Innovation in Tuberculosis

Leistungen

Open access publications about the study of metabolome and exhaled compounds

Open access publications about the study of the urinary metabolome by NMR, blood metabolome by GC/LC-MS, and volatile compounds in exhaled air by FAIMS.

Open access publications about the improvement of TB therapy strategies

Open access publications describing the characterization of macrophage surface target markers, the development of a new anti-TB drug delivery approach based on nanoparticles, and the study of new biomarkers to individualize the therapy duration

Open access publication about the study of primary immunodeficiencies

Publication describing the study of primary immunodeficiencies with Whole Exome Sequencing

Open access publication(s) about the study of the Host-Pathogen interaction

Publications describing the characterization of the immunologic response of CD4 and CD8 Tcells expressing CD27 andor CCR4 surface markers the study of the host immune response against different M tuberculosis antigens by means Luminex and flow cytometry and the transcriptomic approach for a specific blood signature of progression to active TB

Mid-term meeting

Meeting of all the partners in the consortium, with workshops, training, networking, and communication and dissemination activities.

Veröffentlichungen

Diagnostic Performance of the Fujifilm SILVAMP TB-LAM in Children with Presumptive Tuberculosis

Autoren: Patricia Comella-del-Barrio, Bárbara Molina-Moya, Jacqueline Gautier, Raquel Villar-Hernández, Mariette Jean Coute Doresca, Beatriz Sallés-Mingels, Lydia Canales-Aliaga, Margareth Narcisse, Tomás M. Pérez-Porcuna, Jacob Creswell, Luis E. Cuevas, José Domínguez
Veröffentlicht in: Journal of Clinical Medicine, Ausgabe 10/9, 2021, Seite(n) 1914, ISSN 2077-0383
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10091914

Molecular Detection of Mycobacterium tuberculosis in Oral Mucosa from Patients with Presumptive Tuberculosis

Autoren: Barbara Molina-Moya, Nelly Ciobanu, Marta Hernandez, Cristina Prat-Aymerich, Valeriu Crudu, Emily R. Adams, Alexandru Codreanu, Derek J. Sloan, Luis E. Cuevas, Jose Dominguez
Veröffentlicht in: Journal of Clinical Medicine, Ausgabe 9/12, 2020, Seite(n) 4124, ISSN 2077-0383
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9124124

Remote analysis of sputum smears for mycobacterium tuberculosis quantification using digital crowdsourcing

Autoren: Lara García Delgado, María Postigo, Daniel Cuadrado, Sara Gil-Casanova, Álvaro Martínez Martínez, María Linares, Paloma Merino, Manuel Gimo, Silvia Blanco, Quique Bassat, Andrés Santos, Alberto L García-Basteiro, María J Ledesma-Carbayo, Miguel Á Luengo-Oroz
Veröffentlicht in: PLoS One, Ausgabe 19326203, 2022, ISSN 1932-6203
Herausgeber: Public Library of Science
DOI: 10.1371/journal.pone.0268494

Impact of COVID-19 on Tuberculosis Control

Autoren: Patricia Comella-del-Barrio, Maria Luiza De Souza-Galvão, Cristina Prat-Aymerich, José Domínguez
Veröffentlicht in: Archivos de Bronconeumología, 2020, ISSN 0300-2896
Herausgeber: Ediciones Doyma S.A.
DOI: 10.1016/j.arbres.2020.11.016

Fujifilm SILVAMP TB-LAM for the Diagnosis of Tuberculosis in Nigerian Adults

Autoren: Patricia Comella-del-Barrio, John S. Bimba, Ramota Adelakun, Konstantina Kontogianni, Bárbara Molina-Moya, Okoedoh Osazuwa, Jacob Creswell, Luis E. Cuevas, José Domínguez
Veröffentlicht in: Journal of Clinical Medicine, Ausgabe 10/11, 2021, Seite(n) 2514, ISSN 2077-0383
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10112514

Study of CD27, CD38, HLA-DR and Ki-67 immune profiles for the characterization of active tuberculosis, latent infection and end of treatment

Autoren: Sergio Díaz-Fernández, Raquel Villar-Hernández, Zoran Stojanovic, Marco Fernández, Maria Luiza De Souza Galvão, Guillermo Tolosa, Adrián Sánchez-Montalva, Jorge Abad, María Ángeles Jiménez-Fuentes, Guillem Safont, Iris Romero, Josefina Sabrià, Cristina Prat, Jose Domínguez, Irene Latorre
Veröffentlicht in: Frontiers in Microbiology, 2022, ISSN 1664-302X
Herausgeber: Frontiers Media
DOI: 10.3389/fmicb.2022.885312

Urine NMR-based TB metabolic fingerprinting for the diagnosis of TB in children

Autoren: Patricia Comella-del-Barrio, José Luis Izquierdo-Garcia, Jacqueline Gautier, Mariette Jean Coute Doresca, Ramón Campos-Olivas, Clara M. Santiveri, Beatriz Muriel-Moreno, Cristina Prat-Aymerich, Rosa Abellana, Tomas M. Pérez-Porcuna, Luis E. Cuevas, Jesús Ruiz-Cabello, José Domínguez
Veröffentlicht in: Scientific Reports, Ausgabe 11/1, 2021, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-021-91545-0

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