EVPRO - Development of Extracellular Vesicles loaded hydrogel coatings with immunomodulatory activity for Promoted Regenerative Osseointegration of revision endoprosthesis

Informacje na temat projektu

EVPRO

Identyfikator umowy o grant: 814495

DOI

10.3030/814495

Projekt został zamknięty

Data podpisania przez KE 14 Grudnia 2018

Data rozpoczęcia 1 Stycznia 2019

Data zakończenia 30 Listopada 2023

Finansowanie w ramach

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials

Koszt całkowity

€ 5 799 088,75

Wkład UE

€ 5 799 088,75

Koordynowany przez

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (2)

Summary Report on Dissemination and Communication Activities

With their active participation in the dissemination and the exploitation activities, all partners contribute to an effective and time sustainable deployment of project results. Dissemination of the project results is performed in parallel with exploitation, maximising the potential benefits of public awareness.

Dissemination and Communication Plan

This is targets a broad audience and the highest possible impact. For this reason, the dissemination of the developed concept includes newsletters, papers on scientific and technical journals and conferences and the creation and management of a website and the respective forum in social media.

Websites, patent fillings, videos etc. (1)

Project website, Twitter, Facebook

Coordinate the dissemination of project results to targeted audiences with the use of adequate sets of mediaThe purpose of the website is to make project developments visible in a timely manner; the forum will be used for discussions to get direct feedback of external stakeholders

Publikacje

Peer reviewed articles (8)

Nanovesicles displaying functional linear and branched oligomannose self-assembled from sequence-defined Janus glycodendrimers

Autorzy: Qi Xiao, Martina Delbianco, Samuel E. Sherman, Aracelee M. Reveron Perez, Priya Bharate, Alonso Pardo-Vargas, Cesar Rodriguez-Emmenegger, Nina Yu Kostina, Khosrow Rahimi, Dominik Söder, Martin Möller, Michael L. Klein, Peter H. Seeberger, Virgil Percec
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 117/22, 2020, Strona(/y) 11931-11939, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2003938117

Mesenchymal Stem Cell Derived Extracellular Vesicles for Tissue Engineering and Regenerative Medicine Applications

Autorzy: Dimitrios Tsiapalis, Lorraine O’Driscoll
Opublikowane w: Cells, Numer 9/4, 2020, Strona(/y) 991, ISSN 2073-4409
Wydawca: MDPI AG
DOI: 10.3390/cells9040991

Unraveling topology-induced shape transformations in dendrimersomes

Autorzy: Nina Yu. Kostina, Anna M. Wagner, Tamás Haraszti, Khosrow Rahimi, Qi Xiao, Michael L. Klein, Virgil Percec, Cesar Rodriguez-Emmenegger
Opublikowane w: Soft Matter, 2020, ISSN 1744-683X
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d0sm01097a

Photoinduced Upgrading of Lactic Acid-Based Solvents to Block Copolymer Surfactants

Autorzy: Nabil Bensabeh, Adrian Moreno, Adrià Roig, Mehrnoush Rahimzadeh, Khosrow Rahimi, Juan Carlos Ronda, Virginia Cádiz, Marina Galià, Virgil Percec, Cesar Rodriguez-Emmenegger, Gerard Lligadas
Opublikowane w: ACS Sustainable Chemistry & Engineering, Numer 8/2, 2019, Strona(/y) 1276-1284, ISSN 2168-0485
Wydawca: American Chemical Society
DOI: 10.1021/acssuschemeng.9b06599

Direct Visualization of Vesicle Disassembly and Reassembly Using Photocleavable Dendrimers Elucidates Cargo Release Mechanisms

Autorzy: Shangda Li, Boao Xia, Bilal Javed, William D. Hasley, Adriel Melendez-Davila, Matthew Liu, Meir Kerzner, Shriya Agarwal, Qi Xiao, Paola Torre, Jessica G. Bermudez, Khosrow Rahimi, Nina Yu. Kostina, Martin Möller, Cesar Rodriguez-Emmenegger, Michael L. Klein, Virgil Percec, Matthew C. Good
Opublikowane w: ACS Nano, Numer 14/6, 2020, Strona(/y) 7398-7411, ISSN 1936-0851
Wydawca: American Chemical Society
DOI: 10.1021/acsnano.0c02912

In vitro biocompatibility analysis of protein-resistant amphiphilic polysulfobetaines as coatings for surgical implants in contact with complex body fluids

Autorzy: Jana F. Karthäuser, Dierk Gruhn, Alejandro Martínez Guajardo, Regina Kopecz, Nina Babel, Ulrik Stervbo, André Laschewsky, Richard Viebahn, Jochen Salber, Axel Rosenhahn
Opublikowane w: Frontiers in Bioengineering and Biotechnology, Numer 12, 2024, ISSN 2296-4185
Wydawca: Frontiers Media SA
DOI: 10.3389/fbioe.2024.1403654

Doxorubicin Loading into Milk and Mesenchymal Stem Cells’ Extracellular Vesicles as Drug Delivery Vehicles

Autorzy: Anindya Mukhopadhya, Dimitrios Tsiapalis, Niamh McNamee, Brian Talbot, Lorraine O’Driscoll
Opublikowane w: Pharmaceutics, Numer 15, 2023, Strona(/y) 718, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15030718

Encapsulation of hydrophobic components in dendrimersomes and decoration of their surface with proteins and nucleic acids

Autorzy: Paola Torre, Qi Xiao, Irene Buzzacchera, Samuel E. Sherman, Khosrow Rahimi, Nina Yu. Kostina, Cesar Rodriguez-Emmenegger, Martin Möller, Christopher J. Wilson, Michael L. Klein, Matthew C. Good, Virgil Percec
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 116/31, 2019, Strona(/y) 15378-15385, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1904868116