RNA regulation during viral infection

Project Information

VIRUSES AND RNA

Grant agreement ID: 802899

DOI

10.3030/802899

Project closed

EC signature date 11 October 2018

Start date 1 July 2019

End date 30 June 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice

Author(s): Brown AJ, Won JJ, Wolfisberg R, Fahnøe U, Catanzaro N, West A, Moreira FR, Nogueira Batista M, Ferris MT, Linnertz CL, Leist SR, Nguyen C, De la Cruz G, Midkiff BR, Xia Y, Evangelista MD, Montgomery SA, Billerbeck E, Bukh J, Scheel TKH, Rice CM, Sheahan TP.
Published in: Hepatology, Issue 79(1), 2023, Page(s) 183-197, ISSN 0270-9139
Publisher: John Wiley & Sons Inc.
DOI: 10.1097/hep.0000000000000547

Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection

Author(s): Nicolas Fossat; Emma A. Lundsgaard; Rui Costa; Lizandro R. Rivera-Rangel; Louise Nielsen; Lotte S. Mikkelsen; Santseharay Ramirez; Jens Bukh; Troels K.H. Scheel
Published in: Cell Reports, Issue 42(4), 2023, Page(s) 112282, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.112282

Pathogenesis, MicroRNA-122 Gene-Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection`

Author(s): Joy E. Tomlinson, Raphael Wolfisberg, Ulrik Fahnøe, Roosheel S. Patel, Sheetal Trivedi, Arvind Kumar, Himanshu Sharma, Louise Nielsen, Sean P. McDonough, Jens Bukh, Bud C. Tennant, Amit Kapoor, Brad R. Rosenberg, Charles M. Rice, Thomas J. Divers, Gerlinde R. Van de Walle, Troels K.H. Scheel
Published in: Hepatology, Issue 74 (3), 2021, Page(s) 1148-1163, ISSN 1527-3350
Publisher: John Wiley & Sons
DOI: 10.1002/hep.31802

Hepatitis C virus RNA is 5'-capped with flavin adenine dinucleotide

Author(s): Anna V. Sherwood, Lizandro R. Rivera-Rangel, Line A. Ryberg, Helena S. Larsen, Klara M. Anker, Rui Costa, Cathrine B. Vågbø, Eva Jakljevič, Long V. Pham, Carlota Fernandez-Antunez, Gabriele Indrisiunaite, Agnieszka Podolska-Charlery, Julius E. R. Grothen, Nicklas W. Langvad, Nicolas Fossat, Anna Offersgaard, Amal Al-Chaer, Louise Nielsen, Anna Kuśnierczyk, Christina Sølund, Nina Weis, Judith
Published in: Nature, Issue 619(7971), 2023, Page(s) 811-818, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-06301-3

Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington’s disease

Author(s): Meeli Mullari; Nicolas Fossat; Niels H. Skotte; Andrea Asenjo-Martinez; David T. Humphreys; Jens Bukh; Agnete Kirkeby; Troels K. H. Scheel; Michael L. Nielsen
Published in: Nature Communications, Issue 14(1), 2023, Page(s) 4348, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39936-x

Replicons of a Rodent Hepatitis C Model Virus Permit Selection of Highly Permissive Cells

Author(s): Raphael Wolfisberg, Kenn Holmbeck, Louise Nielsen, Amit Kapoor, Charles M. Rice, Jens Bukh, Troels K. H. Scheel
Published in: Journal of Virology, Issue 93/19, 2019, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.00733-19

A Distinct Dexamethasone-Dependent Gene Expression Profile in the Lungs of COVID-19 Patients

Author(s): Ulrik Fahnøe, Andreas Ronit, Ronan M G Berg, Sofie E Jørgensen, Trine H Mogensen, Alexander P Underwood, Troels K H Scheel, Jens Bukh, Ronni R Plovsing
Published in: Journal of Infectious Diseases, Issue 226(12), 2022, Page(s) 2137-2141, ISSN 0022-1899
Publisher: University of Chicago Press
DOI: 10.1093/infdis/jiac218

Evolutionary selection of pestivirus variants with altered or no microRNA dependency

Author(s): Konstantinos G Kokkonos, Nicolas Fossat, Louise Nielsen, Christina Holm, Wytske M Hepkema, Jens Bukh, Troels K H Scheel
Published in: Nucleic Acids Research, Issue 48/10, 2020, Page(s) 5555-5571, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkaa300

Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

Author(s): Raphael Wolfisberg; Kenn Holmbeck; Eva Billerbeck; Caroline E. Thorselius; Mariana N. Batista; Ulrik Fahnøe; Emma A. Lundsgaard; Matthew J. Kennedy; Louise Nielsen; Charles M. Rice; Jens Bukh; Troels K. H. Scheel
Published in: Journal of Virology, Issue 97(4), 2023, Page(s) e0181222, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.01812-22

Neutralization and receptor use of infectious culture–derived rat hepacivirus as a model for HCV

Author(s): Raphael Wolfisberg; Caroline E. Thorselius; Eduardo Salinas; Elizabeth Elrod; Sheetal Trivedi; Louise Nielsen; Ulrik Fahnøe; Amit Kapoor; Arash Grakoui; Charles M. Rice; Jens Bukh; Kenn Holmbeck; Troels K. H. Scheel
Published in: Hepatology, Issue 76(5), 2022, Page(s) 1506-1519, ISSN 1527-3350
Publisher: John Wiley & Sons
DOI: 10.1002/hep.32535

Functional Interplay between RNA Viruses and Non-Coding RNA in Mammals

Author(s): Nkerorema Djodji Damas, Nicolas Fossat, Troels K. H. Scheel
Published in: Non-Coding RNA, Issue 5/1, 2019, Page(s) 7, ISSN 2311-553X
Publisher: MDPI
DOI: 10.3390/ncrna5010007