Repurposing small RNA from ciliates for genome editing: single-molecule study

Project Information

MIGHTY_RNA

Grant agreement ID: 819299

DOI 10.3030/819299

Project closed

EC signature date 18 December 2018

Start date 1 May 2019

End date 30 April 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 792 850,00

EU contribution € 1 792 850,00

Coordinated by

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

Publications

Peer reviewed articles (7)

the road to next-generation single-molecule biophysics

Author(s): Severins, I.W.H.; Joo, C.; Noort, S.J.T. van
Published in: Molecular Cell, Issue 4, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.04.024

mRNA structural dynamics shape Argonaute-target interactions

Author(s): Suzan Ruijtenberg, Stijn Sonneveld, Tao Ju Cui, Ive Logister, Dion de Steenwinkel, Yao Xiao, Ian J. MacRae, Chirlmin Joo, Marvin E. Tanenbaum
Published in: Nature Structural & Molecular Biology, Issue 27/9, 2020, Page(s) 790-801, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-020-0461-1

High-Speed Super-Resolution Imaging Using Protein-Assisted DNA-PAINT

Author(s): Mike Filius, Tao Ju Cui, Adithya N. Ananth, Margreet W. Docter, Jorrit W. Hegge, John van der Oost, Chirlmin Joo
Published in: Nano Letters, Issue 20/4, 2020, Page(s) 2264-2270, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.9b04277

FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

Author(s): Lerner, Eitan; Barth, Anders; Hendrix, Jelle; Ambrose, Benjamin; Birkedal, Victoria; Blanchard, Scott C.; Börner, Richard; Chung, Hoi Sung; Cordes, Thorben; Craggs, Timothy D.; Deniz, Ashok A.; Diao, Jiajia; Fei, Jingyi; Gonzalez, Ruben L.; Gopich, Irina V.; Ha, Taekjip; Hanke, Christian A.; Haran, Gilad; Hatzakis, Nikos S.; Hohng, Sungchul; Hong, Seok Cheol; Hugel, Thorsten; Ingargiola, Antonino
Published in: eLife, Issue 2, 2021, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.60416

Argonaute bypasses cellular obstacles without hindrance during target search

Author(s): Tao Ju Cui, Misha Klein, Jorrit W. Hegge, Stanley D. Chandradoss, John van der Oost, Martin Depken, Chirlmin Joo
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12415-y

Targeting G-quadruplex Forming Sequences with Cas9

Author(s): Hamza Balci; Hamza Balci; Viktorija Globyte; Chirlmin Joo
Published in: ACS Chemical Biology, Issue 2, 2021, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1101/2020.09.19.304816

Small RNA-directed DNA elimination: the molecular mechanism and its potential for genome editing.

Author(s): C.K.J.M.L. Bastiaanssen; Chirlmin Joo
Published in: RNA Biology, Issue 2, 2021, ISSN 1547-6286
Publisher: Landes Bioscience
DOI: 10.1080/15476286.2021.1885208