Navigating the evolutionary routes of influenza viruses

Project Information

NaviFlu

Grant agreement ID: 818353

DOI

10.3030/818353

Project closed

EC signature date 19 June 2019

Start date 1 July 2019

End date 30 June 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 331,00

EU contribution

€ 1 999 331,00

Coordinated by

STICHTING AMSTERDAM UMC
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Strategies for Using Antigen Rapid Diagnostic Tests to Reduce Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in Low- and Middle-Income Countries: A Mathematical Modelling Study Applied to Zambia

Author(s): Alvin X Han, Sarah J Girdwood, Shaukat Khan, Jilian A Sacks, Amy Toporowski, Naushin Huq, Emma Hannay, Colin A Russell, Brooke E Nichols
Published in: Clinical Infectious Diseases, 2023, ISSN 1058-4838
Publisher: University of Chicago Press
DOI: 10.1093/cid/ciac814

Estimating the potential impact and diagnostic requirements for SARS-CoV-2 test-and-treat programs

Author(s): Alvin X. Han; Emma Hannay; Sergio Carmona; Bill Rodriguez; Brooke E. Nichols; Colin A. Russell
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/2022.10.05.22280727

Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation

Author(s): Simon P. J. de Jong, Zandra C. Felix Garza, Joseph C. Gibson, Sarah van Leeuwen, Robert P. de Vries, Geert-Jan Boons, Marliek van Hoesel, Karen de Haan, Laura E. van Groeningen, Katina D. Hulme, Hugo D. G. van Willigen, Elke Wynberg, Godelieve J. de Bree, Amy Matser, Margreet Bakker, Lia van der Hoek, Maria Prins, Neeltje A. Kootstra, Dirk Eggink, Brooke E. Nichols, Alvin X. Han, Menno D. de Jong,
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-44668-z

Regional importation and asymmetric within-country spread of SARS-CoV-2 variants of concern in the Netherlands

Author(s): Alvin X Han; Eva Kozanli; Jelle Koopsen; Harry Vennema; Karim Hajji; Annelies Kroneman; Ivo van Walle; Don Klinkenberg; Jacco Wallinga; Colin A Russell; Dirk Eggink; Chantal Reusken
Published in: elife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.1101/2022.03.21.22272611

A single mRNA vaccine dose in COVID-19 patients boosts neutralizing antibodies against SARS-CoV-2 and variants of concern

Author(s): Marit J. van Gils, Hugo D.G. van Willigen, Elke Wynberg, Alvin X. Han, Karlijn van der Straten, Judith A. Burger, Meliawati Poniman, Melissa Oomen, Khadija Tejjani, Joey H. Bouhuijs, Anouk Verveen, Romy Lebbink, Maartje Dijkstra, Brent Appelman, A.H. Ayesha Lavell, Tom G. Caniels, Ilja Bontjer, Lonneke A. van Vught, Alexander P.J. Vlaar, Jonne J. Sikkens, Marije K. Bomers, Colin A. Russell, Neeltj
Published in: Cell Reports Medicine, Issue 3, 2023, Page(s) 100486, ISSN 2666-3791
Publisher: Elsevier BV
DOI: 10.1016/j.xcrm.2021.100486

Competition between transmission lineages mediated by human mobility shapes seasonal influenza epidemics in the US

Author(s): Simon P. J. de Jong, Andrew J. K. Conlan, Alvin X. Han, Colin A. Russell
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-59757-4

Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

Author(s): Alvin X. Han; Zandra C. Felix Garza; Matthijs R.A. Welkers; René M Vigeveno; Tran Nhu Duong; Le Thi Quynh Mai; Pham Quang Thai; Dang Dinh Thoang; Tran Thi Ngoc Anh; Ha Manh Tuan; Nguyen Thanh Hung; Le Quoc Thinh; Le Thanh Hai; Hoang Thi Bich Ngoc; Kulkanya Chokephaibulkit; Pilaipan Puthavathana; Nguyen Van Vinh Chau; Nghiem My Ngoc; Nguyen Van Kinh; Dao Tuyet Trinh; Tran Tinh Hien; Tran Tinh Hien
Published in: eLife, Issue 1, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.68917

Asynchrony between virus diversity and antibody selection limits influenza virus evolution

Author(s): Dylan H Morris, Velislava N Petrova, Fernando W Rossine, Edyth Parker, Bryan T Grenfell, Richard A Neher, Simon A Levin, Colin A Russell
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.62105

SARS-CoV-2 diagnostic testing rates determine the sensitivity of genomic surveillance programs

Author(s): Alvin X. Han, Amy Toporowski, Jilian A. Sacks, Mark D. Perkins, Sylvie Briand, Maria van Kerkhove, Emma Hannay, Sergio Carmona, Bill Rodriguez, Edyth Parker, Brooke E. Nichols, Colin A. Russell
Published in: Nature Genetics, 2023, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-022-01267-w

Antigenic cartography using sera from sequence-confirmed SARS-CoV-2 variants of concern infections reveals antigenic divergence of Omicron

Author(s): Karlijn van der Straten, Denise Guerra, Marit J van Gils, Ilja Bontjer, Tom G Caniels, Hugo DG van Willigen, Elke Wynberg, Meliawati Poniman, Judith A Burger, Joey H Bouhuijs, Jacqueline van Rijswijk, Wouter Olijhoek, Marinus H Liesdek, AH Lavell, Brent Appelman, Jonne J Sikkens, Marije K Bomers, Alvin X Han, Brooke E Nichols, Maria Prins, Harry Vennema, Chantal Reusken, Marije Menno D de Jong, Go
Published in: Immunity, 2022, ISSN 1074-7613
Publisher: Cell Press
DOI: 10.1016/j.immuni.2022.07.018

Co-evolution of immunity and seasonal influenza viruses

Author(s): Alvin X. Han, Simon P. J. de Jong, Colin A. Russell
Published in: Nature Reviews Microbiology, Issue 21, 2023, Page(s) 805-817, ISSN 1740-1526
Publisher: Nature Publishing Group
DOI: 10.1038/s41579-023-00945-8