Peroxisome Interactions and Communication

Información del proyecto

PERICO

Identificador del acuerdo de subvención: 812968

DOI

10.3030/812968

Proyecto cerrado

Fecha de la firma de la CE 30 Agosto 2018

Fecha de inicio 1 Octubre 2018

Fecha de finalización 31 Marzo 2023

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 3 974 527,44

Aportación de la UE

€ 3 974 527,44

Coordinado por

RIJKSUNIVERSITEIT GRONINGEN
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Other (7)

Researcher Declarations on Conformity
All ESRs are recruited
4.3 Awards of doctoral degrees

Awards of doctoral degrees. For universities with PhD programmes of 4 years (Netherlands and Belgium) and 4.5 years (Israel) this will be achieved only at months 54 and 60, respectively.

"4.2 Conference organisation ""Peroxisome Interactions and Communication"""

Conference organisation “Peroxisome Interactions and Communication”

4.1 Training School including scientific and transferable skills courses

Training Schools including scientific and transferable skills courses organized

PERICO vacancies advertised
5.1 Project website

Project website

Documents, reports (2)

5.5 Education Programme Report

Education Programme Report

5.6 Public dissemination of project results after protection

Public dissemination of project results after protection

Publicaciones

Book chapters (7)

Assessment of the Peroxisomal Redox State in Living Cells Using NADPH- and NAD+/NADH-Specific Fluorescent Protein Sensors

Autores: Cláudio F Costa Hongli Li Mohamed A F Hussein Yi Yang Celien Lismont Marc Fransen
Publicado en: Methods in Molecular Biology, Edición 2643, 2023, Página(s) 183-197, ISBN 978-1-0716-3048-8
Editor: Humana
DOI: 10.1007/978-1-0716-3048-8_13

Isolation of Glycosomes from Trypanosoma brucei

Autores: Krishna, C.K., Franke, L., Erdmann, R., Kalel, V.C.
Publicado en: Methods in Molecular Biology book series (MIMB, volume 2643), 2023, ISBN 978-1-0716-3048-8
Editor: Humana, New York, NY
DOI: 10.1007/978-1-0716-3048-8_3

Identification of Peroxisome-Derived Hydrogen Peroxide-Sensitive Target Proteins Using a YAP1C-Based Genetic Probe

Autores: Celien Lismont Iulia Revenco Cláudio F Costa Hongli Li Mohamed A F Hussein Paul P Van Veldhoven Rita Derua Marc Fransen
Publicado en: Methods in Molecular Biology, Edición 2643, 2023, Página(s) 161-181, ISBN 978-1-0716-3048-8
Editor: Humana
DOI: 10.1007/978-1-0716-3048-8_12

Applying CRISPR-Cas9 Genome Editing to Study Genes Involved in Peroxisome Biogenesis or Peroxisomal Functions

Autores: Chornyi S, Koster J, Waterham HR
Publicado en: Methods Mol Biol, Edición 2643, 2023, Página(s) 233-245, ISBN 978-1-0716-3047-1
Editor: Humana, New York, NY
DOI: 10.1007/978-1-0716-3048-8_17

Analysis of Yeast Peroxisomes via Spatial Proteomics

Autores: Hirak Das, Alexandros Zografakis, Silke Oeljeklaus, Bettina Warscheid
Publicado en: Methods in Molecular Biology (Peroxisomes: Methods and protocols), Edición Vol. 2643, 2023, Página(s) 13-31, ISBN 978-1-0716-3048-8
Editor: Humana
DOI: 10.1007/978-1-0716-3048-8_2

Peroxisomal Dysfunction and Oxidative Stress in Neurodegenerative Disease: A Bidirectional Crosstalk

Autores: Marc Fransen, Iulia Revenco, Hongli Li, Cláudio F. Costa, Celien Lismont, Paul P. Van Veldhoven
Publicado en: Peroxisome Biology: Experimental Models, Peroxisomal Disorders and Neurological Diseases, Edición 1299, 2020, Página(s) 19-30, ISBN 978-3-030-60203-1
Editor: Springer International Publishing
DOI: 10.1007/978-3-030-60204-8_2

Generation of Reporter Cell Lines for Endogenous Expression Analysis of Peroxisomal Proteins

Autores: Silva, Beatriz S. C.; Schrader, Tina A.; Schrader, Michael; Carmichael, Ruth E.
Publicado en: Methods Mol Biol, Edición 2643, 2023, Página(s) 247-270, ISSN 1940-6029
Editor: Springer
DOI: 10.1007/978-1-0716-3048-8_18

Peer reviewed articles (18)

Organoids as a model to study intestinal and liver dysfunction in severe malnutrition

Autores: José M. Horcas-Nieto, Christian J. Versloot, Miriam Langelaar-Makkinje, Albert Gerding, Tjasso Blokzijl, Mirjam H. Koster, Mirjam Baanstra, Ingrid A. Martini, Robert P. Coppes, Céline Bourdon, Sven C.D. van Ijzendoorn, Peter Kim, Robert H.J. Bandsma, Barbara M. Bakker
Publicado en: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Edición 1869 (3), 2023, ISSN 0925-4439
Editor: Elsevier BV
DOI: 10.1016/j.bbadis.2022.166635

The Peroxisome-Autophagy Redox Connection: A Double-Edged Sword?

Autores: Hongli Li, Celien Lismont, Iulia Revenco, Mohamed A. F. Hussein, Cláudio F. Costa, Marc Fransen
Publicado en: Frontiers in Cell & Developmental Biology, 2021, Página(s) 1-16, ISSN 2296-634X
Editor: Frontiers Media S.A
DOI: 10.3389/fcell.2021.814047

The origin of long-chain fatty acids required for de novo ether lipid/plasmalogen synthesis.

Autores: Chornyi S, Ofman R, Koster J, Waterham HR
Publicado en: J Lipid Res, Edición 100364, 2023, Página(s) In press, ISSN 1539-7262
Editor: American Society for Biochemistry and Molecular Biology
DOI: 10.1016/j.jlr.2023.100364

Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition

Autores: Ling C, Versloot CJ, Arvidsson Kvissberg ME, Hu G, Swain N, Horcas-Nieto JM, Miraglia E, Thind MK, Farooqui A, Gerding A, van Eunen K, Koster MH, Kloosterhuis NJ, Chi L, ChenMi Y, Langelaar-Makkinje M, Bourdon C, Swann J, Smit M, de Bruin A, Youssef SA, Feenstra M, van Dijk TH, Thedieck K, Jonker JW, Kim PK, Bakker BM, Bandsma RHJ
Publicado en: EBioMedicine, Edición 96, 2023, Página(s) 104809, ISSN 2352-3964
Editor: Elsevier BV
DOI: 10.1016/j.ebiom.2023.104809

OrganelX web server for sub-peroxisomal and sub-mitochondrial protein localization and peroxisomal target signal detection

Autores: Marco Anteghini,Asmaa Haja,Vitor A.P. Martins dos Santos,Lambert Schomaker, Edoardo Saccentia
Publicado en: Computational and Structural Biotechnology Journal, Edición 21, 2022, Página(s) 128-133, ISSN 2001-0370
Editor: ScienceDirect
DOI: 10.1016/j.csbj.2022.11.058

Towards automatization of organoid analysis: A deep learning approach to localize and quantify organoid images

Autores: Asmaa Haja, José M. Horcas-Nieto, Barbara M. Bakker, Lambert Schomaker
Publicado en: Computer Methods and Programs in Biomedicine Update, Edición 3, 2023, ISSN 2666-9900
Editor: Elsevier BV
DOI: 10.1016/j.cmpbup.2023.100101

Insights Into the Peroxisomal Protein Inventory of Zebrafish

Autores: Kamoshita, Maki; Kumar, Rechal; Anteghini, Marco; Kunze, Markus; Islinger, Markus; Martins dos Santos, Vítor; Schrader, Michael
Publicado en: Frontiers in Physiology, 2022, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.822509

The peroxisome: an update on mysteries 3.0

Autores: Kumar, Rechal; Islinger, Markus; Worthy, Harley; Carmichael, Ruth; Schrader, Michael
Publicado en: Histochem Cell Biol, Edición 161, 2024, Página(s) 99-132, ISSN 1432-119X
Editor: Springer
DOI: 10.1007/s00418-023-02259-5

Maintaining social contacts: The physiological relevance of organelle interactions

Autores: Beatriz S C Silva, Laura DiGiovanni, Rechal Kumar , Ruth E Carmichael, Peter K Kim, Michael Schrader
Publicado en: Biochim Biophys Acta Mol Cell Res, Edición 1867(11):118800, 2020, ISSN 0167-4889
Editor: Elsevier BV
DOI: 10.1016/j.bbamcr.2020.118800

Differential roles for ACBD4 and ACBD5 in peroxisome–ER interactions and lipid metabolism

Autores: Joseph L. Costello, Janet Koster, Beatriz S.C. Silva, Harley L. Worthy, Tina A. Schrader, Christian Hacker, Josiah Passmore, Frans A. Kuypers, Hans R. Waterham, Michael Schrader
Publicado en: J Biol Chem, Edición 299, 2023, Página(s) 105013, ISSN 1083-351X
Editor: Elsevier
DOI: 10.1016/j.jbc.2023.105013

Enhanced Levels of Peroxisome-Derived H2O2 Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells

Autores: Hongli Li Celien Lismont Cláudio F Costa Mohamed A F Hussein Myriam Baes Marc Fransen
Publicado en: Antioxidants, Edición 12 (613), 2023, Página(s) 1-21, ISSN 2076-3921
Editor: MDPI
DOI: 10.3390/antiox12030613

Peroxisome-Derived Hydrogen Peroxide Modulates the Sulfenylation Profiles of Key Redox Signaling Proteins in Flp-In T-REx 293 Cells

Autores: Celien Lismont, Iulia Revenco, Hongli Li, Cláudio F. Costa, Lisa Lenaerts, Mohamed A. F. Hussein, Jonas De Bie, Bernard Knoops, Paul P. Van Veldhoven, Rita Derua, Marc Fransen
Publicado en: Frontiers in Cell and Developmental Biology, Edición 10:888873, 2022, Página(s) 1-19, ISSN 2296-634X
Editor: Frontiers Media S.A.
DOI: 10.3389/fcell.2022.888873

Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay

Autores: Mira Rosenthal 1, Eyal Metzl-Raz 1, Jérôme Bürgi 2, Eden Yifrach 1, Layla Drwesh 3, Amir Fadel 1, Yoav Peleg 4, Doron Rapaport 3, Matthias Wilmanns 2 5, Naama Barkai 1, Maya Schuldiner 6, Einat Zalckvar 6
Publicado en: PNAS, Edición 117 (35), 2020, Página(s) 21432-21440, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.1920078117

Pex14p Phosphorylation Modulates Import of Citrate Synthase 2 Into Peroxisomes in Saccharomyces cerevisiae.

Autores: Andreas Schummer; Renate Maier; Shiran Gabay-Maskit; Tobias Hansen; Wignand W. D. Mühlhäuser; Ida Suppanz; Amir Fadel; Maya Schuldiner; Wolfgang Girzalsky; Silke Oeljeklaus; Silke Oeljeklaus; Einat Zalckvar; Ralf Erdmann; Bettina Warscheid; Bettina Warscheid
Publicado en: Frontiers in Cell and Developmental Biology, Edición 20, 2020, ISSN 2296-634X
Editor: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.549451

Peroxisomal Hydrogen Peroxide Metabolism and Signaling in Health and Disease

Autores: Lismont, Revenco, Fransen
Publicado en: International Journal of Molecular Sciences, Edición 20/15, 2019, Página(s) 3673, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20153673

DIMA: Data-Driven Selection of an Imputation Algorithm.

Autores: Janine Egert; Eva Brombacher; Bettina Warscheid; Clemens Kreutz
Publicado en: Journal of Proteome Research, Edición 20, 2021, ISSN 1535-3893
Editor: American Chemical Society
DOI: 10.1021/acs.jproteome.1c00119

Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes

Autores: Krishna, Chethan K.; Schmidt, Nadine; Tippler, Bettina G.; Schliebs, Wolfgang; Jung, Martin; Winklhofer, Konstanze F.; Erdmann, Ralf; Kalel, Vishal C.
Publicado en: Frontiers Cell and Developmental Biology, Edición 1, 2023, ISSN 2296-634X
Editor: Frontiers Media SA
DOI: 10.3389/fcell.2023.1213761

Peroxisomal Metabolite and Cofactor Transport in Humans.

Autores: Chornyi S, IJlst L, van Roermund CWT, Wanders RJA, Waterham HR
Publicado en: Front Cell Dev Biol, Edición 8, 2021, Página(s) 613892, ISSN 2296-634X
Editor: Frontiers Media SA
DOI: 10.3389/fcell.2020.613892

Conference proceedings (2)

A Fully Automated End-to-End Process for Fluorescence Microscopy Images of Yeast Cells: From Segmentation to Detection and Classification

Autores: Asmaa Haja, Lambert Schomaker
Publicado en: Proceedings of 2021 International Conference on Medical Imaging and Computer-Aided Diagnosis (MICAD 2021), 2021, Página(s) 10, ISBN 978-981-16-3880-0
Editor: Springer
DOI: 10.1007/978-981-16-3880-0_5

A Comparison of Different U-Net Models for Segmentation of Overlapping Organoids

Autores: Marco Anteghini, Asmaa Haja, Vitor AP Martins dos Santos, Lambert Schomaker, Edoardo Saccenti
Publicado en: ICBBE '22: Proceedings of the 2022 9th International Conference on Biomedical and Bioinformatics Engineering, 2022, Página(s) 1-10
Editor: Association for Computing Machinery (ACM)
DOI: 10.1145/3574198.3574199

Other (3)

Finding Balance: A series of U-Net models forImage Segmentation of Overlapping organoids

Autores: Stefania Radu, Asmaa Haja, Lambert Schomaker
Publicado en: 2022, Página(s) 1-19
Editor: University of Groningen

OrganelX Web Server for Sub-Peroxisomal and Sub-Mitochondrial protein localisation

Autores: Marco Anteghini, Asmaa Haja, Vitor AP Martins dos Santos, Lambert Schomaker, Edoardo Saccenti
Publicado en: bioRxiv, 2022
Editor: bioRxiv
DOI: 10.1101/2022.06.21.497045

PEX1 is essential for the glycosome biogenesis and trypanosomatid parasite survival

Autores: Mahadevan, Lavanya; Arya, Hemant; Schliebs, Wolfgang; Erdmann, Ralf; Kalel, Vishal C.
Publicado en: BioRxiv, Edición 21, 2023, ISSN 2692-8205
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.08.05.550684

Thesis and dissertations (2)

Unravelling the molecular mechanisms of peroxisome-organelle communication and interplay

Autores: Beatriz Silva
Publicado en: 2023
Editor: University of Exeter

Investigation of lipid transporters at the peroxisome-ER interface

Autores: Rechal Kumar
Publicado en: 2023
Editor: University of Exeter