Targeted microbubble vibrations to accurately diagnose and treat cardiac device-related bacterial biofilm infections

Informazioni relative al progetto

BUBBLE CURE

ID dell’accordo di sovvenzione: 805308

DOI

10.3030/805308

Progetto chiuso

Data della firma CE 5 Novembre 2018

Data di avvio 1 Gennaio 2019

Data di completamento 30 Giugno 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 878 000,00

Contributo UE

€ 1 878 000,00

Coordinato da

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (12)

Early Fibrin Biofilm Development in Cardiovascular Infections

Autori: Safae Oukrich, Jane Hong, Mariël Leon-Grooters, Wiggert van Cappellen, Johan A. Slotman, Gijsje H. Koenderink, Willem J.B. van Wamel, Moniek P.M. de Maat, Klazina Kooiman, Kirby R. Lattwein
Pubblicato in: Biofilm, 2026, ISSN 2590-2075
Editore: Elsevier
DOI: 10.1101/2024.09.02.610803

Native valve, prosthetic valve, and cardiac device-related infective endocarditis: A review and update on current innovative diagnostic and therapeutic strategies

Autori: Joop J. P. Kouijzer; Daniëlle J. Noordermeer; Wouter J. van Leeuwen; Nelianne J. Verkaik; Kirby R. Lattwein
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 10 - 2022, 2022, Pagina/e 10:995508, ISSN 2296-634X
Editore: Frontiers Media SA
DOI: 10.3389/fcell.2022.995508

Vancomycin-decorated microbubbles as a theranostic agent for Staphylococcus aureus biofilms

Autori: Joop J.P. Kouijzer, Kirby R. Lattwein, Inés Beekers, Simone A.G. Langeveld, Mariël Leon-Grooters, Jean-Marc Strub, Estefania Oliva, Gaëtan L.A. Mislin, Nico de Jong, Antonius F.W. van der Steen, Alexander L. Klibanov, Willem J.B. van Wamel, Klazina Kooiman
Pubblicato in: International Journal of Pharmaceutics, Numero 609, 2021, Pagina/e 121154, ISSN 0378-5173
Editore: Elsevier BV
DOI: 10.1016/j.ijpharm.2021.121154

Production of Stable Monodisperse Phospholipid-coated Microbubbles at Room Temperature Using a Microfluidic Flow-focusing Device

Autori: Yuchen Wang, Benjamin R. G. Johnson, Klazina Kooiman
Pubblicato in: Journal of Visualized Experiments, 2025, ISSN 1940-087X
Editore: MYJoVE Corporation
DOI: 10.3791/68796

Dispersing and Sonoporating Biofilm-Associated Bacteria with Sonobactericide

Autori: Kirby R. Lattwein; Inés Beekers; Joop J. P. Kouijzer; Mariël Leon-Grooters; Simone A. G. Langeveld; Tom van Rooij; Antonius F. W. van der Steen; Nico de Jong; Willem J. B. van Wamel; Klazina Kooiman
Pubblicato in: Pharmaceutics, Numero 14, 2022, Pagina/e 1164, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14061164

Shape oscillation and 3-D microstreaming profile of a phospholipid-coated microbubble attached to a wall

Autori: Hongchen Li, Yuchen Wang, Ruisheng Su, Christian Cierpka, Michel Versluis, Antonius F. W. Van Der Steen, Nico De Jong, Martin D. Verweij, Klazina Kooiman
Pubblicato in: IEEE Transactions on Ultrasonics, 2026, Pagina/e 1-1, ISSN 3066-9464
Editore: Institute of Electrical and Electronics Engineers (IEEE)
DOI: 10.1109/tuson.2026.3676695

Coupling Two Ultra-high-Speed Cameras to Elucidate Ultrasound Contrast-Mediated Imaging and Therapy

Autori: Hongchen Li, Xiufeng Li, Gonzalo Collado-Lara, Kirby R. Lattwein, Frits Mastik, Robert Beurskens, Antonius F.W. van der Steen, Martin D. Verweij, Nico de Jong, Klazina Kooiman
Pubblicato in: Ultrasound in Medicine & Biology, Numero 49, 2025, Pagina/e 388-397, ISSN 0301-5629
Editore: Elsevier BV
DOI: 10.1016/j.ultrasmedbio.2022.08.020

Influence of Pluronic F68 on size stability and acoustic behavior of monodisperse phospholipid-coated microbubbles produced at room temperature

Autori: Yuchen Wang, Sander Spiekhout, Ana Walgode, Gonzalo Collado-Lara, Antonius van der Steen, Nico de Jong, Johannes Bosch, Benjamin Johnson, Klazina Kooiman
Pubblicato in: ACS Applied Materials & Interfaces, 2026, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.26434/chemrxiv-2024-z79r9

Nondestructive Ultrasound Molecular Imaging With Higher Order Singular Value Decomposition

Autori: Gonzalo Collado-Lara, Geraldi Wahyulaksana, Hendrik J. Vos, Klazina Kooiman
Pubblicato in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Numero 72, 2025, Pagina/e 1095-1107, ISSN 0885-3010
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2025.3578895

Ultrasonic Characterization of Ibidi <i>μ</i>-Slide I Luer Channel Slides for Studies With Ultrasound Contrast Agents

Autori: Reza Pakdaman Zangabad; Hongchen Li; Joop J. P. Kouijzer; Simone A. G. Langeveld; Inés Beekers; Martin Verweij; Nico De Jong; Klazina Kooiman
Pubblicato in: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Numero 70, 2023, Pagina/e 422 - 429, ISSN 0885-3010
Editore: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tuffc.2023.3250202

Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery

Autori: Klazina Kooiman, Silke Roovers, Simone A.G. Langeveld, Robert T. Kleven, Heleen Dewitte, Meaghan A. O'Reilly, Jean-Michel Escoffre, Ayache Bouakaz, Martin D. Verweij, Kullervo Hynynen, Ine Lentacker, Eleanor Stride, Christy K. Holland
Pubblicato in: Ultrasound in Medicine & Biology, Numero 46/6, 2020, Pagina/e 1296-1325, ISSN 0301-5629
Editore: Elsevier BV
DOI: 10.1016/j.ultrasmedbio.2020.01.002

Dependence of endothelial drug delivery on monodisperse microbubble dynamics

Autori: Yuchen Wang, Hongchen Li, Bram Meijlink, Robert Beurskens, Benjamin R.G. Johnson, Klazina Kooiman
Pubblicato in: Journal of Controlled Release, Numero 384, 2026, Pagina/e 113867, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2025.113867

Non-peer reviewed articles (3)

Microbubble-mediated adjunct treatment for cardiovascular bacterial infections

Autori: Kirby R. Lattwein, Margot E. Starrenburg, Joop J. Kouijzer, Mariël Leon-Grooters, Moniek P. de Maat, Willem J. van Wamel, Klazina Kooiman
Pubblicato in: The Journal of the Acoustical Society of America, Numero 151, 2023, Pagina/e A154-A154, ISSN 0001-4966
Editore: Acoustical Society of America
DOI: 10.1121/10.0010948

Microstreaming profile of a phospholipid-coated wall-attached microbubble undergoing shape oscillation

Autori: Hongchen Li, Yuchen Wang, Ruisheng Su, Christian Cierpka, Michel Versluis, Antonius F. van der Steen, Martin D. Verweij, Nico de Jong, Klazina Kooiman
Pubblicato in: The Journal of the Acoustical Society of America, Numero 155, 2024, Pagina/e A135-A135, ISSN 0001-4966
Editore: Acoustical Society of America
DOI: 10.1121/10.0027070

Monodisperse microbubble-mediated drug delivery: Influence of microbubbles size on drug delivery outcome

Autori: Yuchen Wang, Hongchen Li, Bram Meijlink, Jiali Luo, Robert Beurskens, Benjamin Johnson, Klazina Kooiman
Pubblicato in: The Journal of the Acoustical Society of America, Numero 155, 2024, Pagina/e A325-A325, ISSN 0001-4966
Editore: Acoustical Society of America
DOI: 10.1121/10.0027679

Thesis and dissertations (3)

Microbubble Oscillations and Microstreaming for Local Drug Delivery (PhD thesis)

Autori: Hongchen Li
Pubblicato in: 2026, ISBN 9789465343594
Editore: ProefschriftMaken

Early pathophysiology of Staphylococcus aureus fibrin biofilms (Master graduation thesis)

Autori: Safae Oukrich
Pubblicato in: 2023
Editore: VUmc School of Medical Sciences

Theranostic microbubbles for cardiovascular infections (PhD thesis)

Autori: Joop Kouijzer
Pubblicato in: 2023, ISBN 9789464732504
Editore: Ipskamp Printing