EVPRO - Development of Extracellular Vesicles loaded hydrogel coatings with immunomodulatory activity for Promoted Regenerative Osseointegration of revision endoprosthesis

Información del proyecto

EVPRO

Identificador del acuerdo de subvención: 814495

DOI

10.3030/814495

Proyecto cerrado

Fecha de la firma de la CE 14 Diciembre 2018

Fecha de inicio 1 Enero 2019

Fecha de finalización 30 Noviembre 2023

Financiado con arreglo a

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials

Coste total

€ 5 799 088,75

Aportación de la UE

€ 5 799 088,75

Coordinado por

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (2)

Summary Report on Dissemination and Communication Activities

With their active participation in the dissemination and the exploitation activities, all partners contribute to an effective and time sustainable deployment of project results. Dissemination of the project results is performed in parallel with exploitation, maximising the potential benefits of public awareness.

Dissemination and Communication Plan

This is targets a broad audience and the highest possible impact. For this reason, the dissemination of the developed concept includes newsletters, papers on scientific and technical journals and conferences and the creation and management of a website and the respective forum in social media.

Websites, patent fillings, videos etc. (1)

Project website, Twitter, Facebook

Coordinate the dissemination of project results to targeted audiences with the use of adequate sets of mediaThe purpose of the website is to make project developments visible in a timely manner; the forum will be used for discussions to get direct feedback of external stakeholders

Publicaciones

Peer reviewed articles (8)

Nanovesicles displaying functional linear and branched oligomannose self-assembled from sequence-defined Janus glycodendrimers

Autores: Qi Xiao, Martina Delbianco, Samuel E. Sherman, Aracelee M. Reveron Perez, Priya Bharate, Alonso Pardo-Vargas, Cesar Rodriguez-Emmenegger, Nina Yu Kostina, Khosrow Rahimi, Dominik Söder, Martin Möller, Michael L. Klein, Peter H. Seeberger, Virgil Percec
Publicado en: Proceedings of the National Academy of Sciences, Edición 117/22, 2020, Página(s) 11931-11939, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2003938117

Mesenchymal Stem Cell Derived Extracellular Vesicles for Tissue Engineering and Regenerative Medicine Applications

Autores: Dimitrios Tsiapalis, Lorraine O’Driscoll
Publicado en: Cells, Edición 9/4, 2020, Página(s) 991, ISSN 2073-4409
Editor: MDPI AG
DOI: 10.3390/cells9040991

Unraveling topology-induced shape transformations in dendrimersomes

Autores: Nina Yu. Kostina, Anna M. Wagner, Tamás Haraszti, Khosrow Rahimi, Qi Xiao, Michael L. Klein, Virgil Percec, Cesar Rodriguez-Emmenegger
Publicado en: Soft Matter, 2020, ISSN 1744-683X
Editor: Royal Society of Chemistry
DOI: 10.1039/d0sm01097a

Photoinduced Upgrading of Lactic Acid-Based Solvents to Block Copolymer Surfactants

Autores: Nabil Bensabeh, Adrian Moreno, Adrià Roig, Mehrnoush Rahimzadeh, Khosrow Rahimi, Juan Carlos Ronda, Virginia Cádiz, Marina Galià, Virgil Percec, Cesar Rodriguez-Emmenegger, Gerard Lligadas
Publicado en: ACS Sustainable Chemistry & Engineering, Edición 8/2, 2019, Página(s) 1276-1284, ISSN 2168-0485
Editor: American Chemical Society
DOI: 10.1021/acssuschemeng.9b06599

Direct Visualization of Vesicle Disassembly and Reassembly Using Photocleavable Dendrimers Elucidates Cargo Release Mechanisms

Autores: Shangda Li, Boao Xia, Bilal Javed, William D. Hasley, Adriel Melendez-Davila, Matthew Liu, Meir Kerzner, Shriya Agarwal, Qi Xiao, Paola Torre, Jessica G. Bermudez, Khosrow Rahimi, Nina Yu. Kostina, Martin Möller, Cesar Rodriguez-Emmenegger, Michael L. Klein, Virgil Percec, Matthew C. Good
Publicado en: ACS Nano, Edición 14/6, 2020, Página(s) 7398-7411, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.0c02912

In vitro biocompatibility analysis of protein-resistant amphiphilic polysulfobetaines as coatings for surgical implants in contact with complex body fluids

Autores: Jana F. Karthäuser, Dierk Gruhn, Alejandro Martínez Guajardo, Regina Kopecz, Nina Babel, Ulrik Stervbo, André Laschewsky, Richard Viebahn, Jochen Salber, Axel Rosenhahn
Publicado en: Frontiers in Bioengineering and Biotechnology, Edición 12, 2024, ISSN 2296-4185
Editor: Frontiers Media SA
DOI: 10.3389/fbioe.2024.1403654

Doxorubicin Loading into Milk and Mesenchymal Stem Cells’ Extracellular Vesicles as Drug Delivery Vehicles

Autores: Anindya Mukhopadhya, Dimitrios Tsiapalis, Niamh McNamee, Brian Talbot, Lorraine O’Driscoll
Publicado en: Pharmaceutics, Edición 15, 2023, Página(s) 718, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15030718

Encapsulation of hydrophobic components in dendrimersomes and decoration of their surface with proteins and nucleic acids

Autores: Paola Torre, Qi Xiao, Irene Buzzacchera, Samuel E. Sherman, Khosrow Rahimi, Nina Yu. Kostina, Cesar Rodriguez-Emmenegger, Martin Möller, Christopher J. Wilson, Michael L. Klein, Matthew C. Good, Virgil Percec
Publicado en: Proceedings of the National Academy of Sciences, Edición 116/31, 2019, Página(s) 15378-15385, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.1904868116