Cellular innovation driving nervous system evolution

Project Information

NeuralCellTypeEvo

Grant agreement ID: 788921

DOI

10.3030/788921

Project closed

EC signature date 30 May 2018

Start date 1 June 2018

End date 31 May 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (17)

A lamprey neural cell type atlas illuminates the origins of the vertebrate brain

Author(s): Francesco Lamanna, Francisca Hervas-Sotomayor, A. Phillip Oel, David Jandzik, Daniel Sobrido-Cameán, Gabriel N. Santos-Durán, Megan L. Martik, Jan Stundl, Stephen A. Green, Thoomke Brüning, Katharina Mößinger, Julia Schmidt, Celine Schneider, Mari Sepp, Florent Murat, Jeramiah J. Smith, Marianne E. Bronner, María Celina Rodicio, Antón Barreiro-Iglesias, Daniel M. Medeiros, Detlev Arendt, He
Published in: Nat Ecol Evol., 2023, ISSN 2397-334X
Publisher: Springer Nature
DOI: 10.1038/s41559-023-02170-1

Elementary nervous systems

Author(s): Detlev Arendt
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 376/1821, 2021, Page(s) 20200347, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2020.0347

Cross-phyla protein annotation by structural prediction and alignment

Author(s): Fabian Ruperti; Nikolaos Papadopoulos; Jacob M. Musser; Milot Mirdita; Martin Steinegger; Detlev Arendt
Published in: Genome Biology, Vol 24, Iss 1, Pp 1-21 (2023), Issue 5, 2023, ISSN 1465-6906
Publisher: Springer Nature
DOI: 10.1186/s13059-023-02942-9

MorphoFeatures for unsupervised exploration of cell types, tissues, and organs in volume electron microscopy

Author(s): Valentyna Zinchenko, Johannes Hugger, Virginie Uhlmann, Detlev Arendt, and Anna Kreshuk
Published in: elife, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.80918

Molecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response

Author(s): Fabian Ruperti, Isabelle Becher, Anniek Stokkermans, Ling Wang, Nick Marschlich, Clement Potel, Emanuel Maus, Frank Stein, Bernhard Drotleff, Klaske J. Schippers, Michael Nickel, Robert Prevedel, Jacob M. Musser, Mikhail M. Savitski, Detlev Arendt
Published in: Current Biology, 2024, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2023.12.021

The conserved core of the nereid brain: Circular CNS, apical nervous system and lhx6-arx-dlx neurons

Author(s): Detlev Arendt, Idoia Quintana Urzainqui, Hernando Martínez Vergara
Published in: Current Opinion in Neurobiology, 2021, ISSN 0959-4388
Publisher: Elsevier BV
DOI: 10.1016/j.conb.2021.11.008

The Nereid on the rise: Platynereis as a model system.

Author(s): B. Duygu Özpolat; Nadine Randel; Elizabeth A Williams; Luis A Bezares-Calderón; Gabriele Andreatta; Guillaume Balavoine; Paola Bertucci; David E. K. Ferrier; Maria Cristina Gambi; Eve Gazave; Mette Handberg-Thorsager; Jörg D. Hardege; Cameron Hird; Yu-Wen Hsieh; Jerome H.L. Hui; Kevin Nzumbi Mutemi; Stephan Schneider; Oleg Simakov; Hernando Martínez Vergara; Michel Vervoort; Gáspár Jékely;
Published in: EvoDevo, 2021, ISSN 2041-9139
Publisher: BioMed Central
DOI: 10.17863/cam.78076

The Evolutionary Assembly of Neuronal Machinery

Author(s): Detlev Arendt
Published in: Current Biology, Issue 30/10, 2020, Page(s) R603-R616, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2020.04.008

Evolution of neuronal types and families

Author(s): Detlev Arendt, Paola Yanina Bertucci, Kaia Achim, Jacob M Musser
Published in: Current Opinion in Neurobiology, Issue 56, 2019, Page(s) 144-152, ISSN 0959-4388
Publisher: Elsevier BV
DOI: 10.1016/j.conb.2019.01.022

Mapping single-cell atlases throughout Metazoa unravels cell type evolution

Author(s): Tarashanksy, A. J., Musser, J. M., Khariton, M., Li, P., Arendt, D., Quake, S. R., Wang, B.
Published in: eLife, Issue eLife 2021;10:e66747, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.1101/2020.09.28.317784

The dorsoanterior brain of adult amphioxus shares similarities in expression profile and neuronal composition with the vertebrate telencephalon

Author(s): Èlia Benito-Gutiérrez, Manuel Stemmer, Silvia D Rohr, Laura N Schuhmacher, Jocelyn Tang, Aleksandra Marconi, Gáspár Jékely, Detlev Arendt
Published in: BMC Biology, Issue 2021 May 21;19(1):110, 2021, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1101/307629

MoBIE: a Fiji plugin for sharing and exploration of multi-modal cloud-hosted big image data.

Author(s): Constantin Pape, Kimberly Meechan, Ekaterina Moreva, Martin Schorb, Nicolas Chiaruttini, Valentyna Zinchenko, Hernando Martinez Vergara, Giulia Mizzon, Josh Moore, Detlev Arendt, Anna Kreshuk, Yannick Schwab, Christian Tischer
Published in: Nature Methods, 2023, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-023-01776-4

Profiling cellular diversity in sponges informs animal cell type and nervous system evolution

Author(s): Jacob M. Musser, Klaske J. Schippers, Michael Nickel, Giulia Mizzon, Andrea B. Kohn,Constantin Pape, Paolo Ronchi, Nikolaos Papadopoulos, Alexander J. Tarashansky,Jörg U. Hammel, Florian Wolf, Cong Liang, Ana Hernández-Plaza, Carlos P. Cantalapiedra,Kaia Achim, Nicole L. Schieber, Leslie Pan, Fabian Ruperti1,, Warren R. Francis, Sergio Vargas,Svenja Kling, Maike Renkert, Maxim Polikarpov,, Gleb
Published in: Science, 2021, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1101/758276

Whole-body integration of gene expression and single-cell morphology

Author(s): Vergara, H. M., Pape, C., Meechan, K. I., Zinchenko, V., Genoud, C., Wanner, A. A., Titze, B., Templin, R. M., Bertucci, P. Y., Simakov, O., Machado, P., Savage, E. L., Schwab, Y., Friedrich, R. W., Kreshuk, A., Tischer, C., Arendt, D.
Published in: Cell, Issue Cell, 184, 1-19, 2020, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1101/2020.02.26.961037

Many Ways to Build a Polyp

Author(s): Detlev Arendt
Published in: Trends in Genetics, Issue 35/12, 2019, Page(s) 885-887, ISSN 0168-9525
Publisher: Elsevier BV
DOI: 10.1016/j.tig.2019.09.003

Single cell RNA sequencing of the Strongylocentrotus purpuratus larva reveals the blueprint of major cell types and nervous system of a non-chordate deuterostome.

Author(s): Periklis Paganos; Danila Voronov; Jacob M. Musser; Detlev Arendt; Maria Ina Arnone
Published in: eLife, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.70416

Characterization of eyes, photoreceptors, and opsins in developmental stages of the arrow worm Spadella cephaloptera (Chaetognatha)

Author(s): Tim Wollesen, Sonia V. Rodriguez Monje, Adam P. Oel, Detlev Arendt
Published in: J Exp Zool B Mol Dev Evol, 2023, ISSN 1552-5007
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/jez.b.23193

Other (6)

Beyond sequence similarity: cross-phyla protein annotation by structural prediction and alignment

Author(s): Fabian Ruperti, Nikolaos Papadopoulos, Jacob Musser, Milot Mirdita, Martin Steinegger, Detlev Arendt
Published in: Biorxiv, 2022
Publisher: Cold Spring Harbor
DOI: 10.1101/2022.07.05.498892

Single cell RNA sequencing of the Strongylocentrotus purpuratus larva reveals the blueprint of major cell types and nervous system of a non-chordate deuterostome

Author(s): Paganos, P., Voronov, D., Musser, J. M. Arendt, D., Arnone, M. I
Published in: bioXriv, 2021
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.03.16.435574

MorphoFeatures: unsupervised exploration of cell types, tissues and organs in volume electron microscopy

Author(s): Valentyna Zinchenko, Johannes Hugger, Virginie Uhlmann, Detlev Arendt, Anna Kreshuk
Published in: BioRxiv, 2022
Publisher: CSHL
DOI: 10.1101/2022.05.07.490949

Characterization of eyes, photoreceptors and opsins in developmental stages of the chaetognath Spadella cephaloptera

Author(s): Tim Wollesena, Sonia Victoria Rodríguez Monje, Adam Phillip Oel, and Detlev Arendt
Published in: bioXriv, 2019
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/871111

MoBIE: A Fiji plugin for sharing and exploration of multi-modal cloud-hosted big image data

Author(s): Constantin Pape, Kimberly Meechan, Ekaterina Moreva, Martin Schorb, Nicolas Chiaruttini, Valentyna Zinchenko, Hernando Vergara, Giulia Mizzon, Josh Moore, Detlev Arendt, Anna Kreshuk, Yannick Schwab, Christian Tischer
Published in: BioRxiv, 2022
Publisher: CSHL
DOI: 10.1101/2022.05.27.493763

Reconstructing the ancestral vertebrate brain using a lamprey neural cell type atlas

Author(s): Francesco Lamanna, Francisca Hervas-Sotomayor, A. Phillip Oel, David Jandzik, Daniel Sobrido-Cameán, Megan L. Martik, Stephen A. Green, Thoomke Brüning, Katharina Mößinger, Julia Schmidt, Celine Schneider, Mari Sepp, Florent Murat, Jeramiah J. Smith, Marianne E. Bronner, María Celina Rodicio, Antón Barreiro-Iglesias, Daniel M. Medeiros, Detlev Arendt, Henrik Kaessmann.
Published in: Biorxiv, 2022
Publisher: Cold Spring Harbor
DOI: 10.1101/2022.02.28.482278