data collection and primary analysis of secondary data (odnośnik otworzy się w nowym oknie)An analytical framework will be developed outlining the determinants of HTA recommendations across countries based on primary and secondary data with the aim to provide insights on the relevant value concerns of decision makers beyond costs and clinical effects
Toolkit of instruments to identify the clinical variability and its impact on the use of health technology (odnośnik otworzy się w nowym oknie)Development of a toolkit which will include among others a checklist and a projection model aimed at analysing the different factors ie behaviour of healthcare professionals and organizational issues further to the technical characteristic of technology that contribute to clinical variability The toolkit will thus support local decisionmakers in identifying those actions which are most likely to enable an effective and appropriate use of health technologies
Guidelines for cost definitions and harmonization of cost accounting methodologies and methodology that determines the common basket (odnośnik otworzy się w nowym oknie)This deliverable provides a set of recommended definitions principles criteria and procedures for calculating health care costs for economic evaluation in the EU
Comparison of EQ-5D-5L value sets from different disease areas in 2 countries (Germany and Spain) (odnośnik otworzy się w nowym oknie)This report will provide a detailed document describing the differences between patients preference and general population preference regarding the health states described by the EQ5D5L instrument
Stakeholders’ perspective: a political economy approach: (odnośnik otworzy się w nowym oknie)This deliverable will analyse the obstacles and potential drivers in these areas using behavioural economics as well as ethical and legal analyses
Recommendations on how to analyse and interpret non-randomised studies (odnośnik otworzy się w nowym oknie)This document will recommend options for the analysis of nonrandomised studies and for each option how to assess the residual risk of bias The recommendations will be based on an empirical comparison of the performance of different analytical methods and will include pragmatic considerations relevant to HTA agencies such as an assessment of the data requirements for and the time taken to run the analytical methods
Value sets for the EQ-5D-Y in Germany, Slovenia and Spain and Comparison of EQ-5D-Y value sets across countries (odnośnik otworzy się w nowym oknie)This report will provide the countryspecific algorithms to calculate index values scores for the EQ5DY instrument in Germany Slovenia and Spain This includes regression coefficients and software In addition it will provide a detailed document describing the differences between adolescents preference for their own and general population preference for adolescent
Database (final version) with the initial core dataset of costs and the User Manual; Final version of the Guidelines; List of standard unit costs with country values. (odnośnik otworzy się w nowym oknie)This deliverable will produce an open database of unit health costs that will be linked to project website along with a manual for user instructions A first website version of the database will be presented in the M35 of the project An arrangement will be made with a HTA institution in order to ensure that the database is updated and maintained when this project comes to an end
case studies to quantify important different ways of incorporating the social perspective into economic analysis to inform European decisions. (odnośnik otworzy się w nowym oknie)By using a number of case studies this deliverable will quantify different ways of incorporating the social perspective into economic analysis It will focus on differences in methodological aspects such as costs included methods used to estimate costs resources used discount rate applied among others The analysis will be carried out across different European countries and will select a number of up to 5 interventions medicines and devices in therapeutic areas of interest
Validation of the DICE modelling technique against existing methods and Speeding up execution of the DICE Simulation macro (odnośnik otworzy się w nowym oknie)Validation of the DICE modelling technique against existing methods and Speeding up execution of the DICE Simulation macro This deliverable is two parts 1 a report on the Internal Validation of the DICE Simulation model against industry standard models It will consist of rebuilding existing models of standard type using DICE simulation and comparing ICER results Comparison will also focus on technical aspects including ease of model construction file size run time and ease of modification 2 an enhanced ready to use DICE Simulation Model It will be based around a number of technical fixes of the existing Beta prototype such as avoidance of repeated reading from and writing to worksheet the carrying out calculations in memory improving the placeholding of results in memory until simulation is complete incorporating faster calculation algorithms as well as creation of standard templates for commonly encountered modelling problems
State of art analysis in Europe with regard to chosen case studies (odnośnik otworzy się w nowym oknie)in this deliverable, a systematic retrieval and comparison will be carried out gathering HTA methodological and policy guidelines issued at regional and national levels across Europe, on HTA, budget impact evaluation, and patients’ public involvement (PPI). The comparison will hold on relevant aspects w.r.t. the aims of WP10 (those aspects to be impacted by considering adoption and implementation of candidate cost-effective technologies outside incremental innovations).
Results from designing, implementing and validating large scale Delphi processes and describing multi-criteria value models within a common value framework to evaluate new medicines (odnośnik otworzy się w nowym oknie)Following a combination of participatory processes with the engagement of key stakeholders Delphi panels and workshops a flexible methodological framework will be designed for enabling the structuring of multicriteria evaluation models for new medicines in HTA that can accommodate the views and preferences of a wide range of decisionmakers across health care systems
Toolkit including a list of relevant indicators to capture hospital performance variability and Toolkit to assess the transferability of evidence produced in other jurisdictions and decision-making levels (odnośnik otworzy się w nowym oknie)Evidence based indicators will be developed to measure the hospitals performance in terms of efficiency and health outcomes the schedule of assessment and the threshold value will also be defined A set of items describing the hospitals organization in terms of legal status size degree of specialization uptake of innovation and methods used for decision making upon health technologies will be identified The relation between the mentioned elements will be explored As a second section of the deliverable a focus on the assessment of health technologies will be done constructing a standard methodology to assess the transferability of evidence used to inform decision making
Results from applying the value framework to case studies in HTA agencies and Insights for resource allocation and policy-making (odnośnik otworzy się w nowym oknie)In collaboration with HTA agencies and through a combination of participatory processes with the engagement of relevant stakeholders Delphi panels and decision conferences the methodological framework will be tested in practice through the form of case studies as part of which contextspecific evaluation models will be structured for the assessment of alternative sets of medicines for particular disease indications Recommendations will be produced on the application of the new methods as tools for resource allocation in health care and more precisely on how they can inform decisionmaking around coverage and pricing of new medicines
Paper describing the meta-epidemiological comparison of effect sizes in the matched studies (odnośnik otworzy się w nowym oknie)This paper will report how we identified matched pairs of randomised and nonrandomised studies of the same intervention in comparable populations and our analysis of whether and to what extent the treatment effects obtained from the former study design differ from the latter
Evidence from pilot application from selected therapeutic areas (odnośnik otworzy się w nowym oknie)Evidence from pilot application from selected therapeutic areas These applications will be utilized to test the model and the algorithm produced
Revising the methodological aspects applied to the identification, measurement and valuation of social costs in economic evaluations. (odnośnik otworzy się w nowym oknie)This deliverable will provide a comprehensive view of the methodological advances in identification measurement and valuation of labour losses and informal care time and the inclusion of this type of resources in methodological guidelines and economic evaluations of health care interventions across countries
Core dataset of social costs (odnośnik otworzy się w nowym oknie)Core dataset of social costs and link this to the dataset proposed in WP2 which will contain all cost items with a manual on how to use them The database will be designed and developed in a way that allows its future updating and continuity after the end of the present project
A horizontal and vertical expose of lessons learned and policy recommendations (odnośnik otworzy się w nowym oknie)This deliverables will bring together the findings and novelties produced in each WP providing a concrete synthesis and analysis of the policy implications of the research results for HTA in the domains researched upon It will identify how the research results can be incorporated in the decisionmaking process and implemented at national supranational and international level and what implications are there for specific stakeholders
Publikacje
Autorzy:
Facey, K; Xoxi, E; Kent, E; Junghans, T; Whittal, A; Drummond, M; Nicod, E; Upadhyaya, S
Opublikowane w:
Numer 4, 2021
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5032658
Autorzy:
Spacirova, Zuzana; Mochón, Leticia García; Rovira, Joan; Espín, Jaime
Opublikowane w:
Numer 4, 2021
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5044967
Autorzy:
Whittal, Amanda; Nicod, Elena; Facey, Karen; Drummond, Michael
Opublikowane w:
Numer 2, 2020
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5019195
Autorzy:
Spacirova, Zuzana; Mochón, Leticia García; Rovira, Joan; Epstein, David; Espín, Jaime
Opublikowane w:
Numer 6, 2021
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5044847
Autorzy:
Facey, K; Whittal, A; Drummond, M; Upadhyaya, S; Junghans, T; Nicod, E
Opublikowane w:
Numer 1, 2021
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5032615
Autorzy:
Oliva-Moreno, Juan; Rodríguez-Sánchez, Beatriz; Peña-Longobardo, Luz María; Aranda-Reneo, Isaac; López-Bastida, Julio
Opublikowane w:
Numer 1, 2021
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5045123
Autorzy:
Spacirova, Zuzana; Galera, Emilia Ramos; Espin, Jaime
Opublikowane w:
Numer 2, 2021
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5044869
Autorzy:
Oliva-Moreno, Juan; Rodríguez-Sánchez, Beatriz; Peña-Longobardo, Luz María; Aranda-Reneo, Isaac; López-Bastida, Julio
Opublikowane w:
Numer 5, 2021
Wydawca:
IMPACT HTA
DOI:
10.5281/zenodo.5040612
Autorzy:
Karen M. Facey, Piia Rannanheimo, Laura Batchelor, Marine Borchardt, Jo de Cock
Opublikowane w:
International Journal of Technology Assessment in Health Care, Numer 36/4, 2020, Strona(/y) 459-468, ISSN 0266-4623
Wydawca:
Cambridge University Press
DOI:
10.1017/s026646232000063x
Autorzy:
Leticia García-Mochón, Joan Rovira Forns, Jaime Espin
Opublikowane w:
Cost Effectiveness and Resource Allocation, Numer 19/1, 2021, ISSN 1478-7547
Wydawca:
BioMed Central
DOI:
10.1186/s12962-021-00294-4
Autorzy:
Michela Meregaglia, Elena Nicod, Michael Drummond
Opublikowane w:
International Journal of Technology Assessment in Health Care, Numer 36/5, 2020, Strona(/y) 469-473, ISSN 0266-4623
Wydawca:
Cambridge University Press
DOI:
10.1017/s0266462320000665
Autorzy:
Michela Meregaglia, Amanda Whittal, Elena Nicod, Michael Drummond
Opublikowane w:
PharmacoEconomics, Numer 38/6, 2020, Strona(/y) 557-574, ISSN 1170-7690
Wydawca:
Adis International Ltd.
DOI:
10.1007/s40273-020-00897-4
Autorzy:
L. M. Peña-Longobardo, B. Rodríguez-Sánchez, J. Oliva-Moreno, I. Aranda-Reneo, J. López-Bastida
Opublikowane w:
The European Journal of Health Economics, Numer 20/8, 2019, Strona(/y) 1207-1236, ISSN 1618-7598
Wydawca:
Springer Verlag
DOI:
10.1007/s10198-019-01087-6
Autorzy:
Isaac Aranda-Reneo, Beatriz Rodríguez-Sánchez, Luz María Peña-Longobardo, Juan Oliva-Moreno, Julio López-Bastida
Opublikowane w:
Value in Health, Numer 24/3, 2021, Strona(/y) 431-442, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2020.10.014
Autorzy:
Adriano Grossi, Ilda Hoxhaj, Irene Gabutti, Maria Lucia Specchia, Americo Cicchetti, Stefania Boccia, Chiara de Waure
Opublikowane w:
BMC Health Services Research, Numer 21/1, 2021, ISSN 1472-6963
Wydawca:
BioMed Central
DOI:
10.1186/s12913-021-06423-2
Autorzy:
Beatriz Rodriguez-Sanchez, Isaac Aranda-Reneo, Juan Oliva-Moreno, Julio Lopez-Bastida
Opublikowane w:
ClinicoEconomics and Outcomes Research, Numer Volume 13, 2021, Strona(/y) 307-334, ISSN 1178-6981
Wydawca:
Dove Medical Press Limited
DOI:
10.2147/ceor.s301589
Autorzy:
Valentina Prevolnik Rupel, Marko Ogorevc
Opublikowane w:
PharmacoEconomics, Numer 39/4, 2021, Strona(/y) 463-471, ISSN 1170-7690
Wydawca:
Adis International Ltd.
DOI:
10.1007/s40273-020-00994-4
Autorzy:
Juliane Andrea Duevel, Lena Hasemann, Luz María Peña-Longobardo, Beatriz Rodríguez-Sánchez, Isaac Aranda-Reneo, Juan Oliva-Moreno, Julio López-Bastida, Wolfgang Greiner
Opublikowane w:
Health Economics Review, Numer 10/1, 2020, ISSN 2191-1991
Wydawca:
Springer
DOI:
10.1186/s13561-020-00288-7
Autorzy:
Elena Nicod, Amanda Whittal, Michael Drummond, Karen Facey
Opublikowane w:
Orphanet Journal of Rare Diseases, Numer 15/1, 2020, ISSN 1750-1172
Wydawca:
BioMed Central
DOI:
10.1186/s13023-020-01462-0
Autorzy:
Amanda Whittal, Elena Nicod, Mike Drummond, Karen Facey
Opublikowane w:
International Journal of Technology Assessment in Health Care, Numer 37/1, 2021, ISSN 0266-4623
Wydawca:
Cambridge University Press
DOI:
10.1017/s0266462321000337
Autorzy:
Hugo Arlegui, Gaëlle Nachbaur, Nicolas Praet, Bernard Bégaud, J. Jaime Caro
Opublikowane w:
Clinical Therapeutics, Numer 42/10, 2020, Strona(/y) 1983-1991.e2, ISSN 0149-2918
Wydawca:
Excerpta Medica, Inc.
DOI:
10.1016/j.clinthera.2020.08.013
Autorzy:
Valentina Prevolnik Rupel, Juan M. Ramos-Goñi, Marko Ogorevc, Simone Kreimeier, Kristina Ludwig, Wolfgang Greiner
Opublikowane w:
Value in Health, 2021, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2021.03.019
Autorzy:
J. Espin, D. Epstein, A. Gaggero, J. Rovira
Opublikowane w:
Value in Health, Numer 23, 2020, Strona(/y) S648, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2020.08.1470
Autorzy:
Amanda Whittal, Michela Meregaglia, Elena Nicod
Opublikowane w:
The Patient - Patient-Centered Outcomes Research, 2021, ISSN 1178-1653
Wydawca:
Adis International Ltd.
DOI:
10.1007/s40271-020-00493-w
Autorzy:
Valentina Prevolnik Rupel, Marko Ogorevc
Opublikowane w:
Health and Quality of Life Outcomes, Numer 18/1, 2020, ISSN 1477-7525
Wydawca:
BioMed Central
DOI:
10.1186/s12955-020-01584-w
Autorzy:
Elettra Carini, Irene Gabutti, Emanuela Maria Frisicale, Andrea Di Pilla, Angelo Maria Pezzullo, Chiara de Waure, Americo Cicchetti, Stefania Boccia, Maria Lucia Specchia
Opublikowane w:
BMC Health Services Research, Numer 20/1, 2020, ISSN 1472-6963
Wydawca:
BioMed Central
DOI:
10.1186/s12913-020-05879-y
Autorzy:
Kristina Ludwig, Juan M. Ramos-Goñi, Mark Oppe, Simone Kreimeier, Wolfgang Greiner
Opublikowane w:
Value in Health, 2021, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2021.02.012
Autorzy:
Karen M. Facey, Jaime Espin, Emma Kent, Angèl Link, Elena Nicod, Aisling O’Leary, Entela Xoxi, Inneke van de Vijver, Anna Zaremba, Tatyana Benisheva, Andrius Vagoras, Sheela Upadhyaya
Opublikowane w:
PharmacoEconomics, 2021, ISSN 1170-7690
Wydawca:
Adis International Ltd.
DOI:
10.1007/s40273-021-01050-5
Autorzy:
Ramos-Goñi JM, Oppe M, Estévez-Carrillo A, Rivero-Arias O, Wolfgang G, Kreimeier S, Ludwig K, Rupel V
Opublikowane w:
Value in Health, 2021, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2021.10.013
Autorzy:
Mónica D. Oliveira, Inês Mataloto, Panos Kanavos
Opublikowane w:
The European Journal of Health Economics, 2019, Strona(/y) 1-28, ISSN 1618-7598
Wydawca:
Springer Verlag
DOI:
10.1007/s10198-019-01052-3
Autorzy:
Gabutti I
Opublikowane w:
International Journal of Technology, Policy and Management, 2020, ISSN 1468-4322
Wydawca:
Inderscience Publishers
DOI:
10.21203/rs.3.rs-109606/v1
Autorzy:
Zuzana Špacírová, David Epstein, Leticia García-Mochón, Joan Rovira, Antonio Olry de Labry Lima, Jaime Espín
Opublikowane w:
The European Journal of Health Economics, Numer 21/4, 2020, Strona(/y) 529-542, ISSN 1618-7598
Wydawca:
Springer Verlag
DOI:
10.1007/s10198-019-01157-9
Autorzy:
J. Lopez-Bastida, A. Cicchetti, B. Rodríguez-Sánchez, S. Daugbjerg, L.M. Peña-Longobardo, I. Aranda-Reneo, J. Oliva-Moreno
Opublikowane w:
Value in Health, Numer 23, 2020, Strona(/y) S628-S629, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2020.08.1360
Autorzy:
J. Lopez-Bastida, J.A. Düvel, L. Hasemann, L.M. Peña-Longobardo, B. Rodríguez-Sánchez, I. Aranda-Reneo, J. Oliva-Moreno, W. Greiner
Opublikowane w:
Value in Health, Numer 23, 2020, Strona(/y) S586, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2020.08.1092
Autorzy:
J. Lopez-Bastida, B. Rodríguez-Sánchez, I. Aranda-Reneo, J. Oliva-Moreno
Opublikowane w:
Value in Health, Numer 23, 2020, Strona(/y) S511-S512, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2020.08.632
Autorzy:
J. Lopez Bastida, I. Aranda-Reneo, L.M. Peña-Longobardo, B. Rodríguez-Sánchez, J. Oliva-Moreno
Opublikowane w:
Value in Health, Numer 22, 2019, Strona(/y) S844, ISSN 1098-3015
Wydawca:
Blackwell Publishing Inc.
DOI:
10.1016/j.jval.2019.09.2350
Autorzy:
Carlos A. Bana e Costa, Ana C.L. Vieira, Mónica D. Oliveira, João Bana e Costa
Opublikowane w:
EMC-ICDSST 2019 Proceedings – online version Euro mini international conference on decision support system technology, 2019, Strona(/y) 136-140
Wydawca:
P.S. Freitas, F. Dargam, R. Ribeiro, J.M. Moreno, J. Papathanasiou (editors)
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