Deliverables Websites, patent fillings, videos etc. (9) Periodic newsletters (M12) Periodic newsletters Candidate gene lists Candidate gene lists Validated growth-coupled methyl-transferase system for 1 MIA compound Validated growth-coupled methyl-transferase system for 1 MIA compound Periodic newsletters (M24) Periodic newsletters Expression atlas Expression atlas Annotated reference genome of Rauvolfia tetraphylla Annotated reference genome of Rauvolfia tetraphylla Project website: the report will provide a functional description of the project website and its main sections. Project website: the report will provide a functional description of the project website and its main sections. Press release about the launching of MIAMi project will be sent to the media to disseminate the project Press release about the launching of MIAMi project will be sent to the media to disseminate the project "Final version of the ""Plan for the Use and Dissemination of the Foreground"" (PUDF)" Final version of the Plan for the Use and Dissemination of the Foreground PUDF Documents, reports (4) Establish localization patterns of alkaloids in Rauvolfia sp. Establish localization patterns of alkaloids in Rauvolfia sp List of identified metabolites (and corresponding accurate masses) in Rauvolfia serpentina and Rauvolfia tetraphylla plants List of identified metabolites (and corresponding accurate masses) in Rauvolfia serpentina and Rauvolfia tetraphylla plants Publicly available SOPs Publicly available SOPs Sample preparation methods for MSI studies of various parts of the Rauvolfia serpentina and Rauvolfia tetraphylla plants Sample preparation methods for MSI studies of various parts of the Rauvolfia serpentina and Rauvolfia tetraphylla plants Open Research Data Pilot (1) First version of data management plan as required by Open Research Data Pilot First version of data management plan as required by Open Research Data Pilot Publications Peer reviewed articles (20) Peroxisomes: A New Hub for Metabolic Engineering in Yeast Author(s): Natalja Kulagina, Sébastien Besseau, Nicolas Papon and Vincent Courdavault Published in: Frontiers in Bioengineering and Biotechnology, 2021, ISSN 2296-4185 Publisher: Frontiers in Bioengineering and Biotechnology DOI: 10.3389/fbioe.2021.659431 Tracking the Origin and Evolution of Plant Metabolites Author(s): Christophe Duplais, Nicolas Papon, Vincent Courdavault Published in: Trends in plant science, 2020, Page(s) 1182-1184, ISSN 1878-4372 Publisher: Trends in plant science DOI: 10.1016/j.tplants.2020.08.010 Deploying Microbial Synthesis for Halogenating and Diversifying Medicinal Alkaloid Scaffolds Author(s): Samuel Alan Bradley; Jie Zhang; Michael Krogh Jensen Published in: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020), 2, 2020, ISSN 2296-4185 Publisher: Frontiers in Bioengineering and Biotechnology DOI: 10.3389/fbioe.2020.594126 A FAIR-compliant parts catalogue for genome engineering and expression control in Saccharomyces cerevisiae Author(s): Vasil D'Ambrosio, Lea G Hansen, Jie Zhang, Emil D Jensen, Dushica Arsovska, Marcos Laloux, Tadas Jakočiūnas, Pernille Hjort, Davide De Lucrezia , Serena Marletta, Jay D Keasling and Michael K Jensen Published in: Synth Syst Biotechnol ., 16;7(2), 2022, Page(s) 657-663, ISSN 2405-805X Publisher: KeAi Publishing Communications Ltd. DOI: 10.1016/j.synbio.2022.02.001 Improved virus-induced gene silencing allows discovery of a serpentine synthase gene in Catharanthus roseus Author(s): Kotaro Yamamoto; Dagny Grzech; Konstantinos Koudounas; Emily Amor Stander; Lorenzo Caputi; Tetsuro Mimura; Vincent Courdavault; Sarah E. O’Connor Published in: Plant Physiology, 5, 2021, ISSN 0032-0889 Publisher: American Society of Plant Biologists DOI: 10.1093/plphys/kiab285 Computational biotechnology guides elucidation of the biosynthesis of the plant anticancer drug camptothecin Author(s): Emily Amor Stander, ThomasDugé de Bernonville, Nicolas Papon, Vincent Courdavault Published in: Computational and Structural Biotechnology Journal, 2021, ISSN 2001-0370 Publisher: Computational and Structural Biotechnology Journal DOI: 10.1016/j.csbj.2021.06.028 Metabolic engineering for plant natural products biosynthesis: new procedures, concrete achievements and remaining limits Author(s): Nicolas Papon; Vincent Courdavault; Sarah O'Connor; Michael Krogh Jensen Published in: Natural Product Reports, 38(12), 5, 2021, Page(s) 2145-2153, ISSN 0265-0568 Publisher: Royal Society of Chemistry DOI: 10.1039/d0np00092b Enhanced bioproduction of anticancer precursor vindoline by yeast cell factories Author(s): Natalja Kulagina, Grégory Guirimand, Céline Melin, Pamela Lemos-Cruz, Ines Carqueijeiro, Johan-Owen De Craene, Audrey Oudin, Vladimir Heredia, Konstantinos Koudounas, Marianne Unlubayir, Arnaud Lanoue, Nadine Imbault, Benoit St-Pierre, Nicolas Papon, Marc Clastre, Nathalie Giglioli-Guivarc’h, Jillian Marc, Sébastien Besseau, Vincent Courdavault Published in: Microbial Biotechnology, 2021, Page(s) 2693-2699, ISSN 1751-7915 Publisher: Microbial Biotechnology DOI: 10.1111/1751-7915.13898 Supplying plant natural products by yeast cell factories Author(s): David Romero-Suarez, Jay D.Keasling and Michael K.Jensen1 Published in: Current Opinion in Green and Sustainable Chemistry, 2022, ISSN 2452-2236 Publisher: Elsevier BV DOI: 10.1016/j.cogsc.2021.100567 Efficient Terpene Production by Marine Thraustochytrids: Shedding Light on the Thermodynamic Driving Force Author(s): Natalja Kulagina, Jennifer Perrin, Sébastien Besseau, Vincent Courdavault Published in: mBio, 2021, ISSN 2150-7511 Publisher: mBio DOI: 10.1128/mbio.01976-21 Identifying Missing Biosynthesis Enzymes of Plant Natural Products Author(s): Thomas Dugé de Bernonville, Nicolas Papon, Marc Clastre, Sarah E. O’Connor, Vincent Courdavault Published in: Trends in Pharmacological Sciences, 2020, ISSN 0165-6147 Publisher: Elsevier BV DOI: 10.1016/j.tips.2019.12.006 Evolution-guided engineering of small-molecule biosensors Author(s): Tim Snoek, Evan K Chaberski, Francesca Ambri, Stefan Kol, Sara P Bjørn, Bo Pang, Jesus F Barajas, Ditte H Welner, Michael K Jensen, Jay D Keasling Published in: Nucleic Acids Research, 48/1, 2019, Page(s) e3-e3, ISSN 0305-1048 Publisher: Oxford University Press DOI: 10.1093/nar/gkz954 Beyond the semi-synthetic artemisinin: metabolic engineering of plant-derived anti-cancer drugs Author(s): Ines Carqueijeiro, Chloe Langley, Dagny Grzech, Konstantinos Koudounas, Nicolas Papon, Sarah E O’Connor, Vincent Courdavault Published in: Current Opinion in Biotechnology, 65, 2020, Page(s) 17-24, ISSN 0958-1669 Publisher: Elsevier BV DOI: 10.1016/j.copbio.2019.11.017 Towards the Microbial Production of Plant-Derived Anticancer Drugs Author(s): Vincent Courdavault, Sarah E. O’Connor, Audrey Oudin, Sébastien Besseau, Nicolas Papon Published in: Trends in Cancer, 6/6, 2020, Page(s) 444-448, ISSN 2405-8033 Publisher: Elsevier DOI: 10.1016/j.trecan.2020.02.004 Virus-Induced Gene Silencing: Hush Genes to Make Them Talk Author(s): Vincent Courdavault, Sébastien Besseau, Audrey Oudin, Nicolas Papon, Sarah Ellen O’Connor Published in: Trends in Plant Science, 25/7, 2020, Page(s) 714-715, ISSN 1360-1385 Publisher: Elsevier BV DOI: 10.1016/j.tplants.2020.02.013 Engineering G protein-coupled receptor signalling in yeast for biotechnological and medical purposes Author(s): Bettina Lengger, Michael K Jensen Published in: FEMS Yeast Research, 20/1, 2020, ISSN 1567-1356 Publisher: Blackwell DOI: 10.1093/femsyr/foz087 Identifying Genes Involved in alkaloid Biosynthesis in Vinca minor Through Transcriptomics and Gene Co-Expression Analysis Author(s): Emily A. Stander; Liuda Johana Sepúlveda; Thomas Dugé de Bernonville; Inês Carqueijeiro; Konstantinos Koudounas; Pamela Lemos Cruz; Sébastien Besseau; Arnaud Lanoue; Nicolas Papon; Nathalie Giglioli-Guivarc’h; Ron Dirks; Sarah E. O'Connor; Lucía Atehortúa; Audrey Oudin; Vincent Courdavault Published in: Biomolecules, 1, 2020, ISSN 2218-273X Publisher: MDPI DOI: 10.3390/biom10121595 Early and Late Steps of Quinine Biosynthesis Author(s): Francesco Trenti; Kotaro Yamamoto; Benke Hong; Christian Paetz; Yoko Nakamura; Sarah E. O’Connor Published in: Organic Letters 23 (5), 5, 2021, Page(s) 1793 - 1797, ISSN 1523-7060 Publisher: American Chemical Society DOI: 10.1021/acs.orglett.1c00206 Yeasts as Biopharmaceutical Production Platforms Author(s): Natalja Kulagina, Sébastien Besseau, Charlotte Godon, Gustavo H. Goldman, Nicolas Papon and Vincent Courdavault Published in: Frontiers in fungal biotechnology, 2021, ISSN 2054-3085 Publisher: Frontiers in fungal biotechnology DOI: 10.3389/ffunb.2021.733492 Dietary Change Enables Robust Growth-Coupling of Heterologous Methyltransferase Activity in Yeast Author(s): Anne Sofie Lærke Hansen, Maitreya J. Dunham, Dushica Arsovska, Jie Zhang, Jay D. Keasling, Markus J. Herrgard, and Michael K. Jensen* Published in: ACS Synthetic Biology, 2020, Page(s) 3408–3415, ISSN 2161-5063 Publisher: American Chemical Society DOI: 10.1021/acssynbio.0c00348 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
