Novel mitochondria-targeted therapies for cancer treatment-induced cardiotoxicity

Informazioni relative al progetto

MATRIX

ID dell’accordo di sovvenzione: 819775

DOI 10.3030/819775

Data della firma CE 29 Aprile 2019

Data di avvio 1 Settembre 2019

Data di completamento 31 Maggio 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 999 375,00

Contributo UE € 1 999 375,00

Coordinato da

CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
Spain

Pubblicazioni

Peer reviewed articles (9)

Cardiac Magnetic Resonance Protocol Including Single Breath-Hold 3-Dimensional Sequences

Autori: Gómez-Talavera S, Fernandez-Jimenez R, Fuster V, Nothnagel ND, Kouwenhoven M, Clemence M, García-Lunar I, Gómez-Rubín MC, Navarro F, Pérez-Asenjo B, Fernández-Friera L, Calero MJ, Orejas M, Cabrera JA, Desco M, Pizarro G, Ibáñez B, Sánchez-González J.
Pubblicato in: Journal of the American College of Cardiology (JACC), Numero 18767591, 2021, ISSN 1876-7591
Editore: Elsevier
DOI: 10.1016/j.jcmg.2021.02.031

Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection

Autori: Heusch, Gerd; Andreadou, Ioanna; Bell, Robert; Bertero, Edoardo; Botker, Hans-Erik; Davidson, Sean M.; Downey, James; Eaton, Philip; Ferdinandy, Peter; Gersh, Bernard J.; Giacca, Mauro; Hausenloy, Derek J.; Ibanez, Borja; Krieg, Thomas; Maack, Christoph; Schulz, Rainer; Sellke, Frank; Shah, Ajay M.; Thiele, Holger; Yellon, Derek M.; Di Lisa, Fabio
Pubblicato in: REDOX BIOLOGY, Numero 2023 Nov:67:10289 // Fifty issues a year, 2023, Pagina/e 1-46, ISSN 2213-2317
Editore: Elsevier BV
DOI: 10.1016/j.redox.2023.102894

A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

Autori: Nicolas-Avila, Jose A.; Lechuga-Vieco, Ana V.; Esteban-Martinez, Lorena; Sanchez-Diaz, Maria; Diaz-Garcia, Elena; Santiago, Demetrio J.; Rubio-Ponce, Andrea; Li, Jackson LiangYao; Balachander, Akhila; Quintana, Juan A.; Martinez-de-Mena, Raquel; Castejon-Vega, Beatriz; Pun-Garcia, Andres; Traves, Paqui G.; Bonzon-Kulichenko, Elena; Garcia-Marques, Fernando; Cusso, Lorena; A-Gonzalez, Noelia; Gonza
Pubblicato in: CELL, Numero 2020 Oct 1;183(1) // Biweekly, 2020, ISSN 0092-8674
Editore: Cell Press
DOI: 10.1016/j.cell.2020.08.031

Cardiac Mitochondrial Transplantation: The Force Awakens.

Autori: Ibáñez, Borja; Villena-Gutierrez, Rocio
Pubblicato in: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Numero 5, 2021, ISSN 0735-1097
Editore: Elsevier BV
DOI: 10.1016/j.jacc.2021.01.017

Remote ischaemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity

Autori: Carlos Galán-Arriola, Rocio Villena-Gutiérrez, María I Higuero-Verdejo, Iván A Díaz-Rengifo, Gonzalo Pizarro, Gonzalo J López, Antonio de Molina-Iracheta, Claudia Pérez-Martínez, Rodrigo D García, David González-Calle, Manuel Lobo, Pedro L Sánchez, Eduardo Oliver, Raúl Córdoba, Valentin Fuster, Javier Sánchez-González, Borja Ibanez
Pubblicato in: Cardiovascular Research, Numero 117/4, 2020, Pagina/e 1132-1143, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvaa181

Coronary microcirculation damage in anthracycline cardiotoxicity

Autori: Carlos Galán-Arriola, Jean Paul Vílchez-Tschischke, Manuel Lobo, Gonzalo J López, Antonio de Molina-Iracheta, Claudia Pérez-Martínez, Rocio Villena-Gutiérrez, Álvaro Macías, Iván A Díaz-Rengifo, Eduardo Oliver, Valentin Fuster, Javier Sánchez-González, Borja Ibanez
Pubblicato in: Cardiovascular Research, 2021, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab053

T cells with dysfunctional mitochondria induce multimorbidity and premature senescence

Autori: Desdin-Mico, Gabriela; Soto-Heredero, Gonzalo; Francisco Aranda, Juan; Oller, Jorge; Carrasco, Elisa; Gabande-Rodriguez, Enrique; Maria Blanco, Eva; Alfranca, Arantzazu; Cusso, Lorena; Desco, Manuel; Ibanez, Borja; Gortazar, Arancha R.; Fernandez-Marcos, Pablo; Navarro, Maria N.; Hernaez, Bruno; Alcami, Antonio; Baixauli, Francesc; Mittelbrunn, Maria
Pubblicato in: SCIENCE, Numero 2020 Jun 19;368(6497) // Weekly, 2020, Pagina/e 1371-1376, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aax0860

The Quest for an Early Marker of Anthracycline-Induced Cardiotoxicity

Autori: Ibáñez, Borja; Moreno-Arciniegas, Andrea
Pubblicato in: JACC: Basic to Translational Science, Numero 9, 2022, ISSN 2452-302X
Editore: ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacbts.2021.11.010

Beta-3 adrenergic receptor overexpression reverses aortic stenosis–induced heart failure and restores balanced mitochondrial dynamics

Autori: Andrés Pun-García; Agustín Clemente-Moragón; Rocio Villena-Gutierrez; Monica Gómez; David Sanz-Rosa; Anabel Díaz-Guerra; Belén Prados; Juan Pablo Medina; Fermí Montó; Maria Dolores Ivorra; Cristina Márquez-López; Alessandro Cannavo; Juan A. Bernal; Walter J. Koch; Valentin Fuster; José Luis de la Pompa; Eduardo Oliver; Borja Ibanez
Pubblicato in: Pun García, Andrés Clemente Moragón, Agustín Villena Gutierrez, Rocio Gómez, Mónica Sanz Rosa, David Díaz Guerra, Anabel Prados, Belén Medina, Juan Pablo Montó Guillot, Fermí Josep Ivorra Insa, María Dolores Márquez-López, Cristina Cannavo, Alessandro Bernal, Juan A. Koch, Walter J. Fuster, Valentin De la Pompa, Jose Luis Oliver Pérez, Eduardo Ibanez, Borja 2022 Beta-3 adrenergic rec, Numero 1, 2022, ISSN 0300-8428
Editore: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-022-00966-z

Other (1)

Remote Ischemic Conditioning for Anthracycline Cardiotoxicity The Need to Protect the Most Vulnerable

Autori: Ibanez, Borja; Gomes-Silva, Maria
Pubblicato in: JACC: CARDIOONCOLOGY, Numero 2023 Jun 20;5(3) // Six issues a year, 2023, Pagina/e 356-359, ISSN 2666-0873
Editore: ELSEVIER
DOI: 10.1016/j.jaccao.2023.05.002