Microbial Communities in Biomedical and Environmental Areas, and Systems Biology

Informations projet

MiCoBion

N° de convention de subvention: 810224

DOI

10.3030/810224

Projet clôturé

Date de signature de la CE 6 Juillet 2018

Date de début 1 Septembre 2018

Date de fin 30 Novembre 2022

Financé au titre de

• Twinning of research institutions

Coût total

€ 998 205,00

Contribution de l’UE

€ 998 205,00

Coordonné par

UNIVERZITA KARLOVA
Czechia

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (7)

Report from Conference on Integrative Metagenomics

Report from Conference on IntegrativeMetagenomics

Organized summer school at BIOCEV
Report from Conference on Microbial Communities: Function, Structure and Complexity

Report from Conference on MicrobialCommunities Function Structure and Complexity

Report on organized courses Computational Genomics
Organized Advanced course in metagenomics and OMICs data integration
Dissemination and Communication strategy document prepared

Dissemination and Communication strategy document prepared

Report on organized courses Methods of Functional Genomics

Report on organized courses Methods of FunctionalGenomics

Websites, patent fillings, videos etc. (1)

MiCoBion webpage developed

Publications

Peer reviewed articles (33)

Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention

Auteurs: Arbon, D; Zeniskova, K; Mach, J; Grechnikova, M; Malych, R; Talacko, P; Sutak, R
Publié dans: PLOS NEGLECTED TROPICAL DISEASES, 2020, ISSN 1935-2735
Éditeur: Public Library of Science
DOI: 10.1371/journal.pntd.0007759

Cytidine nucleoside analog is an effective antiviral drug against Trichomonasvirus

Auteurs: Narayanasamy, RK; Rada, P; Zdrha, A; van Ranst, M; Neyts, J; Tachezy, J
Publié dans: JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2022, ISSN 1684-1182
Éditeur: Elsevier Taiwan
DOI: 10.1016/j.jmii.2021.08.008

Copper Metabolism in Naegleria gruberi and Its Deadly Relative Naegleria fowleri

Auteurs: Kateřina Ženíšková; Maria Grechnikova; Robert Sutak
Publié dans: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, Numéro 9, 2022, ISSN 2296-634X
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fcell.2022.853463

Late Pleistocene Expansion of Small Murid Rodents across the Palearctic in Relation to the Past Environmental Changes

Auteurs: Kozyra, K; Zajac, TM; Ansorge, H; Wierzbicki, H; Moska, M; Stanko, M; Stopka, P
Publié dans: GENES, 2021, ISSN 2073-4425
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12050642

Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases

Auteurs: Zimmann, N; Rada, P; Zarsky, V; Smutna, T; Zahonova, K; Dacks, J; Harant, K; Hrdy, I; Tachezy, J
Publié dans: MOLECULAR & CELLULAR PROTEOMICS, 2022, ISSN 1535-9484
Éditeur: American Society for Biochemistry and Molecular Biology
DOI: 10.1016/j.mcpro.2021.100174

Copper detoxification machinery of the brain-eating amoeba Naegleria fowleri involves copper-translocating ATPase and the antioxidant system

Auteurs: Grechnikova, M; Zeniskova, K; Malych, R; Mach, J; Sutak, R
Publié dans: INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, 2020, ISSN 2211-3207
Éditeur: Elsevier BV
DOI: 10.1016/j.ijpddr.2020.10.001

The iron-sulfur scaffold protein HCF101 unveils the complexity of organellar evolution in SAR, Haptista and Cryptista

Auteurs: Pyrih, J; Zarsky, V; Fellows, JD; Grosche, C; Wloga, D; Striepen, B; Maier, UG; Tachezy, J
Publié dans: BMC ECOLOGY AND EVOLUTION, 2021, ISSN 2730-7182
Éditeur: BioMed Central
DOI: 10.1186/s12862-021-01777-x

Perspectives: SARS-CoV-2 Spike Convergent Evolution as a Guide to Explore Adaptive Advantage

Auteurs: Zahradnik, J; Nunvar, J; Schreiber, G
Publié dans: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, ISSN 2235-2988
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fcimb.2022.748948

The Virome of Healthy Honey Bee Colonies: Ubiquitous Occurrence of Known and New Viruses in Bee Populations

Auteurs: Kadleckova, D; Tachezy, R; Erban, T; Deboutte, W; Nunvar, J; Salakova, M; Matthijnssens, J
Publié dans: MSYSTEMS, 2022, ISSN 2379-5077
Éditeur: American Society for Microbiology
DOI: 10.1128/msystems.00072-22

Iron in parasitic protists - from uptake to storage and where we can interfere.

Auteurs: Jan Mach; Robert Sutak
Publié dans: METALLOMICS, Numéro 8, 2020, ISSN 1756-5901
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d0mt00125b

Biological Roles of Lipocalins in Chemical Communication, Reproduction, and Regulation of Microbiota

Auteurs: Stopkova, R; Otcenaskova, T; Matejkova, T; Kuntova, B; Stopka, P
Publié dans: FRONTIERS IN PHYSIOLOGY, 2021, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.740006

Comparison of plasma and cerebrospinal fluid proteomes identifies gene products guiding adult neurogenesis and neural differentiation in birds.

Auteurs: Eleni Voukali; Nithya Kuttiyarthu Veetil; Pavel Němec; Pavel Stopka; Michal Vinkler
Publié dans: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021), Numéro 6, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.21203/rs.3.rs-138227/v1

Flow cytometry-based study of model marine microalgal consortia revealed an ecological advantage of siderophore utilization by the dinoflagellate Amphidinium carterae

Auteurs: Malych, R; Stopka, P; Mach, J; Kotabova, E; Prasil, O; Sutak, R
Publié dans: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2022, ISSN 2001-0370
Éditeur: Elsevier
DOI: 10.1016/j.csbj.2021.12.023

Orthohantaviruses in Reservoir and Atypical Hosts in the Czech Republic: Spillover Infection and Indication of Virus-Specific Tissue Tropism

Auteurs: Václav Hönig; Jan Kamiš; Aneta Maršíková; Tereza Matějková; Pavel Stopka; Anna Mácová; Daniel Růžek; Jana Kvičerová
Publié dans: MICROBIOLOGY SPECTRUM, Numéro 8, 2022, ISSN 2165-0497
Éditeur: American Society for Microbiology
DOI: 10.1128/spectrum.01306-22

Do all mice smell the same? Chemosensory cues from inbred and wild mouse strains elicit stereotypic sensory representations in the accessory olfactory bulb.

Auteurs: Rohini Bansal; Maximilian Nagel; Romana Stopková; Yizhak Sofer; Tali Kimchi; Pavel Stopka; Marc Spehr; Yoram Ben-Shaul
Publié dans: BMC biology 19(1), 133 (2021). doi:10.1186/s12915-021-01064-7, Numéro 3, 2021, ISSN 1741-7007
Éditeur: BioMed Central
DOI: 10.18154/rwth-2021-07103

The Mastigamoeba balamuthi genome and the nature of the free-living ancestor of Entamoeba

Auteurs: Žárský V., Klimeš V., Pačes J., Vlček Č, Hradilová M., Beneš V., Nývltová E., Hrdý I., Pyrih J, Mach J., Barlow L., Stairs C.W., Eme L., Hall N., Eliáš M., Dacks BJ, Roger A., Tachezy J.
Publié dans: Mol Biol Evol. 2021 Jun; 38(6): 2240–2259, 2021, ISSN 1537-1719
Éditeur: Oxford University Press, Society for Molecular Biology and Evolution
DOI: 10.1093/molbev/msab020

Oral and vaginal microbiota in selected field mice of the genus Apodemus: a wild population study

Auteurs: Matejkova, T; Hajkova, P; Stopkova, R; Stanko, M; Martin, JF; Kreisinger, J; Stopka, P
Publié dans: SCIENTIFIC REPORTS, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-70249-x

The response of Naegleria gruberi to oxidative stress

Auteurs: Malych, Ronald; Fussy, Zoltan; Zeniskova, Katerina; Arbon, Dominik; Hampl, Vladimir; Hrdy, Ivan; Sutak, Robert
Publié dans: METALLOMICS, 2022, ISSN 1756-5901
Éditeur: Royal Society of Chemistry
DOI: 10.1093/mtomcs/mfac009

Phenotypic and Clonal Stability of Antigen-Inexperienced Memory-like T Cells across the Genetic Background, Hygienic Status, and Aging

Auteurs: Moudra, A; Niederlova, V; Novotny, J; Schmiedova, L; Kubovciak, J; Matejkova, T; Drobek, A; Pribikova, M; Stopkova, R; Cizkova, D; Neuwirth, A; Michalik, J; Krizova, K; Hudcovic, T; Kolar, M; Kozakova, H; Kreisinger, J; Stopka, P; Stepanek, O
Publié dans: JOURNAL OF IMMUNOLOGY, 2021, ISSN 0022-1767
Éditeur: American Association of Immunologists
DOI: 10.4049/jimmunol.2001028

Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum

Auteurs: Luboš Voleman, Vladimíra Najdrová, Ásgeir Ástvaldsson, Pavla Tůmová, Elin Einarsson, Zdeněk Švindrych, Guy M. Hagen, Jan Tachezy, Staffan G. Svärd, Pavel Doležal
Publié dans: BMC Biology, Numéro 15/1, 2017, ISSN 1741-7007
Éditeur: BioMed Central
DOI: 10.1186/s12915-017-0361-y

High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive Recombination

Auteurs: Steven Sijmons, Kim Thys, Mirabeau Mbong Ngwese, Ellen Van Damme, Jan Dvorak, Marnix Van Loock, Guangdi Li, Ruth Tachezy, Laurent Busson, Jeroen Aerssens, Marc Van Ranst, Piet Maes
Publié dans: Journal of Virology, Numéro 89/15, 2015, Page(s) 7673-7695, ISSN 0022-538X
Éditeur: American Society for Microbiology
DOI: 10.1128/JVI.00578-15

A Novel Protein, Ubiquitous in Marine Phytoplankton, Concentrates Iron at the Cell Surface and Facilitates Uptake

Auteurs: Joe Morrissey, Robert Sutak, Javier Paz-Yepes, Atsuko Tanaka, Ahmed Moustafa, Alaguraj Veluchamy, Yann Thomas, Hugo Botebol, François-Yves Bouget, Jeffrey B. McQuaid, Leila Tirichine, Andrew E. Allen, Emmanuel Lesuisse, Chris Bowler
Publié dans: Current Biology, Numéro 25/3, 2015, Page(s) 364-371, ISSN 0960-9822
Éditeur: Cell Press
DOI: 10.1016/j.cub.2014.12.004

A Eukaryote without a Mitochondrial Organelle

Auteurs: Anna Karnkowska, Vojtěch Vacek, Zuzana Zubáčová, Sebastian C. Treitli, Romana Petrželková, Laura Eme, Lukáš Novák, Vojtěch Žárský, Lael D. Barlow, Emily K. Herman, Petr Soukal, Miluše Hroudová, Pavel Doležal, Courtney W. Stairs, Andrew J. Roger, Marek Eliáš, Joel B. Dacks, Čestmír Vlček, Vladimír Hampl
Publié dans: Current Biology, Numéro 26/10, 2016, Page(s) 1274-1284, ISSN 0960-9822
Éditeur: Cell Press
DOI: 10.1016/j.cub.2016.03.053

Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function

Auteurs: Anas Khawaja, Vaclav Vopalensky, Martin Pospisek
Publié dans: Wiley Interdisciplinary Reviews: RNA, Numéro 6/2, 2015, Page(s) 211-224, ISSN 1757-7004
Éditeur: John Wiley and Sons Inc.
DOI: 10.1002/wrna.1268

Lateral Gene Transfer and Gene Duplication Played a Key Role in the Evolution of Mastigamoeba balamuthi Hydrogenosomes

Auteurs: Eva Nývltová, Courtney W. Stairs, Ivan Hrdý, Jakub Rídl, Jan Mach, Jan Pačes, Andrew J. Roger, Jan Tachezy
Publié dans: Molecular Biology and Evolution, Numéro 32/4, 2015, Page(s) 1039-1055, ISSN 0737-4038
Éditeur: Oxford University Press
DOI: 10.1093/molbev/msu408

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

Auteurs: Lan-Feng Dong, Jaromira Kovarova, Martina Bajzikova, Ayenachew Bezawork-Geleta, David Svec, Berwini Endaya, Karishma Sachaphibulkij, Ana R Coelho, Natasa Sebkova, Anna Ruzickova, An S Tan, Katarina Kluckova, Kristyna Judasova, Katerina Zamecnikova, Zuzana Rychtarcikova, Vinod Gopalan, Ladislav Andera, Margarita Sobol, Bing Yan, Bijay Pattnaik, Naveen Bhatraju, Jaroslav Truksa, Pavel Stopka, Pavel
Publié dans: eLife, Numéro 6, 2017, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/eLife.22187

Multilevel regulation of an α-arrestin by glucose depletion controls hexose transporter endocytosis

Auteurs: Junie Hovsepian, Quentin Defenouillère, Véronique Albanèse, Libuše Váchová, Camille Garcia, Zdena Palková, Sébastien Léon
Publié dans: The Journal of Cell Biology, Numéro 216/6, 2017, Page(s) 1811-1831, ISSN 0021-9525
Éditeur: Rockefeller University Press
DOI: 10.1083/jcb.201610094

Yeast cell differentiation: Lessons from pathogenic and non-pathogenic yeasts

Auteurs: Zdena Palková, Libuše Váchová
Publié dans: Seminars in Cell & Developmental Biology, Numéro 57, 2016, Page(s) 110-119, ISSN 1084-9521
Éditeur: Academic Press
DOI: 10.1016/j.semcdb.2016.04.006

Cyc8p and Tup1p transcription regulators antagonistically regulate Flo11p expression and complexity of yeast colony biofilms

Auteurs: Phu Van Nguyen, Otakar Hlaváček, Jana Maršíková, Libuše Váchová, Zdena Palková
Publié dans: PLOS Genetics, Numéro 14/7, 2018, Page(s) e1007495, ISSN 1553-7404
Éditeur: PLOS
DOI: 10.1371/journal.pgen.1007495

Messenger RNAs of Yeast Virus-Like Elements Contain Non-templated 5′ Poly(A) Leaders, and Their Expression Is Independent of eIF4E and Pab1

Auteurs: Václav Vopálenský, Michal Sýkora, Tomáš Mašek, Martin Pospíšek
Publié dans: Frontiers in Microbiology, Numéro 10, 2019, ISSN 1664-302X
Éditeur: Frontiers Media
DOI: 10.3389/fmicb.2019.02366

Copper and iron metabolism in Ostreococcus tauri – the role of phytotransferrin, plastocyanin and a chloroplast copper-transporting ATPase

Auteurs: Ivo Florin Scheiber, Jana Pilátová, Ronald Malych, Eva Kotabova, Matyáš Krijt, Daniel Vyoral, Jan Mach, Thibaut Léger, Jean-Michel Camadro, Ondřej Prášil, Emmanuel Lesuisse, Robert Sutak
Publié dans: Metallomics, Numéro 11/10, 2019, Page(s) 1657-1666, ISSN 1756-5901
Éditeur: Royal Society of Chemistry
DOI: 10.1039/c9mt00078j

Anaerobic peroxisomes in Mastigamoeba balamuthi

Auteurs: Tien Le, Vojtěch Žárský, Eva Nývltová, Petr Rada, Karel Harant, Marie Vancová, Zdeněk Verner, Ivan Hrdý, Jan Tachezy
Publié dans: Proceedings of the National Academy of Sciences, 2019, Page(s) 201909755, ISSN 0027-8424
Éditeur: National Academy of Sciences
DOI: 10.1073/pnas.1909755117

Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol

Auteurs: Verner, Z; Zarsky, V; Le, T; Narayanasamy, RK; Rada, P; Rozbesky, D; Makki, A; Belisova, D; Hrdy, I; Vancova, M; Lender, C; Konig, C; Bruchhaus, I; Tachezy, J
Publié dans: PLOS PATHOGENS, 2021, ISSN 1553-7366
Éditeur: Public Library of Science
DOI: 10.1371/journal.ppat.1010041