Resultado final Documents, reports (6) Report from Conference on Integrative Metagenomics Report from Conference on IntegrativeMetagenomics Organized summer school at BIOCEV Organized summer school at BIOCEV Report on organized courses Computational Genomics Report on organized courses Computational Genomics Organized Advanced course in metagenomics and OMICs data integration Organized Advanced course in metagenomics and OMICs data integration Dissemination and Communication strategy document prepared Dissemination and Communication strategy document prepared Report on organized courses Methods of Functional Genomics Report on organized courses Methods of FunctionalGenomics Websites, patent fillings, videos etc. (1) MiCoBion webpage developed MiCoBion webpage developed Publicaciones Peer reviewed articles (31) Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention Autores: Arbon, D; Zeniskova, K; Mach, J; Grechnikova, M; Malych, R; Talacko, P; Sutak, R Publicado en: PLOS NEGLECTED TROPICAL DISEASES, 2020, ISSN 1935-2735 Editor: Public Library of Science DOI: 10.1371/journal.pntd.0007759 Cytidine nucleoside analog is an effective antiviral drug against Trichomonasvirus Autores: Narayanasamy, RK; Rada, P; Zdrha, A; van Ranst, M; Neyts, J; Tachezy, J Publicado en: JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2022, ISSN 1684-1182 Editor: Elsevier Taiwan DOI: 10.1016/j.jmii.2021.08.008 Copper Metabolism in Naegleria gruberi and Its Deadly Relative Naegleria fowleri Autores: Kateřina Ženíšková; Maria Grechnikova; Robert Sutak Publicado en: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, Issue 9, 2022, ISSN 2296-634X Editor: Frontiers Media S.A. DOI: 10.3389/fcell.2022.853463 Late Pleistocene Expansion of Small Murid Rodents across the Palearctic in Relation to the Past Environmental Changes Autores: Kozyra, K; Zajac, TM; Ansorge, H; Wierzbicki, H; Moska, M; Stanko, M; Stopka, P Publicado en: GENES, 2021, ISSN 2073-4425 Editor: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/genes12050642 Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases Autores: Zimmann, N; Rada, P; Zarsky, V; Smutna, T; Zahonova, K; Dacks, J; Harant, K; Hrdy, I; Tachezy, J Publicado en: MOLECULAR & CELLULAR PROTEOMICS, 2022, ISSN 1535-9484 Editor: American Society for Biochemistry and Molecular Biology DOI: 10.1016/j.mcpro.2021.100174 Copper detoxification machinery of the brain-eating amoeba Naegleria fowleri involves copper-translocating ATPase and the antioxidant system Autores: Grechnikova, M; Zeniskova, K; Malych, R; Mach, J; Sutak, R Publicado en: INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, 2020, ISSN 2211-3207 Editor: Elsevier BV DOI: 10.1016/j.ijpddr.2020.10.001 The iron-sulfur scaffold protein HCF101 unveils the complexity of organellar evolution in SAR, Haptista and Cryptista Autores: Pyrih, J; Zarsky, V; Fellows, JD; Grosche, C; Wloga, D; Striepen, B; Maier, UG; Tachezy, J Publicado en: BMC ECOLOGY AND EVOLUTION, 2021, ISSN 2730-7182 Editor: BioMed Central DOI: 10.1186/s12862-021-01777-x Perspectives: SARS-CoV-2 Spike Convergent Evolution as a Guide to Explore Adaptive Advantage Autores: Zahradnik, J; Nunvar, J; Schreiber, G Publicado en: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, ISSN 2235-2988 Editor: Frontiers Media S. A. DOI: 10.3389/fcimb.2022.748948 The Virome of Healthy Honey Bee Colonies: Ubiquitous Occurrence of Known and New Viruses in Bee Populations Autores: Kadleckova, D; Tachezy, R; Erban, T; Deboutte, W; Nunvar, J; Salakova, M; Matthijnssens, J Publicado en: MSYSTEMS, 2022, ISSN 2379-5077 Editor: American Society for Microbiology DOI: 10.1128/msystems.00072-22 Iron in parasitic protists - from uptake to storage and where we can interfere. Autores: Jan Mach; Robert Sutak Publicado en: METALLOMICS, Issue 8, 2020, ISSN 1756-5901 Editor: Royal Society of Chemistry DOI: 10.1039/d0mt00125b Flow cytometry-based study of model marine microalgal consortia revealed an ecological advantage of siderophore utilization by the dinoflagellate Amphidinium carterae Autores: Malych, R; Stopka, P; Mach, J; Kotabova, E; Prasil, O; Sutak, R Publicado en: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2022, ISSN 2001-0370 Editor: Elsevier DOI: 10.1016/j.csbj.2021.12.023 Orthohantaviruses in Reservoir and Atypical Hosts in the Czech Republic: Spillover Infection and Indication of Virus-Specific Tissue Tropism Autores: Václav Hönig; Jan Kamiš; Aneta Maršíková; Tereza Matějková; Pavel Stopka; Anna Mácová; Daniel Růžek; Jana Kvičerová Publicado en: MICROBIOLOGY SPECTRUM, Issue 8, 2022, ISSN 2165-0497 Editor: American Society for Microbiology DOI: 10.1128/spectrum.01306-22 Do all mice smell the same? Chemosensory cues from inbred and wild mouse strains elicit stereotypic sensory representations in the accessory olfactory bulb. Autores: Rohini Bansal; Maximilian Nagel; Romana Stopková; Yizhak Sofer; Tali Kimchi; Pavel Stopka; Marc Spehr; Yoram Ben-Shaul Publicado en: BMC biology 19(1), 133 (2021). doi:10.1186/s12915-021-01064-7, Issue 3, 2021, ISSN 1741-7007 Editor: BioMed Central DOI: 10.18154/rwth-2021-07103 The Mastigamoeba balamuthi genome and the nature of the free-living ancestor of Entamoeba Autores: Žárský V., Klimeš V., Pačes J., Vlček Č, Hradilová M., Beneš V., Nývltová E., Hrdý I., Pyrih J, Mach J., Barlow L., Stairs C.W., Eme L., Hall N., Eliáš M., Dacks BJ, Roger A., Tachezy J. Publicado en: Mol Biol Evol. 2021 Jun; 38(6): 2240–2259, 2021, ISSN 1537-1719 Editor: Oxford University Press, Society for Molecular Biology and Evolution DOI: 10.1093/molbev/msab020 Oral and vaginal microbiota in selected field mice of the genus Apodemus: a wild population study Autores: Matejkova, T; Hajkova, P; Stopkova, R; Stanko, M; Martin, JF; Kreisinger, J; Stopka, P Publicado en: SCIENTIFIC REPORTS, 2020, ISSN 2045-2322 Editor: Nature Publishing Group DOI: 10.1038/s41598-020-70249-x The response of Naegleria gruberi to oxidative stress Autores: Malych, Ronald; Fussy, Zoltan; Zeniskova, Katerina; Arbon, Dominik; Hampl, Vladimir; Hrdy, Ivan; Sutak, Robert Publicado en: METALLOMICS, 2022, ISSN 1756-5901 Editor: Royal Society of Chemistry DOI: 10.1093/mtomcs/mfac009 Phenotypic and Clonal Stability of Antigen-Inexperienced Memory-like T Cells across the Genetic Background, Hygienic Status, and Aging Autores: Moudra, A; Niederlova, V; Novotny, J; Schmiedova, L; Kubovciak, J; Matejkova, T; Drobek, A; Pribikova, M; Stopkova, R; Cizkova, D; Neuwirth, A; Michalik, J; Krizova, K; Hudcovic, T; Kolar, M; Kozakova, H; Kreisinger, J; Stopka, P; Stepanek, O Publicado en: JOURNAL OF IMMUNOLOGY, 2021, ISSN 0022-1767 Editor: American Association of Immunologists DOI: 10.4049/jimmunol.2001028 Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum Autores: Luboš Voleman, Vladimíra Najdrová, Ásgeir Ástvaldsson, Pavla Tůmová, Elin Einarsson, Zdeněk Švindrych, Guy M. Hagen, Jan Tachezy, Staffan G. Svärd, Pavel Doležal Publicado en: BMC Biology, Issue 15/1, 2017, ISSN 1741-7007 Editor: BioMed Central DOI: 10.1186/s12915-017-0361-y High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive Recombination Autores: Steven Sijmons, Kim Thys, Mirabeau Mbong Ngwese, Ellen Van Damme, Jan Dvorak, Marnix Van Loock, Guangdi Li, Ruth Tachezy, Laurent Busson, Jeroen Aerssens, Marc Van Ranst, Piet Maes Publicado en: Journal of Virology, Issue 89/15, 2015, Page(s) 7673-7695, ISSN 0022-538X Editor: American Society for Microbiology DOI: 10.1128/JVI.00578-15 A Novel Protein, Ubiquitous in Marine Phytoplankton, Concentrates Iron at the Cell Surface and Facilitates Uptake Autores: Joe Morrissey, Robert Sutak, Javier Paz-Yepes, Atsuko Tanaka, Ahmed Moustafa, Alaguraj Veluchamy, Yann Thomas, Hugo Botebol, François-Yves Bouget, Jeffrey B. McQuaid, Leila Tirichine, Andrew E. Allen, Emmanuel Lesuisse, Chris Bowler Publicado en: Current Biology, Issue 25/3, 2015, Page(s) 364-371, ISSN 0960-9822 Editor: Cell Press DOI: 10.1016/j.cub.2014.12.004 A Eukaryote without a Mitochondrial Organelle Autores: Anna Karnkowska, Vojtěch Vacek, Zuzana Zubáčová, Sebastian C. Treitli, Romana Petrželková, Laura Eme, Lukáš Novák, Vojtěch Žárský, Lael D. Barlow, Emily K. Herman, Petr Soukal, Miluše Hroudová, Pavel Doležal, Courtney W. Stairs, Andrew J. Roger, Marek Eliáš, Joel B. Dacks, Čestmír Vlček, Vladimír Hampl Publicado en: Current Biology, Issue 26/10, 2016, Page(s) 1274-1284, ISSN 0960-9822 Editor: Cell Press DOI: 10.1016/j.cub.2016.03.053 Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function Autores: Anas Khawaja, Vaclav Vopalensky, Martin Pospisek Publicado en: Wiley Interdisciplinary Reviews: RNA, Issue 6/2, 2015, Page(s) 211-224, ISSN 1757-7004 Editor: John Wiley and Sons Inc. DOI: 10.1002/wrna.1268 Lateral Gene Transfer and Gene Duplication Played a Key Role in the Evolution of Mastigamoeba balamuthi Hydrogenosomes Autores: Eva Nývltová, Courtney W. Stairs, Ivan Hrdý, Jakub Rídl, Jan Mach, Jan Pačes, Andrew J. Roger, Jan Tachezy Publicado en: Molecular Biology and Evolution, Issue 32/4, 2015, Page(s) 1039-1055, ISSN 0737-4038 Editor: Oxford University Press DOI: 10.1093/molbev/msu408 Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells Autores: Lan-Feng Dong, Jaromira Kovarova, Martina Bajzikova, Ayenachew Bezawork-Geleta, David Svec, Berwini Endaya, Karishma Sachaphibulkij, Ana R Coelho, Natasa Sebkova, Anna Ruzickova, An S Tan, Katarina Kluckova, Kristyna Judasova, Katerina Zamecnikova, Zuzana Rychtarcikova, Vinod Gopalan, Ladislav Andera, Margarita Sobol, Bing Yan, Bijay Pattnaik, Naveen Bhatraju, Jaroslav Truksa, Pavel Stopka, Pavel Publicado en: eLife, Issue 6, 2017, ISSN 2050-084X Editor: eLife Sciences Publications DOI: 10.7554/eLife.22187 Multilevel regulation of an α-arrestin by glucose depletion controls hexose transporter endocytosis Autores: Junie Hovsepian, Quentin Defenouillère, Véronique Albanèse, Libuše Váchová, Camille Garcia, Zdena Palková, Sébastien Léon Publicado en: The Journal of Cell Biology, Issue 216/6, 2017, Page(s) 1811-1831, ISSN 0021-9525 Editor: Rockefeller University Press DOI: 10.1083/jcb.201610094 Yeast cell differentiation: Lessons from pathogenic and non-pathogenic yeasts Autores: Zdena Palková, Libuše Váchová Publicado en: Seminars in Cell & Developmental Biology, Issue 57, 2016, Page(s) 110-119, ISSN 1084-9521 Editor: Academic Press DOI: 10.1016/j.semcdb.2016.04.006 Cyc8p and Tup1p transcription regulators antagonistically regulate Flo11p expression and complexity of yeast colony biofilms Autores: Phu Van Nguyen, Otakar Hlaváček, Jana Maršíková, Libuše Váchová, Zdena Palková Publicado en: PLOS Genetics, Issue 14/7, 2018, Page(s) e1007495, ISSN 1553-7404 Editor: PLOS DOI: 10.1371/journal.pgen.1007495 Messenger RNAs of Yeast Virus-Like Elements Contain Non-templated 5′ Poly(A) Leaders, and Their Expression Is Independent of eIF4E and Pab1 Autores: Václav Vopálenský, Michal Sýkora, Tomáš Mašek, Martin Pospíšek Publicado en: Frontiers in Microbiology, Issue 10, 2019, ISSN 1664-302X Editor: Frontiers Media DOI: 10.3389/fmicb.2019.02366 Copper and iron metabolism in Ostreococcus tauri – the role of phytotransferrin, plastocyanin and a chloroplast copper-transporting ATPase Autores: Ivo Florin Scheiber, Jana Pilátová, Ronald Malych, Eva Kotabova, Matyáš Krijt, Daniel Vyoral, Jan Mach, Thibaut Léger, Jean-Michel Camadro, Ondřej Prášil, Emmanuel Lesuisse, Robert Sutak Publicado en: Metallomics, Issue 11/10, 2019, Page(s) 1657-1666, ISSN 1756-5901 Editor: Royal Society of Chemistry DOI: 10.1039/c9mt00078j Anaerobic peroxisomes in Mastigamoeba balamuthi Autores: Tien Le, Vojtěch Žárský, Eva Nývltová, Petr Rada, Karel Harant, Marie Vancová, Zdeněk Verner, Ivan Hrdý, Jan Tachezy Publicado en: Proceedings of the National Academy of Sciences, 2019, Page(s) 201909755, ISSN 0027-8424 Editor: National Academy of Sciences DOI: 10.1073/pnas.1909755117 Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol Autores: Verner, Z; Zarsky, V; Le, T; Narayanasamy, RK; Rada, P; Rozbesky, D; Makki, A; Belisova, D; Hrdy, I; Vancova, M; Lender, C; Konig, C; Bruchhaus, I; Tachezy, J Publicado en: PLOS PATHOGENS, 2021, ISSN 1553-7366 Editor: Public Library of Science DOI: 10.1371/journal.ppat.1010041 Buscando datos de OpenAIRE... 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