Description du projet
Biocapteurs de glucose implantables avancés
Être capable de surveiller en continu les niveaux in vivo d’analytes tels que le glucose est d’un grand intérêt en médecine, en particulier dans le contexte des maladies chroniques. Cependant, les biocapteurs implantables présentent des défis importants en raison des réponses inflammatoires contre le capteur et de l’environnement dynamique des tissus vivants. L’objectif du projet ImplantSens, financé par l’UE, est de former de jeunes chercheurs dans le domaine des biocapteurs à résoudre ces problèmes technologiques non résolus. L’objectif expérimental du projet est de faire progresser les capteurs de glucose enzymatiques et de combiner des nanomatériaux pour améliorer la biocompatibilité et la précision des capteurs.
Objectif
ImplantSens will develop long‐term stable implantable electrochemical biosensors by overcoming mass‐transport limited sensing schemes. This is the major unsolved problem due to the formation of capsules by the foreign body response upon implantation of a sensor. ImplantSens will not only contribute to the painless long‐term monitoring of glucose levels for diabetic patients but also to the development of future implantable sensors for the management of other chronic diseases. 11 ESR will be engaged in all tasks of this scientific chain, thus being trained in the fundamentals of bioelectrochemistry, enzyme engineering, electrode design as well as biocompatibility. Training of the fellows will be performed via an innovative program based on a blended learning concept and will take place at the host institutions, via secondments, workshops, schools and e-learning elements. The scientific training will be completed by training of complementary skill with respect to management, fund raising, IPR and scientific communication. The consortium consists of 7 leading scientists in Europe with the necessary expertise to target this ambitious goal supported by 4 SMEs. ÍmplantSens will improve the availability of a highly skilled workforce for European industries and research strongly needed for at the beginning of the 4th industrial revolution.
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MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)Coordinateur
44801 Bochum
Allemagne