European Commission logo
italiano italiano
CORDIS - Risultati della ricerca dell’UE
CORDIS

Ocular Research By Integrated Training And Learning

Risultati finali

Launch of ORBITAL website and social media

ORBITALs website and social media presence will be launched at an early a stage as possible to ensure awareness as well as a platform for engagement with the scientific and lay communities

Pubblicazioni

Validation of a Rapid and Easy-to-Apply Method to Simultaneously Quantify Co-Loaded Dexamethasone and Melatonin PLGA Microspheres by HPLC-UV: Encapsulation Efficiency and In Vitro Release

Autori: Marco Brugnera; Marta Vicario-de-la-Torre; Vanessa Andrés-Guerrero; Irene Bravo-Osuna; Irene Teresa Molina-Martínez; Rocío Herrero-Vanrell
Pubblicato in: Pharmaceutics; Volume 14; Numero 2; Pages: 288, Numero 5, 2022, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14020288

Phosphorylcholine-Based Contact Lenses for Sustained Release of Resveratrol: Design, Antioxidant and Antimicrobial Performances, and In Vivo Behavior

Autori: Maria Vivero-Lopez, Ana F. Pereira-da-Mota, Gonzalo Carracedo, Fernando Huete-Toral, Ana Parga, Ana Otero, Angel Concheiro, and Carmen Alvarez-Lorenzo
Pubblicato in: ACS Appl. Mater. Interfaces, Numero 14, 2022, Pagina/e 55431–55446, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.2c18217

Oxidative Stress in the Anterior Ocular Diseases: Diagnostic and Treatment

Autori: Azza Dammak; Cristina Pastrana; Alba Martin-Gil; Carlos Carpena-Torres; Assumpta Peral Cerda; Mirjam Simovart; Pilar Alarma; Fernando Huete-Toral; Gonzalo Carracedo
Pubblicato in: instname:, Numero 4, 2023, ISSN 2227-9059
Editore: MDPI
DOI: 10.3390/biomedicines11020292

Ocular application of electrospun materials for drug delivery and cellular therapies

Autori: Deepakkumar Mishra; Shilpkala Gade; Varun Pathak; Lalitkumar K Vora; Kiran Mcloughlin; Reinhold Medina; Ryan F Donnelly; Thakur Raghu Raj Singh
Pubblicato in: Mishra , D , Gade , S , Pathak , V , Vora , L K , Mcloughlin , K , Medina , R , Donnelly , R F & Raghu Raj Singh , T 2023 , ' Ocular application of electrospun materials for drug delivery and cellular therapies ' , Drug Discovery Today , vol. 28 , no. 9 , 103676 . https://doi.org/10.1016/j.drudis.2023.103676, Numero 1, 2023, ISSN 1359-6446
Editore: Elsevier BV
DOI: 10.1016/j.drudis.2023.103676

Melatonin-Eluting Contact Lenses Effect on Tear Volume: In Vitro and In Vivo Experiments

Autori: María Serramito, Ana F. Pereira-da-Mota, Carlos Carpena-Torres, Fernando Huete-Toral, Carmen Alvarez-Lorenzo, and Gonzalo Carracedo
Pubblicato in: Pharmaceutics, Numero 1019, 2022, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14051019

Epidemiologie okulärer Manifestationen bei Autoimmunkrankheiten

Autori: Katie Glover; Deepakkumar Mishra; Thakur Raghu Raj Singh
Pubblicato in: Kompass Ophthalmologie, Numero Volume 8, Numero 1, 2022, Pagina/e 2-17, ISSN 2297-0118
Editore: KARGER
DOI: 10.1159/000521961

Ocular Disorders and Associated Drug Development Challenges: The Current Scenario

Autori: Mishra, Deepakkumar; Gade, Shilpkala; Singh, Thakur Raghu Raj
Pubblicato in: EC Ophthalmology, Numero 11.6, 2020, Pagina/e 92-101, ISSN 2453-188X
Editore: Queens University Belfast

Diabetic eye: associated diseases, drugs in clinic, and role of self-assembled carriers in topical treatment

Autori: Axel Kattar, Angel Concheiro, Carmen Alvarez-Lorenzo
Pubblicato in: Expert Opinion on Drug Delivery, 2021, Pagina/e 1-19, ISSN 1742-5247
Editore: Ashley Publications Ltd.
DOI: 10.1080/17425247.2021.1953466

How patient/public involvement impacts the research journey – an overview of the visual impairment research field

Autori: Tess Ames; Evan Matthews; Alison Reynolds; Laurence Fitzhenry; Ann Logan; Martina Gooney; Helena Prior Filipe
Pubblicato in: Open Research Europe, Numero 2, 2023, ISSN 2732-5121
Editore: Open Research Europe
DOI: 10.12688/openreseurope.16057.1

In vitro–in vivo correlation of drug release profiles from medicated contact lenses using an in vitro eye blink model.

Autori: Ana F. Pereira-da-Mota, Maria Vivero-Lopez, Piyush Garg, Chau-Minh Phan, Angel Concheiro, Lyndon Jones & Carmen Alvarez-Lorenzo
Pubblicato in: Drug Delivery and Translational Research, Numero 13, 2023, Pagina/e 1116–1127, ISSN 2190-3948
Editore: Springer Nature
DOI: 10.1007/s13346-022-01276-6

Testing drug release from medicated contact lenses: the missing link to predict in vivo performance

Autori: Ana F. Pereira-da-Mota, Chau-Minh Phan, Angel Concheiro, Lyndon Jones, Carmen Alvarez-Lorenzo
Pubblicato in: Journal of Controlled Release, Numero 343, 2022, Pagina/e 672-702, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2022.02.014

New Biomarker Combination Related to Oxidative Stress and Inflammation in Primary Open-Angle Glaucoma

Autori: Azza Dammak; Juan Sanchez Naves; Fernando Huete-Toral; Gonzalo Carracedo
Pubblicato in: Life; Volume 13; Numero 7; Pages: 1455, Numero 2, 2023, Pagina/e 13/7:1455, ISSN 2075-1729
Editore: MDPI
DOI: 10.3390/life13071455

Atorvastatin-Eluting Contact Lenses: Effects of Molecular Imprinting and Sterilization on Drug Loading and Release

Autori: Ana F. Pereira-da-Mota, María Vivero-Lopez, Ana Topete, Ana Paula Serro, Angel Concheiro, Carmen Alvarez-Lorenzo
Pubblicato in: Pharmaceutics, Numero 13/5, 2021, Pagina/e 606, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13050606

Novel electrospun implants of Sunitinib can depress ex-vivo ocular neovascularization

Autori: Deepakkumar Mishra; Hákon Hrafn Sigurðsson; Ana Paula Serro; Giedrius Kalesnykas; Ryan F Donnelly; Raghu Raj Singh Thakur
Pubblicato in: Mishra , D , Sigurðsson , H H , Serro , A P , Kalesnykas , G , Donnelly , R & Singh , T R R 2022 , ' Novel electrospun implants of Sunitinib can depress ex-vivo ocular neovascularization ' , British Journal of Pharmacy , vol. 7 , no. 2 . https://doi.org/10.5920/bjpharm.1174, Numero 1, 2022, ISSN 2058-8356
Editore: British Journal of Pharmacy
DOI: 10.5920/bjpharm.1174

Nanostructured Lipid Carriers for Enhanced Transscleral Delivery of Dexamethasone Acetate: Development, Ex Vivo Characterization and Multiphoton Microscopy Studies

Autori: González-Fernández, Felipe M; Delledonne, Andrea; Nicoli, Sara; Gasco, Paolo; Padula, Cristina; Santi, Patrizia; Sissa, Cristina; Pescina, Silvia
Pubblicato in: Pharmaceutics, Volume 15, Numero 2 (February 2023), Numero 3, 2023, Pagina/e 407, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15020407

Niosomes-based gene delivery systems for effective transfection of human mesenchymal stem cells

Autori: Natalia Carballo-Pedrares, Axel Kattar, Angel Concheiro, Carmen Alvarez-Lorenzo, Ana Rey-Rico
Pubblicato in: Materials Science and Engineering: C, Numero 128, 2021, Pagina/e 112307, ISSN 0928-4931
Editore: Elsevier BV
DOI: 10.1016/j.msec.2021.112307

Injectable depot forming thermoresponsive hydrogel for sustained intrascleral delivery of sunitinib using hollow microneedles

Autori: Gade, Shilpkala Shankar; Pentlavalli, Sreekanth; Mishra, Deepakkumar; Vora, Lalitkumar K.; Waite, David; Alvarez-Lorenzo, Carmen Isabel; Herrero Vanrell, Maria Roccio; Laverty, Garry; Larrañeta, Eneko; Donnelly, Ryan F.; Singh Thakur, Raghu Raj
Pubblicato in: ournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, Numero 38(6), 2022, Pagina/e 433-448, ISSN 1557-7732
Editore: Mary Ann Liebert, Inc
DOI: 10.1089/jop.2022.0016

From Oxidative Stress to Inflammation in the Posterior Ocular Diseases: Diagnosis and Treatment.

Autori: Azza Dammak; Fernando Huete-Toral; Carlos Carpena-Torres; Alba Martin-Gil; Cristina Pastrana; Gonzalo Carracedo
Pubblicato in: Pharmaceutics, Numero 13, 2021, Pagina/e 1376, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13091376

Therapeutic Ophthalmic Lenses: A Review

Autori: Nadia Toffoletto, Benilde Saramago, Ana Paula Serro
Pubblicato in: Pharmaceutics, Numero 13/1, 2021, Pagina/e 36, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13010036

Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications

Autori: Patrizia Colucci; Martina Giannaccini; Matteo Baggiani; Breandán N. Kennedy; Luciana Dente; Vittoria Raffa; Chiara Gabellini
Pubblicato in: Pharmaceutics; Volume 15; Numero 4; Pages: 1096, Numero 2, 2023, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15041096

Development and characterization of injectable depot forming thermoresponsive hydrogel for the sustained intrascleral delivery of Sunitinib

Autori: Shilpkala Gade; Eneko Larrañeta; Ryan F Donnelly; Rocio Herrero Vanrell; Carmen Isabel Alvarez Lorenzo; Raghu Raj Singh Thakur
Pubblicato in: British Journal of Pharmacy, Numero Volume 7, Numero 2, 2022, ISSN 2058-8356
Editore: University of Huddersfield Press
DOI: 10.5920/bjpharm.1175

A physiology-based mathematical model to understand drug delivery from contact lenses to the back of the eye

Autori: N. Toffoletto, B. Saramago, A.P. Serro, A. Chauhan
Pubblicato in: Pharmaceutical Research, 2023, Pagina/e 40(8) 1939–1951, ISSN 0724-8741
Editore: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11095-023-03560-7

Dexamethasone phosphate and penetratin co-eluting contact lenses: a strategy to enhance ocular drug permeability

Autori: N. Toffoletto, M. Salema-Oom, S. Nicoli, S. Pescina, F.M. González-Fernández C.A. Pinto, J.A. Saraiva, A.P.A. Matos, M. Vivero-Lopez; F. Huete-Toral, G. Carracedo, B. Saramago, A.P. Serro
Pubblicato in: International Journal of Pharmaceutics, 2024, Pagina/e 650 (2024)123685, ISSN 0378-5173
Editore: Elsevier BV
DOI: 10.1016/j.ijpharm.2023.123685

Formulation and Characterization of Epalrestat-Loaded Polysorbate 60 Cationic Niosomes for Ocular Delivery

Autori: Axel Kattar; Ana Quelle-Regaldie; Laura Sánchez; Angel Concheiro; Carmen Alvarez-Lorenzo
Pubblicato in: reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela, Numero 1, 2023, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15041247

Penetration Enhancers for Topical Drug Delivery to the Ocular Posterior Segment—A Systematic Review

Autori: Abhinav Thareja, Helen Hughes, Carmen Alvarez-Lorenzo, Jenni J. Hakkarainen, Zubair Ahmed
Pubblicato in: Pharmaceutics, Numero 13/2, 2021, Pagina/e 276, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13020276

Mucoadhesive gellan gum-based and carboxymethyl cellulose -based hydrogels containing gemcitabine and papain for bladder cancer treatment

Autori: Caroline S.A. de Lima; M. Isabel Rial-Hermida; Lucas Freitas de Freitas; Ana F. Pereira-da-Mota; Maria Vivero-Lopez; Aryel Heitor Ferreira; Sławomir Kadłubowski; Gustavo H.C. Varca; Ademar B. Lugão; Carmen Alvarez-Lorenzo
Pubblicato in: Crossref, Numero 2, 2023, ISSN 0141-8130
Editore: Elsevier BV
DOI: 10.1016/j.ijbiomac.2023.124957

Contact lenses for pravastatin delivery to eye segments: Design and in vitro-in vivo correlations

Autori: Ana F.Pereira-da-Mota, Maria Vivero-Lopez, Maria Serramito, Luis Diaz-Gomez, Ana Paula Serro, Gonzalo Carracedo, Fernando Huete-Toral, Angel Concheiro, Carmen Alvarez-Lorenzo
Pubblicato in: Journal of Controlled Release, Numero 348, 2022, Pagina/e 431-443, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2022.06.001

Asymmetry in Drug Permeability through the Cornea

Autori: Nadia Toffoletto, Anuj Chauhan, Carmen Alvarez-Lorenzo, Benilde Saramago, Ana Paula Serro
Pubblicato in: Pharmaceutics, Numero 13/5, 2021, Pagina/e 694, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13050694

Posterior Segment Ophthalmic Drug Delivery: Role of Muco-Adhesion with a Special Focus on Chitosan

Autori: Ayah Mohammad Burhan; Butsabarat Klahan; Wayne Cummins; Vanessa Andrés-Guerrero; Mark E. Byrne; Niall J. O’Reilly; Anuj Chauhan; Laurence Fitzhenry; Helen Hughes
Pubblicato in: Pharmaceutics, Numero 13, 2021, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13101685

Epidemiology of Ocular Manifestations in Autoimmune Disease

Autori: Katie Glover; Deepakkumar Mishra; Thakur Raghu Raj Singh
Pubblicato in: Frontiers in Immunology, Numero 2, 2021, ISSN 1664-3224
Editore: Frontiers
DOI: 10.3389/fimmu.2021.744396

Penetration enhancers for topical drug delivery to the ocular posterior segment: a systematic Review

Autori: Thareja, Abhinav; Hughes, Helen; Álvarez Lorenzo, Carmen Isabel; Hakkarainen, Jenni J.; Ahmed, Zubair
Pubblicato in: reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela, Numero 1, 2021, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13020276

Drug-Loaded Hydrogels for Intraocular Lenses with Prophylactic Action against Pseudophakic Cystoid Macular Edema

Autori: Nadia Toffoletto, Madalena Salema-Oom, Soledad Anguiano Igea, Carmen Alvarez-Lorenzo, Benilde Saramago, Ana Paula Serro
Pubblicato in: Pharmaceutics, Numero 13/7, 2021, Pagina/e 976, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13070976

Langmuir monolayer studies of non-ionic surfactants and DOTMA for the design of ophthalmic niosomes

Autori: Axel Kattar Emílio V. Lage Matilde Casas Angel Concheiro Carmen Alvarez-Lorenzo
Pubblicato in: Heliyon, 2024, ISSN 2405-8440
Editore: Elsevier
DOI: 10.1016/j.heliyon.2024.e25887

Lipid-Based Nanocarriers for Ophthalmic Administration: Towards Experimental Design Implementation

Autori: Felipe M. González-Fernández, Annalisa Bianchera, Paolo Gasco, Sara Nicoli, Silvia Pescina
Pubblicato in: Pharmaceutics, Numero 13/4, 2021, Pagina/e 447, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13040447

Development of 3D-printed devices for the study of transscleral drug delivery on freshly excised whole porcine eyes

Autori: Felipe M. González-Fernández, Daniele A. Cauzzi, Sara Nicoli, Paolo Gasco, Silvia Pescina
Pubblicato in: Volume 100, Numero S275 Special Numero:Abstracts from the 2022 European Association for Vision and Eye Research Festival, 13‐15 October 2022, Valencia, 2022
Editore: Wiley
DOI: 10.1111/j.1755-3768.2022.15545

È in corso la ricerca di dati su OpenAIRE...

Si è verificato un errore durante la ricerca dei dati su OpenAIRE

Nessun risultato disponibile