Risultati finali Documents, reports (6) Report from Conference on Integrative Metagenomics Report from Conference on IntegrativeMetagenomics Organized summer school at BIOCEV Organized summer school at BIOCEV Report on organized courses Computational Genomics Report on organized courses Computational Genomics Organized Advanced course in metagenomics and OMICs data integration Organized Advanced course in metagenomics and OMICs data integration Dissemination and Communication strategy document prepared Dissemination and Communication strategy document prepared Report on organized courses Methods of Functional Genomics Report on organized courses Methods of FunctionalGenomics Websites, patent fillings, videos etc. (1) MiCoBion webpage developed MiCoBion webpage developed Pubblicazioni Peer reviewed articles (31) Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention Autori: Arbon, D; Zeniskova, K; Mach, J; Grechnikova, M; Malych, R; Talacko, P; Sutak, R Pubblicato in: PLOS NEGLECTED TROPICAL DISEASES, 2020, ISSN 1935-2735 Editore: Public Library of Science DOI: 10.1371/journal.pntd.0007759 Cytidine nucleoside analog is an effective antiviral drug against Trichomonasvirus Autori: Narayanasamy, RK; Rada, P; Zdrha, A; van Ranst, M; Neyts, J; Tachezy, J Pubblicato in: JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2022, ISSN 1684-1182 Editore: Elsevier Taiwan DOI: 10.1016/j.jmii.2021.08.008 Copper Metabolism in Naegleria gruberi and Its Deadly Relative Naegleria fowleri Autori: Kateřina Ženíšková; Maria Grechnikova; Robert Sutak Pubblicato in: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, Issue 9, 2022, ISSN 2296-634X Editore: Frontiers Media S.A. DOI: 10.3389/fcell.2022.853463 Late Pleistocene Expansion of Small Murid Rodents across the Palearctic in Relation to the Past Environmental Changes Autori: Kozyra, K; Zajac, TM; Ansorge, H; Wierzbicki, H; Moska, M; Stanko, M; Stopka, P Pubblicato in: GENES, 2021, ISSN 2073-4425 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/genes12050642 Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases Autori: Zimmann, N; Rada, P; Zarsky, V; Smutna, T; Zahonova, K; Dacks, J; Harant, K; Hrdy, I; Tachezy, J Pubblicato in: MOLECULAR & CELLULAR PROTEOMICS, 2022, ISSN 1535-9484 Editore: American Society for Biochemistry and Molecular Biology DOI: 10.1016/j.mcpro.2021.100174 Copper detoxification machinery of the brain-eating amoeba Naegleria fowleri involves copper-translocating ATPase and the antioxidant system Autori: Grechnikova, M; Zeniskova, K; Malych, R; Mach, J; Sutak, R Pubblicato in: INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE, 2020, ISSN 2211-3207 Editore: Elsevier BV DOI: 10.1016/j.ijpddr.2020.10.001 The iron-sulfur scaffold protein HCF101 unveils the complexity of organellar evolution in SAR, Haptista and Cryptista Autori: Pyrih, J; Zarsky, V; Fellows, JD; Grosche, C; Wloga, D; Striepen, B; Maier, UG; Tachezy, J Pubblicato in: BMC ECOLOGY AND EVOLUTION, 2021, ISSN 2730-7182 Editore: BioMed Central DOI: 10.1186/s12862-021-01777-x Perspectives: SARS-CoV-2 Spike Convergent Evolution as a Guide to Explore Adaptive Advantage Autori: Zahradnik, J; Nunvar, J; Schreiber, G Pubblicato in: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, ISSN 2235-2988 Editore: Frontiers Media S. A. DOI: 10.3389/fcimb.2022.748948 The Virome of Healthy Honey Bee Colonies: Ubiquitous Occurrence of Known and New Viruses in Bee Populations Autori: Kadleckova, D; Tachezy, R; Erban, T; Deboutte, W; Nunvar, J; Salakova, M; Matthijnssens, J Pubblicato in: MSYSTEMS, 2022, ISSN 2379-5077 Editore: American Society for Microbiology DOI: 10.1128/msystems.00072-22 Iron in parasitic protists - from uptake to storage and where we can interfere. Autori: Jan Mach; Robert Sutak Pubblicato in: METALLOMICS, Issue 8, 2020, ISSN 1756-5901 Editore: Royal Society of Chemistry DOI: 10.1039/d0mt00125b Flow cytometry-based study of model marine microalgal consortia revealed an ecological advantage of siderophore utilization by the dinoflagellate Amphidinium carterae Autori: Malych, R; Stopka, P; Mach, J; Kotabova, E; Prasil, O; Sutak, R Pubblicato in: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2022, ISSN 2001-0370 Editore: Elsevier DOI: 10.1016/j.csbj.2021.12.023 Orthohantaviruses in Reservoir and Atypical Hosts in the Czech Republic: Spillover Infection and Indication of Virus-Specific Tissue Tropism Autori: Václav Hönig; Jan Kamiš; Aneta Maršíková; Tereza Matějková; Pavel Stopka; Anna Mácová; Daniel Růžek; Jana Kvičerová Pubblicato in: MICROBIOLOGY SPECTRUM, Issue 8, 2022, ISSN 2165-0497 Editore: American Society for Microbiology DOI: 10.1128/spectrum.01306-22 Do all mice smell the same? Chemosensory cues from inbred and wild mouse strains elicit stereotypic sensory representations in the accessory olfactory bulb. Autori: Rohini Bansal; Maximilian Nagel; Romana Stopková; Yizhak Sofer; Tali Kimchi; Pavel Stopka; Marc Spehr; Yoram Ben-Shaul Pubblicato in: BMC biology 19(1), 133 (2021). doi:10.1186/s12915-021-01064-7, Issue 3, 2021, ISSN 1741-7007 Editore: BioMed Central DOI: 10.18154/rwth-2021-07103 The Mastigamoeba balamuthi genome and the nature of the free-living ancestor of Entamoeba Autori: Žárský V., Klimeš V., Pačes J., Vlček Č, Hradilová M., Beneš V., Nývltová E., Hrdý I., Pyrih J, Mach J., Barlow L., Stairs C.W., Eme L., Hall N., Eliáš M., Dacks BJ, Roger A., Tachezy J. Pubblicato in: Mol Biol Evol. 2021 Jun; 38(6): 2240–2259, 2021, ISSN 1537-1719 Editore: Oxford University Press, Society for Molecular Biology and Evolution DOI: 10.1093/molbev/msab020 Oral and vaginal microbiota in selected field mice of the genus Apodemus: a wild population study Autori: Matejkova, T; Hajkova, P; Stopkova, R; Stanko, M; Martin, JF; Kreisinger, J; Stopka, P Pubblicato in: SCIENTIFIC REPORTS, 2020, ISSN 2045-2322 Editore: Nature Publishing Group DOI: 10.1038/s41598-020-70249-x The response of Naegleria gruberi to oxidative stress Autori: Malych, Ronald; Fussy, Zoltan; Zeniskova, Katerina; Arbon, Dominik; Hampl, Vladimir; Hrdy, Ivan; Sutak, Robert Pubblicato in: METALLOMICS, 2022, ISSN 1756-5901 Editore: Royal Society of Chemistry DOI: 10.1093/mtomcs/mfac009 Phenotypic and Clonal Stability of Antigen-Inexperienced Memory-like T Cells across the Genetic Background, Hygienic Status, and Aging Autori: Moudra, A; Niederlova, V; Novotny, J; Schmiedova, L; Kubovciak, J; Matejkova, T; Drobek, A; Pribikova, M; Stopkova, R; Cizkova, D; Neuwirth, A; Michalik, J; Krizova, K; Hudcovic, T; Kolar, M; Kozakova, H; Kreisinger, J; Stopka, P; Stepanek, O Pubblicato in: JOURNAL OF IMMUNOLOGY, 2021, ISSN 0022-1767 Editore: American Association of Immunologists DOI: 10.4049/jimmunol.2001028 Giardia intestinalis mitosomes undergo synchronized fission but not fusion and are constitutively associated with the endoplasmic reticulum Autori: Luboš Voleman, Vladimíra Najdrová, Ásgeir Ástvaldsson, Pavla Tůmová, Elin Einarsson, Zdeněk Švindrych, Guy M. Hagen, Jan Tachezy, Staffan G. Svärd, Pavel Doležal Pubblicato in: BMC Biology, Issue 15/1, 2017, ISSN 1741-7007 Editore: BioMed Central DOI: 10.1186/s12915-017-0361-y High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive Recombination Autori: Steven Sijmons, Kim Thys, Mirabeau Mbong Ngwese, Ellen Van Damme, Jan Dvorak, Marnix Van Loock, Guangdi Li, Ruth Tachezy, Laurent Busson, Jeroen Aerssens, Marc Van Ranst, Piet Maes Pubblicato in: Journal of Virology, Issue 89/15, 2015, Page(s) 7673-7695, ISSN 0022-538X Editore: American Society for Microbiology DOI: 10.1128/JVI.00578-15 A Novel Protein, Ubiquitous in Marine Phytoplankton, Concentrates Iron at the Cell Surface and Facilitates Uptake Autori: Joe Morrissey, Robert Sutak, Javier Paz-Yepes, Atsuko Tanaka, Ahmed Moustafa, Alaguraj Veluchamy, Yann Thomas, Hugo Botebol, François-Yves Bouget, Jeffrey B. McQuaid, Leila Tirichine, Andrew E. Allen, Emmanuel Lesuisse, Chris Bowler Pubblicato in: Current Biology, Issue 25/3, 2015, Page(s) 364-371, ISSN 0960-9822 Editore: Cell Press DOI: 10.1016/j.cub.2014.12.004 A Eukaryote without a Mitochondrial Organelle Autori: Anna Karnkowska, Vojtěch Vacek, Zuzana Zubáčová, Sebastian C. Treitli, Romana Petrželková, Laura Eme, Lukáš Novák, Vojtěch Žárský, Lael D. Barlow, Emily K. Herman, Petr Soukal, Miluše Hroudová, Pavel Doležal, Courtney W. Stairs, Andrew J. Roger, Marek Eliáš, Joel B. Dacks, Čestmír Vlček, Vladimír Hampl Pubblicato in: Current Biology, Issue 26/10, 2016, Page(s) 1274-1284, ISSN 0960-9822 Editore: Cell Press DOI: 10.1016/j.cub.2016.03.053 Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function Autori: Anas Khawaja, Vaclav Vopalensky, Martin Pospisek Pubblicato in: Wiley Interdisciplinary Reviews: RNA, Issue 6/2, 2015, Page(s) 211-224, ISSN 1757-7004 Editore: John Wiley and Sons Inc. DOI: 10.1002/wrna.1268 Lateral Gene Transfer and Gene Duplication Played a Key Role in the Evolution of Mastigamoeba balamuthi Hydrogenosomes Autori: Eva Nývltová, Courtney W. Stairs, Ivan Hrdý, Jakub Rídl, Jan Mach, Jan Pačes, Andrew J. Roger, Jan Tachezy Pubblicato in: Molecular Biology and Evolution, Issue 32/4, 2015, Page(s) 1039-1055, ISSN 0737-4038 Editore: Oxford University Press DOI: 10.1093/molbev/msu408 Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells Autori: Lan-Feng Dong, Jaromira Kovarova, Martina Bajzikova, Ayenachew Bezawork-Geleta, David Svec, Berwini Endaya, Karishma Sachaphibulkij, Ana R Coelho, Natasa Sebkova, Anna Ruzickova, An S Tan, Katarina Kluckova, Kristyna Judasova, Katerina Zamecnikova, Zuzana Rychtarcikova, Vinod Gopalan, Ladislav Andera, Margarita Sobol, Bing Yan, Bijay Pattnaik, Naveen Bhatraju, Jaroslav Truksa, Pavel Stopka, Pavel Pubblicato in: eLife, Issue 6, 2017, ISSN 2050-084X Editore: eLife Sciences Publications DOI: 10.7554/eLife.22187 Multilevel regulation of an α-arrestin by glucose depletion controls hexose transporter endocytosis Autori: Junie Hovsepian, Quentin Defenouillère, Véronique Albanèse, Libuše Váchová, Camille Garcia, Zdena Palková, Sébastien Léon Pubblicato in: The Journal of Cell Biology, Issue 216/6, 2017, Page(s) 1811-1831, ISSN 0021-9525 Editore: Rockefeller University Press DOI: 10.1083/jcb.201610094 Yeast cell differentiation: Lessons from pathogenic and non-pathogenic yeasts Autori: Zdena Palková, Libuše Váchová Pubblicato in: Seminars in Cell & Developmental Biology, Issue 57, 2016, Page(s) 110-119, ISSN 1084-9521 Editore: Academic Press DOI: 10.1016/j.semcdb.2016.04.006 Cyc8p and Tup1p transcription regulators antagonistically regulate Flo11p expression and complexity of yeast colony biofilms Autori: Phu Van Nguyen, Otakar Hlaváček, Jana Maršíková, Libuše Váchová, Zdena Palková Pubblicato in: PLOS Genetics, Issue 14/7, 2018, Page(s) e1007495, ISSN 1553-7404 Editore: PLOS DOI: 10.1371/journal.pgen.1007495 Messenger RNAs of Yeast Virus-Like Elements Contain Non-templated 5′ Poly(A) Leaders, and Their Expression Is Independent of eIF4E and Pab1 Autori: Václav Vopálenský, Michal Sýkora, Tomáš Mašek, Martin Pospíšek Pubblicato in: Frontiers in Microbiology, Issue 10, 2019, ISSN 1664-302X Editore: Frontiers Media DOI: 10.3389/fmicb.2019.02366 Copper and iron metabolism in Ostreococcus tauri – the role of phytotransferrin, plastocyanin and a chloroplast copper-transporting ATPase Autori: Ivo Florin Scheiber, Jana Pilátová, Ronald Malych, Eva Kotabova, Matyáš Krijt, Daniel Vyoral, Jan Mach, Thibaut Léger, Jean-Michel Camadro, Ondřej Prášil, Emmanuel Lesuisse, Robert Sutak Pubblicato in: Metallomics, Issue 11/10, 2019, Page(s) 1657-1666, ISSN 1756-5901 Editore: Royal Society of Chemistry DOI: 10.1039/c9mt00078j Anaerobic peroxisomes in Mastigamoeba balamuthi Autori: Tien Le, Vojtěch Žárský, Eva Nývltová, Petr Rada, Karel Harant, Marie Vancová, Zdeněk Verner, Ivan Hrdý, Jan Tachezy Pubblicato in: Proceedings of the National Academy of Sciences, 2019, Page(s) 201909755, ISSN 0027-8424 Editore: National Academy of Sciences DOI: 10.1073/pnas.1909755117 Anaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol Autori: Verner, Z; Zarsky, V; Le, T; Narayanasamy, RK; Rada, P; Rozbesky, D; Makki, A; Belisova, D; Hrdy, I; Vancova, M; Lender, C; Konig, C; Bruchhaus, I; Tachezy, J Pubblicato in: PLOS PATHOGENS, 2021, ISSN 1553-7366 Editore: Public Library of Science DOI: 10.1371/journal.ppat.1010041 È in corso la ricerca di dati su OpenAIRE... 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