Transgenerational epigenetic inheritance of chromatin states : the role of Polycomb and 3D chromosome architecture

Project Information

3DEpi

Grant agreement ID: 788972

DOI 10.3030/788972

EC signature date 5 June 2018

Start date 1 November 2018

End date 31 October 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 500 000,00

EU contribution € 2 500 000,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

Publications

Peer reviewed articles (7)

Higher-Order Chromosomal Structures Mediate Genome Function

Author(s): Ivana Jerković, Quentin Szabo, Frédéric Bantignies, Giacomo Cavalli
Published in: Journal of Molecular Biology, Issue 432/3, 2020, Page(s) 676-681, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2019.10.014

Principles of genome folding into topologically associating domains

Author(s): Quentin Szabo, Frédéric Bantignies, Giacomo Cavalli
Published in: Science Advances, Issue 5/4, 2019, Page(s) eaaw1668, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aaw1668

Widespread activation of developmental gene expression characterized by PRC1-dependent chromatin looping

Author(s): V. Loubiere, G. L. Papadopoulos, Q. Szabo, A-M. Martinez, G. Cavalli
Published in: Science Advances, Issue 6/2, 2020, Page(s) eaax4001, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.aax4001

Advances in epigenetics link genetics to the environment and disease

Author(s): Giacomo Cavalli, Edith Heard
Published in: Nature, Issue 571/7766, 2019, Page(s) 489-499, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-019-1411-0

4D Genome Rewiring during Oncogene-Induced and Replicative Senescence

Author(s): Satish Sati, Boyan Bonev, Quentin Szabo, Daniel Jost, Paul Bensadoun, Francois Serra, Vincent Loubiere, Giorgio Lucio Papadopoulos, Juan-Carlos Rivera-Mulia, Lauriane Fritsch, Pauline Bouret, David Castillo, Josep Ll. Gelpi, Modesto Orozco, Cedric Vaillant, Franck Pellestor, Frederic Bantignies, Marc A. Marti-Renom, David M. Gilbert, Jean-Marc Lemaitre, Giacomo Cavalli
Published in: Molecular Cell, Issue 78/3, 2020, Page(s) 522-538.e9, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.03.007

Regulation of single-cell genome organization into TADs and chromatin nanodomains

Author(s): Quentin Szabo, Axelle Donjon, Ivana Jerković, Giorgio L. Papadopoulos, Thierry Cheutin, Boyan Bonev, Elphège P. Nora, Benoit G. Bruneau, Frédéric Bantignies, Giacomo Cavalli
Published in: Nature Genetics, Issue 52/11, 2020, Page(s) 1151-1157, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-020-00716-8

Understanding 3D genome organization by multidisciplinary methods

Author(s): Ivana Jerkovic´, Giacomo Cavalli
Published in: Nature Reviews Molecular Cell Biology, 2021, ISSN 1471-0072
Publisher: Nature Publishing Group
DOI: 10.1038/s41580-021-00362-w