Peroxisome Interactions and Communication

Informazioni relative al progetto

PERICO

ID dell’accordo di sovvenzione: 812968

DOI

10.3030/812968

Progetto chiuso

Data della firma CE 30 Agosto 2018

Data di avvio 1 Ottobre 2018

Data di completamento 31 Marzo 2023

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 3 974 527,44

Contributo UE

€ 3 974 527,44

Coordinato da

RIJKSUNIVERSITEIT GRONINGEN
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (7)

Researcher Declarations on Conformity
All ESRs are recruited
4.3 Awards of doctoral degrees

Awards of doctoral degrees. For universities with PhD programmes of 4 years (Netherlands and Belgium) and 4.5 years (Israel) this will be achieved only at months 54 and 60, respectively.

"4.2 Conference organisation ""Peroxisome Interactions and Communication"""

Conference organisation “Peroxisome Interactions and Communication”

4.1 Training School including scientific and transferable skills courses

Training Schools including scientific and transferable skills courses organized

PERICO vacancies advertised
5.1 Project website

Project website

Documents, reports (2)

5.5 Education Programme Report

Education Programme Report

5.6 Public dissemination of project results after protection

Public dissemination of project results after protection

Pubblicazioni

Book chapters (7)

Assessment of the Peroxisomal Redox State in Living Cells Using NADPH- and NAD+/NADH-Specific Fluorescent Protein Sensors

Autori: Cláudio F Costa Hongli Li Mohamed A F Hussein Yi Yang Celien Lismont Marc Fransen
Pubblicato in: Methods in Molecular Biology, Numero 2643, 2023, Pagina/e 183-197, ISBN 978-1-0716-3048-8
Editore: Humana
DOI: 10.1007/978-1-0716-3048-8_13

Isolation of Glycosomes from Trypanosoma brucei

Autori: Krishna, C.K., Franke, L., Erdmann, R., Kalel, V.C.
Pubblicato in: Methods in Molecular Biology book series (MIMB, volume 2643), 2023, ISBN 978-1-0716-3048-8
Editore: Humana, New York, NY
DOI: 10.1007/978-1-0716-3048-8_3

Identification of Peroxisome-Derived Hydrogen Peroxide-Sensitive Target Proteins Using a YAP1C-Based Genetic Probe

Autori: Celien Lismont Iulia Revenco Cláudio F Costa Hongli Li Mohamed A F Hussein Paul P Van Veldhoven Rita Derua Marc Fransen
Pubblicato in: Methods in Molecular Biology, Numero 2643, 2023, Pagina/e 161-181, ISBN 978-1-0716-3048-8
Editore: Humana
DOI: 10.1007/978-1-0716-3048-8_12

Applying CRISPR-Cas9 Genome Editing to Study Genes Involved in Peroxisome Biogenesis or Peroxisomal Functions

Autori: Chornyi S, Koster J, Waterham HR
Pubblicato in: Methods Mol Biol, Numero 2643, 2023, Pagina/e 233-245, ISBN 978-1-0716-3047-1
Editore: Humana, New York, NY
DOI: 10.1007/978-1-0716-3048-8_17

Analysis of Yeast Peroxisomes via Spatial Proteomics

Autori: Hirak Das, Alexandros Zografakis, Silke Oeljeklaus, Bettina Warscheid
Pubblicato in: Methods in Molecular Biology (Peroxisomes: Methods and protocols), Numero Vol. 2643, 2023, Pagina/e 13-31, ISBN 978-1-0716-3048-8
Editore: Humana
DOI: 10.1007/978-1-0716-3048-8_2

Peroxisomal Dysfunction and Oxidative Stress in Neurodegenerative Disease: A Bidirectional Crosstalk

Autori: Marc Fransen, Iulia Revenco, Hongli Li, Cláudio F. Costa, Celien Lismont, Paul P. Van Veldhoven
Pubblicato in: Peroxisome Biology: Experimental Models, Peroxisomal Disorders and Neurological Diseases, Numero 1299, 2020, Pagina/e 19-30, ISBN 978-3-030-60203-1
Editore: Springer International Publishing
DOI: 10.1007/978-3-030-60204-8_2

Generation of Reporter Cell Lines for Endogenous Expression Analysis of Peroxisomal Proteins

Autori: Silva, Beatriz S. C.; Schrader, Tina A.; Schrader, Michael; Carmichael, Ruth E.
Pubblicato in: Methods Mol Biol, Numero 2643, 2023, Pagina/e 247-270, ISSN 1940-6029
Editore: Springer
DOI: 10.1007/978-1-0716-3048-8_18

Peer reviewed articles (18)

Organoids as a model to study intestinal and liver dysfunction in severe malnutrition

Autori: José M. Horcas-Nieto, Christian J. Versloot, Miriam Langelaar-Makkinje, Albert Gerding, Tjasso Blokzijl, Mirjam H. Koster, Mirjam Baanstra, Ingrid A. Martini, Robert P. Coppes, Céline Bourdon, Sven C.D. van Ijzendoorn, Peter Kim, Robert H.J. Bandsma, Barbara M. Bakker
Pubblicato in: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Numero 1869 (3), 2023, ISSN 0925-4439
Editore: Elsevier BV
DOI: 10.1016/j.bbadis.2022.166635

The Peroxisome-Autophagy Redox Connection: A Double-Edged Sword?

Autori: Hongli Li, Celien Lismont, Iulia Revenco, Mohamed A. F. Hussein, Cláudio F. Costa, Marc Fransen
Pubblicato in: Frontiers in Cell & Developmental Biology, 2021, Pagina/e 1-16, ISSN 2296-634X
Editore: Frontiers Media S.A
DOI: 10.3389/fcell.2021.814047

The origin of long-chain fatty acids required for de novo ether lipid/plasmalogen synthesis.

Autori: Chornyi S, Ofman R, Koster J, Waterham HR
Pubblicato in: J Lipid Res, Numero 100364, 2023, Pagina/e In press, ISSN 1539-7262
Editore: American Society for Biochemistry and Molecular Biology
DOI: 10.1016/j.jlr.2023.100364

Rebalancing of mitochondrial homeostasis through an NAD+-SIRT1 pathway preserves intestinal barrier function in severe malnutrition

Autori: Ling C, Versloot CJ, Arvidsson Kvissberg ME, Hu G, Swain N, Horcas-Nieto JM, Miraglia E, Thind MK, Farooqui A, Gerding A, van Eunen K, Koster MH, Kloosterhuis NJ, Chi L, ChenMi Y, Langelaar-Makkinje M, Bourdon C, Swann J, Smit M, de Bruin A, Youssef SA, Feenstra M, van Dijk TH, Thedieck K, Jonker JW, Kim PK, Bakker BM, Bandsma RHJ
Pubblicato in: EBioMedicine, Numero 96, 2023, Pagina/e 104809, ISSN 2352-3964
Editore: Elsevier BV
DOI: 10.1016/j.ebiom.2023.104809

OrganelX web server for sub-peroxisomal and sub-mitochondrial protein localization and peroxisomal target signal detection

Autori: Marco Anteghini,Asmaa Haja,Vitor A.P. Martins dos Santos,Lambert Schomaker, Edoardo Saccentia
Pubblicato in: Computational and Structural Biotechnology Journal, Numero 21, 2022, Pagina/e 128-133, ISSN 2001-0370
Editore: ScienceDirect
DOI: 10.1016/j.csbj.2022.11.058

Towards automatization of organoid analysis: A deep learning approach to localize and quantify organoid images

Autori: Asmaa Haja, José M. Horcas-Nieto, Barbara M. Bakker, Lambert Schomaker
Pubblicato in: Computer Methods and Programs in Biomedicine Update, Numero 3, 2023, ISSN 2666-9900
Editore: Elsevier BV
DOI: 10.1016/j.cmpbup.2023.100101

Insights Into the Peroxisomal Protein Inventory of Zebrafish

Autori: Kamoshita, Maki; Kumar, Rechal; Anteghini, Marco; Kunze, Markus; Islinger, Markus; Martins dos Santos, Vítor; Schrader, Michael
Pubblicato in: Frontiers in Physiology, 2022, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.822509

The peroxisome: an update on mysteries 3.0

Autori: Kumar, Rechal; Islinger, Markus; Worthy, Harley; Carmichael, Ruth; Schrader, Michael
Pubblicato in: Histochem Cell Biol, Numero 161, 2024, Pagina/e 99-132, ISSN 1432-119X
Editore: Springer
DOI: 10.1007/s00418-023-02259-5

Maintaining social contacts: The physiological relevance of organelle interactions

Autori: Beatriz S C Silva, Laura DiGiovanni, Rechal Kumar , Ruth E Carmichael, Peter K Kim, Michael Schrader
Pubblicato in: Biochim Biophys Acta Mol Cell Res, Numero 1867(11):118800, 2020, ISSN 0167-4889
Editore: Elsevier BV
DOI: 10.1016/j.bbamcr.2020.118800

Differential roles for ACBD4 and ACBD5 in peroxisome–ER interactions and lipid metabolism

Autori: Joseph L. Costello, Janet Koster, Beatriz S.C. Silva, Harley L. Worthy, Tina A. Schrader, Christian Hacker, Josiah Passmore, Frans A. Kuypers, Hans R. Waterham, Michael Schrader
Pubblicato in: J Biol Chem, Numero 299, 2023, Pagina/e 105013, ISSN 1083-351X
Editore: Elsevier
DOI: 10.1016/j.jbc.2023.105013

Enhanced Levels of Peroxisome-Derived H2O2 Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells

Autori: Hongli Li Celien Lismont Cláudio F Costa Mohamed A F Hussein Myriam Baes Marc Fransen
Pubblicato in: Antioxidants, Numero 12 (613), 2023, Pagina/e 1-21, ISSN 2076-3921
Editore: MDPI
DOI: 10.3390/antiox12030613

Peroxisome-Derived Hydrogen Peroxide Modulates the Sulfenylation Profiles of Key Redox Signaling Proteins in Flp-In T-REx 293 Cells

Autori: Celien Lismont, Iulia Revenco, Hongli Li, Cláudio F. Costa, Lisa Lenaerts, Mohamed A. F. Hussein, Jonas De Bie, Bernard Knoops, Paul P. Van Veldhoven, Rita Derua, Marc Fransen
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 10:888873, 2022, Pagina/e 1-19, ISSN 2296-634X
Editore: Frontiers Media S.A.
DOI: 10.3389/fcell.2022.888873

Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay

Autori: Mira Rosenthal 1, Eyal Metzl-Raz 1, Jérôme Bürgi 2, Eden Yifrach 1, Layla Drwesh 3, Amir Fadel 1, Yoav Peleg 4, Doron Rapaport 3, Matthias Wilmanns 2 5, Naama Barkai 1, Maya Schuldiner 6, Einat Zalckvar 6
Pubblicato in: PNAS, Numero 117 (35), 2020, Pagina/e 21432-21440, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1920078117

Pex14p Phosphorylation Modulates Import of Citrate Synthase 2 Into Peroxisomes in Saccharomyces cerevisiae.

Autori: Andreas Schummer; Renate Maier; Shiran Gabay-Maskit; Tobias Hansen; Wignand W. D. Mühlhäuser; Ida Suppanz; Amir Fadel; Maya Schuldiner; Wolfgang Girzalsky; Silke Oeljeklaus; Silke Oeljeklaus; Einat Zalckvar; Ralf Erdmann; Bettina Warscheid; Bettina Warscheid
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 20, 2020, ISSN 2296-634X
Editore: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.549451

Peroxisomal Hydrogen Peroxide Metabolism and Signaling in Health and Disease

Autori: Lismont, Revenco, Fransen
Pubblicato in: International Journal of Molecular Sciences, Numero 20/15, 2019, Pagina/e 3673, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20153673

DIMA: Data-Driven Selection of an Imputation Algorithm.

Autori: Janine Egert; Eva Brombacher; Bettina Warscheid; Clemens Kreutz
Pubblicato in: Journal of Proteome Research, Numero 20, 2021, ISSN 1535-3893
Editore: American Chemical Society
DOI: 10.1021/acs.jproteome.1c00119

Molecular basis of the glycosomal targeting of PEX11 and its mislocalization to mitochondrion in trypanosomes

Autori: Krishna, Chethan K.; Schmidt, Nadine; Tippler, Bettina G.; Schliebs, Wolfgang; Jung, Martin; Winklhofer, Konstanze F.; Erdmann, Ralf; Kalel, Vishal C.
Pubblicato in: Frontiers Cell and Developmental Biology, Numero 1, 2023, ISSN 2296-634X
Editore: Frontiers Media SA
DOI: 10.3389/fcell.2023.1213761

Peroxisomal Metabolite and Cofactor Transport in Humans.

Autori: Chornyi S, IJlst L, van Roermund CWT, Wanders RJA, Waterham HR
Pubblicato in: Front Cell Dev Biol, Numero 8, 2021, Pagina/e 613892, ISSN 2296-634X
Editore: Frontiers Media SA
DOI: 10.3389/fcell.2020.613892

Conference proceedings (2)

A Fully Automated End-to-End Process for Fluorescence Microscopy Images of Yeast Cells: From Segmentation to Detection and Classification

Autori: Asmaa Haja, Lambert Schomaker
Pubblicato in: Proceedings of 2021 International Conference on Medical Imaging and Computer-Aided Diagnosis (MICAD 2021), 2021, Pagina/e 10, ISBN 978-981-16-3880-0
Editore: Springer
DOI: 10.1007/978-981-16-3880-0_5

A Comparison of Different U-Net Models for Segmentation of Overlapping Organoids

Autori: Marco Anteghini, Asmaa Haja, Vitor AP Martins dos Santos, Lambert Schomaker, Edoardo Saccenti
Pubblicato in: ICBBE '22: Proceedings of the 2022 9th International Conference on Biomedical and Bioinformatics Engineering, 2022, Pagina/e 1-10
Editore: Association for Computing Machinery (ACM)
DOI: 10.1145/3574198.3574199

Other (3)

Finding Balance: A series of U-Net models forImage Segmentation of Overlapping organoids

Autori: Stefania Radu, Asmaa Haja, Lambert Schomaker
Pubblicato in: 2022, Pagina/e 1-19
Editore: University of Groningen

OrganelX Web Server for Sub-Peroxisomal and Sub-Mitochondrial protein localisation

Autori: Marco Anteghini, Asmaa Haja, Vitor AP Martins dos Santos, Lambert Schomaker, Edoardo Saccenti
Pubblicato in: bioRxiv, 2022
Editore: bioRxiv
DOI: 10.1101/2022.06.21.497045

PEX1 is essential for the glycosome biogenesis and trypanosomatid parasite survival

Autori: Mahadevan, Lavanya; Arya, Hemant; Schliebs, Wolfgang; Erdmann, Ralf; Kalel, Vishal C.
Pubblicato in: BioRxiv, Numero 21, 2023, ISSN 2692-8205
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.08.05.550684

Thesis and dissertations (2)

Unravelling the molecular mechanisms of peroxisome-organelle communication and interplay

Autori: Beatriz Silva
Pubblicato in: 2023
Editore: University of Exeter

Investigation of lipid transporters at the peroxisome-ER interface

Autori: Rechal Kumar
Pubblicato in: 2023
Editore: University of Exeter