EVPRO - Development of Extracellular Vesicles loaded hydrogel coatings with immunomodulatory activity for Promoted Regenerative Osseointegration of revision endoprosthesis

Informazioni relative al progetto

EVPRO

ID dell’accordo di sovvenzione: 814495

DOI

10.3030/814495

Progetto chiuso

Data della firma CE 14 Dicembre 2018

Data di avvio 1 Gennaio 2019

Data di completamento 30 Novembre 2023

Finanziato da

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials

Costo totale

€ 5 799 088,75

Contributo UE

€ 5 799 088,75

Coordinato da

FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG EV
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (2)

Summary Report on Dissemination and Communication Activities

With their active participation in the dissemination and the exploitation activities, all partners contribute to an effective and time sustainable deployment of project results. Dissemination of the project results is performed in parallel with exploitation, maximising the potential benefits of public awareness.

Dissemination and Communication Plan

This is targets a broad audience and the highest possible impact. For this reason, the dissemination of the developed concept includes newsletters, papers on scientific and technical journals and conferences and the creation and management of a website and the respective forum in social media.

Websites, patent fillings, videos etc. (1)

Project website, Twitter, Facebook

Coordinate the dissemination of project results to targeted audiences with the use of adequate sets of mediaThe purpose of the website is to make project developments visible in a timely manner; the forum will be used for discussions to get direct feedback of external stakeholders

Pubblicazioni

Peer reviewed articles (8)

Nanovesicles displaying functional linear and branched oligomannose self-assembled from sequence-defined Janus glycodendrimers

Autori: Qi Xiao, Martina Delbianco, Samuel E. Sherman, Aracelee M. Reveron Perez, Priya Bharate, Alonso Pardo-Vargas, Cesar Rodriguez-Emmenegger, Nina Yu Kostina, Khosrow Rahimi, Dominik Söder, Martin Möller, Michael L. Klein, Peter H. Seeberger, Virgil Percec
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 117/22, 2020, Pagina/e 11931-11939, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2003938117

Mesenchymal Stem Cell Derived Extracellular Vesicles for Tissue Engineering and Regenerative Medicine Applications

Autori: Dimitrios Tsiapalis, Lorraine O’Driscoll
Pubblicato in: Cells, Numero 9/4, 2020, Pagina/e 991, ISSN 2073-4409
Editore: MDPI AG
DOI: 10.3390/cells9040991

Unraveling topology-induced shape transformations in dendrimersomes

Autori: Nina Yu. Kostina, Anna M. Wagner, Tamás Haraszti, Khosrow Rahimi, Qi Xiao, Michael L. Klein, Virgil Percec, Cesar Rodriguez-Emmenegger
Pubblicato in: Soft Matter, 2020, ISSN 1744-683X
Editore: Royal Society of Chemistry
DOI: 10.1039/d0sm01097a

Photoinduced Upgrading of Lactic Acid-Based Solvents to Block Copolymer Surfactants

Autori: Nabil Bensabeh, Adrian Moreno, Adrià Roig, Mehrnoush Rahimzadeh, Khosrow Rahimi, Juan Carlos Ronda, Virginia Cádiz, Marina Galià, Virgil Percec, Cesar Rodriguez-Emmenegger, Gerard Lligadas
Pubblicato in: ACS Sustainable Chemistry & Engineering, Numero 8/2, 2019, Pagina/e 1276-1284, ISSN 2168-0485
Editore: American Chemical Society
DOI: 10.1021/acssuschemeng.9b06599

Direct Visualization of Vesicle Disassembly and Reassembly Using Photocleavable Dendrimers Elucidates Cargo Release Mechanisms

Autori: Shangda Li, Boao Xia, Bilal Javed, William D. Hasley, Adriel Melendez-Davila, Matthew Liu, Meir Kerzner, Shriya Agarwal, Qi Xiao, Paola Torre, Jessica G. Bermudez, Khosrow Rahimi, Nina Yu. Kostina, Martin Möller, Cesar Rodriguez-Emmenegger, Michael L. Klein, Virgil Percec, Matthew C. Good
Pubblicato in: ACS Nano, Numero 14/6, 2020, Pagina/e 7398-7411, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.0c02912

In vitro biocompatibility analysis of protein-resistant amphiphilic polysulfobetaines as coatings for surgical implants in contact with complex body fluids

Autori: Jana F. Karthäuser, Dierk Gruhn, Alejandro Martínez Guajardo, Regina Kopecz, Nina Babel, Ulrik Stervbo, André Laschewsky, Richard Viebahn, Jochen Salber, Axel Rosenhahn
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 12, 2024, ISSN 2296-4185
Editore: Frontiers Media SA
DOI: 10.3389/fbioe.2024.1403654

Doxorubicin Loading into Milk and Mesenchymal Stem Cells’ Extracellular Vesicles as Drug Delivery Vehicles

Autori: Anindya Mukhopadhya, Dimitrios Tsiapalis, Niamh McNamee, Brian Talbot, Lorraine O’Driscoll
Pubblicato in: Pharmaceutics, Numero 15, 2023, Pagina/e 718, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15030718

Encapsulation of hydrophobic components in dendrimersomes and decoration of their surface with proteins and nucleic acids

Autori: Paola Torre, Qi Xiao, Irene Buzzacchera, Samuel E. Sherman, Khosrow Rahimi, Nina Yu. Kostina, Cesar Rodriguez-Emmenegger, Martin Möller, Christopher J. Wilson, Michael L. Klein, Matthew C. Good, Virgil Percec
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 116/31, 2019, Pagina/e 15378-15385, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1904868116